CN104672202B - 作为联蛋白信号通路激活剂的二酮与羟基酮 - Google Patents

作为联蛋白信号通路激活剂的二酮与羟基酮 Download PDF

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CN104672202B
CN104672202B CN201510019522.0A CN201510019522A CN104672202B CN 104672202 B CN104672202 B CN 104672202B CN 201510019522 A CN201510019522 A CN 201510019522A CN 104672202 B CN104672202 B CN 104672202B
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CN104672202A (zh
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S·K·克西
D·M·华莱士
J·胡德
C·F·巴罗加
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WINTHERIX LLC
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CN201510019522.0A 2010-08-18 2011-08-17 作为联蛋白信号通路激活剂的二酮与羟基酮 Active CN104672202B (zh)

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DK2987487T3 (da) 2009-08-10 2020-12-07 Samumed Llc Indazolinhibitorer af wnt-signalvejen og terapeutiske anvendelser deraf
SMT201800065T1 (it) * 2010-08-18 2018-03-08 Samumed Llc Dichetoni e idrossichetoni come attivatori della via di segnalazione della catechina
US20140037599A1 (en) * 2012-08-03 2014-02-06 The Trustees Of The University Of Pennsylvania Compositions and Methods of Treating T Cell Deficiency
EP2968249B1 (en) * 2013-02-22 2018-11-14 Samumed, LLC Gamma-diketones as wnt/beta -catenin signaling pathway activators
ES2762559T3 (es) * 2014-08-20 2020-05-25 Samumed Llc Gamma-dicetonas para tratamiento y prevención de envejecimiento de la piel y arrugas
IL319729A (en) * 2016-07-19 2025-05-01 Accellta Ltd Medium for growing pluripotent stem cells in suspension
BR112019013388A2 (pt) 2016-12-30 2020-03-03 Frequency Therapeutics, Inc. Compostos de 1h-pirrol-2,5-diona e métodos de uso dos mesmos para induzir a autorrenovação de células de suporte tronco/progenitoras
WO2020037323A1 (en) 2018-08-17 2020-02-20 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by upregulating jag-1
EP3837351A1 (en) 2018-08-17 2021-06-23 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by downregulating foxo
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