CN101541977A - 用于raf抑制剂的靶向调节、效力、诊断和/或预后的生物标志物 - Google Patents
用于raf抑制剂的靶向调节、效力、诊断和/或预后的生物标志物 Download PDFInfo
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- CN101541977A CN101541977A CNA2007800426892A CN200780042689A CN101541977A CN 101541977 A CN101541977 A CN 101541977A CN A2007800426892 A CNA2007800426892 A CN A2007800426892A CN 200780042689 A CN200780042689 A CN 200780042689A CN 101541977 A CN101541977 A CN 101541977A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84560106P | 2006-09-19 | 2006-09-19 | |
| US60/845,601 | 2006-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101541977A true CN101541977A (zh) | 2009-09-23 |
Family
ID=39445772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007800426892A Pending CN101541977A (zh) | 2006-09-19 | 2007-09-19 | 用于raf抑制剂的靶向调节、效力、诊断和/或预后的生物标志物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100004253A1 (enExample) |
| EP (1) | EP2074226A2 (enExample) |
| JP (2) | JP2010504530A (enExample) |
| KR (1) | KR20090071603A (enExample) |
| CN (1) | CN101541977A (enExample) |
| AU (1) | AU2007340265B2 (enExample) |
| BR (1) | BRPI0716944A2 (enExample) |
| CA (1) | CA2662508A1 (enExample) |
| IL (1) | IL197450A0 (enExample) |
| MX (1) | MX2009002936A (enExample) |
| RU (1) | RU2009114745A (enExample) |
| SG (1) | SG174826A1 (enExample) |
| WO (1) | WO2008082730A2 (enExample) |
Cited By (65)
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| WO2013104104A1 (zh) * | 2012-01-09 | 2013-07-18 | 苏州工业园区为真生物医药科技有限公司 | 诊断和预示乳腺癌的标志物 |
| CN103608683A (zh) * | 2011-06-02 | 2014-02-26 | 诺华股份有限公司 | Hedgehog抑制剂治疗的生物标志物 |
| CN103941016A (zh) * | 2013-05-07 | 2014-07-23 | 上海良润生物医药科技有限公司 | 半胱氨酸蛋白酶抑制剂sn与癌胚抗原的联合应用 |
| CN104502603A (zh) * | 2014-12-03 | 2015-04-08 | 上海交通大学医学院附属上海儿童医学中心 | Myo1d作为诊断动脉导管闭合或开放的标志物 |
| CN105126080A (zh) * | 2015-09-29 | 2015-12-09 | 武汉大学 | 锌指蛋白436(znf436)在治疗心肌肥厚中的应用 |
| CN105659085A (zh) * | 2013-08-28 | 2016-06-08 | 中美冠科生物技术(太仓)有限公司 | 预测受试者对多激酶抑制剂的反应的基因表达标志及其使用方法 |
| CN105671158A (zh) * | 2016-02-29 | 2016-06-15 | 北京泱深生物信息技术有限公司 | Fam63b基因在制备诊治子宫肌瘤的产品中的用途 |
| CN105695617A (zh) * | 2016-04-22 | 2016-06-22 | 王冬国 | 乳头状癌的肿瘤标志物及其应用 |
| CN105986023A (zh) * | 2015-02-17 | 2016-10-05 | 上海交通大学医学院附属上海儿童医学中心 | 急性淋巴细胞白血病耐药复发相关突变基因及其应用 |
| CN106104273A (zh) * | 2013-12-12 | 2016-11-09 | 施特姆森特克斯股份有限公司 | 新型抗dpep3抗体和使用方法 |
| CN107075569A (zh) * | 2014-05-07 | 2017-08-18 | 英国卫生部 | 用于诊断结核病的生物标记物及其组合 |
| WO2018129988A1 (zh) * | 2017-01-11 | 2018-07-19 | 上海易毕恩基因科技有限公司 | 用于检测肠癌的基因标志物的方法、用该方法筛选的基因标志物及其用途 |
| CN108624678A (zh) * | 2018-06-26 | 2018-10-09 | 北京泱深生物信息技术有限公司 | 一种用于子痫前期诊治的生物标志物 |
| CN108676867A (zh) * | 2018-06-06 | 2018-10-19 | 北京泱深生物信息技术有限公司 | 诊治子痫前期的vwce基因及其应用 |
| CN108707628A (zh) * | 2018-05-28 | 2018-10-26 | 上海海洋大学 | 斑马鱼notch2基因突变体的制备方法 |
