CN103221047B - 化合物和方法 - Google Patents

化合物和方法 Download PDF

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Publication number
CN103221047B
CN103221047B CN201180013827.0A CN201180013827A CN103221047B CN 103221047 B CN103221047 B CN 103221047B CN 201180013827 A CN201180013827 A CN 201180013827A CN 103221047 B CN103221047 B CN 103221047B
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Prior art keywords
trifluoromethyl
oxadiazol
methyl
alkyl
benzamide
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Expired - Fee Related
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CN201180013827.0A
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Chinese (zh)
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CN103221047A (zh
Inventor
E.巴洛格鲁
S.戈什
M.洛贝拉
D.施密特
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Tempero Pharmaceuticals Inc
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Tempero Pharmaceuticals Inc
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Neurology (AREA)
  • Hematology (AREA)
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  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
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  • Child & Adolescent Psychology (AREA)
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CN201180013827.0A 2010-01-13 2011-01-13 化合物和方法 Expired - Fee Related CN103221047B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29457510P 2010-01-13 2010-01-13
US61/294,575 2010-01-13
PCT/US2011/021089 WO2011088181A1 (en) 2010-01-13 2011-01-13 Compounds and methods

Publications (2)

Publication Number Publication Date
CN103221047A CN103221047A (zh) 2013-07-24
CN103221047B true CN103221047B (zh) 2014-12-17

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US (2) US8901156B2 (enExample)
EP (1) EP2533783B8 (enExample)
JP (1) JP6017313B2 (enExample)
KR (1) KR101781663B1 (enExample)
CN (1) CN103221047B (enExample)
AU (1) AU2011205283B2 (enExample)
BR (1) BR112012017441B1 (enExample)
CA (1) CA2787018A1 (enExample)
EA (1) EA022964B1 (enExample)
ES (1) ES2560627T3 (enExample)
IL (1) IL220939A (enExample)
MX (1) MX341133B (enExample)
SG (1) SG182401A1 (enExample)
WO (1) WO2011088181A1 (enExample)
ZA (1) ZA201205125B (enExample)

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