CN104661819B - 包装材料以及使用其而成的包装结构 - Google Patents

包装材料以及使用其而成的包装结构 Download PDF

Info

Publication number
CN104661819B
CN104661819B CN201380049093.0A CN201380049093A CN104661819B CN 104661819 B CN104661819 B CN 104661819B CN 201380049093 A CN201380049093 A CN 201380049093A CN 104661819 B CN104661819 B CN 104661819B
Authority
CN
China
Prior art keywords
moles
packaging material
patch
internal layer
copolymerization ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201380049093.0A
Other languages
English (en)
Other versions
CN104661819A (zh
Inventor
石崎庸
石崎庸一
太田芳弘
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Seikan Group Holdings Ltd
Original Assignee
Toyo Seikan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Seikan Kaisha Ltd filed Critical Toyo Seikan Kaisha Ltd
Publication of CN104661819A publication Critical patent/CN104661819A/zh
Application granted granted Critical
Publication of CN104661819B publication Critical patent/CN104661819B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00072—Packaging of dressings
    • A61F13/00076—Packaging of adhesive dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B32B15/09—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyesters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/20—Layered products comprising a layer of metal comprising aluminium or copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
    • B65D65/38—Packaging materials of special type or form
    • B65D65/40—Applications of laminates for particular packaging purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00544—Plasters form or structure
    • A61F2013/00646—Medication patches, e.g. transcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00897—Plasters package for individual plaster
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/00906—Plasters containing means for transcutaneous or transdermal drugs application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/03—3 layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/04—4 layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/24—All layers being polymeric
    • B32B2250/244—All polymers belonging to those covered by group B32B27/36
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/30—Properties of the layers or laminate having particular thermal properties
    • B32B2307/31—Heat sealable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/514—Oriented
    • B32B2307/518—Oriented bi-axially
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/724—Permeability to gases, adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/724—Permeability to gases, adsorption
    • B32B2307/7242—Non-permeable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2311/00—Metals, their alloys or their compounds
    • B32B2311/24—Aluminium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00—Containers; Receptacles
    • B32B2439/80—Medical packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y10T428/31565—Next to polyester [polyethylene terephthalate, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y10T428/31605—Next to free metal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal
    • Y10T428/31681—Next to polyester, polyamide or polyimide [e.g., alkyd, glue, or nylon, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31786—Of polyester [e.g., alkyd, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Laminated Bodies (AREA)
  • Wrappers (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明提供一种包装材料，其为贴剂用的包装材料，包含由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜以及基材薄膜，前述内层薄膜的热封面由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂构成。更优选由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜为至少具有如下2层的多层薄膜：由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的热封面侧层；和由间苯二甲酸成分的共聚比率为0摩尔％～5摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的层。

