CN102223847A - 用于操纵导管轴的装置和方法 - Google Patents

用于操纵导管轴的装置和方法 Download PDF

Info

Publication number
CN102223847A
CN102223847A CN2009801464405A CN200980146440A CN102223847A CN 102223847 A CN102223847 A CN 102223847A CN 2009801464405 A CN2009801464405 A CN 2009801464405A CN 200980146440 A CN200980146440 A CN 200980146440A CN 102223847 A CN102223847 A CN 102223847A
Authority
CN
China
Prior art keywords
elongated tubular
tubular shafts
hinge components
bending section
distal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2009801464405A
Other languages
English (en)
Other versions
CN102223847B (zh
Inventor
D·杜德
T·胡列夫
R·迈克纳尔
B·费尔
P·古普塔
R·奥利维拉
T·彭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Tyco Healthcare Group LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tyco Healthcare Group LP filed Critical Tyco Healthcare Group LP
Publication of CN102223847A publication Critical patent/CN102223847A/zh
Application granted granted Critical
Publication of CN102223847B publication Critical patent/CN102223847B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A61M25/0014—Connecting a tube to a hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0097—Catheters; Hollow probes characterised by the hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133—Tip steering devices
    • A61M25/0152—Tip steering devices with pre-shaped mechanisms, e.g. pre-shaped stylets or pre-shaped outer tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00318—Steering mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00318—Steering mechanisms
    • A61B2017/00331—Steering mechanisms with preformed bends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • A61B2017/00389—Button or wheel for performing multiple functions, e.g. rotation of shaft and end effector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046—Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • A61B2017/00469—Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable for insertion of instruments, e.g. guide wire, optical fibre
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00778—Operations on blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
    • A61B2017/320791—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter with cutter extending outside the cutting window
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133—Tip steering devices
    • A61M2025/0161—Tip steering devices wherein the distal tips have two or more deflection regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1066—Tube connectors; Tube couplings having protection means, e.g. sliding sleeve to protect connector itself, shrouds to protect a needle present in the connector, protective housing, isolating sheath

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

一种用于在血管的内腔中的治疗部位处执行手术的导管。导管包括细长的管状轴，该细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件。轴的远端部分包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过轴的侧壁。工作元件布置在细长的管状轴的内腔内，并构造成用于穿过窗在治疗部位处执行手术。弯曲部和铰链元件构造成在治疗部位处将窗推靠在血管壁上。

Description

用于操纵导管轴的装置和方法
相关申请的交叉参考
本申请要求享有2008年12月15日提交的临时申请No.61/122,601和2008年10月13日提交的临时申请No.61/104,836的优先权。这些临时申请的整个内容由此通过参考包含于此。
背景技术
粥样斑块切除(Atherectomy)导管用于从血管去除材料以打开血管的内腔并且提高通过血管的血流量。
粥样斑块切除导管通常具有定位在导管的远端处或附近的切除器。某些粥样斑块切除导管设计成仅沿着其远端周边的一部分切除。这种“定向粥样斑块切除”导管必须被操纵成使得切除器定位在待切除的材料附近。这种操纵可以包括将切除器推靠在血管的一侧上，以便可以切除材料，并且这种操纵可以包括转动导管轴的近端区域，从而使导管的远端区域转动，并由此将位于远端的定向切除器定位在待切除的材料附近。
本发明涉及用于操纵和推动粥样斑块切除导管的切除元件以使切除器定位在待切除的材料附近的装置和方法。
发明内容
本发明提供一种操纵器，所述操纵器与粥样斑块切除导管一起使用来转动、平移、或者转动和平移导管。粥样斑块切除导管可以具有切除元件，所述切除元件能够通过窗伸出以切除感兴趣的材料。可以仅用一只手致动该操纵器。
在本发明的另一个方面中，粥样斑块切除导管设有预形成的远端区域。预形成的远端区域推动粥样斑块切除导管切除器以强迫其与血管的内壁接触。当切除元件遇到组织时，通过导管的预形成的远端区域抵抗趋向于使切除元件从组织偏离开的力。
在一个方面中，本发明涉及一种用于在血管的内腔中的治疗部位处执行手术的导管，血管在治疗部位处具有直径D。导管包括细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，近端弯曲部限定大于零的第一角，远端弯曲部限定大于第一角的第二角，铰链元件从细长的管状轴的远端向近端侧间隔开并且从远端弯曲部向远端侧间隔开，远端弯曲部定位在近端弯曲部和铰链元件之间，细长的管状轴的远端部分在铰链元件和细长的管状轴的远端之间延伸，并且细长的管状轴的中间部分在铰链元件和近端弯曲部之间延伸，远端部分包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过侧壁。导管还包括工作元件，所述工作元件布置在细长的管状轴的内腔内，工作元件构造成用于穿过窗在治疗部位处执行手术，第一角和第二角选择成形成细长的管状轴在近端弯曲部和铰链元件之间、大于直径D的最大偏移，以便使窗被推靠在治疗部位处的血管壁上。近端弯曲部和远端弯曲部可以构造成位于第一平面内，并且铰链元件可以构造成仅在第一平面内允许远端部分相对于中间部分弯曲。第一角和第二角可以选择成以在约0.05磅至0.5磅的范围内的力将窗推靠在血管壁上。第一角可以处于约90°至150°的范围内，并且第二角可以处于约100°至180°的范围内。从近端弯曲部到远端弯曲部的长度可以大于从远端弯曲部到铰链元件的长度。远端弯曲部和近端弯曲部之间的长度可以处于约0.5英寸至2.0英寸的范围内，并且远端弯曲部和铰链元件之间的长度可以处于约0.375英寸至0.625英寸的范围内。最大偏移可以处于约3毫米至40毫米的范围内。
在另一个方面中，本发明涉及一种用于在血管的内腔中的治疗部位处执行手术的导管。导管包括细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有曲线状的远端部分，所述曲线状的远端部分具有连续减小的曲率半径，连续减小的曲率半径在第一平面内从远端部分的近端到细长的管状轴的远端定向，远端部分包括铰链元件，所述铰链元件与细长的管状轴的远端向近端地间隔开，铰链元件将远端部分分成在铰链元件和细长的管状轴的远端之间的远端分段以及在铰链元件和远端部分的近端之间的近端分段，铰链元件构造成仅在第一平面内允许远端分段相对于近端分段弯曲，远端分段包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过侧壁。导管还包括工作元件，所述工作元件布置在细长的管状轴的内腔内，工作元件构造成用于穿过窗在治疗部位处执行手术，连续减小的曲率半径选择成在使用期间将窗推靠在治疗部位处的血管壁上。曲线状的远端部分可以形成在约90°至720°的范围内的连续的曲线。曲线状的远端部分的最大曲线直径可以处于约3毫米至50毫米的范围内。
在又一个方面中，本发明涉及一种在血管的内腔中的治疗部位处执行手术的方法。该方法包括提供细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，近端弯曲部限定大于零的第一角，远端弯曲部限定大于第一角的第二角，近端弯曲部和远端弯曲部沿着第一方向定向，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开并且从所述远端弯曲部向远端侧间隔开，远端弯曲部定位在近端弯曲部和铰链元件之间，细长的管状轴的远端部分在铰链元件和细长的管状轴的远端之间延伸，并且细长的管状轴的中间部分在铰链元件和近端弯曲部之间延伸，远端部分包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过侧壁。该方法还包括：将细长的管状轴通过血管的内腔前进到治疗部位；将细长的管状轴定向在这样的位置中，即，在所述位置处近端弯曲部和远端弯曲部使细长的管状轴的远端部分在铰链元件处沿着与第一方向相反的第二方向相对于细长的管状轴的中间部分弯曲以在所述治疗部位处的期望的位置中将所述窗推靠在血管壁上；以及在将所述窗推靠在所述血管壁上的同时，借助布置在所述细长的管状轴的内腔内的工作元件在所述治疗部位处穿过所述窗执行手术。铰链元件可以构造成仅沿着第一方向和第二方向允许远端部分相对于中间部分弯曲。
在又一个方面中，本发明涉及一种在血管的内腔中的治疗部位处执行手术的方法，该方法包括提供细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有曲线状的远端部分，所述曲线状的远端部分具有连续减小的曲率半径，连续减小的曲率半径沿着第一方向从远端部分的近端到细长的管状轴的远端定向，远端部分包括铰链元件，所述铰链元件从细长的管状轴的远端向近端侧间隔开，铰链元件将远端部分分成在铰链元件和细长的管状轴的远端之间的远端分段以及在铰链元件和远端部分的近端之间的近端分段，铰链元件构造成仅沿着第一方向和与第一方向相反的第二方向允许远端分段相对于近端分段弯曲，远端分段包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过侧壁。该方法还包括：将细长的管状轴通过血管的内腔前进到治疗部位；将细长的管状轴定向在这样的位置中，即，在所述位置处曲线状的远端部分的连续减小的曲率半径使远端分段在铰链元件处沿着第二方向相对于近端分段弯曲以在所述治疗部位处的期望的位置中将所述窗推靠在血管壁上；以及在将所述窗推靠在所述血管壁上的同时借助布置在所述细长的管状轴的内腔内的工作元件在所述治疗部位处穿过所述窗执行手术。
在又一个方面中，本发明涉及一种用于操纵导管的轴的装置，所述导管包括本体部分和轴接合构件，所述本体部分具有内腔，所述内腔的尺寸设定成接收导管的轴，所述轴接合构件具有封闭在本体部分内的第一轴接合面和第二轴接合面，轴接合构件具有锁定位置和解锁位置，在所述锁定位置中第一轴接合面和第二轴接合面构造成接合轴以将本体锁定在轴上，在所述解锁位置中本体自由转动并在细长的管状轴上轴向地平移。轴接合面可以在锁定位置或解锁位置中被偏压。
在又一个方面中，本发明涉及一种用于接近血管壁上的部位的导管。导管包括细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有第一弯曲部、第二弯曲部和窗，所述第二弯曲部与第一弯曲部向远端地间隔开了预定的距离，所述窗延伸通过侧壁，所述窗定位在所述第二弯曲部的远端侧并且在所述细长的管状构件的远端的近端侧，第一弯曲部限定大于零的第一角，第二弯曲部限定大于第一角的第二角，第一角和第二角以及预定的距离选择成在使用期间将窗推靠在血管壁上的部位上。细长的管状轴还可以包括铰链元件，所述铰链元件从窗向近端侧间隔开并且从第二弯曲部向远端侧间隔开。另外，导管可以包括工作元件，所述工作元件布置在细长的管状轴的内腔内，工作元件构造成用于穿过窗在血管壁上的部位处执行手术。细长的管状轴可以包括在铰链元件和细长的管状轴的远端之间的远端部分，并且铰链元件可以构造为远端部分围绕其弯曲的枢转点。另外，远端部分可以具有纵向轴线，并且铰链元件可以构造成使得当在使用期间将窗推靠在血管壁上的部位上时，远端部分定位成使得远端部分的纵向轴线基本上与血管的纵向轴线平行。
在又一个方面中，本发明涉及一种用于在血管的内腔中的治疗部位处执行手术的导管，所述导管包括细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，近端弯曲部限定大于零的第一角，远端弯曲部限定大于第一角的第二角，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开并且从所述远端弯曲部向远端侧间隔开，远端弯曲部定位在近端弯曲部和铰链元件之间，细长的管状轴的远端部分在铰链元件和细长的管状轴的远端之间延伸，并且细长的管状轴的中间部分在铰链元件和近端弯曲部之间延伸，远端部分包括窗，所述窗在铰链元件和细长的管状轴的远端之间延伸穿过侧壁，近端弯曲部、远端弯曲部和铰链元件构造成在治疗部位处将窗推靠在血管壁上。导管可以包括工作元件，所述工作元件布置在细长的管状轴的内腔内，工作元件构造成用于当在使用期间将窗推靠在血管壁上时穿过窗在治疗部位处执行手术。
本发明的这些和其它方面将从以下优选实施例的说明、附图和权利要求而变得清楚。参照附图和以下说明阐述本发明的一个或多个实施例的细节。本发明的其它特征、目标和优点将从说明和附图以及从权利要求而变得清楚。
附图说明
图1A示出根据本发明的原理的轴操纵器的一个实施例的示意性平面图；
图1B示出图1A中所示的轴操纵器的立体图；
图1C和1D示出沿着图1A中所示的轴操纵器的线A-A得到的剖视图；
图2A示出根据本发明的原理的轴操纵器的另一个实施例的示意性平面图；
图2B示出图2A中所示的轴操纵器的立体图；
图2C和2D示出沿着图2A中所示的轴操纵器的线A-A得到的剖视图；
图3A和3B示出根据本发明的原理的轴操纵器的又一个实施例的示意性平面图；
图4A和4B示出根据本发明的原理的导管的又一个实施例的示意性平面图；
图5A至5C示出根据本发明的原理的导管的又一个实施例的示意性平面图。
具体实施方式
参照图1A至1D的实施例，本发明涉及一种用于操纵导管轴的装置。结合粥样斑块切除导管说明本发明，但是本发明可以与任何其它导管一起使用。
粥样斑块切除导管20具有工作元件22，例如切除元件。切除元件可以通过导管的轴26中的窗24延伸。可以理解，工作元件可以是任何其它元件，例如RF元件、可视化元件或植入输送元件。典型地，导管20可以具有3Fr至7Fr的工作直径并且具有60cm至180cm的工作长度。
可以通过转动轴26操纵工作元件22的定向，以便使手柄28可以在轴转动的同时保持固定。轴会可按增量转动或者可调节到任何角度定向。在某些实施例中，轴联接到手柄，以在对轴施加适度的转矩时允许轴相对于手柄转动。在其它实施例中，轴可转动地固定到手柄，以在对轴施加适度的转矩时不允许轴相对于手柄转动。
轴操纵器10可转动地且可滑动地联接到轴26，并且该轴操纵器构造成用一只手使用。操纵器10包括本体12、按钮14、弹簧16和枢转销18，所述本体具有内腔11。按钮14还包括臂14c，该臂中具有用于使枢转销可滑动地配合通过的孔。本体12和按钮14可以由聚碳酸酯、尼龙或其它材料制成，并且可以被注射模制或以其它方式制造成期望的构造。本体12可以模制成两个半部分，并且在按钮、枢转销和弹簧组装到本体中之后，这两个半部分通过超声波、咬合配合、粘结剂、或其它装置结合在一起。在一个实施例中，通过图1B中的线A-A限定本体12的两个半部分。按钮14的面14a、14b可以是有纹理的，以用于增大抵抗轴26或操作者的手指或二者的摩擦。弹簧16和枢转销18可以包括诸如钢、弹簧钢、或其它金属的金属，或者诸如聚酯、液晶聚合物、尼龙或其它聚合物的工程聚合物。
操纵器10通常处于解锁(图1C)位置中，其中弹簧16伸展以迫使按钮14的面14a远离轴26。操纵器通常被解锁以允许使用者容易将操纵器10移动到沿着轴的任何期望的位置。例如，使用者可以在用一只手保持手柄28的同时用另一只手将操纵器移动到轴的暴露的远端部分，例如在切口附近或在导引器护套附近的轴的一部分。一旦操纵器定位在沿着轴的期望的位置处，则可以通过在使用者用一只手将按钮14的面14b朝向彼此加压并随后用同一只手转动或平移(或二者)操纵器10而实现轴26的转动或平移(或二者)。
现在说明图1A至1D的导管和操纵器的用法。导管20以任何已知的方式引入到患者体内。当使用者期望操纵导管时，使用者抓紧操纵器10并将其移动到用于操纵导管的适当的位置。然后，使用者通过在面14b上施压以克服弹簧16的力并将面14a移动到与轴26摩擦接触，而将操纵器锁定到轴。然后，操纵器被转动、平移、或转动和平移二者以实现与诸如粥样斑块(atheroma)的组织接触的切除器22的转动、平移、或转动和平移二者。在某些实施例中，切除器22沿着径向方向延伸到窗24之外，并且在切除器22延伸以切除粥样斑块的情况下导管20穿过血管前进。在某些实施例中，粥样斑块由切除器22导引到导管的内部。
已经说明了轴操纵器处于常解锁位置中，然而，在其它实施例中，轴操纵器可以处于常锁定位置中，从而使用者将压力施加在卡爪上以打开卡爪而不是关闭卡爪。图2A至2D示出构造成处于常锁定位置中的轴操纵器30。操纵器30可转动地且可滑动地联接到轴26，并且轴操纵器30构造成用一只手使用。操纵器30包括本体32、臂34、弹簧36和枢转销38，所述本体具有内腔31。臂34中具有用于使枢转销可滑动地配合通过的孔，臂34具有面34a并且具有可以被扩大的端部34b。本体32、臂34、面34a、弹簧36和枢转销38可以基本上分别与上述本体12、按钮14、面14a、弹簧16和枢转销18一样由材料制成、制造并且组装。
操纵器30通常处于锁定(图2C)位置中，其中弹簧36伸展以迫使臂34的面34a与轴26摩擦接触。操纵器通常锁定以允许使用者容易转动或平移(或二者)轴26。使用者可以通过将臂34b朝向彼此加压以迫使面34a脱离与轴26的接触(图2D)，并随后在轴26上转动或平移(或二者)操纵器30，而用一只手将操纵器30移动到沿着轴26的任何期望的位置。例如，使用者可以将操纵器移动到轴的暴露的远端部分，例如在切口附近或在导引器护套附近的轴的一部分。使用这种操纵器的优点在于，操纵器可以容易地沿着轴定位并且在用一只手保持手柄28的同时用另一只手操纵。
现在说明图2A至2D的导管和操纵器的用法。导管20以任何已知的方式引入到患者体内。当使用者期望操纵导管时，使用者抓紧操纵器30，并且通过在端部34b上施压以使面34a移动脱离与轴26的摩擦接触，而将操纵器从轴解锁。然后，使用者将操纵器30移动到用于操纵导管的适当的位置。然后，去除端部34b上的压力，从而允许弹簧36将面34a移动成与轴26摩擦接触。然后，操纵器被转动、平移、或转动和平移二者，以实现与诸如粥样斑块的组织接触的切除器22的转动、平移、或转动和平移二者。在某些实施例中，切除器22沿着径向方向延伸到窗24之外，并且在切除器22延伸以切除粥样斑块的情况下导管20穿过血管前进。在某些实施例中，粥样斑块由切除器22导引到导管的内部。
参照图3A和3B的实施例，示出用于与操纵器45一起使用的另一个导管40。导管40可以与上述的导管20类似，但是可以是具有工作元件、具有与上述的轴26类似的轴26或另外的轴的任何其它的导管，并且无论如何都添加有环部42。操纵器45可以包括上述的操纵器10、30，或者可以是另外的操纵器。手柄48可以与上述的手柄28类似，但是可以是任何其它的手柄。
导管40包括轴46，所述轴具有定位在操纵器和手柄之间的环部42。环部42可以由柔性的导管部分形成并且当形成时包括间隙44，该导管部分设计成在操纵轴时形成为环部或者可以是预形成的环形导管部分。轴46固定地联接到手柄48，以便使轴相对于手柄不会转动或平移。当操纵器45转动或平移时，环部42具有充分的柔性以在不需要手柄的方位或位置改变的情况下允许轴的远端部分被操纵器转动或平移。在轴46相对于手柄48转动或平移的过程中，环部42的直径47可以变大或变小，并且间隙44可以增大或减小，以在允许手柄48保持处于不变的位置中的同时适应轴46的转动或平移。
现在说明图3A和3B的导管的用法。导管以任何已知的方式引入到患者体内。当使用者期望操纵导管时，使用者抓紧操纵器并且将操纵器移动到用于操纵导管的适当的位置。然后，使用者将操纵器锁定到轴上。随着轴被操纵，环部将根据需要而压缩、膨胀或改变间隙，以在手柄位置保持不变的同时适应轴的转动、平移、或转动和平移二者。在某些实施例中，切除器22沿着径向方向延伸到窗24之外，并且在切除器22延伸以切除粥样斑块的情况下导管20穿过血管前进。在某些实施例中，粥样斑块由切除器22导引到导管的内部。
图4A和4B示出用于与操纵器55一起使用的另一个导管50。轴的远端部分的形状设定成提供附着力以将切除元件推靠在血管壁上。导管50可以与上述的导管20类似，但是可以是具有工作元件、具有与上述的轴26类似的轴56或另外的轴的任何其它的导管，并且无论如何都添加有转向部(jog)51j和预形成的弯曲部51p、51d。导管50还包括可以在构造、材料和功能方面分别与工作元件22和窗24类似的工作元件52和窗54。窗54定位在轴上的径向内部位置处，以便当导管定位在血管内时工作元件52被推靠在血管壁上。转向部51j和预形成的弯曲部51p、51d协同操作以推动工作元件52与血管中的待切除的材料接触。操纵器55可以包括上述的操纵器10、30或者可以是另外的操纵器。具有导管50的操纵器55的用法是任选的。手柄58可以与上述的手柄28类似，但是可以是任何其它的手柄。
导管轴56包括转向部51j和预形成的弯曲部51p、51d。转向部51j包括铰链结构，所述铰链结构允许轴56的远端部分56d相对于轴56的中间部分56m急剧地弯曲。在2004年7月21日提交的、公布为US 2005/0177068A1的美国专利申请10/896,741的段落[0092]至[0094]、[0100]至[0102]、[0105]至[0107]和附图1、1A、2、4A和4B中进一步说明了能够转向的导管结构。US专利公布US 2005/0177068的整个内容由此通过参考包含于此。在一个实施例中，预形成的弯曲部形成为使得中间部分以及在中间部分的近端处的导管轴的部分位于第一平面内，并且铰链元件构造成仅在第一平面内允许远端部分相对于中间部分弯曲。预形成的弯曲部51p、51d可以通过在将远端部分56d约束在金属模具中之后施加热而形成，以便使导管56具有模具的形状，或者可以通过对于本领域的技术人员已知的其它手段来形成。预形成的弯曲部51p的角53p小于预形成的弯曲部51d的角53d。预形成的弯曲部51p可以具有90度至150度的角。在一个实施例中，预形成的弯曲部51p具有100度至120度的角。在其它实施例中，角53p是95度、105度、110度、115度、125度、130度或140度。预形成的弯曲部51d可以具有100度至180度的角。在一个实施例中，预形成的弯曲部51d具有120度至140度的角。在其它实施例中，角53d是110度、130度、150度、160或170度。从预形成的弯曲部51p到预形成的弯曲部51d的长度通常大于从预形成的弯曲部51d到转向部51j的长度。从预形成的弯曲部51p到预形成的弯曲部51d的长度可以是0.5英寸到2.0英寸。在一个实施例中，从预形成的弯曲部51p到预形成的弯曲部51d的长度是1.00英寸到1.25英寸。在其它实施例中，从预形成的弯曲部51p到预形成的弯曲部51d的长度是0.75英寸、1.5英寸或1.75英寸。从预形成的弯曲部51d到转向部51j的长度可以是0.125英寸到1.0英寸。在一个实施例中，从预形成的弯曲部51d到转向部51j的长度是0.375英寸到0.625英寸。在某些实施例中，从预形成的弯曲部51d到转向部51j的长度是0.25英寸、0.5英寸、0.75英寸或0.875英寸。组合的弯曲部51p、51d和这些弯曲部之间的长度以及弯曲部和转向部之间的长度使导管56从导管56的未弯曲部分至转向部56j具有最大偏移56e。通常，本发明的导管选择成使其偏移大于将使用导管50的血管或管道的直径。偏移56e可以是3毫米至40毫米。在一个实施例中，偏移56e是5毫米至8毫米。在某些实施例中，偏移56e是4毫米、5毫米、6毫米、7毫米、8毫米、10毫米、12毫米、15毫米、20毫米、25毫米、30毫米或35毫米。
当导管50定位在直径D小于未受约束的偏移56e的血管V内时，迫使预形成的弯曲部51p和51d以在转向部51j允许导管50的最远端部分沿着血管V的内壁定向的同时，预形成的弯曲部所呈现的角大于其不偏离的预形成的角。由于预形成的弯曲部企图恢复其不偏离的预形成的角，转向部51j和弯曲部51p、51d之间的协同操作迫使或推动窗54以与血管V的内壁接触。预形成的弯曲部51d维持切除器52和窗54在血管直径的下端部处抵抗血管V的内壁的附着力。随着血管直径增大，预形成的弯曲部51p最终也开始向导管尖端施加附着力。推力可以为0.05磅至0.5磅。在一个实施例中，推力是0.1磅。在某些实施例中，推力是0.075磅、0.2磅、0.3磅或0.4磅。诸如切除器的工作元件52可以通过窗54延伸以接触诸如粥样斑块的待切除的材料。在切除过程中，将通过如上所述产生的推力抵抗趋向于使切除器从血管内表面偏离开的力。轴56的远端部分可以通过操纵器55(如果使用的话)转动、平移、或转动和平移二者以确保窗54沿周向定向成接触待切除的材料。
现在说明图4A和4B的导管的用法。选择具有大于血管V的内径的偏移56e的导管50。任选地，导管以任何已知的方式在导丝上引入到患者体内到达待去除材料的血管V中的位置。导管在导丝上引入时趋向于略微伸直并且跟随导丝到达该位置。与转向部51j协同操作的预形成的弯曲部51p、51d将窗54推靠在血管V的内壁上。在某些实施例中，切除器52沿着径向方向延伸到窗54之外，并且在切除器52延伸以切除粥样斑块的情况下导管50穿过血管前进。在某些实施例中，粥样斑块由切除器52导引到导管的内部。任选地，当使用者期望操纵导管时，使用者抓紧操纵器55并且将操纵器55移动到用于操纵导管的适当的位置。然后，使用者将操纵器锁定到轴56上并且在手柄58的位置保持不变的同时转动、平移、或转动和平移轴。
图5A至5C示出用于与操纵器65一起使用的另一个导管60。轴的远端部分的形状设定成提供附着力以将切除元件推靠在血管壁上。导管60可以与上述的导管20类似，但是可以是具有工作元件、具有与上述的轴26类似的轴66或另外的轴的任何其它的导管，无论如何都添加有转向部61j和连续减小半径的曲线部61。转向部61j在构造、材料和功能方面可以与转向部51j类似。导管60还包括可以在构造、材料和功能方面分别与工作元件22和窗24类似的工作元件62和窗64。工作元件62定位在轴上的径向内部位置处，以便当导管定位在血管内时工作元件62被推靠在血管壁上。转向部61j和连续减小半径的曲线部61协同操作以推动工作元件62与血管中的待切除的材料接触。操纵器65可以包括上述的操纵器10、30或者可以是另外的操纵器。操纵器65与导管60的用法是任选的。手柄68可以与上述的手柄28类似，但是可以是任何其它的手柄。
导管轴66包括转向部61j和连续减小半径的曲线部61。连续减小半径的曲线部61可以通过在将导管轴66的远端部分66d约束在金属模具中之后施加热而形成，以便使远端部分66d具有模具的形状，或者可以通过对于本领域的技术人员已知的其它手段来形成。远端部分66d可以卷曲约至少90度直到至少720度。图5A示出卷曲约360度的轴，并且图5B示出卷曲约720度的轴。在其它实施例中，远端部分66d卷曲约120度、150度、180度、240度、300度、480度或600度。最大曲线直径63可以从3毫米到50毫米变化，虽然依据具体应用最大曲线直径可以在该范围以外。在一个实施例中，最大曲线直径是10毫米至12毫米。在其它实施例中，最大曲线直径是4毫米、6毫米、8毫米、15毫米、20毫米、25毫米、30毫米或40毫米。
在另一个实施例中，连续减小半径的曲线部61可以包括多个离散的预形成的弯曲部(未示出)。可以理解，减小半径的段的数量可以变化。例如，导管可以具有从2个到100个段。在其它实施例中，导管可以具有4个、6个、8个、10个、15个、20个、40个、60个、75个或100个段。在另外的实施例中，导管具有如图5A至5C的连续可变的实施例中所公开的无限数量的段。
连续减小的半径用于在血管直径的范围上提供相对均匀的附着力。当然，由于不同患者的血管几何结构和尺寸会有相当大的变化，所以实际的附着力可以在使用期间相当大地变化；然而，轴的形状趋向于在血管尺寸的范围上提供均匀的力。
当导管60定位在直径D小于最大曲线直径63的血管V内时，在转向部61j允许导管60的最远端部分沿着血管V的内壁定向的同时迫使连续减小半径的曲线部61的直径增大。由于曲线部61企图恢复其未变形的直径，所以转向部56j和曲线部61之间的协同操作会迫使或推动窗64以与血管V的内壁接触。诸如切除器的工作元件62可以通过窗64延伸以接触诸如粥样斑块的待切除的材料。在切除过程中，将通过如上所述产生的推力抵抗趋向于使切除器从血管内表面偏离开的切除力。轴66的远端部分可以通过操纵器65(如果使用的话)转动、平移、或转动和平移二者以确保窗64沿周向定向成接触待切除的材料。
现在说明图5A至5C的导管的用法。导管以任何已知的方式在导丝上引入到患者体内到达待去除材料的位置。导管在导丝上引入时趋向于略微伸直并且跟随导丝到达该位置。与转向部61j协同操作的曲线部61将窗64推靠在血管V的内壁上。在某些实施例中，切除器62沿着径向方向延伸到窗64之外，并且在切除器62延伸以切除粥样斑块的情况下导管60穿过血管前进。在某些实施例中，粥样斑块由切除器62导引到导管的内部。任选地，当使用者期望操纵导管时，使用者抓紧操纵器65并且将操纵器65移动到用于操纵导管的适当的位置。然后，使用者将操纵器锁定到轴66上并且在手柄68的位置保持不变的同时转动、平移、或转动和平移轴。
已经参照优选的实施例说明本发明，但是当然可以在脱离上述的说明性的实施例的情况下实施本发明。