| CN108753834A (zh) * | 2018-05-28 | 2018-11-06 | 上海海洋大学 | ddx27基因缺失斑马鱼突变体的制备方法 |
| CN108841960A (zh) * | 2018-07-12 | 2018-11-20 | 吉林大学 | 一种结肠腺癌易感性预测试剂盒及系统 |
| CN109081866A (zh) * | 2017-06-13 | 2018-12-25 | 北京大学 | 癌症中的t细胞亚群及其特征基因 |
| CN109414448A (zh) * | 2016-06-17 | 2019-03-01 | 豪夫迈·罗氏有限公司 | 用于减少PAPD5或PAPD7 mRNA治疗乙型肝炎感染的核酸分子 |
| CN109468320A (zh) * | 2018-11-13 | 2019-03-15 | 复旦大学附属中山医院 | 一种环状rna及其在肝癌诊断中的应用 |
| CN109825508A (zh) * | 2017-11-23 | 2019-05-31 | 深圳市第三人民医院 | 一种用来评估艾滋病合并结核感染的生物标记物 |
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| CN110072526A (zh) * | 2016-08-17 | 2019-07-30 | 西奈山伊坎医学院 | 治疗癌症的激酶抑制剂化合物、组合物和方法 |
| CN110408706A (zh) * | 2019-08-30 | 2019-11-05 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 一种评估鼻咽癌复发的生物标志物及其应用 |
| CN110551819A (zh) * | 2019-08-23 | 2019-12-10 | 伯克利南京医学研究有限责任公司 | 一组卵巢癌预后相关基因的应用 |
| CN110643571A (zh) * | 2019-10-22 | 2020-01-03 | 康妍葆(北京)干细胞科技有限公司 | 人角蛋白6a在干细胞培养中的应用及产品 |
| CN110819714A (zh) * | 2019-11-22 | 2020-02-21 | 南方医科大学深圳医院 | 一种抑癌基因及其应用 |
| CN110914457A (zh) * | 2017-03-15 | 2020-03-24 | 卫材研究发展管理有限公司 | 剪接体突变及其用途 |
| WO2020151697A1 (zh) * | 2019-01-23 | 2020-07-30 | 首都师范大学 | 人rev3l蛋白翻译后切割所依赖的序列元件及其应用 |
| CN111781358A (zh) * | 2020-07-13 | 2020-10-16 | 张瑜 | Xab2蛋白作为卵巢癌预后和/或预测铂类耐药标志物 |
| CN111896740A (zh) * | 2019-05-06 | 2020-11-06 | 山东大学 | 诊断或预测生育缺陷的方法和试剂盒 |
| CN112153983A (zh) * | 2018-05-23 | 2020-12-29 | 杰克逊实验室 | 抗ngly-1抗体及使用方法 |
| CN112691195A (zh) * | 2021-02-02 | 2021-04-23 | 黑龙江省科学院高技术研究院 | Prpf8表达抑制剂在制备治疗肺癌的药物中的应用 |
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| WO2009158620A2 (en) * | 2008-06-26 | 2009-12-30 | Dana-Farber Cancer Institute, Inc. | Signatures and determinants associated with metastasis methods of use thereof |
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| BRPI0921043A2 (pt) | 2008-11-12 | 2018-08-07 | Caris Life Sciences Luxembourg Holdings | métodos e sistemas para usar exossomas para determinar fenótipos |
| US20120041274A1 (en) * | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| CN105906631A (zh) * | 2009-11-18 | 2016-08-31 | 普莱希科公司 | 用于激酶调节的化合物和方法及其适应症 |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
| AU2011223789A1 (en) | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2009002936A (es) | 2009-04-01 |
| CA2662508A1 (en) | 2008-07-10 |
| RU2009114745A (ru) | 2010-10-27 |
| WO2008082730A3 (en) | 2009-01-08 |
| IL197450A0 (en) | 2009-12-24 |
| JP2013128487A (ja) | 2013-07-04 |
| AU2007340265A1 (en) | 2008-07-10 |
| SG174826A1 (en) | 2011-10-28 |
| JP2010504530A (ja) | 2010-02-12 |
| KR20090071603A (ko) | 2009-07-01 |
| BRPI0716944A2 (pt) | 2013-09-17 |
| EP2074226A2 (en) | 2009-07-01 |
| WO2008082730A2 (en) | 2008-07-10 |
| AU2007340265B2 (en) | 2012-07-26 |
| US20100004253A1 (en) | 2010-01-07 |
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