Description

包装材料以及使用其而成的包装结构
技术领域
本发明涉及贴剂用的包装材料、尤其涉及在粘合剂中含有油状成分而成的贴剂用的包装材料。
背景技术
对于贴剂、特别是在粘合剂层中含有药物的经皮吸收用贴剂，从保存中的品质保持等观点出发，使用密闭性的包装材料来进行密封包装。然而，用包装材料包装在粘合剂中含有油状成分的贴剂时，存在贴剂接触于包装材料的内表面，从而油状成分吸附或移动到包装材料，使粘合剂中的油状成分的含量发生变化，粘合特性发生变化的问题。此外，经皮吸收用贴剂的情况下，被指出如下问题：所含药物的经皮吸收性降低、所含药物自身的吸附导致的药理效果的降低等。
对于上述问题，提出由乙烯/乙烯醇共聚物或丙烯腈/丙烯酸甲酯共聚物形成包装材料的内表面(日本特开平5-305108号公报)。此外，提出密封层为由无拉伸聚酯形成的包装袋(日本特开平9-39982号公报)
然而，乙烯/乙烯醇共聚物或丙烯腈/丙烯酸甲酯共聚物昂贵，正在谋求它们的替代品。此外，即使在使用无拉伸聚酯的情况下，也正在谋求进一步提高作为包装材料的性能、尤其以高水平兼具热封性与非吸附性。
发明内容
本发明的目的在于提供防止贴剂的粘合剂中含有的油状成分吸附或移动到包装材料，并且具有优异的热封特性的包装材料。
本发明提供一种包装材料，其包含由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜以及基材薄膜，前述内层薄膜的热封面由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂构成。
本发明的包装材料中优选：
(1)内层薄膜为至少具有如下2层的多层薄膜：由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的热封面侧层；和由间苯二甲酸成分的共聚比率为0摩尔％～5摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的层，
(2)为贴剂用的包装材料，
(3)贴剂为使含有经皮吸收性药物的粘合剂层形成于支撑体的单面而成的经皮吸收制剂。
此外，本发明的包装结构中优选：
(4)用上述的包装材料包装贴剂而成的包装结构，
(5)贴剂为使含有经皮吸收性药物的粘合剂层形成于支撑体的单面而成的经皮吸收制剂。
根据本发明，实现了防止贴剂的粘合剂中含有的油状成分吸附或移动到包装材料、并且具有优异的热封特性的包装材料。
具体实施方式
本发明的包装材料为包含由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜以及基材薄膜，前述内层薄膜的热封面由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％、优选12摩尔％～18摩尔％、特别优选14摩尔％～16摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂构成的包装材料。
作为具有热封性的聚对苯二甲酸乙二醇酯系树脂使用的间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂对于油状成分的非吸附性优异、并且具有优异的热封性。因此，前述聚对苯二甲酸乙二醇酯树脂作为构成可以防止贴剂中的油状成分向包装材料移动的包装材料的热封面的材料是优异的。间苯二甲酸的共聚比率不足10摩尔％时，由于制膜时的结晶化导致热封性降低。此外，共聚比率超过20摩尔％时，非吸附性降低。
进而，由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜特别优选为具有如下2层的多层薄膜：由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％、优选12摩尔％～18摩尔％、特别优选14摩尔％～16摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的热封面侧层；和由间苯二甲酸成分的共聚比率为0摩尔％～5摩尔％、优选0.1摩尔％～4摩尔％、特别优选1摩尔％～3摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的层(即，与基材薄膜相对侧的层)。
