CN103976353B - 一种β-胡萝卜素微胶囊的生产方法 - Google Patents
一种β-胡萝卜素微胶囊的生产方法 Download PDFInfo
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- CN103976353B CN103976353B CN201410166381.0A CN201410166381A CN103976353B CN 103976353 B CN103976353 B CN 103976353B CN 201410166381 A CN201410166381 A CN 201410166381A CN 103976353 B CN103976353 B CN 103976353B
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- 235000013734 beta-carotene Nutrition 0.000 title claims abstract description 38
- 239000011648 beta-carotene Substances 0.000 title claims abstract description 38
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 title claims abstract description 35
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 title claims abstract description 35
- 229960002747 betacarotene Drugs 0.000 title claims abstract description 35
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 title claims abstract description 35
- 239000003094 microcapsule Substances 0.000 title claims abstract description 25
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims abstract description 14
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 10
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 10
- 235000006708 antioxidants Nutrition 0.000 claims abstract description 10
- 239000002775 capsule Substances 0.000 claims abstract description 5
- 239000002270 dispersing agent Substances 0.000 claims abstract description 5
- 239000003921 oil Substances 0.000 claims description 18
- 235000019198 oils Nutrition 0.000 claims description 18
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 claims description 16
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000000839 emulsion Substances 0.000 claims description 10
- 239000004250 tert-Butylhydroquinone Substances 0.000 claims description 8
- 235000019281 tert-butylhydroquinone Nutrition 0.000 claims description 8
- 239000007921 spray Substances 0.000 claims description 5
- 239000002285 corn oil Substances 0.000 claims description 4
- 235000005687 corn oil Nutrition 0.000 claims description 4
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 4
- 239000008158 vegetable oil Substances 0.000 claims description 4
- 238000010792 warming Methods 0.000 claims description 4
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims description 3
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-araboascorbic acid Natural products OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- 235000019486 Sunflower oil Nutrition 0.000 claims description 3
- 235000010350 erythorbic acid Nutrition 0.000 claims description 3
- 239000008103 glucose Substances 0.000 claims description 3
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 3
- 235000013824 polyphenols Nutrition 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 239000002600 sunflower oil Substances 0.000 claims description 3
- DINKXUCRJBUQAZ-UHFFFAOYSA-N tert-butyl 5-bromopyridine-3-carboxylate Chemical compound CC(C)(C)OC(=O)C1=CN=CC(Br)=C1 DINKXUCRJBUQAZ-UHFFFAOYSA-N 0.000 claims description 3
- 229940088594 vitamin Drugs 0.000 claims description 3
- 229930003231 vitamin Natural products 0.000 claims description 3
- 235000013343 vitamin Nutrition 0.000 claims description 3
- 239000011782 vitamin Substances 0.000 claims description 3
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- 229920000858 Cyclodextrin Polymers 0.000 claims description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 2
- 229920002774 Maltodextrin Polymers 0.000 claims description 2
- 239000005913 Maltodextrin Substances 0.000 claims description 2
- 235000010489 acacia gum Nutrition 0.000 claims description 2
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims description 2
- 238000007664 blowing Methods 0.000 claims description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 229940035034 maltodextrin Drugs 0.000 claims description 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims description 2
- 239000003549 soybean oil Substances 0.000 claims description 2
