CN102746299A - 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途 - Google Patents

8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途 Download PDF

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Publication number
CN102746299A
CN102746299A CN201210245827XA CN201210245827A CN102746299A CN 102746299 A CN102746299 A CN 102746299A CN 201210245827X A CN201210245827X A CN 201210245827XA CN 201210245827 A CN201210245827 A CN 201210245827A CN 102746299 A CN102746299 A CN 102746299A
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alkyl
radical
hydrogen
optionally substituted
aryl
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Chinese (zh)
Inventor
詹姆斯.F.卡拉汉
杰弗里.C.贝姆
安东尼.W.J.库珀
斯蒂法诺.利维娅
尼萨.内文斯
万泽红
贝丝.A.诺顿
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Glaxo Group Ltd
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Glaxo Group Ltd
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    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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CN201210245827XA 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途 Pending CN102746299A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66531505P 2005-03-25 2005-03-25
US60/665,315 2005-03-25

Related Parent Applications (1)

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CNA2006800182268A Division CN101258148A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途

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Publication Number Publication Date
CN102746299A true CN102746299A (zh) 2012-10-24

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Application Number Title Priority Date Filing Date
CNA2006800182268A Pending CN101258148A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途
CN2012102458960A Pending CN102746301A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途
CN201210245827XA Pending CN102746299A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途
CN2012102458299A Pending CN102746300A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途

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Application Number Title Priority Date Filing Date
CNA2006800182268A Pending CN101258148A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途
CN2012102458960A Pending CN102746301A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途

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Application Number Title Priority Date Filing Date
CN2012102458299A Pending CN102746300A (zh) 2005-03-25 2006-03-24 8-苯基-7,8-二氢吡啶并[2,3-d]嘧啶-7-酮及其作为药物的用途

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Country Link
US (3) US7678801B2 (de)
EP (3) EP1868611B1 (de)
JP (1) JP5037487B2 (de)
KR (1) KR101235497B1 (de)
CN (4) CN101258148A (de)
AR (1) AR053346A1 (de)
AU (1) AU2006229993B2 (de)
BR (1) BRPI0609437A2 (de)
CA (1) CA2602553C (de)
EA (1) EA012875B1 (de)
ES (2) ES2426251T3 (de)
HK (1) HK1111422A1 (de)
IL (1) IL185870A (de)
MA (1) MA29341B1 (de)
MX (1) MX2007011856A (de)
MY (2) MY145343A (de)
NO (1) NO20075275L (de)
NZ (1) NZ561237A (de)
PE (2) PE20100737A1 (de)
SG (1) SG166771A1 (de)
TW (1) TWI389690B (de)
UA (1) UA95444C2 (de)
UY (1) UY29440A1 (de)
WO (1) WO2006104915A2 (de)
ZA (1) ZA200707564B (de)

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ME02908B (de) * 2011-08-25 2018-10-20 Medicines For Malaria Venture Mmv Substituierte 2-alkyl-1-oxo-n-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisochinolin-4-carboxamide für antimalaria-therapien
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Application publication date: 20121024