间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的较高改性率的聚对苯二甲酸乙二醇酯的结晶性低，因此热封特性优异，并且具有优异的非吸附性，然而，间苯二甲酸成分的共聚比率为0摩尔％～5摩尔％的低改性率的聚对苯二甲酸乙二醇酯具有更高的非吸附性。此外，低改性率的聚对苯二甲酸乙二醇酯通常大量作为塑料瓶用材料而使用，因此可以廉价地供应、经济性优异。即，将由聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜制成上述的多层构成，由此可以实现热封特性、非吸附性以及经济性优异的内层薄膜。
在不损害热封特性以及非吸附性的范围内，内层薄膜中也可以添加各种添加剂。作为添加剂，可以列举出抗氧化剂、紫外线吸收剂、水解抑制剂、防霉剂、固化催化剂、增塑剂、颜料、填充剂、润滑剂等。
内层薄膜的厚度为10μm～30μm、特别优选为15μm～28μm。厚度大于其上限时，有可能非吸附性降低、或撕裂性上产生问题，此外，厚度小于其下限时，有可能热封强度降低、或包装材料的硬挺度受损而给商品性带来问题。内层薄膜为多层构成时，热封面侧层的厚度优选为2～20μm、特别优选为3～10μm。对于低改性率的聚对苯二甲酸乙二醇酯层的厚度，可以结合热封面侧层的厚度适当地设定，以使获得所期望的内层薄膜整体的厚度，优选为10～28μm、特别优选为15～25μm。
内层薄膜可以用T口模成型、吹塑成型等公知的制膜方法进行制膜。此时，优选通过使热熔融状态的膜急速冷却得以进行固化。通过急速冷却，从而抑制树脂的结晶化，得到热封特性优异的薄膜。
此外，优选内层薄膜为无拉伸或者以低倍率拉伸的状态。以高倍率拉伸的聚对苯二甲酸乙二醇酯由于取向结晶化而失去热封性，因此不优选。
作为基材薄膜没有特别限定，从透明性、印刷适应性、耐化学试剂性以及强度优异的观点出发，可以使用双轴拉伸聚对苯二甲酸乙二醇酯、双轴拉伸聚酰胺、双轴拉伸聚丙烯薄膜等。基材薄膜的厚度(除下述阻气层以外)优选为5～20μm、特别优选为10～15μm。
进而，为了防止氧气、水蒸汽的透过性，还优选层叠阻气层。作为阻气层，可以使用铝箔。铝箔不仅对氧气、水蒸汽的阻隔性优异，而且遮光性也优异，可以适当地使用。在层叠有阻气层的情况下，其厚度优选为2～20μm、特别优选为5～10μm。
包装材料的制造可以使用其自身公知的成型法。例如，根据树脂的种类使用多个挤出机，使用多层多重口模进行挤出成型，从而可以成型层叠体。进而，可以使用挤出涂布法、三明治层压，此外，也可以通过预先形成的薄膜的干燥层压从而制造层叠体。例如如上所述，在预先利用T口模法等成膜由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜时，利用干压法将该内层薄膜层叠于由双轴拉伸聚对苯二甲酸乙二醇酯形成的基材薄膜上，从而得到本发明的贴剂用包装材料。
层叠体可以通过制成三边密封或四边密封的通常的袋类、折边袋类、立式袋类、枕式袋类等，从而制成包装袋。制袋可以用公知的制袋法来进行。
用上述包装材料包装的贴剂包括支撑体层与粘合剂层，粘合剂层中配合药物、使药物经皮吸收从而进行各种疾病的治疗或预防。这里所谓药物没有特别限定，可以使用全身性用药、局部用药的任一种。作为这样的药物，例如，可以列举出肾上腺皮质类固醇剂、非类固醇类消炎剂、抗风湿剂、安眠药、抗精神病剂、抗抑郁剂、稳定情绪剂、兴奋剂、镇静剂、抗癫痫剂、偏头痛治疗剂、帕金森氏病治疗剂、蕈毒碱受体拮抗剂、不安腿综合征治疗剂、脑循环/代谢改善剂、抗痴呆剂、自主神经作用剂、肌肉松弛剂(muscle-relaxantdrug)、降压剂、利尿剂、降血糖剂、抗高血脂剂、痛风治疗剂、全身麻醉剂、局部麻醉剂、抗菌剂、抗真菌剂、抗病毒药物、抗寄生虫剂、维他命剂、心绞痛治疗剂、血管扩张剂、抗心律失常剂、抗组胺剂、介质释放抑制剂、白三烯拮抗剂性激素剂、甲状腺激素剂、抗甲状腺剂、抗肿瘤剂、止吐剂、止晕剂(antidinic)、支气管扩张剂、镇咳剂、祛痰剂、戒烟辅助剂、抗骨质疏松症剂等。这些药物可以以游离物的形态使用、也可以以盐的形态使用。此外，这些药物可以单独使用或混合使用2种以上。
作为支撑体层，若在贴附时没有明显的违和感则没有特别限定。具体而言，可以列举出由聚酯、聚乙烯或者聚丙烯等聚烯烃，聚氯乙烯、增塑化聚氯乙烯、增塑化醋酸乙烯酯-氯乙烯共聚物、聚偏二氯乙烯、乙烯-醋酸乙烯酯共聚物、醋酸纤维素、乙基纤维素、乙烯-丙烯酸乙酯共聚物、聚四氟乙烯、聚氨酯、离聚物树脂等合成树脂形成的单一薄膜或它们的层压薄膜、或者橡胶制、上述合成树脂制、聚对苯二甲酸乙二醇酯等聚酯制、或尼龙等聚酰胺制的多孔性薄膜或者片、无纺布、织物或它们与上述合成树脂薄膜的层压物等。
贴剂为经皮吸收制剂，优选使含有经皮吸收性药物的粘合剂层形成于支撑体的单面而成的贴剂。此外，可以具有层叠于该粘合剂层的另一面的经过剥离处理的脱模薄膜。