- 235000012424 soybean oil Nutrition 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 238000009776 industrial production Methods 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 abstract 2
- 238000005507 spraying Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 5
- 235000013305 food Nutrition 0.000 description 4
- 150000001579 beta-carotenes Chemical class 0.000 description 3
- 235000013373 food additive Nutrition 0.000 description 3
- 239000002778 food additive Substances 0.000 description 3
- 238000004040 coloring Methods 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- -1 moisture Inorganic materials 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 150000002942 palmitic acid derivatives Chemical class 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
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CN201410166381.0A CN103976353B (zh) | 2014-04-24 | 2014-04-24 | 一种β-胡萝卜素微胶囊的生产方法 |
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CN201410166381.0A CN103976353B (zh) | 2014-04-24 | 2014-04-24 | 一种β-胡萝卜素微胶囊的生产方法 |
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CN103976353A CN103976353A (zh) | 2014-08-13 |
CN103976353B true CN103976353B (zh) | 2016-05-11 |
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Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104544069A (zh) * | 2014-12-31 | 2015-04-29 | 无限极(中国)有限公司 | 一种火麻仁油微胶囊的制备方法 |
CN104522666A (zh) * | 2015-01-04 | 2015-04-22 | 吉林省农业科学院 | 一种辅助降血脂的刺玫籽油和紫苏籽油复合微胶囊及其制备方法 |
CN104719894B (zh) * | 2015-03-24 | 2017-07-07 | 武汉志邦化学技术有限公司 | 一种β‑胡萝卜素微胶囊的制备工艺 |
CN105078894A (zh) * | 2015-07-13 | 2015-11-25 | 桂林莱茵生物科技股份有限公司 | 一种水溶性岩藻黄质干粉的制作方法 |
CN105295439B (zh) * | 2015-12-02 | 2017-06-16 | 武汉绿孚生物工程有限责任公司 | 一种微胶囊化栀子黄色素的制备方法 |
CN105639647B (zh) * | 2015-12-31 | 2018-10-12 | 浙江新维普添加剂有限公司 | 一种维生素、类胡萝卜素粉剂及其制备方法和应用 |
CN105595158B (zh) * | 2016-03-01 | 2018-06-15 | 中国农业大学 | 一种具有着色、加香功能的饮料乳剂及其制备方法 |
CN105747216B (zh) * | 2016-03-03 | 2018-11-09 | 广州市食品工业研究所有限公司 | 一种微胶囊β-胡萝卜素粉末及其制备方法 |
CN106617227B (zh) * | 2016-09-09 | 2018-09-18 | 江南大学 | 一种制备β-胡萝卜素微胶囊的方法 |
CN107259506A (zh) * | 2017-06-20 | 2017-10-20 | 武汉星辰现代生物工程有限公司 | 一种β‑胡萝卜素纳米级乳剂的制备工艺及应用 |
CN107827798B (zh) * | 2017-11-21 | 2020-05-08 | 嘉必优生物技术(武汉)股份有限公司 | 一种β-胡萝卜素及其制备方法、应用 |
CN108030063A (zh) * | 2017-12-17 | 2018-05-15 | 江南大学 | 一种高载量高生物利用度的β-胡萝卜素微胶囊的制备方法 |
CN108185424B (zh) * | 2017-12-28 | 2021-08-27 | 大连医诺生物股份有限公司 | 类胡萝卜素微粒制剂及其制备方法 |
CN110477361A (zh) * | 2019-08-26 | 2019-11-22 | 随州市世力达生物科技有限公司 | 一种复配食品添加剂 |
CN110772497A (zh) * | 2019-11-08 | 2020-02-11 | 武汉星辰现代生物工程有限公司 | 一种良好稳定的类胡萝卜素的微囊化方法 |
CN111419821B (zh) * | 2020-04-17 | 2022-08-02 | 万华化学集团股份有限公司 | 一种高全反式类胡萝卜素微胶囊的制备方法 |
CN112471512B (zh) * | 2020-12-13 | 2022-11-08 | 江西师范大学 | 一种高稳定性β-胡萝卜素微胶囊及其制备方法 |
CN112890192A (zh) * | 2021-01-26 | 2021-06-04 | 杭州博可生物科技股份有限公司 | β-胡萝卜素微胶囊化工艺 |
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CN1545923A (zh) * | 2003-12-03 | 2004-11-17 | 广州优宝工业有限公司 | 天然β-胡萝卜素微胶囊及其制备方法 |
CN102198116A (zh) * | 2011-05-30 | 2011-09-28 | 何德海 | 一种维生素a微胶囊的制备方法 |
CN102228257A (zh) * | 2011-06-27 | 2011-11-02 | 湖北福星生物科技有限公司 | 藻油dha微胶囊及其制备方法 |
CN103284290A (zh) * | 2013-05-24 | 2013-09-11 | 肇庆巨元生化有限公司 | 一种良好的类胡萝卜素的微囊化方法 |
CN203492704U (zh) * | 2013-08-21 | 2014-03-26 | 辽宁省食品药品检验所 | 一种新型冷料制浆罐 |
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2014
- 2014-04-24 CN CN201410166381.0A patent/CN103976353B/zh active Active
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CN1545923A (zh) * | 2003-12-03 | 2004-11-17 | 广州优宝工业有限公司 | 天然β-胡萝卜素微胶囊及其制备方法 |
CN102198116A (zh) * | 2011-05-30 | 2011-09-28 | 何德海 | 一种维生素a微胶囊的制备方法 |
CN102228257A (zh) * | 2011-06-27 | 2011-11-02 | 湖北福星生物科技有限公司 | 藻油dha微胶囊及其制备方法 |
CN103284290A (zh) * | 2013-05-24 | 2013-09-11 | 肇庆巨元生化有限公司 | 一种良好的类胡萝卜素的微囊化方法 |
CN203492704U (zh) * | 2013-08-21 | 2014-03-26 | 辽宁省食品药品检验所 | 一种新型冷料制浆罐 |
Non-Patent Citations (1)
Title |
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几种β-胡萝卜素微胶囊干粉的压缩特性和成型机理;许新德等;《化工学报》;20070228;第58卷(第2期);452-459 * |
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