Claims (52)

1.一种用于在血管的内腔中的治疗部位处执行手术的导管，所述血管在所述治疗部位处具有直径D，所述导管包括：
细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，所述细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，所述近端弯曲部限定大于零的第一角，所述远端弯曲部限定大于所述第一角的第二角，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开并且从所述远端弯曲部向远端侧间隔开，所述远端弯曲部定位在所述近端弯曲部和所述铰链元件之间，所述细长的管状轴的远端部分在所述铰链元件和所述细长的管状轴的远端之间延伸，并且所述细长的管状轴的中间部分在所述铰链元件和所述近端弯曲部之间延伸，所述远端部分包括窗，所述窗在所述铰链元件和所述细长的管状轴的远端之间延伸穿过所述侧壁；和
工作元件，所述工作元件布置在所述细长的管状轴的内腔内，所述工作元件构造成用于通过窗在所述治疗部位处执行手术，所述第一角和第二角选择成形成所述细长的管状轴在所述近端弯曲部和所述铰链元件之间、大于直径D的最大偏移，以便使所述窗被推靠在所述治疗部位处的血管壁上。
2.根据权利要求1所述的导管，其中，所述近端弯曲部和远端弯曲部构造成位于第一平面内，并且所述铰链元件构造成仅在所述第一平面内允许所述远端部分相对于所述中间部分弯曲。
3.根据权利要求1所述的导管，其中，所述第一角和第二角选择成以在约0.05磅至0.5磅的范围内的力将所述窗推靠在所述血管壁上。
4.根据权利要求1所述的导管，其中，所述第一角处于约90°至150°的范围内，并且所述第二角处于约100°至180°的范围内。
5.根据权利要求1所述的导管，其中，从所述近端弯曲部到所述远端弯曲部的长度大于从所述远端弯曲部到所述铰链元件的长度。
6.根据权利要求1所述的导管，其中，所述远端弯曲部和近端弯曲部之间的长度处于约0.5英寸至2.0英寸的范围内。
7.根据权利要求1所述的导管，其中，所述远端弯曲部和所述铰链元件之间的长度处于约0.375英寸至0.625英寸的范围内。
8.根据权利要求1所述的导管，其中，所述最大偏移处于约3毫米至40毫米的范围内。
9.根据权利要求1所述的导管，还包括轴操纵构件，所述轴操纵构件具有本体，所述本体限定内腔，所述内腔的尺寸设定成接受所述细长的管状轴，所述操纵构件在所述本体内还具有相对的轴接合元件，所述轴接合元件能在锁定位置和解锁位置之间运动，在所述锁定位置中所述轴接合元件接合所述细长的管状轴以将所述本体锁定在所述细长的管状轴上，在所述解锁位置中所述本体自由转动并在所述细长的管状轴上轴向地平移。
10.根据权利要求9所述的导管，其中，在所述解锁位置中所述轴接合元件被偏压。
11.根据权利要求1所述的导管，其中，所述工作元件是粥样斑块切除装置。
12.一种用于在血管的内腔中的治疗部位处执行手术的导管，所述导管包括：
细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有曲线状的远端部分，所述曲线状的远端部分具有连续减小的曲率半径，所述连续减小的曲率半径在第一平面内从所述远端部分的近端到所述细长的管状轴的远端定向，所述远端部分包括铰链元件，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开，所述铰链元件将所述远端部分分成在所述铰链元件和所述细长的管状轴的远端之间的远端分段以及在所述铰链元件和所述远端部分的近端之间的近端分段，所述铰链元件构造成仅在所述第一平面内允许所述远端分段相对于所述近端分段弯曲，所述远端分段包括窗，所述窗在所述铰链元件和所述细长的管状轴的远端之间延伸穿过所述侧壁；和
工作元件，所述工作元件布置在所述细长的管状轴的内腔内，所述工作元件构造成用于穿过所述窗在所述治疗部位处执行手术，所述连续减小的曲率半径选择成在使用期间将所述窗推靠在所述治疗部位处的血管壁上。
13.根据权利要求12所述的导管，其中，所述曲线状的远端部分形成在约90°至720°的范围内的连续的曲线。
14.根据权利要求12所述的导管，其中，所述曲线状的远端部分的最大曲线直径处于约3毫米至50毫米的范围内。
15.根据权利要求12所述的导管，还包括轴操纵构件，所述轴操纵构件具有本体，所述本体限定内腔，所述内腔的尺寸设定成接受所述细长的管状轴，所述轴操纵构件还具有相对的轴接合元件，所述轴接合元件能在锁定位置和解锁位置之间运动，在所述锁定位置中所述轴接合元件接合所述细长的管状轴以将所述本体锁定在所述细长的管状轴上，在所述解锁位置中所述本体自由转动并在所述细长的管状轴上轴向地平移。
16.根据权利要求15所述的导管，其中，在所述解锁位置中所述轴接合元件被偏压。
17.根据权利要求12所述的导管，其中，所述工作元件是粥样斑块切除装置。
18.一种在血管的内腔中的治疗部位处执行手术的方法，所述方法包括：
提供细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，所述细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，所述近端弯曲部限定大于零的第一角，所述远端弯曲部限定大于所述第一角的第二角，所述近端弯曲部和远端弯曲部沿着第一方向定向，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开并且从所述远端弯曲部向远端侧间隔开，所述远端弯曲部定位在所述近端弯曲部和所述铰链元件之间，所述细长的管状轴的远端部分在所述铰链元件和所述细长的管状轴的远端之间延伸，并且所述细长的管状轴的中间部分在所述铰链元件和所述近端弯曲部之间延伸，所述远端部分包括窗，所述窗在所述铰链元件和所述细长的管状轴的远端之间延伸穿过所述侧壁；
将所述细长的管状轴通过所述血管的内腔前进到所述治疗部位；
将所述细长的管状轴定向在这样的位置中，即，在所述位置处所述近端弯曲部和远端弯曲部使所述细长的管状轴的远端部分在所述铰链元件处沿着与所述第一方向相反的第二方向相对于所述细长的管状轴的中间部分弯曲以在所述治疗部位处的期望的位置中将所述窗推靠在血管壁上；以及
在将所述窗推靠在所述血管壁上的同时，借助布置在所述细长的管状轴的内腔内的工作元件在所述治疗部位处穿过所述窗执行手术。
19.根据权利要求18所述的方法，其中，所述铰链元件构造成仅沿着所述第一方向和第二方向允许所述远端部分相对于所述中间部分弯曲。
20.根据权利要求18所述的方法，其中，所述第一角和第二角选择成以在约0.05磅至0.5磅的范围内的力将所述窗推靠在所述血管壁上。
21.根据权利要求18所述的方法，其中，所述第一角处于约90°至150°的范围内，并且所述第二角处于约100°至180°的范围内。
22.根据权利要求18所述的方法，其中，从所述近端弯曲部到所述远端弯曲部的长度大于从所述远端弯曲部到所述铰链元件的长度。
23.根据权利要求18所述的方法，其中，所述远端弯曲部和近端弯曲部之间的长度处于约0.5英寸至2.0英寸的范围内。
24.根据权利要求18所述的方法，其中，所述远端弯曲部和所述铰链元件之间的长度处于约0.375英寸至0.625英寸的范围内。
25.根据权利要求18所述的方法，其中，所述第一角和第二角选择成形成所述细长的管状轴在所述近端弯曲部和铰链元件之间、大于所述治疗部位处的血管直径的最大偏移。
26.根据权利要求18所述的方法，其中，所述工作元件是粥样斑块切除装置，并且所述手术包括从所述血管壁去除材料。
27.一种在血管的内腔中的治疗部位处执行手术的方法，所述方法包括：
提供细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，所述细长的管状轴具有曲线状的远端部分，所述曲线状的远端部分具有连续减小的曲率半径，所述连续减小的曲率半径沿着第一方向从所述远端部分的近端到所述细长的管状轴的远端定向，所述远端部分包括铰链元件，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开，所述铰链元件将所述远端部分分成在所述铰链元件和所述细长的管状轴的远端之间的远端分段以及在所述铰链元件和所述远端部分的近端之间的近端分段，所述铰链元件构造成允许所述远端分段相对于所述近端分段仅沿着所述第一方向和与所述第一方向相反的第二方向弯曲，所述远端分段包括窗，所述窗在所述铰链元件和所述细长的管状轴的远端之间延伸穿过所述侧壁；
将所述细长的管状轴通过所述血管的内腔前进到所述治疗部位；
将所述细长的管状轴定向在这样的位置中，即，在所述位置处所述曲线状的远端部分的连续减小的曲率半径使所述远端分段在所述铰链元件处沿着所述第二方向相对于所述近端分段弯曲以在所述治疗部位处的期望的位置中将所述窗推靠在血管壁上；以及
在将所述窗推靠在所述血管壁上的同时借助布置在所述细长的管状轴的内腔内的工作元件在所述治疗部位处穿过所述窗执行手术。
28.根据权利要求27所述的方法，其中，所述曲线状的远端部分形成在约90°至720°的范围内的连续的曲线。
29.根据权利要求27所述的方法，其中，所述曲线状的远端部分的最大曲线直径处于约3毫米至50毫米的范围内。
30.一种用于操纵导管的轴的装置，所述装置包括：
本体部分，所述本体部分具有内腔，所述内腔的尺寸设定成接收所述导管的轴；和
轴接合构件，所述轴接合构件具有封闭在所述本体部分内的第一轴接合面和第二轴接合面，所述轴接合构件具有锁定位置和解锁位置，在所述锁定位置中所述第一轴接合面和第二轴接合面构造成接合所述轴以将所述本体锁定在所述轴上，在所述解锁位置中所述本体自由转动并在细长的管状轴上轴向地平移。
31.根据权利要求30所述的装置，其中，在所述解锁位置中所述轴接合面被偏压。
32.一种用于接近血管壁上的部位的导管，所述导管包括：
细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，细长的管状轴具有第一弯曲部、第二弯曲部和窗，所述第二弯曲部从所述第一弯曲部向远端侧间隔开预定的距离，所述窗延伸穿过所述侧壁，所述窗定位在所述第二弯曲部的远端侧并且在所述细长的管状构件的远端的近端侧，所述第一弯曲部限定大于零的第一角，所述第二弯曲部限定大于所述第一角的第二角，所述第一角和第二角以及所述预定的距离选择成在使用期间将所述窗推靠在所述血管壁上的所述部位上。
33.根据权利要求32所述的导管，其中，所述细长的管状轴还包括铰链元件，所述铰链元件从所述窗向近端侧间隔开并且从所述第二弯曲部向远端侧间隔开。
34.根据权利要求32所述的导管，还包括工作元件，所述工作元件布置在所述细长的管状轴的内腔内，所述工作元件构造成用于穿过所述窗在所述血管壁上的所述部位处执行手术。
35.根据权利要求33所述的导管，其中，所述细长的管状轴包括在所述铰链元件和所述细长的管状轴的远端之间的远端部分，并且所述铰链元件构造为所述远端部分围绕其弯曲的枢转点。
36.根据权利要求35所述的导管，其中，所述远端部分具有纵向轴线，并且所述铰链元件构造成使得当在使用期间将所述窗推靠在所述血管壁上的所述部位上时，所述远端部分定位成使得所述远端部分的纵向轴线基本上与所述血管的纵向轴线平行。
37.根据权利要求33所述的导管，其中，所述第一弯曲部和第二弯曲部构造成位于第一平面内，并且所述铰链元件构造成仅在所述第一平面内允许所述细长的管状构件向所述铰链元件的远端侧弯曲。
38.根据权利要求32所述的导管，其中，所述第一角和第二角选择成以在约0.05磅至0.5磅的范围内的力将所述窗推靠在所述血管壁上。
39.根据权利要求32所述的导管，其中，所述第一角处于约90°至150°的范围内，并且所述第二角处于约100°至180°的范围内。
40.根据权利要求33所述的导管，其中，从所述第一弯曲部到所述第二弯曲部的长度大于从所述第二弯曲部到所述铰链元件的长度。
41.根据权利要求32所述的导管，其中，所述第一弯曲部和第二弯曲部之间的长度处于约0.5英寸至2.0英寸的范围内。
42.根据权利要求33所述的导管，其中，所述第二弯曲部和所述铰链元件之间的长度处于约0.375英寸至0.625英寸的范围内。
43.根据权利要求34所述的导管，其中，所述工作元件是粥样斑块切除装置。
44.一种用于在血管的内腔中的治疗部位处执行手术的导管，所述导管包括：
细长的管状轴，所述细长的管状轴具有远端和近端以及侧壁，所述侧壁限定内腔，所述细长的管状轴具有近端弯曲部、远端弯曲部和铰链元件，所述近端弯曲部限定大于零的第一角，所述远端弯曲部限定大于所述第一角的第二角，所述铰链元件从所述细长的管状轴的远端向近端侧间隔开并且从所述远端弯曲部向远端侧间隔开，所述远端弯曲部定位在所述近端弯曲部和所述铰链元件之间，所述细长的管状轴的远端部分在所述铰链元件和所述细长的管状轴的远端之间延伸，并且所述细长的管状轴的中间部分在所述铰链元件和所述近端弯曲部之间延伸，所述远端部分包括窗，所述窗在所述铰链元件和所述细长的管状轴的远端之间延伸穿过所述侧壁，所述近端弯曲部、所述远端弯曲部和所述铰链元件构造成在所述治疗部位处将所述窗推靠在血管壁上。
45.根据权利要求44所述的导管，包括工作元件，所述工作元件布置在所述细长的管状轴的内腔内，所述工作元件构造成用于当在使用期间将所述窗推靠在所述血管壁上时穿过所述窗在所述治疗部位处执行手术。
46.根据权利要求44所述的导管，其中，所述近端弯曲部和远端弯曲部构造成位于第一平面内，并且所述铰链元件构造成仅在所述第一平面内允许所述远端部分相对于所述中间部分弯曲。
47.根据权利要求44所述的导管，其中，所述第一角和第二角选择成以在约0.05磅至0.5磅的范围内的力将所述窗推靠在所述血管壁上。
48.根据权利要求44所述的导管，其中，所述第一角处于约90°至150°的范围内，并且所述第二角处于约100°至180°的范围内。
49.根据权利要求44所述的导管，其中，从所述近端弯曲部到所述远端弯曲部的长度大于从所述远端弯曲部到所述铰链元件的长度。
50.根据权利要求44所述的导管，其中，所述远端弯曲部和近端弯曲部之间的长度处于约0.5英寸至2.0英寸的范围内。
51.根据权利要求44所述的导管，其中，所述远端弯曲部和所述铰链元件之间的长度处于约0.375英寸至0.625英寸的范围内。
52.根据权利要求45所述的导管，其中，所述工作元件是粥样斑块切除装置。
CN2009801464405A 2008-10-13 2009-10-13 用于操纵导管轴的装置和方法 Active CN102223847B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10483608P 2008-10-13 2008-10-13
US61/104,836 2008-10-13
US12260108P 2008-12-15 2008-12-15
US61/122,601 2008-12-15
PCT/US2009/060496 WO2010045226A2 (en) 2008-10-13 2009-10-13 Devices and methods for manipulating a catheter shaft

Publications (2)

Publication Number Publication Date
CN102223847A true CN102223847A (zh) 2011-10-19
CN102223847B CN102223847B (zh) 2013-10-30

Family

ID=41664939

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801464405A Active CN102223847B (zh) 2008-10-13 2009-10-13 用于操纵导管轴的装置和方法

Country Status (10)

Country Link
US (3) US8414604B2 (zh)
EP (2) EP2358282B1 (zh)
JP (2) JP5555242B2 (zh)
KR (1) KR101645754B1 (zh)
CN (1) CN102223847B (zh)
AU (1) AU2009303501B2 (zh)
BR (1) BRPI0920206A2 (zh)
CA (1) CA2739665C (zh)
RU (1) RU2503422C2 (zh)
WO (1) WO2010045226A2 (zh)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108368715A (zh) * 2015-10-19 2018-08-03 伊利诺斯工具制品有限公司 包含双铰接声音衰减折片特征的门把手
CN109069180A (zh) * 2016-04-14 2018-12-21 柯惠有限合伙公司 具有调节机构的组织去除导管
CN109069181A (zh) * 2016-04-27 2018-12-21 柯惠有限合伙公司 包括用于旋转和往复运动组织去除元件的驱动组件的导管
CN110944750A (zh) * 2017-05-17 2020-03-31 拜欧迪克斯公司 人体工学流体处理管
CN114470487A (zh) * 2021-12-22 2022-05-13 广东博迈医疗科技股份有限公司 医用导丝及介入医疗设备

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7771444B2 (en) 2000-12-20 2010-08-10 Fox Hollow Technologies, Inc. Methods and devices for removing material from a body lumen
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
US9498600B2 (en) 2009-07-01 2016-11-22 Avinger, Inc. Atherectomy catheter with laterally-displaceable tip
US9125562B2 (en) 2009-07-01 2015-09-08 Avinger, Inc. Catheter-based off-axis optical coherence tomography imaging system
US8696695B2 (en) * 2009-04-28 2014-04-15 Avinger, Inc. Guidewire positioning catheter
US9788790B2 (en) 2009-05-28 2017-10-17 Avinger, Inc. Optical coherence tomography for biological imaging
BRPI0920206A2 (pt) 2008-10-13 2015-12-22 Tyco Healthcare dispositivos e métodos para manipulação de um eixo de cateter
CN102625673B (zh) 2009-04-29 2014-12-24 泰科保健集团有限合伙公司 用于切割和研磨组织的方法及装置
EP2429423B1 (en) 2009-05-14 2015-11-11 Covidien LP Easily cleaned atherectomy catheters
WO2011068932A1 (en) 2009-12-02 2011-06-09 Fox Hollow Technologies, Inc. Methods and devices for cutting tissue
WO2011072068A2 (en) 2009-12-08 2011-06-16 Avinger, Inc. Devices and methods for predicting and preventing restenosis
CA2783301C (en) 2009-12-11 2015-02-24 Tyco Healthcare Group Lp Material removal device having improved material capture efficiency and methods of use
US9119662B2 (en) 2010-06-14 2015-09-01 Covidien Lp Material removal device and method of use
JP2013531542A (ja) 2010-07-01 2013-08-08 アビンガー・インコーポレイテッド 長手方向に移動可能なドライブシャフトを有するアテローム切除カテーテル
US11382653B2 (en) 2010-07-01 2022-07-12 Avinger, Inc. Atherectomy catheter
US10085742B2 (en) * 2010-07-29 2018-10-02 Boston Scientific Scimed, Inc. Adjustable device for delivering implants and methods of delivering implants
BR112013009835A2 (pt) 2010-10-28 2016-07-26 Covidien Lp dispositivo para a remoção de material e método de uso
BR112013011632A2 (pt) 2010-11-11 2016-08-09 Covidien Lp cateteres de citorredução flexíveis com imagiologia e métodos de uso e fabricação
WO2012114629A1 (ja) * 2011-02-25 2012-08-30 テルモ株式会社 固定デバイス及びカテーテルセット
EP3135232B1 (en) 2011-03-28 2018-05-02 Avinger, Inc. Occlusion-crossing devices, imaging, and atherectomy devices
US9949754B2 (en) 2011-03-28 2018-04-24 Avinger, Inc. Occlusion-crossing devices
US8840630B2 (en) * 2011-06-15 2014-09-23 Cook Medical Technologies Llc Button release handle
EP2750862B1 (en) 2011-09-01 2016-07-06 Covidien LP Catheter with helical drive shaft and methods of manufacture
JP6356604B2 (ja) 2011-10-17 2018-07-11 アビンガー・インコーポレイテッドＡｖｉｎｇｅｒ， Ｉｎｃ． アテローム切除カテーテルおよびカテーテル用の非接触型作動機構
US9345406B2 (en) 2011-11-11 2016-05-24 Avinger, Inc. Occlusion-crossing devices, atherectomy devices, and imaging
US9351757B2 (en) 2012-01-17 2016-05-31 Covidien Lp Material removal device and method of use
EP2849661B1 (en) 2012-05-14 2020-12-09 Avinger, Inc. Atherectomy catheters with imaging
EP2849660B1 (en) 2012-05-14 2021-08-25 Avinger, Inc. Atherectomy catheter drive assemblies
EP2849636B1 (en) 2012-05-14 2020-04-22 Avinger, Inc. Optical coherence tomography with graded index fiber for biological imaging
US9498247B2 (en) 2014-02-06 2016-11-22 Avinger, Inc. Atherectomy catheters and occlusion crossing devices
US11284916B2 (en) 2012-09-06 2022-03-29 Avinger, Inc. Atherectomy catheters and occlusion crossing devices
EP2892448B1 (en) 2012-09-06 2020-07-15 Avinger, Inc. Balloon atherectomy catheters with imaging
WO2015120146A1 (en) 2014-02-06 2015-08-13 Avinger, Inc. Atherectomy catheters and occlusion crossing devices
US10335173B2 (en) 2012-09-06 2019-07-02 Avinger, Inc. Re-entry stylet for catheter
US9532844B2 (en) 2012-09-13 2017-01-03 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
JP6110509B2 (ja) * 2012-12-12 2017-04-05 コヴィディエン リミテッド パートナーシップ 押し付け機構を含む組織除去カテーテル
WO2014143064A1 (en) 2013-03-15 2014-09-18 Avinger, Inc. Chronic total occlusion crossing devices with imaging
WO2014142958A1 (en) 2013-03-15 2014-09-18 Avinger, Inc. Optical pressure sensor assembly
WO2014142954A1 (en) 2013-03-15 2014-09-18 Avinger, Inc. Tissue collection device for catheter
EP3019096B1 (en) 2013-07-08 2023-07-05 Avinger, Inc. System for identification of elastic lamina to guide interventional therapy
US9526519B2 (en) * 2014-02-03 2016-12-27 Covidien Lp Tissue-removing catheter with improved angular tissue-removing positioning within body lumen
US9456843B2 (en) * 2014-02-03 2016-10-04 Covidien Lp Tissue-removing catheter including angular displacement sensor
JP5954747B2 (ja) * 2014-03-20 2016-07-20 朝日インテック株式会社 カテーテル
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
EP3166512B1 (en) 2014-07-08 2020-08-19 Avinger, Inc. High speed chronic total occlusion crossing devices
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10568520B2 (en) 2015-07-13 2020-02-25 Avinger, Inc. Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10179046B2 (en) * 2015-08-14 2019-01-15 Edwards Lifesciences Corporation Gripping and pushing device for medical instrument
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
US11278248B2 (en) 2016-01-25 2022-03-22 Avinger, Inc. OCT imaging catheter with lag correction
JP6959255B2 (ja) 2016-04-01 2021-11-02 アビンガー・インコーポレイテッドＡｖｉｎｇｅｒ， Ｉｎｃ． 粥腫切除用カテーテルデバイス
US11344327B2 (en) 2016-06-03 2022-05-31 Avinger, Inc. Catheter device with detachable distal end
CN109414273B (zh) * 2016-06-30 2023-02-17 阿维格公司 具有可塑形的远侧头端的斑块切除导管
EP3515321A2 (en) * 2016-09-21 2019-07-31 3NT Medical Ltd. Seeker with dilator
US20180311468A1 (en) * 2017-04-27 2018-11-01 The Regents Of The University Of California Force sensor and monitoring device
US10874839B2 (en) * 2017-07-13 2020-12-29 Acclarent, Inc. Adjustable instrument for dilation of anatomical passageway
WO2021076356A1 (en) 2019-10-18 2021-04-22 Avinger, Inc. Occlusion-crossing devices
WO2023107922A1 (en) * 2021-12-06 2023-06-15 Avinger, Inc. Atherectomy catheter with shapeable distal tip

Family Cites Families (609)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1481078A (en) 1922-11-24 1924-01-15 Albertson & Company Flexible shafting
US2178790A (en) 1938-05-07 1939-11-07 Abner E Henry Cutting implement
US2234686A (en) * 1940-01-02 1941-03-11 Ind Patents Corp Needle and clamp therefor
US2701559A (en) 1951-08-02 1955-02-08 William A Cooper Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera
US2850007A (en) 1956-05-31 1958-09-02 American Cyanamid Co Biopsy device
US3064651A (en) 1959-05-26 1962-11-20 Henderson Edward Hypodermic needle
US3082805A (en) 1960-12-21 1963-03-26 John H Royce Tissue macerator
US3320957A (en) 1964-05-21 1967-05-23 Sokolik Edward Surgical instrument
GB1235321A (en) 1968-01-30 1971-06-09 Nat Res Dev Improvements in or relating to drills for clearing obstructions
US3732858A (en) 1968-09-16 1973-05-15 Surgical Design Corp Apparatus for removing blood clots, cataracts and other objects from the eye
ES152231Y (es) 1969-10-02 1970-07-01 Ballestero Sierra Un trocar perfeccionado.
US3749085A (en) 1970-06-26 1973-07-31 J Willson Vascular tissue removing device
US3683891A (en) 1970-06-26 1972-08-15 Marshall Eskridge Tissue auger
US3945375A (en) 1972-04-04 1976-03-23 Surgical Design Corporation Rotatable surgical instrument
SU442795A1 (ru) 1972-04-27 1974-09-15 Л.С. Юхин Устройство дл внутрисосудистых операций
US3815604A (en) 1972-06-19 1974-06-11 Malley C O Apparatus for intraocular surgery
US3800783A (en) 1972-06-22 1974-04-02 K Jamshidi Muscle biopsy device
US3831585A (en) 1972-07-19 1974-08-27 T Brondy Retrograde renal biopsy device
JPS5042162A (zh) 1973-08-21 1975-04-17
US3837345A (en) 1973-08-31 1974-09-24 A Matar Venous valve snipper
JPS5529376B2 (zh) 1973-09-17 1980-08-02
US3937222A (en) 1973-11-09 1976-02-10 Surgical Design Corporation Surgical instrument employing cutter means
US3845375A (en) 1973-11-09 1974-10-29 Mclaughlin Ward & Co Electronic rotational sensor
JPS5184679A (ja) 1975-01-24 1976-07-24 Niino Giken Kk Biatsukanchowakutaitsukidaiyafuramuno seizohoho
US3976077A (en) 1975-02-03 1976-08-24 Kerfoot Jr Franklin W Eye surgery device
US4007732A (en) 1975-09-02 1977-02-15 Robert Carl Kvavle Method for location and removal of soft tissue in human biopsy operations
US4038985A (en) 1975-10-07 1977-08-02 Medico Developments, Inc. Device for repairing arteries
US3995619A (en) 1975-10-14 1976-12-07 Glatzer Stephen G Combination subcutaneous suture remover, biopsy sampler and syringe
US4030503A (en) 1975-11-05 1977-06-21 Clark Iii William T Embolectomy catheter
US4020847A (en) 1975-11-05 1977-05-03 Clark Iii William T Rotating cutter catheter
US4034744A (en) 1975-11-13 1977-07-12 Smith Kline Instruments, Inc. Ultrasonic scanning system with video recorder
US4177797A (en) 1977-03-04 1979-12-11 Shelby M. Baylis Rotary biopsy device and method of using same
US4112708A (en) 1976-06-21 1978-09-12 Nippon Cable Systems Inc. Flexible drive cable
SU665908A1 (ru) 1977-11-09 1979-06-05 Silin Semen A Устройство дл внутрисосудистых операций
US4210146A (en) 1978-06-01 1980-07-01 Anton Banko Surgical instrument with flexible blade
US4306562A (en) 1978-12-01 1981-12-22 Cook, Inc. Tear apart cannula
JPS5581633A (en) 1978-12-15 1980-06-19 Olympus Optical Co Endoscope
US4362156A (en) * 1979-04-18 1982-12-07 Riverain Corporation Intravenous infusion assembly
DE2949865C2 (de) * 1979-12-12 1985-04-18 B. Braun Melsungen Ag, 3508 Melsungen Schlauchverbindung für medizinische Geräte
US4273128A (en) 1980-01-14 1981-06-16 Lary Banning G Coronary cutting and dilating instrument
US4306570A (en) 1980-08-20 1981-12-22 Matthews Larry S Counter rotating biopsy needle
US4368730A (en) 1981-02-12 1983-01-18 Nigel Sharrock Intravenous catheter
GB2093353B (en) 1981-02-25 1984-09-19 Dyonics Inc A surgical instrument for arthroscopic arthroplasty
US4436091A (en) 1981-03-20 1984-03-13 Surgical Design Corporation Surgical cutting instrument with release mechanism
JPS5887494U (ja) 1981-12-05 1983-06-14 株式会社モリタ製作所 医療用小型モ−タの速度制御装置
CH660015A5 (de) 1982-02-01 1987-03-13 Sandoz Ag Polymerisat- und tensidhaltige praeparate, deren herstellung und verwendung.
US4445509A (en) 1982-02-04 1984-05-01 Auth David C Method and apparatus for removal of enclosed abnormal deposits
US4692141A (en) 1982-03-08 1987-09-08 Mahurkar Sakharam D Double lumen catheter
US4512344A (en) 1982-05-12 1985-04-23 Barber Forest C Arthroscopic surgery dissecting apparatus
US4424045A (en) 1982-05-24 1984-01-03 Pennwalt Corporation Rigid high speed flexible shaft casing assembly for tight radii installations
DE3235612A1 (de) 1982-09-25 1984-03-29 Bayer Ag, 5090 Leverkusen Mikroemulsionen
US4490139A (en) 1983-01-28 1984-12-25 Eli Lilly And Company Implant needle and method
US4936987A (en) 1983-03-07 1990-06-26 Calgon Corporation Synergistic scale and corrosion inhibiting admixtures containing carboxylic acid/sulfonic acid polymers
US4603694A (en) 1983-03-08 1986-08-05 Richards Medical Company Arthroscopic shaver
US4730616A (en) 1983-08-12 1988-03-15 Advanced Cardiovascular Systems, Inc. Multiple probe angioplasty apparatus and method
US5669936A (en) 1983-12-09 1997-09-23 Endovascular Technologies, Inc. Endovascular grafting system and method for use therewith
US5104399A (en) 1986-12-10 1992-04-14 Endovascular Technologies, Inc. Artificial graft and implantation method
DE3347671A1 (de) 1983-12-31 1985-07-11 Richard Wolf Gmbh, 7134 Knittlingen Instrument zur entnahme von gewebeproben
US4631052A (en) 1984-01-03 1986-12-23 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
US4589412A (en) 1984-01-03 1986-05-20 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
US5024651A (en) 1984-05-14 1991-06-18 Surgical Systems & Instruments, Inc. Atherectomy system with a sleeve
US4894051A (en) 1984-05-14 1990-01-16 Surgical Systems & Instruments, Inc. Atherectomy system with a biasing sleeve and method of using the same
US4886490A (en) 1984-05-14 1989-12-12 Surgical Systems & Instruments, Inc. Atherectomy catheter system and method of using the same
US4883458A (en) 1987-02-24 1989-11-28 Surgical Systems & Instruments, Inc. Atherectomy system and method of using the same
US5007896A (en) 1988-12-19 1991-04-16 Surgical Systems & Instruments, Inc. Rotary-catheter for atherectomy
US4842579B1 (en) 1984-05-14 1995-10-31 Surgical Systems & Instr Inc Atherectomy device
US5135531A (en) 1984-05-14 1992-08-04 Surgical Systems & Instruments, Inc. Guided atherectomy system
US4979939A (en) 1984-05-14 1990-12-25 Surgical Systems & Instruments, Inc. Atherectomy system with a guide wire
US5002553A (en) 1984-05-14 1991-03-26 Surgical Systems & Instruments, Inc. Atherectomy system with a clutch
US4754755A (en) 1984-05-14 1988-07-05 Husted Royce Hill Catheter with a rotary blade
US4732154A (en) 1984-05-14 1988-03-22 Surgical Systems & Instruments, Inc. Rotary catheter system
US4819634A (en) 1984-05-14 1989-04-11 Surgical Systems & Instruments Rotary-catheter for atherectomy system
US4957482A (en) 1988-12-19 1990-09-18 Surgical Systems & Instruments, Inc. Atherectomy device with a positive pump means
US4979951A (en) 1984-05-30 1990-12-25 Simpson John B Atherectomy device and method
US4926858A (en) 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
US4781186A (en) 1984-05-30 1988-11-01 Devices For Vascular Intervention, Inc. Atherectomy device having a flexible housing
US4646719A (en) 1984-06-11 1987-03-03 Aries Medical Incorporated Intra-aortic balloon catheter having flexible torque transmitting tube
USRE33258E (en) 1984-07-23 1990-07-10 Surgical Dynamics Inc. Irrigating, cutting and aspirating system for percutaneous surgery
US4646736A (en) 1984-09-10 1987-03-03 E. R. Squibb & Sons, Inc. Transluminal thrombectomy apparatus
US4649919A (en) 1985-01-23 1987-03-17 Precision Surgical Instruments, Inc. Surgical instrument
US4705038A (en) 1985-01-23 1987-11-10 Dyonics, Inc. Surgical system for powered instruments
US4653496A (en) 1985-02-01 1987-03-31 Bundy Mark A Transluminal lysing system
US4745919A (en) 1985-02-01 1988-05-24 Bundy Mark A Transluminal lysing system
US4686982A (en) 1985-06-19 1987-08-18 John Nash Spiral wire bearing for rotating wire drive catheter
US4747406A (en) 1985-02-13 1988-05-31 Intravascular Surgical Instruments, Inc. Shaft driven, flexible intravascular recanalization catheter
US4706671A (en) 1985-05-02 1987-11-17 Weinrib Harry P Catheter with coiled tip
US4679558A (en) 1985-08-12 1987-07-14 Intravascular Surgical Instruments, Inc. Catheter based surgical methods and apparatus therefor
US4664112A (en) 1985-08-12 1987-05-12 Intravascular Surgical Instruments, Inc. Catheter based surgical methods and apparatus therefor
EP0216004A3 (en) 1985-09-20 1987-06-16 Union Carbide Corporation A galvanic cell having an improved safety vent construction
US4790812A (en) 1985-11-15 1988-12-13 Hawkins Jr Irvin F Apparatus and method for removing a target object from a body passsageway
US4696298A (en) 1985-11-19 1987-09-29 Storz Instrument Company Vitrectomy cutting mechanism
US4646738A (en) 1985-12-05 1987-03-03 Concept, Inc. Rotary surgical tool
CA1293663C (en) 1986-01-06 1991-12-31 David Christopher Auth Transluminal microdissection device
AU607692B2 (en) 1986-01-06 1991-03-14 Boston Scientific Corporation Northwest Technology Center, Inc. Transluminal microdissection device
US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
US4771774A (en) 1986-02-28 1988-09-20 Devices For Vascular Intervention, Inc. Motor drive unit
US4794931A (en) 1986-02-28 1989-01-03 Cardiovascular Imaging Systems, Inc. Catheter apparatus, system and method for intravascular two-dimensional ultrasonography
US4669469A (en) 1986-02-28 1987-06-02 Devices For Vascular Intervention Single lumen atherectomy catheter device
US4696667A (en) 1986-03-20 1987-09-29 Helmut Masch Intravascular catheter and method
US4728319A (en) 1986-03-20 1988-03-01 Helmut Masch Intravascular catheter
US5350395A (en) 1986-04-15 1994-09-27 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US4757819A (en) 1986-05-21 1988-07-19 Olympus Optical Co., Ltd. Ultrasonic endoscope
US4729763A (en) 1986-06-06 1988-03-08 Henrie Rodney A Catheter for removing occlusive material
US4765332A (en) 1986-07-14 1988-08-23 Medinnovations, Inc. Pullback atherectomy catheter system
US4747821A (en) 1986-10-22 1988-05-31 Intravascular Surgical Instruments, Inc. Catheter with high speed moving working head
US4749376A (en) 1986-10-24 1988-06-07 Intravascular Surgical Instruments, Inc. Reciprocating working head catheter
SE455834B (sv) 1986-10-31 1988-08-15 Medinvent Sa Anordning for transluminal implantation av en i huvudsak rorformig, radiellt expanderbar protes
US4733662A (en) 1987-01-20 1988-03-29 Minnesota Mining And Manufacturing Company Tissue gripping and cutting assembly for surgical instrument
US4733622A (en) * 1987-02-24 1988-03-29 Ssmc Inc. Thread end holder for sewing machine with thread winding bobbin
US4923462A (en) 1987-03-17 1990-05-08 Cordis Corporation Catheter system having a small diameter rotatable drive member
US4846192A (en) 1987-04-17 1989-07-11 Eastman Kodak Company Rearwardly acting surgical catheter
US4784636A (en) 1987-04-30 1988-11-15 Schneider-Shiley (U.S.A.) Inc. Balloon atheroectomy catheter
US4817613A (en) 1987-07-13 1989-04-04 Devices For Vascular Intervention, Inc. Guiding catheter
US4954338A (en) 1987-08-05 1990-09-04 Rohm And Haas Company Microbicidal microemulsion
US4867157A (en) 1987-08-13 1989-09-19 Baxter Travenol Laboratories, Inc. Surgical cutting instrument
US4819635A (en) 1987-09-18 1989-04-11 Henry Shapiro Tubular microsurgery cutting apparatus
DE3732236C1 (de) 1987-09-24 1988-12-15 Rainer Dr Baumgart Rekanalisationskatheter
US4844064A (en) 1987-09-30 1989-07-04 Baxter Travenol Laboratories, Inc. Surgical cutting instrument with end and side openings
US5154705A (en) 1987-09-30 1992-10-13 Lake Region Manufacturing Co., Inc. Hollow lumen cable apparatus
US5165421A (en) 1987-09-30 1992-11-24 Lake Region Manufacturing Co., Inc. Hollow lumen cable apparatus
US4857046A (en) 1987-10-21 1989-08-15 Cordis Corporation Drive catheter having helical pump drive shaft
US5047040A (en) 1987-11-05 1991-09-10 Devices For Vascular Intervention, Inc. Atherectomy device and method
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US4887613A (en) 1987-11-23 1989-12-19 Interventional Technologies Inc. Cutter for atherectomy device
NZ222930A (en) 1987-12-15 1990-08-28 Moffat Appliances Ltd Gas infra-red burner in heat exchanger
US4850957A (en) 1988-01-11 1989-07-25 American Biomed, Inc. Atherectomy catheter
US5053044A (en) 1988-01-11 1991-10-01 Devices For Vascular Intervention, Inc. Catheter and method for making intravascular incisions
DE3801318A1 (de) 1988-01-19 1989-07-27 Stocksmeier Uwe Medizinischer katheter mit schneidvorrichtung
US4886061A (en) 1988-02-09 1989-12-12 Medinnovations, Inc. Expandable pullback atherectomy catheter system
US4899757A (en) 1988-02-22 1990-02-13 Intertherapy, Inc. Ultrasound imaging probe with zero dead space
EP0330843B1 (de) 1988-03-04 1993-12-22 ANGIOMED Aktiengesellschaft Verfahren und Vorrichtung zum Entfernen von Ablagerungen in Gefässen und Organen von Lebewesen
US4838268A (en) 1988-03-07 1989-06-13 Scimed Life Systems, Inc. Non-over-the wire balloon catheter
US5183432A (en) 1988-03-19 1993-02-02 Nihonmatai Co., Ltd. Floating body of sophisticated shape produced from a single sheet of film with a single sealing
US5372138A (en) 1988-03-21 1994-12-13 Boston Scientific Corporation Acousting imaging catheters and the like
US5368035A (en) 1988-03-21 1994-11-29 Boston Scientific Corporation Ultrasound imaging guidewire
US4935017A (en) 1988-04-29 1990-06-19 C. R. Bard, Inc. Variable shaped catheter system and method for catheterization
US4950238A (en) 1988-07-07 1990-08-21 Clarence E. Sikes Hydro-rotary vascular catheter
US4919133A (en) 1988-08-18 1990-04-24 Chiang Tien Hon Catheter apparatus employing shape memory alloy structures
US5071425A (en) 1988-09-12 1991-12-10 Devices For Vascular Intervention, Inc. Atherectomy catheter and method of forming the same
GB8822149D0 (en) 1988-09-21 1988-10-26 Ciba Geigy Ag Treatment of aqueous systems
DE8813144U1 (de) 1988-10-19 1988-12-15 Günther, Rolf W., Prof. Dr., 5100 Aachen Vorrichtung zur perkutanen Entfernung von Thromben und Emboli
GB8829182D0 (en) 1988-12-14 1989-01-25 Univ Birmingham Surgical instrument
DE8900059U1 (de) 1989-01-04 1989-05-24 Schneider (Europe) AG, Zürich Katheter zur Behandlung arterieller Thrombosen
WO1990007303A1 (en) 1989-01-06 1990-07-12 Angioplasty Systems, Inc. Electrosurgical catheter for resolving atherosclerotic plaque
US4986807A (en) 1989-01-23 1991-01-22 Interventional Technologies, Inc. Atherectomy cutter with radially projecting blade
US4966604A (en) 1989-01-23 1990-10-30 Interventional Technologies Inc. Expandable atherectomy cutter with flexibly bowed blades
US5077506A (en) 1989-02-03 1991-12-31 Dyonics, Inc. Microprocessor controlled arthroscopic surgical system
US5431673A (en) 1989-02-17 1995-07-11 American Biomed, Inc. Distal atherectomy catheter
US4994067A (en) 1989-02-17 1991-02-19 American Biomed, Inc. Distal atherectomy catheter
US5087265A (en) 1989-02-17 1992-02-11 American Biomed, Inc. Distal atherectomy catheter
US4928693A (en) 1989-03-13 1990-05-29 Schneider (Usa), Inc. Pressure monitor catheter
US5078723A (en) 1989-05-08 1992-01-07 Medtronic, Inc. Atherectomy device
EP0401158B1 (de) 1989-06-01 1996-02-28 Schneider (Europe) Ag Katheteranordnung mit einem Führungsdraht sowie Verfahren zur Herstellung eines solchen Führungsdrahtes
US5029588A (en) 1989-06-15 1991-07-09 Cardiovascular Imaging Systems, Inc. Laser catheter with imaging capability
US5226910A (en) 1989-07-05 1993-07-13 Kabushiki Kaisha Topcon Surgical cutter
US5269793A (en) 1989-07-20 1993-12-14 Devices For Vascular Intervention, Inc. Guide wire systems for intravascular catheters
US5100426A (en) 1989-07-26 1992-03-31 Fts Engineering, Inc. Catheter for performing an atherectomy procedure
US5282484A (en) 1989-08-18 1994-02-01 Endovascular Instruments, Inc. Method for performing a partial atherectomy
US5115814A (en) 1989-08-18 1992-05-26 Intertherapy, Inc. Intravascular ultrasonic imaging probe and methods of using same
US5211651A (en) 1989-08-18 1993-05-18 Evi Corporation Catheter atherotome
US5226909A (en) 1989-09-12 1993-07-13 Devices For Vascular Intervention, Inc. Atherectomy device having helical blade and blade guide
US4997435A (en) 1989-09-25 1991-03-05 Methodist Hospital Of Indiana Inc. Percutaneous catheter with encapsulating receptacle
US5092839A (en) 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
US5116352A (en) 1989-10-06 1992-05-26 Angiomed Ag Apparatus for removing deposits from vessels
US5049124A (en) 1989-10-14 1991-09-17 Dow Corning Wright Corporation Catheter drive apparatus having fluid delivery bearing
US5024234A (en) 1989-10-17 1991-06-18 Cardiovascular Imaging Systems, Inc. Ultrasonic imaging catheter with guidewire channel
US5009659A (en) 1989-10-30 1991-04-23 Schneider (Usa) Inc. Fiber tip atherectomy catheter
US5127626A (en) * 1989-10-31 1992-07-07 Applied Vascular Devices, Inc. Apparatus for sealing around members extending therethrough
ZA908425B (en) 1989-11-03 1991-07-31 Rohm & Haas Synergistic microbicidal combinations
US5505210A (en) 1989-11-06 1996-04-09 Mectra Labs, Inc. Lavage with tissue cutting cannula
US5019088A (en) 1989-11-07 1991-05-28 Interventional Technologies Inc. Ovoid atherectomy cutter
US5026384A (en) 1989-11-07 1991-06-25 Interventional Technologies, Inc. Atherectomy systems and methods
US5085662A (en) 1989-11-13 1992-02-04 Scimed Life Systems, Inc. Atherectomy catheter and related components
US5030201A (en) 1989-11-24 1991-07-09 Aubrey Palestrant Expandable atherectomy catheter device
US5178625A (en) 1989-12-07 1993-01-12 Evi Corporation Catheter atherotome
US5011490A (en) 1989-12-07 1991-04-30 Medical Innovative Technologies R&D Limited Partnership Endoluminal tissue excision catheter system and method
US5003918A (en) 1989-12-28 1991-04-02 Interventional Technologies, Inc. Apparatus for manufacturing atherectomy torque tubes
US5120323A (en) 1990-01-12 1992-06-09 Schneider (Usa) Inc. Telescoping guide catheter system
JP2506213B2 (ja) 1990-01-12 1996-06-12 宇部興産株式会社 カテ―テル
US5916210A (en) 1990-01-26 1999-06-29 Intraluminal Therapeutics, Inc. Catheter for laser treatment of atherosclerotic plaque and other tissue abnormalities
US5074841A (en) 1990-01-30 1991-12-24 Microcision, Inc. Atherectomy device with helical cutter
US5152744A (en) 1990-02-07 1992-10-06 Smith & Nephew Dyonics Surgical instrument
US5084010A (en) 1990-02-20 1992-01-28 Devices For Vascular Intervention, Inc. System and method for catheter construction
US5222966A (en) 1990-02-28 1993-06-29 Devices For Vascular Intervention, Inc. Balloon connection and inflation lumen for atherectomy catheter
US5092873A (en) 1990-02-28 1992-03-03 Devices For Vascular Intervention, Inc. Balloon configuration for atherectomy catheter
US5366463A (en) 1990-05-02 1994-11-22 Ryan William J Atherectomy catheter for the removal of atherosclerosis from within blood vessels
US5267955A (en) 1990-05-10 1993-12-07 Lake Region Manufacturing Company, Inc. Atherectomy device
US5395311A (en) 1990-05-14 1995-03-07 Andrews; Winston A. Atherectomy catheter
US5154724A (en) 1990-05-14 1992-10-13 Andrews Winston A Atherectomy catheter
US5095911A (en) 1990-05-18 1992-03-17 Cardiovascular Imaging Systems, Inc. Guidewire with imaging capability
US5558093A (en) 1990-05-18 1996-09-24 Cardiovascular Imaging Systems, Inc. Guidewire with imaging capability
US5100424A (en) 1990-05-21 1992-03-31 Cardiovascular Imaging Systems, Inc. Intravascular catheter having combined imaging abrasion head
US5674232A (en) 1990-06-05 1997-10-07 Halliburton; Alexander George Catheter and method of use thereof
US5181920A (en) 1990-06-08 1993-01-26 Devices For Vascular Intervention, Inc. Atherectomy device with angioplasty balloon and method
US5360443A (en) 1990-06-11 1994-11-01 Barone Hector D Aortic graft for repairing an abdominal aortic aneurysm
US5527298A (en) 1990-06-11 1996-06-18 Schneider (Usa) Inc. Tracking guidewire
JPH06114070A (ja) 1990-06-22 1994-04-26 Vance Prod Inc 外科用組織切除装置
US5064435A (en) 1990-06-28 1991-11-12 Schneider (Usa) Inc. Self-expanding prosthesis having stable axial length
US5520189A (en) 1990-07-13 1996-05-28 Coraje, Inc. Intravascular ultrasound imaging guidewire
CA2048120A1 (en) 1990-08-06 1992-02-07 William J. Drasler Thrombectomy method and device
US5078722A (en) 1990-08-14 1992-01-07 Cordis Corporation Method and apparatus for removing deposits from a vessel
US5100423A (en) 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5127902A (en) 1990-09-05 1992-07-07 Medical Innovative Technologies R&D Limited Partnership Apparatus and method for precisely controlling the excision of obstructive tissue in a human blood vessel
US5250065A (en) 1990-09-11 1993-10-05 Mectra Labs, Inc. Disposable lavage tip assembly
US5114399A (en) 1990-10-01 1992-05-19 Intramed Laboratories Surgical device
US5190528A (en) 1990-10-19 1993-03-02 Boston University Percutaneous transseptal left atrial cannulation system
US5242460A (en) 1990-10-25 1993-09-07 Devices For Vascular Intervention, Inc. Atherectomy catheter having axially-disposed cutting edge
US5527292A (en) 1990-10-29 1996-06-18 Scimed Life Systems, Inc. Intravascular device for coronary heart treatment
US5496267A (en) 1990-11-08 1996-03-05 Possis Medical, Inc. Asymmetric water jet atherectomy
DE4036570A1 (de) 1990-11-16 1992-05-21 Osypka Peter Katheter zur verminderung oder beseitigung von verengungen in gefaessen
JP2550778B2 (ja) 1990-11-30 1996-11-06 富士写真光機株式会社 超音波検査装置
US5108500A (en) 1990-12-10 1992-04-28 Rohm And Haas Company Stabilization of water insoluble 3-isothiazolones
US5112345A (en) 1990-12-17 1992-05-12 Interventional Technologies Atherectomy cutter with arcuate blades
US5054492A (en) 1990-12-17 1991-10-08 Cardiovascular Imaging Systems, Inc. Ultrasonic imaging catheter having rotational image correlation
US5110822A (en) 1991-01-03 1992-05-05 Rohm And Haas Company Synergistic combinations of 4,5-dichloro-2-n-octyl-3-isothiazolone or 2-methyl-3-isothiazolone with ferric dimethyl dithiocarbamate fungicide
CA2075973A1 (en) 1991-02-19 1992-08-20 Robert E. Fischell Apparatus and method for atherectomy
US5445155A (en) 1991-03-13 1995-08-29 Scimed Life Systems Incorporated Intravascular imaging apparatus and methods for use and manufacture
US5295958A (en) 1991-04-04 1994-03-22 Shturman Cardiology Systems, Inc. Method and apparatus for in vivo heart valve decalcification
CA2065634C (en) 1991-04-11 1997-06-03 Alec A. Piplani Endovascular graft having bifurcation and apparatus and method for deploying the same
US6134003A (en) 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
WO1992019930A1 (en) 1991-04-29 1992-11-12 Massachusetts Institute Of Technology Method and apparatus for optical imaging and measurement
US6501551B1 (en) 1991-04-29 2002-12-31 Massachusetts Institute Of Technology Fiber optic imaging endoscope interferometer with at least one faraday rotator
IT1249059B (it) 1991-05-22 1995-02-11 Rosa Antonio Dissettore-scollatore ad ultrasuoni di placche aterosclerotiche
US5395335A (en) 1991-05-24 1995-03-07 Jang; G. David Universal mode vascular catheter system
US5569275A (en) 1991-06-11 1996-10-29 Microvena Corporation Mechanical thrombus maceration device
US5284486A (en) 1991-06-11 1994-02-08 Microvena Corporation Self-centering mechanical medical device
US5263928A (en) 1991-06-14 1993-11-23 Baxter International Inc. Catheter and endoscope assembly and method of use
US5273526A (en) 1991-06-21 1993-12-28 Lake Region Manufacturing Company, Inc. Vascular occulusion removal devices and method
US5217474A (en) 1991-07-15 1993-06-08 Zacca Nadim M Expandable tip atherectomy method and apparatus
US5242461A (en) 1991-07-22 1993-09-07 Dow Corning Wright Variable diameter rotating recanalization catheter and surgical method
US5261877A (en) 1991-07-22 1993-11-16 Dow Corning Wright Method of performing a thrombectomy procedure
US5336167A (en) 1991-07-22 1994-08-09 Theratek International, Inc. Controller for intravascular catheter system
JPH0542162A (ja) 1991-08-15 1993-02-23 Nissho Corp 塞栓切除カテ−テル
JP3084830B2 (ja) 1991-08-29 2000-09-04 株式会社ニッショー 塞栓切除カテ−テル
US5377682A (en) 1991-09-05 1995-01-03 Matsushita Electric Industrial Co., Ltd. Ultrasonic probe for transmission and reception of ultrasonic wave and ultrasonic diagnostic apparatus including ultrasonic probe
US5285795A (en) 1991-09-12 1994-02-15 Surgical Dynamics, Inc. Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula
US5423846A (en) 1991-10-21 1995-06-13 Cathco, Inc. Dottering auger catheter system
US5263959A (en) 1991-10-21 1993-11-23 Cathco, Inc. Dottering auger catheter system and method
CA2081424C (en) 1991-10-25 2008-12-30 Timothy A. Chuter Expandable transluminal graft prosthesis for repair of aneurysm
US5316023A (en) 1992-01-08 1994-05-31 Expandable Grafts Partnership Method for bilateral intra-aortic bypass
US5224949A (en) 1992-01-13 1993-07-06 Interventional Technologies, Inc. Camming device
ATE166780T1 (de) 1992-01-13 1998-06-15 Schneider Usa Inc Schneideinrichtung für atherektomie-katheter
US5224945A (en) 1992-01-13 1993-07-06 Interventional Technologies, Inc. Compressible/expandable atherectomy cutter
US5192291A (en) 1992-01-13 1993-03-09 Interventional Technologies, Inc. Rotationally expandable atherectomy cutter assembly
DE69218794T2 (de) 1992-01-13 1997-07-10 Schneider Usa Inc Chirurgisches schneidinstrument
US5250059A (en) 1992-01-22 1993-10-05 Devices For Vascular Intervention, Inc. Atherectomy catheter having flexible nose cone
US5318032A (en) 1992-02-05 1994-06-07 Devices For Vascular Intervention Guiding catheter having soft tip
EP0626823B1 (en) 1992-02-21 2000-04-19 Boston Scientific Limited Ultrasound imaging guidewire
US5295493A (en) 1992-03-19 1994-03-22 Interventional Technologies, Inc. Anatomical guide wire
US5350390A (en) 1992-03-25 1994-09-27 Arieh Sher Device for removal of intraluminal occlusions
US5176693A (en) 1992-05-11 1993-01-05 Interventional Technologies, Inc. Balloon expandable atherectomy cutter
US5269759A (en) 1992-07-28 1993-12-14 Cordis Corporation Magnetic guidewire coupling for vascular dilatation apparatus
US5306294A (en) 1992-08-05 1994-04-26 Ultrasonic Sensing And Monitoring Systems, Inc. Stent construction of rolled configuration
US5707376A (en) 1992-08-06 1998-01-13 William Cook Europe A/S Stent introducer and method of use
US5224488A (en) 1992-08-31 1993-07-06 Neuffer Francis H Biopsy needle with extendable cutting means
US5397311A (en) * 1992-09-09 1995-03-14 Menlo Care, Inc. Bloodless splittable introducer
US5383460A (en) 1992-10-05 1995-01-24 Cardiovascular Imaging Systems, Inc. Method and apparatus for ultrasound imaging and atherectomy
US5356418A (en) 1992-10-28 1994-10-18 Shturman Cardiology Systems, Inc. Apparatus and method for rotational atherectomy
US5312427A (en) 1992-10-16 1994-05-17 Shturman Cardiology Systems, Inc. Device and method for directional rotational atherectomy
US5360432A (en) 1992-10-16 1994-11-01 Shturman Cardiology Systems, Inc. Abrasive drive shaft device for directional rotational atherectomy
JP3186256B2 (ja) 1992-10-21 2001-07-11 セイコーエプソン株式会社 Ｔａｂ用フレキシブル回路基板の製造方法
US5531690A (en) 1992-10-30 1996-07-02 Cordis Corporation Rapid exchange catheter
US5336178A (en) 1992-11-02 1994-08-09 Localmed, Inc. Intravascular catheter with infusion array
US5643297A (en) 1992-11-09 1997-07-01 Endovascular Instruments, Inc. Intra-artery obstruction clearing apparatus and methods
US5571122A (en) 1992-11-09 1996-11-05 Endovascular Instruments, Inc. Unitary removal of plaque
US5540707A (en) 1992-11-13 1996-07-30 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5792157A (en) 1992-11-13 1998-08-11 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5501694A (en) 1992-11-13 1996-03-26 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5372602A (en) 1992-11-30 1994-12-13 Device For Vascular Intervention, Inc. Method of removing plaque using catheter cutter with torque control
WO1994012234A1 (en) 1992-12-01 1994-06-09 Intelliwire, Inc. Vibratory element for crossing stenoses
US5584842A (en) 1992-12-02 1996-12-17 Intramed Laboratories, Inc. Valvulotome and method of using
US5318576A (en) 1992-12-16 1994-06-07 Plassche Jr Walter M Endovascular surgery systems
US5373849A (en) 1993-01-19 1994-12-20 Cardiovascular Imaging Systems, Inc. Forward viewing imaging catheter
US5620447A (en) 1993-01-29 1997-04-15 Smith & Nephew Dyonics Inc. Surgical instrument
CA2114330A1 (en) 1993-01-29 1994-07-30 Smith & Nephew Endoscopy, Inc. Rotatable curved instrument
DE9303531U1 (de) 1993-03-11 1994-07-14 Redha, Falah, Dr., Kloten Medizinisches Instrument
US5378234A (en) 1993-03-15 1995-01-03 Pilot Cardiovascular Systems, Inc. Coil polymer composite
CH685738A5 (fr) 1993-03-25 1995-09-29 Ferromec Sa Instrument médical pour l'élimination de dépôts formés sur les parois intérieures des artères ou des veines.
US5372601A (en) 1993-03-30 1994-12-13 Lary; Banning G. Longitudinal reciprocating incisor
US5322508A (en) 1993-04-08 1994-06-21 Cordis Corporation Guidewire fluid delivery system and method of use
US5318528A (en) 1993-04-13 1994-06-07 Advanced Surgical Inc. Steerable surgical devices
US5429136A (en) 1993-04-21 1995-07-04 Devices For Vascular Intervention, Inc. Imaging atherectomy apparatus
US5716410A (en) 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
US5456667A (en) 1993-05-20 1995-10-10 Advanced Cardiovascular Systems, Inc. Temporary stenting catheter with one-piece expandable segment
WO1994027501A1 (en) 1993-05-24 1994-12-08 Boston Scientific Corporation Medical acoustic imaging catheter and guidewire
US5531685A (en) 1993-06-11 1996-07-02 Catheter Research, Inc. Steerable variable stiffness device
DE69416412T2 (de) 1993-07-03 1999-09-09 Medical Miracles Co. Ltd. Angioplastischer katheter mit führungsdraht
US5514115A (en) 1993-07-07 1996-05-07 Device For Vascular Intervention, Inc. Flexible housing for intracorporeal use
US5527325A (en) 1993-07-09 1996-06-18 Device For Vascular Intervention, Inc. Atherectomy catheter and method
US5419774A (en) 1993-07-13 1995-05-30 Scimed Life Systems, Inc. Thrombus extraction device
US5458585A (en) 1993-07-28 1995-10-17 Cardiovascular Imaging Systems, Inc. Tracking tip for a work element in a catheter system
US5395313A (en) 1993-08-13 1995-03-07 Naves; Neil H. Reciprocating arthroscopic shaver
US5441510A (en) 1993-09-01 1995-08-15 Technology Development Center Bi-axial cutter apparatus for catheter
US5573008A (en) 1993-10-29 1996-11-12 Boston Scientific Corporation Multiple biopsy sampling coring device
US5444078A (en) 1993-10-01 1995-08-22 Rohm And Haas Company Fully water-dilutable microemulsions
US5437645A (en) * 1993-10-08 1995-08-01 United States Surgical Corporation Surgical instrument positioning device
US5456689A (en) 1993-10-13 1995-10-10 Arnold J. Kresch Method and device for tissue resection
DE4335931B4 (de) 1993-10-21 2006-10-12 Cerasiv Gmbh Innovatives Keramik-Engineering Hüftgelenkpfanne
AU1091095A (en) 1993-11-08 1995-05-29 Harrison M. Lazarus Intraluminal vascular graft and method
US5507760A (en) 1993-11-09 1996-04-16 Devices For Vascular Intervention, Inc. Cutter device
US5443497A (en) 1993-11-22 1995-08-22 The Johns Hopkins University Percutaneous prosthetic by-pass graft and method of use
US5427107A (en) 1993-12-07 1995-06-27 Devices For Vascular Intervention, Inc. Optical encoder for catheter device
CA2160698A1 (en) 1993-12-09 1995-06-15 Charles Milo Composite drive shaft
US5503155A (en) 1994-01-26 1996-04-02 Cardiovascular Imaging Systems, Inc. Drive cable having internal lead wires
US5591127A (en) 1994-01-28 1997-01-07 Barwick, Jr.; Billie J. Phacoemulsification method and apparatus
US5507769A (en) 1994-10-18 1996-04-16 Stentco, Inc. Method and apparatus for forming an endoluminal bifurcated graft
US5413107A (en) 1994-02-16 1995-05-09 Tetrad Corporation Ultrasonic probe having articulated structure and rotatable transducer head
US5485840A (en) 1994-03-15 1996-01-23 Bauman; Robert P. Method of precise guidance for directional atherectomy using ultrasound
US5624457A (en) 1994-04-07 1997-04-29 Devices For Vascular Intervention Directional atherectomy device with flexible housing
US5569279A (en) 1994-04-29 1996-10-29 Rainin; Edgar A. Surgical abrading device
US5507795A (en) 1994-04-29 1996-04-16 Devices For Vascular Intervention, Inc. Catheter with perfusion system
US5466382A (en) 1994-05-03 1995-11-14 Rohm And Haas Company Synergistic microbicidal combinations containing 4,5-dichloro-2-n-octyl-3-isothiazolone and certain commercial biocides
USRE38335E1 (en) 1994-05-24 2003-11-25 Endius Incorporated Surgical instrument
US5628761A (en) 1994-07-08 1997-05-13 Rizik; David G. Guide wire passage creation device
US5531700A (en) 1994-07-29 1996-07-02 Cardiovascular Imaging Systems, Inc. Convertible tip catheters and sheaths
US5575817A (en) 1994-08-19 1996-11-19 Martin; Eric C. Aorto femoral bifurcation graft and method of implantation
US5609605A (en) 1994-08-25 1997-03-11 Ethicon, Inc. Combination arterial stent
WO1996010366A1 (en) 1994-10-03 1996-04-11 Heart Technology, Inc. Transluminal thrombectomy apparatus
US5571130A (en) 1994-10-04 1996-11-05 Advanced Cardiovascular Systems, Inc. Atherectomy and prostectomy system
US5491524A (en) 1994-10-05 1996-02-13 Carl Zeiss, Inc. Optical coherence tomography corneal mapping apparatus
US5512044A (en) 1994-10-11 1996-04-30 Duer; Edward Y. Embolic cutting catheter
US5549601A (en) 1994-10-11 1996-08-27 Devices For Vascular Intervention, Inc. Delivery of intracorporeal probes
US5507761A (en) 1994-10-11 1996-04-16 Duer; Edward Y. Embolic cutting catheter
US6032673A (en) 1994-10-13 2000-03-07 Femrx, Inc. Methods and devices for tissue removal
US5651771A (en) * 1994-11-07 1997-07-29 Applied Medical Resources Corporation Adjustable surgical clamp
AU3783295A (en) 1994-11-16 1996-05-23 Advanced Cardiovascular Systems Inc. Shape memory locking mechanism for intravascular stent
US5626562A (en) 1994-11-28 1997-05-06 Devices For Vascular Intervention Drug delivery catheter
DE4444166C2 (de) 1994-12-12 1998-09-24 Urotech Med Tech Gmbh Flexible Messervorrichtung für chirurgische Zwecke
US5643296A (en) 1994-12-16 1997-07-01 Devices For Vasclar Intervention Intravascular catheter with guiding structure
US5584843A (en) 1994-12-20 1996-12-17 Boston Scientific Corporation Shaped wire multi-burr rotational ablation device
US5836957A (en) 1994-12-22 1998-11-17 Devices For Vascular Intervention, Inc. Large volume atherectomy device
US5632754A (en) 1994-12-23 1997-05-27 Devices For Vascular Intervention Universal catheter with interchangeable work element
US6027450A (en) 1994-12-30 2000-02-22 Devices For Vascular Intervention Treating a totally or near totally occluded lumen
CA2157697C (en) 1995-01-10 2007-03-13 Banning Gray Lary Vascular incisor/dilator
US5700687A (en) 1995-01-30 1997-12-23 Bedminster Bioconversion Corporation Odor control system
US5683449A (en) 1995-02-24 1997-11-04 Marcade; Jean Paul Modular bifurcated intraluminal grafts and methods for delivering and assembling same
US5985397A (en) 1995-03-20 1999-11-16 Witt; Alvin E. Coated synthetic resin board tiles
US5876414A (en) 1995-03-28 1999-03-02 Straub Medical Ag Catheter for detaching abnormal deposits from blood vessels in humans
DK0817594T3 (da) 1995-03-28 2002-07-15 Straub Medical Ag Kateter til fjernelse af unormale aflejringer i humane blodkar
US5728123A (en) 1995-04-26 1998-03-17 Lemelson; Jerome H. Balloon actuated catheter
US5556408A (en) 1995-04-27 1996-09-17 Interventional Technologies Inc. Expandable and compressible atherectomy cutter
US5554163A (en) 1995-04-27 1996-09-10 Shturman Cardiology Systems, Inc. Atherectomy device
US5938645A (en) 1995-05-24 1999-08-17 Boston Scientific Corporation Northwest Technology Center Inc. Percutaneous aspiration catheter system
US5827229A (en) 1995-05-24 1998-10-27 Boston Scientific Corporation Northwest Technology Center, Inc. Percutaneous aspiration thrombectomy catheter system
US5618293A (en) 1995-06-06 1997-04-08 Smith & Nephews Dyonics, Inc. Surgical instrument
US5596990A (en) 1995-06-06 1997-01-28 Yock; Paul Rotational correlation of intravascular ultrasound image with guide catheter position
CA2223990C (en) 1995-06-07 2007-01-30 Cardima, Inc. Guiding catheter for coronary sinus
US5779673A (en) 1995-06-26 1998-07-14 Focal, Inc. Devices and methods for application of intraluminal photopolymerized gels
US5883458A (en) 1995-07-31 1999-03-16 Murata Manufacturing Co., Ltd. Terminal for a piezoelectric device
US5681336A (en) 1995-09-07 1997-10-28 Boston Scientific Corporation Therapeutic device for treating vien graft lesions
US6027460A (en) 1995-09-14 2000-02-22 Shturman Cardiology Systems, Inc. Rotatable intravascular apparatus
US5707383A (en) 1995-10-05 1998-01-13 Xomed Surgical Products, Inc. Method of removing soft tissue in the middle ear
IL124038A (en) 1995-10-13 2004-02-19 Transvascular Inc A device for bypassing arterial blockages and / or performing transcendental processes
KR19990064209A (ko) 1995-10-13 1999-07-26 트랜스바스큘라, 인코포레이티드 간질성 경혈관 개입을 위한 장치, 시스템 및 방법
US6375615B1 (en) 1995-10-13 2002-04-23 Transvascular, Inc. Tissue penetrating catheters having integral imaging transducers and their methods of use
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US6283983B1 (en) 1995-10-13 2001-09-04 Transvascular, Inc. Percutaneous in-situ coronary bypass method and apparatus
US6283951B1 (en) 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US5766192A (en) 1995-10-20 1998-06-16 Zacca; Nadim M. Atherectomy, angioplasty and stent method and apparatus
US5792112A (en) * 1995-10-20 1998-08-11 Applied Medical Resources Corporation Trocar with electrical discharge path
US5843022A (en) 1995-10-25 1998-12-01 Scimied Life Systems, Inc. Intravascular device utilizing fluid to extract occlusive material
US5989281A (en) 1995-11-07 1999-11-23 Embol-X, Inc. Cannula with associated filter and methods of use during cardiac surgery
US5868685A (en) 1995-11-14 1999-02-09 Devices For Vascular Intervention Articulated guidewire
US5697944A (en) 1995-11-15 1997-12-16 Interventional Technologies Inc. Universal dilator with expandable incisor
US5827304A (en) 1995-11-16 1998-10-27 Applied Medical Resources Corporation Intraluminal extraction catheter
US5688234A (en) 1996-01-26 1997-11-18 Cardiometrics Inc. Apparatus and method for the treatment of thrombotic occlusions in vessels
US5695506A (en) 1996-02-06 1997-12-09 Devices For Vascular Intervention Catheter device with a flexible housing
US5733296A (en) 1996-02-06 1998-03-31 Devices For Vascular Intervention Composite atherectomy cutter
JPH09215753A (ja) 1996-02-08 1997-08-19 Schneider Usa Inc チタン合金製自己拡張型ステント
US5800389A (en) 1996-02-09 1998-09-01 Emx, Inc. Biopsy device
US5709698A (en) 1996-02-26 1998-01-20 Linvatec Corporation Irrigating/aspirating shaver blade assembly
US6036707A (en) 1996-03-07 2000-03-14 Devices For Vascular Intervention Catheter device having a selectively flexible housing
US5830224A (en) 1996-03-15 1998-11-03 Beth Israel Deaconess Medical Center Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo
US5807329A (en) 1996-05-07 1998-09-15 Gelman; Martin L. Displaceable catheter device
RU2108119C1 (ru) * 1996-05-12 1998-04-10 Нижегородская государственная медицинская академия Устройство для ретроградной катетеризации левого желудочка у больных с аортальным стенозом крайней степени риска
US6152909A (en) 1996-05-20 2000-11-28 Percusurge, Inc. Aspiration system and method
US20010049517A1 (en) 1997-03-06 2001-12-06 Gholam-Reza Zadno-Azizi Method for containing and removing occlusions in the carotid arteries
US5709701A (en) 1996-05-30 1998-01-20 Parodi; Juan C. Apparatus for implanting a prothesis within a body passageway
US5779643A (en) 1996-11-26 1998-07-14 Hewlett-Packard Company Imaging guidewire with back and forth sweeping ultrasonic source
AU3378097A (en) 1996-06-07 1998-01-05 Scieran Technologies, Inc. An apparatus and method for performing ophthalmic procedures
US5843161A (en) 1996-06-26 1998-12-01 Cordis Corporation Endoprosthesis assembly for percutaneous deployment and method of deploying same
US5819738A (en) 1996-07-03 1998-10-13 Symbiosis Corporation Jaw assembly having progressively larger teeth and endoscopic biopsy forceps instrument incorporating same
US5820592A (en) 1996-07-16 1998-10-13 Hammerslag; Gary R. Angiographic and/or guide catheter
US5662671A (en) 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US5735816A (en) 1996-07-23 1998-04-07 Medtronic, Inc. Spiral sheath retainer for autoperfusion dilatation catheter balloon
US5972019A (en) 1996-07-25 1999-10-26 Target Therapeutics, Inc. Mechanical clot treatment device
US5827201A (en) 1996-07-26 1998-10-27 Target Therapeutics, Inc. Micro-braided guidewire
US6080170A (en) 1996-07-26 2000-06-27 Kensey Nash Corporation System and method of use for revascularizing stenotic bypass grafts and other occluded blood vessels
US5779721A (en) 1996-07-26 1998-07-14 Kensey Nash Corporation System and method of use for revascularizing stenotic bypass grafts and other blood vessels
US6830577B2 (en) 1996-07-26 2004-12-14 Kensey Nash Corporation System and method of use for treating occluded vessels and diseased tissue
US5676697A (en) 1996-07-29 1997-10-14 Cardiovascular Dynamics, Inc. Two-piece, bifurcated intraluminal graft for repair of aneurysm
US7603166B2 (en) 1996-09-20 2009-10-13 Board Of Regents University Of Texas System Method and apparatus for detection of vulnerable atherosclerotic plaque
JP2002515793A (ja) * 1996-10-23 2002-05-28 オーレイテック インターヴェンションズ インコーポレイテッド 椎間円板を治療するための方法及び装置
US6682536B2 (en) 2000-03-22 2004-01-27 Advanced Stent Technologies, Inc. Guidewire introducer sheath
US5713913A (en) 1996-11-12 1998-02-03 Interventional Technologies Inc. Device and method for transecting a coronary artery
US6217595B1 (en) 1996-11-18 2001-04-17 Shturman Cardiology Systems, Inc. Rotational atherectomy device
EP1011460A4 (en) 1996-12-02 2001-09-19 Angiotrax Inc APPARATUS AND METHODS SUITABLE FOR PERCUTANEOUS SURGERY
US5910150A (en) 1996-12-02 1999-06-08 Angiotrax, Inc. Apparatus for performing surgery
JP4200459B2 (ja) 1997-01-06 2008-12-24 二郎 北村 免震装置または免震構造
US5893857A (en) 1997-01-21 1999-04-13 Shturman Cardiology Systems, Inc. Handle for atherectomy device
US6129734A (en) 1997-01-21 2000-10-10 Shturman Cardiology Systems, Inc. Rotational atherectomy device with radially expandable prime mover coupling
DE19703779C2 (de) 1997-02-01 2003-06-05 Karlsruhe Forschzent Verfahren und Vorrichtung zur Herstellung eines dispersen Gemisches
US5720735A (en) 1997-02-12 1998-02-24 Dorros; Gerald Bifurcated endovascular catheter
JP2001512334A (ja) 1997-02-12 2001-08-21 プロリフィックス メディカル，インコーポレイテッド ステントから物質を除去する装置
US5882329A (en) 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US6217549B1 (en) 1997-02-28 2001-04-17 Lumend, Inc. Methods and apparatus for treating vascular occlusions
US6010449A (en) 1997-02-28 2000-01-04 Lumend, Inc. Intravascular catheter system for treating a vascular occlusion
US5741270A (en) 1997-02-28 1998-04-21 Lumend, Inc. Manual actuator for a catheter system for treating a vascular occlusion
US5968064A (en) 1997-02-28 1999-10-19 Lumend, Inc. Catheter system for treating a vascular occlusion
US6120516A (en) 1997-02-28 2000-09-19 Lumend, Inc. Method for treating vascular occlusion
US6849068B1 (en) 1997-03-06 2005-02-01 Medtronic Ave, Inc. Aspiration catheter
US5843103A (en) 1997-03-06 1998-12-01 Scimed Life Systems, Inc. Shaped wire rotational atherectomy device
US5824055A (en) 1997-03-25 1998-10-20 Endotex Interventional Systems, Inc. Stent graft delivery system and methods of use
US5772674A (en) 1997-03-31 1998-06-30 Nakhjavan; Fred K. Catheter for removal of clots in blood vessels
US5810867A (en) 1997-04-28 1998-09-22 Medtronic, Inc. Dilatation catheter with varied stiffness
US5911734A (en) 1997-05-08 1999-06-15 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
WO1998049953A1 (en) 1997-05-09 1998-11-12 Xomed Surgical Products, Inc. Angled rotary tissue cutting instrument
US6083207A (en) * 1998-12-08 2000-07-04 Daig Corporation Partitioned hemostasis valve system
US5954745A (en) 1997-05-16 1999-09-21 Gertler; Jonathan Catheter-filter set having a compliant seal
US6013072A (en) 1997-07-09 2000-01-11 Intraluminal Therapeutics, Inc. Systems and methods for steering a catheter through body tissue
US6048349A (en) 1997-07-09 2000-04-11 Intraluminal Therapeutics, Inc. Systems and methods for guiding a medical instrument through a body
EP1011856B1 (en) 1997-08-05 2003-04-09 Microfluidics International Corporation Multiple stream high pressure mixer/reactor
GB9717580D0 (en) 1997-08-19 1997-10-22 Curry Paul Device for opening blocked tubes
US6050949A (en) 1997-09-22 2000-04-18 Scimed Life Systems, Inc. Catheher system having connectable distal and proximal portions
US6361545B1 (en) 1997-09-26 2002-03-26 Cardeon Corporation Perfusion filter catheter
US5951480A (en) 1997-09-29 1999-09-14 Boston Scientific Corporation Ultrasound imaging guidewire with static central core and tip
US6066149A (en) 1997-09-30 2000-05-23 Target Therapeutics, Inc. Mechanical clot treatment device with distal filter
US6193676B1 (en) 1997-10-03 2001-02-27 Intraluminal Therapeutics, Inc. Guide wire assembly
US5951482A (en) 1997-10-03 1999-09-14 Intraluminal Therapeutics, Inc. Assemblies and methods for advancing a guide wire through body tissue
US6156046A (en) 1997-11-07 2000-12-05 Prolifix Medical, Inc. Methods and systems for treating obstructions in a body lumen
US5947985A (en) 1997-11-12 1999-09-07 Imran; Mir A. Apparatus and method for cleaning diseased vein grafts
US6183432B1 (en) 1997-11-13 2001-02-06 Lumend, Inc. Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip
US5938671A (en) 1997-11-14 1999-08-17 Reflow, Inc. Recanalization apparatus and devices for use therein and method
US5935108A (en) 1997-11-14 1999-08-10 Reflow, Inc. Recanalization apparatus and devices for use therein and method
US6330884B1 (en) 1997-11-14 2001-12-18 Transvascular, Inc. Deformable scaffolding multicellular stent
DE29722136U1 (de) 1997-12-15 1999-04-15 Ischinger, Thomas, Prof. Dr., 81927 München Vaskulärer Thrombektomiekatheter zur Entfernung von endoluminalem Thrombus
US6027514A (en) 1997-12-17 2000-02-22 Fox Hollow Technologies, Inc. Apparatus and method for removing occluding material from body lumens
US6217527B1 (en) 1998-09-30 2001-04-17 Lumend, Inc. Methods and apparatus for crossing vascular occlusions
US6231546B1 (en) 1998-01-13 2001-05-15 Lumend, Inc. Methods and apparatus for crossing total occlusions in blood vessels
US6081738A (en) 1998-01-15 2000-06-27 Lumend, Inc. Method and apparatus for the guided bypass of coronary occlusions
WO1999035977A1 (en) 1998-01-16 1999-07-22 Lumend, Inc. Catheter apparatus for treating arterial occlusions
US5865748A (en) 1998-01-16 1999-02-02 Guidant Corporation Guided directional coronary atherectomy distal linear encoder
US6280190B1 (en) * 1998-01-28 2001-08-28 Elliott S. Hoffman Dental saliva ejector tube assembly
JP2002502626A (ja) 1998-02-10 2002-01-29 アーテミス・メディカル・インコーポレイテッド 補足装置およびその使用方法
JP4157183B2 (ja) 1998-02-17 2008-09-24 オリンパス株式会社 内視鏡用処置具
US6159195A (en) 1998-02-19 2000-12-12 Percusurge, Inc. Exchange catheter and method of use
US20060074442A1 (en) 2000-04-06 2006-04-06 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses
US6398798B2 (en) 1998-02-28 2002-06-04 Lumend, Inc. Catheter system for treating a vascular occlusion
US6454727B1 (en) 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US6019778A (en) 1998-03-13 2000-02-01 Cordis Corporation Delivery apparatus for a self-expanding stent
US6561998B1 (en) 1998-04-07 2003-05-13 Transvascular, Inc. Transluminal devices, systems and methods for enlarging interstitial penetration tracts
US6001112A (en) 1998-04-10 1999-12-14 Endicor Medical, Inc. Rotational atherectomy device
US6482217B1 (en) 1998-04-10 2002-11-19 Endicor Medical, Inc. Neuro thrombectomy catheter
US6666874B2 (en) 1998-04-10 2003-12-23 Endicor Medical, Inc. Rotational atherectomy system with serrated cutting tip
US6383195B1 (en) 1998-04-13 2002-05-07 Endoline, Inc. Laparoscopic specimen removal apparatus
US6036646A (en) 1998-07-10 2000-03-14 Guided Therapy Systems, Inc. Method and apparatus for three dimensional ultrasound imaging
US6106515A (en) 1998-08-13 2000-08-22 Intraluminal Therapeutics, Inc. Expandable laser catheter
US6241744B1 (en) 1998-08-14 2001-06-05 Fox Hollow Technologies, Inc. Apparatus for deploying a guidewire across a complex lesion
US6095990A (en) 1998-08-31 2000-08-01 Parodi; Juan Carlos Guiding device and method for inserting and advancing catheters and guidewires into a vessel of a patient in endovascular treatments
US6022362A (en) 1998-09-03 2000-02-08 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6440147B1 (en) 1998-09-03 2002-08-27 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6620180B1 (en) 1998-09-09 2003-09-16 Medtronic Xomed, Inc. Powered laryngeal cutting blade
US6428551B1 (en) 1999-03-30 2002-08-06 Stereotaxis, Inc. Magnetically navigable and/or controllable device for removing material from body lumens and cavities
WO2000019917A1 (en) 1998-10-02 2000-04-13 Stereotaxis, Inc. Magnetically navigable and/or controllable device for removing material from body lumens and cavities
US6475222B1 (en) * 1998-11-06 2002-11-05 St. Jude Medical Atg, Inc. Minimally invasive revascularization apparatus and methods
US6264611B1 (en) 1998-11-25 2001-07-24 Ball Semiconductor, Inc. Monitor for interventional procedures
US6228076B1 (en) 1999-01-09 2001-05-08 Intraluminal Therapeutics, Inc. System and method for controlling tissue ablation
US6165199A (en) 1999-01-12 2000-12-26 Coaxia, Inc. Medical device for removing thromboembolic material from cerebral arteries and methods of use
US6191862B1 (en) 1999-01-20 2001-02-20 Lightlab Imaging, Llc Methods and apparatus for high speed longitudinal scanning in imaging systems
US6592526B1 (en) 1999-01-25 2003-07-15 Jay Alan Lenker Resolution ultrasound devices for imaging and treatment of body lumens
US6110121A (en) 1999-01-25 2000-08-29 Lenker; Jay Alan Method and apparatus for obtaining improved resolution from intraluminal ultrasound
US7524289B2 (en) 1999-01-25 2009-04-28 Lenker Jay A Resolution optical and ultrasound devices for imaging and treatment of body lumens
US6113615A (en) 1999-02-03 2000-09-05 Scimed Life Systems, Inc. Atherectomy burr including a bias wire
US6475226B1 (en) 1999-02-03 2002-11-05 Scimed Life Systems, Inc. Percutaneous bypass apparatus and method
AU763132B2 (en) 1999-02-04 2003-07-17 Antonio Carlos Netto Da Silva Branco Kit for endovascular venous surgery
JP2000225193A (ja) * 1999-02-08 2000-08-15 Clinical Supply:Kk カテーテル用閉塞具および該閉塞具を導入するための器具
US6544251B1 (en) * 1999-02-10 2003-04-08 Michael K. Crawford Peripherally inserted catheter
US6196963B1 (en) 1999-03-02 2001-03-06 Medtronic Ave, Inc. Brachytherapy device assembly and method of use
DE19911777A1 (de) 1999-03-17 2000-09-21 Merck Patent Gmbh Verfahren zur Herstellung von kosmetischen Formulierungen
US6245012B1 (en) 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6911026B1 (en) 1999-07-12 2005-06-28 Stereotaxis, Inc. Magnetically guided atherectomy
US6066153A (en) 1999-03-31 2000-05-23 Lev; Avigdor Device and method for resecting body tissues
US6277138B1 (en) 1999-08-17 2001-08-21 Scion Cardio-Vascular, Inc. Filter for embolic material mounted on expandable frame
US6319275B1 (en) 1999-04-07 2001-11-20 Medtronic Ave, Inc. Endolumenal prosthesis delivery assembly and method of use
DE19917148C2 (de) 1999-04-16 2002-01-10 Inst Mikrotechnik Mainz Gmbh Verfahren und Mikrovermischer zur Herstellung einer Dispersion
US7526481B1 (en) 1999-04-19 2009-04-28 Oracle International Corporation Web servers with queryable dynamic caches
US6790215B2 (en) 1999-04-30 2004-09-14 Edwards Lifesciences Corporation Method of use for percutaneous material removal device and tip
US6238405B1 (en) 1999-04-30 2001-05-29 Edwards Lifesciences Corp. Percutaneous material removal device and method
DE19920794A1 (de) 1999-05-06 2000-11-09 Merck Patent Gmbh Verfahren zur Herstellung von Perlpolymerisaten
DE19925184A1 (de) 1999-05-26 2000-11-30 Schering Ag Kontinuierliches Verfahren zur Herstellung von morphologisch einheitlichen Mikro- und Nanopartikeln mittels Mikromischer sowie nach diesem Verfahren hergestellte Partikel
US6126649A (en) 1999-06-10 2000-10-03 Transvascular, Inc. Steerable catheter with external guidewire as catheter tip deflector
US6605061B2 (en) * 1999-07-14 2003-08-12 Tricardia, L.L.C. Catheter for drug injection in cardiovascular system
US6179859B1 (en) 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US6142987A (en) 1999-08-03 2000-11-07 Scimed Life Systems, Inc. Guided filter with support wire and methods of use
US6445939B1 (en) 1999-08-09 2002-09-03 Lightlab Imaging, Llc Ultra-small optical probes, imaging optics, and methods for using same
US6231549B1 (en) 1999-08-17 2001-05-15 Sherwood Services, Ag Shim device for enteral feeding system
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7771444B2 (en) 2000-12-20 2010-08-10 Fox Hollow Technologies, Inc. Methods and devices for removing material from a body lumen
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US20030125757A1 (en) 2000-12-20 2003-07-03 Fox Hollow Technologies, Inc. Debulking catheters and methods
US6447525B2 (en) 1999-08-19 2002-09-10 Fox Hollow Technologies, Inc. Apparatus and methods for removing material from a body lumen
US20030120295A1 (en) 2000-12-20 2003-06-26 Fox Hollow Technologies, Inc. Debulking catheters and methods
US6638233B2 (en) 1999-08-19 2003-10-28 Fox Hollow Technologies, Inc. Apparatus and methods for material capture and removal
WO2001015609A1 (en) 1999-08-31 2001-03-08 Fox Hollow Technologies Atherectomy catheter with a rotating and telescoping cutter
US6187025B1 (en) 1999-09-09 2001-02-13 Noble-Met, Ltd. Vascular filter
WO2001019444A1 (en) 1999-09-17 2001-03-22 Bacchus Vascular Inc. Mechanical pump for removal of fragmented matter and methods of manufacture and use
US6533749B1 (en) 1999-09-24 2003-03-18 Medtronic Xomed, Inc. Angled rotary tissue cutting instrument with flexible inner member
EP1231969A1 (en) 1999-10-26 2002-08-21 Mark Wilson Ian Webster A guidewire positioning device
US6263236B1 (en) 1999-11-29 2001-07-17 Illumenex Corporation Non-occlusive expandable catheter
WO2001043809A1 (en) 1999-12-16 2001-06-21 Advanced Cardiovascular Systems, Inc. Catheter assembly and method for positioning the same at a bifurcated vessel
DE19961257C2 (de) 1999-12-18 2002-12-19 Inst Mikrotechnik Mainz Gmbh Mikrovermischer
US6394976B1 (en) 2000-01-31 2002-05-28 Intraluminal Therapeutics, Inc. Catheter for controlling the advancement of a guide wire
US6629953B1 (en) 2000-02-18 2003-10-07 Fox Hollow Technologies, Inc. Methods and devices for removing material from a vascular site
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US20010031981A1 (en) 2000-03-31 2001-10-18 Evans Michael A. Method and device for locating guidewire and treating chronic total occlusions
US6565588B1 (en) 2000-04-05 2003-05-20 Pathway Medical Technologies, Inc. Intralumenal material removal using an expandable cutting device
CA2403925C (en) 2000-04-05 2008-09-16 Stx Medical, Inc. Intralumenal material removal systems and methods
US7344546B2 (en) 2000-04-05 2008-03-18 Pathway Medical Technologies Intralumenal material removal using a cutting device for differential cutting
US6627784B2 (en) 2000-05-17 2003-09-30 Hydro Dynamics, Inc. Highly efficient method of mixing dissimilar fluids using mechanically induced cavitation
US6422736B1 (en) 2000-06-21 2002-07-23 Eastman Kodak Company Scalable impeller apparatus for preparing silver halide grains
US6532380B1 (en) 2000-06-30 2003-03-11 Cedars Sinai Medical Center Image guidance for coronary stent deployment
US6425870B1 (en) 2000-07-11 2002-07-30 Vermon Method and apparatus for a motorized multi-plane transducer tip
US6497711B1 (en) 2000-08-16 2002-12-24 Scimed Life Systems, Inc. Therectomy device having a light weight drive shaft and an imaging device
DE10041823C2 (de) 2000-08-25 2002-12-19 Inst Mikrotechnik Mainz Gmbh Verfahren und statischer Mikrovermischer zum Mischen mindestens zweier Fluide
US6656195B2 (en) 2000-09-22 2003-12-02 Medtronic Xomed, Inc. Flexible inner tubular members and rotary tissue cutting instruments having flexible inner tubular members
US20020058904A1 (en) 2000-11-08 2002-05-16 Robert Boock Thrombus removal device
AU2002235159A1 (en) 2000-12-05 2002-06-18 Lumend, Inc. Catheter system for vascular re-entry from a sub-intimal space
US20070049958A1 (en) 2005-08-30 2007-03-01 Arthrex, Inc. Spiral cut curved blade
EP1767159A1 (en) 2000-12-20 2007-03-28 Fox Hollow Technologies Inc. Catheter for removing atheromatous or thrombotic occlusive material
US20040167554A1 (en) 2000-12-20 2004-08-26 Fox Hollow Technologies, Inc. Methods and devices for reentering a true lumen from a subintimal space
US7699790B2 (en) * 2000-12-20 2010-04-20 Ev3, Inc. Debulking catheters and methods
US7169165B2 (en) 2001-01-16 2007-01-30 Boston Scientific Scimed, Inc. Rapid exchange sheath for deployment of medical devices and methods of use
US6569177B1 (en) 2001-01-19 2003-05-27 Scimed Life Systems, Inc. Ablation atherectomy burr
US6428552B1 (en) 2001-01-22 2002-08-06 Lumend, Inc. Method and apparatus for crossing intravascular occlusions
EP1420844A2 (en) 2001-04-16 2004-05-26 Medtronic Percusurge, Inc. Aspiration catheters and method of use
US20030023263A1 (en) 2001-07-24 2003-01-30 Incept Llc Apparatus and methods for aspirating emboli
US6623437B2 (en) 2001-08-28 2003-09-23 Rex Medical, L.P. Tissue biopsy apparatus
US6610059B1 (en) 2002-02-25 2003-08-26 Hs West Investments Llc Endoscopic instruments and methods for improved bubble aspiration at a surgical site
US20030199747A1 (en) 2002-04-19 2003-10-23 Michlitsch Kenneth J. Methods and apparatus for the identification and stabilization of vulnerable plaque
US6932502B2 (en) 2002-05-01 2005-08-23 Hewlett-Packard Development Company, L.P. Mixing apparatus
US7153315B2 (en) 2002-06-11 2006-12-26 Boston Scientific Scimed, Inc. Catheter balloon with ultrasonic microscalpel blades
CA2493356A1 (en) 2002-07-13 2004-01-22 Stryker Corporation System and method for performing irrigated nose and throat surgery
US20040210245A1 (en) 2002-07-26 2004-10-21 John Erickson Bendable needle with removable stylet
US20040049225A1 (en) 2002-09-11 2004-03-11 Denison Andy E. Aspiration catheter
US7734332B2 (en) 2002-10-18 2010-06-08 Ariomedica Ltd. Atherectomy system with imaging guidewire
US7815613B2 (en) * 2003-02-13 2010-10-19 Medical Components, Inc. Flexible conduit clamp
US7113093B2 (en) 2003-02-21 2006-09-26 Sensormatic Electronics Corporation Integrated electronic article surveillance (EAS) and point of sale (POS) system and method
US20040193034A1 (en) 2003-03-28 2004-09-30 Lawrence Wasicek Combined long rail/short rail IVUS catheter
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US20050004594A1 (en) 2003-07-02 2005-01-06 Jeffrey Nool Devices and methods for aspirating from filters
JP4026829B2 (ja) 2003-07-24 2007-12-26 ローム アンド ハース カンパニー 殺微生物組成物
JP2005068125A (ja) 2003-08-21 2005-03-17 Rohm & Haas Co 殺生物剤配合物の調製方法
US20050090849A1 (en) 2003-10-22 2005-04-28 Adams Kenneth M. Angled tissue cutting instruments and method of fabricating angled tissue cutting instrument having flexible inner tubular members of tube and single wrap construction
US7338495B2 (en) 2003-10-22 2008-03-04 Medtronic Xomed, Inc. Angled tissue cutting instruments having flexible inner tubular members of tube and sleeve construction
US20050090801A1 (en) * 2003-10-27 2005-04-28 Racz N. S. Safety spinal catheter
US7488322B2 (en) 2004-02-11 2009-02-10 Medtronic, Inc. High speed surgical cutting instrument
US7959634B2 (en) 2004-03-29 2011-06-14 Soteira Inc. Orthopedic surgery access devices
DE102004015639B4 (de) 2004-03-31 2007-05-03 Siemens Ag Vorrichtung zum Durchführen einer "Cutting-Balloon"-Intervention mit IVUS-Überwachung
US7104982B2 (en) * 2004-06-14 2006-09-12 Biosense Webster Inc Catheter grip
US7479148B2 (en) 2004-11-08 2009-01-20 Crescendo Technologies, Llc Ultrasonic shear with asymmetrical motion
US20060217687A1 (en) 2005-03-24 2006-09-28 Ethicon Endo-Surgery, Inc. Catheter-gripping device which measures insertion force during a medical procedure
WO2007002685A2 (en) 2005-06-24 2007-01-04 Volcano Corporation Co-registration of graphical image data representing three-dimensional vascular features
KR100668852B1 (ko) 2005-06-30 2007-01-16 주식회사 하이닉스반도체 듀티비 보정 장치
DE102005045373A1 (de) 2005-09-22 2007-04-05 Siemens Ag Kathetervorrichtung
US20080051812A1 (en) 2006-08-01 2008-02-28 Baxano, Inc. Multi-Wire Tissue Cutter
US20070167824A1 (en) 2005-11-30 2007-07-19 Warren Lee Method of manufacture of catheter tips, including mechanically scanning ultrasound probe catheter tip, and apparatus made by the method
DE102005059262B4 (de) 2005-12-12 2008-02-07 Siemens Ag Kathetervorrichtung
DE102005059271B4 (de) 2005-12-12 2019-02-21 Siemens Healthcare Gmbh Kathetervorrichtung
US7951161B2 (en) * 2006-05-09 2011-05-31 Medrad, Inc. Atherectomy system having a variably exposed cutter
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8361094B2 (en) 2006-06-30 2013-01-29 Atheromed, Inc. Atherectomy devices and methods
US8628549B2 (en) 2006-06-30 2014-01-14 Atheromed, Inc. Atherectomy devices, systems, and methods
US20090018566A1 (en) 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
US20080045986A1 (en) 2006-06-30 2008-02-21 Atheromed, Inc. Atherectomy devices and methods
US8920448B2 (en) 2006-06-30 2014-12-30 Atheromed, Inc. Atherectomy devices and methods
US8007506B2 (en) 2006-06-30 2011-08-30 Atheromed, Inc. Atherectomy devices and methods
JP4776032B2 (ja) 2006-07-26 2011-09-21 古河スカイ株式会社 熱交換器
AU2007303132B2 (en) 2006-10-04 2013-03-28 Boston Scientific Limited Interventional catheters
US7935144B2 (en) * 2006-10-19 2011-05-03 Direct Flow Medical, Inc. Profile reduction of valve implant
US8211025B2 (en) 2006-10-20 2012-07-03 General Electric Company Four-way steerable catheter system and method of use
US20080161840A1 (en) 2006-12-29 2008-07-03 Vascure Ltd. Atherectomy methods and apparatus
CA2675890A1 (en) 2007-01-19 2008-07-24 University Health Network Electrostatically driven imaging probe
US20080208227A1 (en) 2007-02-23 2008-08-28 Terumo Cardiovascular Systems Corporation Self-contained dissector/harvester device
US8574253B2 (en) 2007-04-06 2013-11-05 Hologic, Inc. Method, system and device for tissue removal
US20080312673A1 (en) 2007-06-05 2008-12-18 Viswanathan Raju R Method and apparatus for CTO crossing
US8475478B2 (en) 2007-07-05 2013-07-02 Cardiovascular Systems, Inc. Cleaning apparatus and method for high-speed rotational atherectomy devices
US8070762B2 (en) 2007-10-22 2011-12-06 Atheromed Inc. Atherectomy devices and methods
US8236016B2 (en) 2007-10-22 2012-08-07 Atheromed, Inc. Atherectomy devices and methods
US20090138031A1 (en) 2007-11-24 2009-05-28 Tsukernik Vladimir B Thrombectomy catheter with a helical cutter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
WO2009111670A1 (en) 2008-03-06 2009-09-11 Ev3 Endovascular, Inc. Image enhancement and application functionality for medical and other uses
US8062316B2 (en) 2008-04-23 2011-11-22 Avinger, Inc. Catheter system and method for boring through blocked vascular passages
US9498600B2 (en) 2009-07-01 2016-11-22 Avinger, Inc. Atherectomy catheter with laterally-displaceable tip
US20090275966A1 (en) 2008-05-05 2009-11-05 Miroslav Mitusina Flexible inner members having flexible regions comprising a plurality of intertwined helical cuts
US9186170B2 (en) 2008-06-05 2015-11-17 Cardiovascular Systems, Inc. Bidirectional expandable head for rotational atherectomy device
US20100030216A1 (en) 2008-07-30 2010-02-04 Arcenio Gregory B Discectomy tool having counter-rotating nucleus disruptors
JP5042162B2 (ja) 2008-08-12 2012-10-03 株式会社日立ハイテクノロジーズ 半導体加工方法
BRPI0920206A2 (pt) 2008-10-13 2015-12-22 Tyco Healthcare dispositivos e métodos para manipulação de um eixo de cateter
DE102009014489B4 (de) 2009-03-23 2011-03-10 Siemens Aktiengesellschaft Katheter und medizinische Vorrichtung
CN102625673B (zh) 2009-04-29 2014-12-24 泰科保健集团有限合伙公司 用于切割和研磨组织的方法及装置
EP2429423B1 (en) 2009-05-14 2015-11-11 Covidien LP Easily cleaned atherectomy catheters
US8142464B2 (en) 2009-07-21 2012-03-27 Miroslav Mitusina Flexible inner member having a flexible region composed of longitudinally and rotationally offset partial circumferential cuts
WO2011040250A1 (ja) 2009-09-29 2011-04-07 コニカミノルタホールディングス株式会社 アクチュエータ、駆動装置、およびカメラモジュール
WO2011068932A1 (en) 2009-12-02 2011-06-09 Fox Hollow Technologies, Inc. Methods and devices for cutting tissue
CA2783301C (en) 2009-12-11 2015-02-24 Tyco Healthcare Group Lp Material removal device having improved material capture efficiency and methods of use
JP6269460B2 (ja) 2014-12-10 2018-01-31 京セラドキュメントソリューションズ株式会社 画像形成装置

