CN103201261A - 用作为食欲素受体拮抗剂的内酰胺衍生物 - Google Patents

用作为食欲素受体拮抗剂的内酰胺衍生物 Download PDF

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Publication number
CN103201261A
CN103201261A CN2011800543642A CN201180054364A CN103201261A CN 103201261 A CN103201261 A CN 103201261A CN 2011800543642 A CN2011800543642 A CN 2011800543642A CN 201180054364 A CN201180054364 A CN 201180054364A CN 103201261 A CN103201261 A CN 103201261A
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dimethoxyphenyl
benzyl
methyl
piperidin
pyrrolidin
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CN2011800543642A
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Chinese (zh)
Inventor
哈马德·艾斯奥维
克里斯多夫·博斯
克莉丝汀·普罗奇
比比安·海德曼
蒂埃里·西弗朗
约迪·T·威廉斯
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Actelion Pharmaceuticals Ltd
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Actelion Pharmaceuticals Ltd
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Publication of CN103201261A publication Critical patent/CN103201261A/zh
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Epidemiology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
CN2011800543642A 2010-11-10 2011-11-09 用作为食欲素受体拮抗剂的内酰胺衍生物 Pending CN103201261A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IBPCT/IB2010/055105 2010-11-10
IB2010055105 2010-11-10
PCT/IB2011/054993 WO2012063207A1 (en) 2010-11-10 2011-11-09 Lactam derivatives useful as orexin receptor antagonists

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CN103201261A true CN103201261A (zh) 2013-07-10

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US (1) US9242970B2 (enExample)
EP (1) EP2638008B1 (enExample)
JP (1) JP5847830B2 (enExample)
CN (1) CN103201261A (enExample)
CA (1) CA2815179A1 (enExample)
WO (1) WO2012063207A1 (enExample)

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CN104133004A (zh) * 2013-05-03 2014-11-05 上海美迪西生物医药有限公司 血浆样品中2,3-吲哚醌的浓度的测定方法
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UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
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