作为贴剂的形态，为平面状的扁平的形态，平面形状除基本矩形以外，可以列举出三角形、五角形等多边形、即以轮廓大致呈直线的形状；椭圆、圆形等轮廓呈曲线的形状；它们的组合等，但并不限定于它们。
贴剂的大小可以根据贴剂的用途、应用位置等适当地选择。例如，贴剂的形状大致为矩形时，一般而言，其一边的长度为15mm～90mm、另一边的长度也为15mm～90mm。
贴剂的总厚度通常为50μm～2000μm、优选为100μm～1000μm的范围。此外，贴剂包含支持层与粘合剂层，支撑体层的厚度通常为1μm～1000μm、粘合剂层的厚度通常为10μm～200μm、优选为15μm～150μm。
粘合剂层中也可以含有油状成分。含有的油状成分使粘合剂层增塑化、赋予柔软感，从而降低皮肤刺激性、或调整药物的经皮吸收性。油状成分优选在室温(25℃)下为液态的物质、或混合使用2种以上时最终的混合物在室温(25℃)下为液态的物质。作为这样的油状成分，例如，可以列举出油醇、辛基十二烷醇等高级醇；甘油、乙二醇、聚丙二醇等多元醇；辛酸、油酸等高级脂肪酸；肉豆蔻酸异丙酯、棕榈酸异丙酯、油酸乙酯等脂肪酸酯；癸二酸二乙酯、己二酸二异丙酯等多元酸酯；三异硬脂二甘油酯、失水山梨醇单油酯、二辛酸丙二醇酯、单月桂酸聚乙二醇酯、四油酸聚氧乙烯山梨醇酯等多元醇脂肪酸酯；聚氧乙烯月桂基醚等聚氧乙烯烷基醚；角鲨烯、液体石蜡等烃；橄榄油、蓖麻油等植物油；硅油；N-甲基吡咯烷酮、N-十二烷基吡咯烷酮那样的吡咯烷酮类；癸基甲基亚砜那样的亚砜类等。这些油状成分可以单独或混合使用2种以上。
本发明的贴剂用的包装体的形状若为可以包装贴剂那样的形状则没有特别限定，例如，除正方形、长方形等基本矩形之外，可以列举出三角形、五角形等多边形，圆形、椭圆形、其它的图形等。此外，贴剂用的包装体的形状与被包装的贴剂的形状只要可以分别包装(密封)贴剂，则可以为相同的也可以为不同的。
实施例
以下，利用实施例具体地说明本发明。各值通过以下的方法而测定。
(1)热封强度
使用热封试验装置(TESTER SANGYO CO,.LTD.制造)，密封时间0.8秒、将密封压固定为2kgf/cm2，改变密封温度边测定密封界面的温度边制作试验片。热封强度的测定以JIS-Z1707为基准，在23℃、50％RH环境下使用精密万能试验机Autogragh AG-IS(岛津制作所株式会社制造)进行测定。沿薄膜的流动方向(MD)以300mm/分钟的速度拉伸，将最大试验力(N/15mm)作为热封强度，对密封界面温度作图，制作热封曲线。在此，将热封强度达到1N/15mm的密封界面温度作为密封表现温度，与密封界面温度110℃下的热封强度一起用于评价热封特性。将满足密封表现温度90℃以下并且110℃下的密封强度为15N/15mm以上这两个条件的包装材料设为热封特性良好。
(2)油状成分的非吸附性
将包装材料6cm×10cm的试验片在肉豆蔻酸异丙酯气氛中在50℃下静置6天，然后用60ml己烷在50℃下提取24小时，用气相色谱对提取液中的肉豆蔻酸异丙酯进行定量。结果以将比较例1的包装材料的测定结果作为100时的相对值来表示。
[实施例1]
作为基材薄膜，使用了12μm双轴拉伸聚对苯二甲酸乙二醇酯(PET)薄膜与7μm铝箔的干式层压薄膜，作为内层薄膜，使用了由5μm间苯二甲酸改性PET(间苯二甲酸成分共聚比率15摩尔％)以及20μm间苯二甲酸改性PET(间苯二甲酸成分共聚比率2摩尔％)形成的25μm无拉伸2层PET薄膜。使内层薄膜的20μm间苯二甲酸改性PET(间苯二甲酸成分共聚比率2摩尔％)侧与基材薄膜的铝箔侧相对，使用2液固化型聚氨酯系粘结剂利用干压法进行层叠，得到包装材料。将所得到的包装材料的评价结果示出于表1。
[比较例1]
作为内层薄膜，使用了30μmLDPE薄膜(Tamapoly Co.,Ltd制造AJ-3)，除此以外与实施例1同样地操作，得到包装材料。将评价结果在表1中示出。
[比较例2]
作为内层薄膜，使用了30μmPAN薄膜(Tamapoly Co.,Ltd制造HYTRONBX)，除此以外与实施例1同样地操作，得到包装材料。将评价结果在表1中示出。
[比较例3]
作为内层薄膜，使用了25μm无拉伸单层间苯二甲酸改性PET(间苯二甲酸成分共聚比率2摩尔％)，除此以外与实施例1同样地操作，得到包装材料。将评价结果在表1中示出。
[比较例4]
作为内层薄膜，使用了25μm无拉伸单层间苯二甲酸改性PET(间苯二甲酸成分共聚比率5摩尔％)，除此以外与实施例1同样地操作，得到包装材料。将评价结果在表1中示出。
表1
表1