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108368715A (zh) * 2015-10-19 2018-08-03 伊利诺斯工具制品有限公司 包含双铰接声音衰减折片特征的门把手
CN108368715B (zh) * 2015-10-19 2020-03-13 伊利诺斯工具制品有限公司 包含双铰接声音衰减折片特征的门把手
US11293204B2 (en) 2015-10-19 2022-04-05 Illinois Tool Works Inc. Door handle including dual hinged sound dampening flap feature
CN109069180A (zh) * 2016-04-14 2018-12-21 柯惠有限合伙公司 具有调节机构的组织去除导管
CN109069181A (zh) * 2016-04-27 2018-12-21 柯惠有限合伙公司 包括用于旋转和往复运动组织去除元件的驱动组件的导管
CN109069181B (zh) * 2016-04-27 2021-06-25 柯惠有限合伙公司 包括用于旋转和往复运动组织去除元件的驱动组件的导管
CN110944750A (zh) * 2017-05-17 2020-03-31 拜欧迪克斯公司 人体工学流体处理管
CN110944750B (zh) * 2017-05-17 2022-01-28 拜欧迪克斯公司 人体工学流体处理管
US11433391B2 (en) 2017-05-17 2022-09-06 Biotix, Inc. Ergonomic fluid handling tubes
CN114470487A (zh) * 2021-12-22 2022-05-13 广东博迈医疗科技股份有限公司 医用导丝及介入医疗设备
CN114470487B (zh) * 2021-12-22 2023-02-14 广东博迈医疗科技股份有限公司 医用导丝及介入医疗设备

Also Published As

Publication number Publication date
AU2009303501B2 (en) 2013-11-21
KR101645754B1 (ko) 2016-08-04
WO2010045226A2 (en) 2010-04-22
US20140107679A1 (en) 2014-04-17
US8414604B2 (en) 2013-04-09
WO2010045226A3 (en) 2010-06-24
US9192406B2 (en) 2015-11-24
JP5555242B2 (ja) 2014-07-23
JP2014057893A (ja) 2014-04-03
RU2503422C2 (ru) 2014-01-10
JP5793178B2 (ja) 2015-10-14
CA2739665A1 (en) 2010-04-20
JP2012505060A (ja) 2012-03-01
US20160038175A1 (en) 2016-02-11
CA2739665C (en) 2018-01-02
AU2009303501A1 (en) 2010-04-22
RU2011113992A (ru) 2012-11-20
BRPI0920206A2 (pt) 2015-12-22
US10507037B2 (en) 2019-12-17
CN102223847B (zh) 2013-10-30
EP2358282A2 (en) 2011-08-24
KR20110079898A (ko) 2011-07-11
EP2358282B1 (en) 2017-12-06
US20100130996A1 (en) 2010-05-27
EP3275383A1 (en) 2018-01-31

Similar Documents

Publication Publication Date Title
CN102223847B (zh) 用于操纵导管轴的装置和方法
EP1667588B1 (en) Medical retrieval devices
US5782834A (en) Surgical instrument
CN101370440B (zh) 凝固切开装置
KR101452614B1 (ko) 물질 제거 장치 및 사용 방법
JP6181167B2 (ja) 調整可能なチップを有するフレキシブルプローブ
US20120053595A1 (en) Endoscopic Instrument with Rotational and Axial Motion Control
WO2001010321A1 (en) Polypectomy snare instrument
US10765441B2 (en) Devices for medical procedures and related methods of use
JP4542362B2 (ja) 内視鏡処置システム
CN114376654A (zh) 可弯曲的夹装置
CN116234509A (zh) 医疗铰接装置和使用其的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant