CN101511391B - N末端聚唾液酸化 - Google Patents

N末端聚唾液酸化 Download PDF

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CN101511391B
CN101511391B CN2007800337418A CN200780033741A CN101511391B CN 101511391 B CN101511391 B CN 101511391B CN 2007800337418 A CN2007800337418 A CN 2007800337418A CN 200780033741 A CN200780033741 A CN 200780033741A CN 101511391 B CN101511391 B CN 101511391B
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insulin
polysaccharide
protein
composition according
chain
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CN101511391A (zh
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S·杰因
张荣升
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Lipoxen Technologies Ltd
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Lipoxen Technologies Ltd
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C12N9/14—Hydrolases (3)
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CN2007800337418A 2006-07-25 2007-07-25 N末端聚唾液酸化 Expired - Fee Related CN101511391B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06117830 2006-07-25
EP06117830.7 2006-07-25
PCT/GB2007/002821 WO2008012528A1 (en) 2006-07-25 2007-07-25 N-terminal polysialylation

Related Child Applications (1)

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CN201310022631.9A Division CN103169984B (zh) 2006-07-25 2007-07-25 N末端聚唾液酸化

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CN101511391A CN101511391A (zh) 2009-08-19
CN101511391B true CN101511391B (zh) 2013-03-13

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CN201310022631.9A Expired - Fee Related CN103169984B (zh) 2006-07-25 2007-07-25 N末端聚唾液酸化

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US (22) US10300144B2 (enExample)
EP (6) EP3299033A1 (enExample)
JP (14) JP5096466B2 (enExample)
KR (1) KR101400105B1 (enExample)
CN (2) CN101511391B (enExample)
AT (1) ATE467642T1 (enExample)
DE (1) DE602007006492D1 (enExample)
ES (5) ES2581902T3 (enExample)
RU (1) RU2432175C2 (enExample)
WO (4) WO2008012528A1 (enExample)

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