CN101621989A - 用于局部鼻施用的奥洛他定制剂 - Google Patents

用于局部鼻施用的奥洛他定制剂 Download PDF

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Publication number
CN101621989A
CN101621989A CN200780051017A CN200780051017A CN101621989A CN 101621989 A CN101621989 A CN 101621989A CN 200780051017 A CN200780051017 A CN 200780051017A CN 200780051017 A CN200780051017 A CN 200780051017A CN 101621989 A CN101621989 A CN 101621989A
Authority
CN
China
Prior art keywords
olopatadine
compositions
phosphate
amount
nacl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200780051017A
Other languages
English (en)
Chinese (zh)
Inventor
O·N·辛格
G·M·华尔
R·贾尼
M·A·乔罕
W·W·韩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Alcon Universal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Universal Ltd filed Critical Alcon Universal Ltd
Publication of CN101621989A publication Critical patent/CN101621989A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200780051017A 2007-02-07 2007-02-07 用于局部鼻施用的奥洛他定制剂 Pending CN101621989A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/003285 WO2008097220A1 (en) 2007-02-07 2007-02-07 Olopatadine formulations for topical nasal administration

Publications (1)

Publication Number Publication Date
CN101621989A true CN101621989A (zh) 2010-01-06

Family

ID=38542957

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200780051017A Pending CN101621989A (zh) 2007-02-07 2007-02-07 用于局部鼻施用的奥洛他定制剂

Country Status (16)

Country Link
EP (2) EP2977042B1 (de)
JP (1) JP5149308B2 (de)
KR (1) KR20100014858A (de)
CN (1) CN101621989A (de)
AU (1) AU2007346121B2 (de)
BR (1) BRPI0721255B8 (de)
CA (1) CA2677631C (de)
DK (1) DK2114367T3 (de)
ES (2) ES2557939T3 (de)
HK (1) HK1217090A1 (de)
HU (1) HUE026162T2 (de)
MX (1) MX2009008548A (de)
PL (1) PL2114367T3 (de)
PT (1) PT2114367E (de)
SI (1) SI2114367T1 (de)
WO (1) WO2008097220A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830219A (zh) * 2012-11-20 2014-06-04 深圳大佛药业有限公司 一种稳定的奥洛他定组合物
CN114980881A (zh) * 2019-12-06 2022-08-30 东兴药品工业株式会社 包含奥洛他定的鼻用组合物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011001317A (ja) * 2009-06-19 2011-01-06 Fumakilla Ltd 鼻用洗浄剤
MX2012000539A (es) * 2009-07-17 2012-02-28 Alcon Res Ltd Regimen de rocio nasal de olopatadina para niños.
KR101271925B1 (ko) * 2011-02-10 2013-06-05 비. 김 로버트 미네랄 알칼리수
TW201336527A (zh) * 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8520662D0 (en) 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
US4923892A (en) 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
JPS6310784A (ja) 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
JP3662944B2 (ja) * 1993-08-24 2005-06-22 協和醗酵工業株式会社 点鼻剤
US5641805A (en) 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
AU776789B2 (en) * 2000-01-25 2004-09-23 Alcon Inc. Ophthalmic anti-allergy compositions suitable for use with contact lenses
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
CA2504200A1 (en) * 2002-11-12 2004-05-27 Alcon, Inc. The use of an anti-allergy agent and a steroid to treat allergic rhinitis
DK1814538T3 (da) 2004-11-24 2009-11-02 Alcon Inc Fremgangsmåde til administration af næsespray

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830219A (zh) * 2012-11-20 2014-06-04 深圳大佛药业有限公司 一种稳定的奥洛他定组合物
CN114980881A (zh) * 2019-12-06 2022-08-30 东兴药品工业株式会社 包含奥洛他定的鼻用组合物

Also Published As

Publication number Publication date
PL2114367T3 (pl) 2016-03-31
SI2114367T1 (sl) 2016-01-29
EP2114367B1 (de) 2015-11-04
KR20100014858A (ko) 2010-02-11
JP2010518075A (ja) 2010-05-27
ES2781090T3 (es) 2020-08-28
ES2557939T3 (es) 2016-01-29
HK1217090A1 (zh) 2016-12-23
AU2007346121B2 (en) 2012-08-23
HUE026162T2 (en) 2016-05-30
PT2114367E (pt) 2016-02-01
BRPI0721255B1 (pt) 2019-08-27
CA2677631C (en) 2014-05-13
DK2114367T3 (en) 2015-12-07
MX2009008548A (es) 2009-08-18
EP2114367A1 (de) 2009-11-11
WO2008097220A1 (en) 2008-08-14
BRPI0721255A2 (pt) 2013-01-01
EP2977042A1 (de) 2016-01-27
BRPI0721255B8 (pt) 2021-05-25
EP2977042B1 (de) 2020-01-01
JP5149308B2 (ja) 2013-02-20
AU2007346121A1 (en) 2008-08-14
CA2677631A1 (en) 2008-08-14

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Open date: 20100106