Claims (5)

1.一种包装材料，其包含由具有热封性的聚对苯二甲酸乙二醇酯系树脂形成的内层薄膜以及基材薄膜，所述内层薄膜为至少具有如下2层的多层薄膜：
由间苯二甲酸成分的共聚比率为10摩尔％～20摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的热封面侧层；和
由间苯二甲酸成分的共聚比率为0摩尔％～5摩尔％的间苯二甲酸改性聚对苯二甲酸乙二醇酯树脂形成的层。
2.根据权利要求1所述的包装材料，其为贴剂用的包装材料。
3.根据权利要求2所述的包装材料，其中，贴剂为使含有经皮吸收性药物的粘合剂层形成于支撑体的单面而成的经皮吸收制剂。
4.一种包装结构，其用权利要求2或3所述的包装材料包装贴剂而成。
5.根据权利要求4所述的包装结构，其中，贴剂为使含有经皮吸收性药物的粘合剂层形成于支撑体的单面而成的经皮吸收制剂。
CN201380049093.0A 2012-09-21 2013-09-24 包装材料以及使用其而成的包装结构 Active CN104661819B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012208812A JP6041097B2 (ja) 2012-09-21 2012-09-21 包装材およびそれを用いてなる包装構造
JP2012-208812 2012-09-21
PCT/JP2013/075655 WO2014046277A1 (ja) 2012-09-21 2013-09-24 包装材およびそれを用いてなる包装構造

Publications (2)

Publication Number Publication Date
CN104661819A CN104661819A (zh) 2015-05-27
CN104661819B true CN104661819B (zh) 2016-08-24

Family

ID=50341576

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380049093.0A Active CN104661819B (zh) 2012-09-21 2013-09-24 包装材料以及使用其而成的包装结构

Country Status (7)

Country Link
US (1) US11407212B2 (zh)
EP (1) EP2899024B1 (zh)
JP (1) JP6041097B2 (zh)
KR (1) KR101721180B1 (zh)
CN (1) CN104661819B (zh)
CA (1) CA2883128C (zh)
WO (1) WO2014046277A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6728605B2 (ja) * 2015-09-18 2020-07-22 大日本印刷株式会社 積層体
WO2018009565A1 (en) * 2016-07-06 2018-01-11 Agile Therapeutics, Inc. Transdermal packaging membranes
US11292908B2 (en) 2016-07-20 2022-04-05 Toyo Seikan Group Holdings, Ltd. Easy-to-tear, unstretched resin film and laminate film for packaging material using the same
JP2019107220A (ja) * 2017-12-18 2019-07-04 ニプロ株式会社 貼付剤用包装袋及び貼付剤製品
WO2021039822A1 (ja) * 2019-08-26 2021-03-04 東洋アルミエコープロダクツ株式会社 容器
JP2021171961A (ja) * 2020-04-22 2021-11-01 東洋製罐株式会社 積層フィルム及び包装容器
WO2021257294A1 (en) 2020-06-19 2021-12-23 Proampac Holdings Inc. Recycle-ready retortable laminated polyester-based gusseted pouches
WO2022003099A1 (en) 2020-07-01 2022-01-06 Danapak Flexibles A/S A heat-sealable packaging film
TWI749723B (zh) * 2020-08-20 2021-12-11 南亞塑膠工業股份有限公司 藥物包裝用複合膜材
CN116323213A (zh) * 2020-11-16 2023-06-23 三菱化学株式会社 聚酯系密封剂薄膜

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55166248A (en) * 1979-06-11 1980-12-25 Dainippon Printing Co Ltd Polyester film having heat sealing property and its preparation
JPS6048344A (ja) * 1983-08-26 1985-03-16 藤森工業株式会社 複合包装材料
US4562779A (en) * 1984-01-26 1986-01-07 Briggs Manufacturing, Inc. Foldable drill implement
US4765999A (en) * 1985-07-26 1988-08-23 Presto Products, Incorporated Polyester/copolyester coextruded packaging film
JPS62222845A (ja) * 1986-03-25 1987-09-30 東レ株式会社 熱融着性ポリエステルフイルム
US4946743A (en) * 1987-06-26 1990-08-07 Reynolds Consumer Products, Inc. Nonoriented polyester films for lidding stock with modified heat seal layer
WO1990003886A1 (en) * 1988-10-12 1990-04-19 Toyo Seikan Kaisha, Ltd. Heat-sealable cap for polyester vessel and vessels capped with same
JPH02171240A (ja) * 1988-12-23 1990-07-02 Dainippon Printing Co Ltd 積層シート及び該積層シートによる紙容器
JPH0729406B2 (ja) * 1989-04-19 1995-04-05 凸版印刷株式会社 保香性の優れた積層材料および該積層材料を用いた容器
GB8925785D0 (en) * 1989-11-15 1990-01-04 Ici Plc Multilayer film
JPH03270934A (ja) * 1990-03-20 1991-12-03 Diafoil Co Ltd 積層フィルム、揮発性有害物質用包装体および保護具
US5085904A (en) * 1990-04-20 1992-02-04 E. I. Du Pont De Nemours And Company Barrier materials useful for packaging
WO1993016864A1 (en) * 1992-02-25 1993-09-02 Toray Industries, Inc. Biaxially oriented, laminated polyester film
JP3575616B2 (ja) 1992-05-06 2004-10-13 日東電工株式会社 貼付剤の包装構造
JP3229463B2 (ja) * 1993-10-07 2001-11-19 カネボウ株式会社 ヒートシール性に優れるポリエステルシート及びその成形品
JPH0820094A (ja) * 1994-07-08 1996-01-23 Sekisui Chem Co Ltd 複合包装材料及びそれを用いた包装容器
JPH0939982A (ja) 1995-07-31 1997-02-10 Unitika Res Lab:Kk 包装袋
US5912307A (en) * 1996-05-03 1999-06-15 Bp Amoco Corporation Polyester compositions
US6103857A (en) * 1997-06-19 2000-08-15 Eastman Chemical Company Poly(ethylene terephthalate) (PET) copolymers containing both 1,4-cyclohexanedimethanol and isophthalic acid moieties
WO2000004076A2 (en) * 1998-07-14 2000-01-27 Eastman Chemical Company Polyester comprising a residue of isophthalic acid, terephthalic acid, ethylene glycol and an aromatic diol derivative and a method for identifying the polyester by fluorescence
GB9902299D0 (en) * 1999-02-02 1999-03-24 Du Pont Polymeric film
US6489386B1 (en) * 1999-08-12 2002-12-03 E. I. Du Pont De Nemours And Company Method and composition for improving gas barrier properties of polymeric containers and films
KR100627571B1 (ko) * 1999-11-05 2006-09-22 도요 보세키 가부시키가이샤 금속판 라미네이트용 폴리에스테르계 필름, 필름라미네이트 금속판 및 금속 용기
WO2001040357A1 (fr) * 1999-12-03 2001-06-07 Toray Industries, Inc. Film polyester etire bi-axialement pour formage
DE10015633A1 (de) * 2000-03-29 2001-10-04 Mitsubishi Polyester Film Gmbh Siegelfähige biaxial orientierte Polyesterfolie
JP2001315284A (ja) * 2000-05-12 2001-11-13 Kanebo Ltd ポリエステル積層体
US7759449B2 (en) * 2000-12-15 2010-07-20 Wellman, Inc. Methods for introducing additives into polyethylene terephthalate
DE10112493A1 (de) * 2001-03-15 2002-09-19 Mitsubishi Polyester Film Gmbh Weiße, biaxial orientierte Folie aus einem kristallisierbaren Thermoplasten mit hohem Weißgrad und mit zusätzlicher Funktionalität
DE60314607T2 (de) * 2002-03-07 2007-10-25 Toray Industries, Inc. Polyesterfolie und gasbarrierepolyesterfolie
KR101011290B1 (ko) * 2002-09-10 2011-01-28 도레이 카부시키가이샤 2축 배향 폴리에스테르 필름
US7442427B2 (en) * 2003-04-22 2008-10-28 Mitsubishi Polyester Film Gmbh Coextruded, hot-sealable and peelable polyester film, process for its production and its use
US20050261462A1 (en) * 2004-05-20 2005-11-24 Nichols Carl S Methods of making titanium-catalyzed polyester resins
JP2007504352A (ja) * 2003-05-21 2007-03-01 ウェルマン・インコーポレーテッド 遅延性結晶化ポリエステル樹脂
US20070059465A1 (en) * 2004-05-20 2007-03-15 Thompson David E Polyester Resins for High-Strength Articles
JPWO2005072675A1 (ja) * 2004-01-30 2007-09-13 久光製薬株式会社 貼付剤入り包装袋及び薬物移行抑制方法
GB0500907D0 (en) * 2005-01-17 2005-02-23 Dupont Teijin Films Us Ltd Self-venting polymeric film IV
JP4672429B2 (ja) * 2005-05-02 2011-04-20 藤森工業株式会社 積層フィルムのシーラント層の形成方法、積層フィルムの製造方法および包装袋の製造方法
EP1728815B1 (de) * 2005-06-01 2008-07-23 Mitsubishi Polyester Film GmbH Weiss-opake Folie mit niedriger Transparenz und verbesserter Durchschlagsfestigkeit
DE102005027657A1 (de) * 2005-06-15 2006-12-21 Mitsubishi Polyester Film Gmbh Mehrschichtige, transparente Polyesterfolie mit hoher Sauerstoffbarriere
WO2007059128A1 (en) * 2005-11-15 2007-05-24 Wellman, Inc. Alumina-enhanced polyester resins
WO2008008813A2 (en) * 2006-07-11 2008-01-17 Wellman, Inc. Solid phase polymerization catalyst system
US8945702B2 (en) * 2007-10-31 2015-02-03 Bemis Company, Inc. Barrier packaging webs having metallized non-oriented film
DE102007054133A1 (de) * 2007-11-14 2009-05-20 Mitsubishi Polyester Film Gmbh Antimikrobiell ausgerüstete, gecoatete, biaxial orientierte Polyesterfolie
DE102007054132A1 (de) * 2007-11-14 2009-05-20 Mitsubishi Polyester Film Gmbh Antimikrobiell ausgerüstete, biaxial orientierte Polyesterfolie
US7714094B2 (en) * 2007-11-15 2010-05-11 Eastman Chemical Company Simplified isophthalic acid process for modifying PET
JP5244553B2 (ja) * 2008-11-17 2013-07-24 日東電工株式会社 ブリスター包装体
KR20120024562A (ko) 2009-04-24 2012-03-14 히사미쓰 세이야꾸 가부시키가이샤 첩부제 수용 포장 백, 및 첩부제의 보존 방법
US20100280152A1 (en) * 2009-04-29 2010-11-04 Spartech Corporation Thermoformable and RF Sealable Plastic Packaging Material
EP2491067B1 (en) * 2009-10-19 2015-09-09 Eastman Chemical Company Radio-frequency sealable polymer and articles thereof
CN102218881B (zh) * 2011-03-29 2014-06-25 奥瑞金包装股份有限公司 低表面能聚酯薄膜、其制备方法及用途
US11292908B2 (en) * 2016-07-20 2022-04-05 Toyo Seikan Group Holdings, Ltd. Easy-to-tear, unstretched resin film and laminate film for packaging material using the same

Also Published As

Publication number Publication date
CA2883128C (en) 2018-05-01
CN104661819A (zh) 2015-05-27
EP2899024A1 (en) 2015-07-29
KR101721180B1 (ko) 2017-03-29
EP2899024B1 (en) 2018-07-25
KR20150056852A (ko) 2015-05-27
JP2014061663A (ja) 2014-04-10
JP6041097B2 (ja) 2016-12-07
US11407212B2 (en) 2022-08-09
EP2899024A4 (en) 2016-05-25
CA2883128A1 (en) 2014-03-27
US20150258757A1 (en) 2015-09-17
WO2014046277A1 (ja) 2014-03-27

Similar Documents

Publication Publication Date Title
CN104661819B (zh) 包装材料以及使用其而成的包装结构
CN103895961B (zh) 包装材料及使用该包装材料的包装结构
CN101658512B (zh) 粘合贴剂
CN1247418C (zh) 透皮药物递送系统的包装体系
KR102378461B1 (ko) 인열 용이성 무연신 수지 필름, 및 그것을 이용한 포장재용 적층 필름
JP2016083421A (ja) 貼付剤入り包装袋、及び貼付剤の保存方法
TW201505665A (zh) 含有利凡斯的明（ｒｉｖａｓｔｉｇｍｉｎｅ）的經皮藥物傳輸系統
CN109476137A (zh) 氧吸收性包装材料
CN107405312A (zh) 经皮吸收剂递送设备及其制造方法
TW202027743A (zh) 含阿申那平貼附劑
CN108348477A (zh) 经皮吸收剂递送设备及其制造方法
CN103347504A (zh) 贴剂及贴剂制剂
WO2021079795A1 (ja) 積層型貼付剤
CN108289888A (zh) 贴剂
JP6746879B2 (ja) シーラントフィルム、多層フィルム、および包装体
CN204585999U (zh) 一种非吸附性、耐药性药用包装复合膜
TWI687230B (zh) 貼附劑用基質及使用其之貼附劑
US20150174279A1 (en) Topical dressing to facilitate wound recovery
JPH03163014A (ja) 貼付剤及びその製造法
CN208552545U (zh) 一种改进型的防滥用阿片类神经麻醉止痛贴片构架
JP2015117241A (ja) 液剤投与用器および液剤投与用器を備えた液型貼付剤
JP2019202965A (ja) セロトニン受容体拮抗薬含有経皮吸収製剤
JP2016202290A (ja) 貼付剤包装体、及び貼付剤の保存方法
JPH0584320U (ja) 粘着製剤の包装構造

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant