CN101466823A - 培养物观察系统 - Google Patents
培养物观察系统 Download PDFInfo
- Publication number
- CN101466823A CN101466823A CNA2007800217986A CN200780021798A CN101466823A CN 101466823 A CN101466823 A CN 101466823A CN A2007800217986 A CNA2007800217986 A CN A2007800217986A CN 200780021798 A CN200780021798 A CN 200780021798A CN 101466823 A CN101466823 A CN 101466823A
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- culturing room
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- plummer
- monitoring system
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- 238000012544 monitoring process Methods 0.000 title claims abstract description 28
- 238000012258 culturing Methods 0.000 claims abstract description 71
- 230000007246 mechanism Effects 0.000 claims description 12
- 230000008520 organization Effects 0.000 claims description 5
- 230000005540 biological transmission Effects 0.000 claims description 4
- 238000003384 imaging method Methods 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 description 71
- 239000007789 gas Substances 0.000 description 47
- 230000033001 locomotion Effects 0.000 description 18
- 238000009413 insulation Methods 0.000 description 10
- 230000008859 change Effects 0.000 description 9
- 230000006870 function Effects 0.000 description 6
- 238000005192 partition Methods 0.000 description 6
- 210000004748 cultured cell Anatomy 0.000 description 4
- 238000004113 cell culture Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000004590 computer program Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000386 microscopy Methods 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000003995 blood forming stem cell Anatomy 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 210000001671 embryonic stem cell Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003760 hair shine Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 210000001178 neural stem cell Anatomy 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
- C12M1/38—Temperature-responsive control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/14—Incubators; Climatic chambers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
Abstract
Description
Claims (2)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP167725/2006 | 2006-06-16 | ||
JP2006167725 | 2006-06-16 | ||
PCT/JP2007/061790 WO2007145198A1 (ja) | 2006-06-16 | 2007-06-12 | 培養物観察システム |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101466823A true CN101466823A (zh) | 2009-06-24 |
CN101466823B CN101466823B (zh) | 2013-04-03 |
Family
ID=38831713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007800217986A Expired - Fee Related CN101466823B (zh) | 2006-06-16 | 2007-06-12 | 培养物观察系统 |
Country Status (6)
Country | Link |
---|---|
US (1) | US8455241B2 (zh) |
EP (1) | EP2031051B1 (zh) |
JP (3) | JP5841304B2 (zh) |
KR (1) | KR101378204B1 (zh) |
CN (1) | CN101466823B (zh) |
WO (1) | WO2007145198A1 (zh) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102289066A (zh) * | 2011-08-12 | 2011-12-21 | 北京航空航天大学 | 一种多细胞培养过程自动显微成像系统 |
CN102762713A (zh) * | 2010-01-20 | 2012-10-31 | Emd密理博公司 | 细胞图像捕捉和远程监控系统 |
CN102827758A (zh) * | 2012-09-24 | 2012-12-19 | 长春理工大学 | 细胞工厂中细胞显微观察监测仪 |
CN104774906A (zh) * | 2015-04-24 | 2015-07-15 | 南京爱贝生物科技有限公司 | 一种活细胞连续观察方法 |
CN105586259A (zh) * | 2016-01-20 | 2016-05-18 | 中国科学院广州生物医药与健康研究院 | 细胞培养中细胞图像获取装置的控制系统及控制方法 |
CN107034131A (zh) * | 2015-11-05 | 2017-08-11 | 奥林巴斯株式会社 | 观察装置以及观察方法 |
CN107151627A (zh) * | 2016-03-03 | 2017-09-12 | 奥林巴斯株式会社 | 观察装置、测定系统、观察方法以及记录介质 |
CN107227258A (zh) * | 2016-03-23 | 2017-10-03 | 奥林巴斯株式会社 | 观察装置及其控制方法、测定系统、培养容器、记录介质 |
CN110452819A (zh) * | 2019-07-29 | 2019-11-15 | 西安医学院 | 一种可观测的低压低氧细胞培养箱 |
CN110747115A (zh) * | 2019-11-19 | 2020-02-04 | 长春理工大学 | 细胞工厂生物反应器显微光电监测系统 |
CN111486891A (zh) * | 2019-01-29 | 2020-08-04 | 株式会社岛津制作所 | 摄像环境测定器以及摄像环境测定系统 |
USD907244S1 (en) | 2019-06-14 | 2021-01-05 | Emd Millipore Corporation | Cell imager |
CN115948243A (zh) * | 2022-09-30 | 2023-04-11 | 河北医科大学第二医院 | 一种高内涵专用低氧工作站 |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101331500B (zh) | 2005-10-14 | 2015-04-29 | 尤尼森斯繁殖技术公司 | 细胞群的变化的测定 |
EP2031051B1 (en) * | 2006-06-16 | 2021-05-19 | PHC Holdings Corporation | Culture monitoring system |
CN101802166B (zh) | 2007-06-29 | 2013-12-11 | 尤尼森斯繁殖技术公司 | 用于监测和/或培养显微对象的设备、系统和方法 |
JP5097618B2 (ja) * | 2008-05-29 | 2012-12-12 | 三洋電機株式会社 | インキュベータ |
JP5430949B2 (ja) * | 2009-01-13 | 2014-03-05 | 公立大学法人公立はこだて未来大学 | 微生物検査システム |
KR101102300B1 (ko) * | 2009-06-19 | 2012-01-03 | 전자부품연구원 | 세포 관찰 장치 |
CN102471749B (zh) | 2009-07-08 | 2014-01-08 | 株式会社尼康 | 细胞采集辅助装置、显示装置及培养容器 |
KR101352639B1 (ko) * | 2011-12-30 | 2014-01-17 | 광주과학기술원 | 세포 배양 관찰 장치 |
KR101505874B1 (ko) * | 2012-12-05 | 2015-03-25 | (주)옵토레인 | 온 칩 세포배양 관찰장치 및 온 칩 세포배양 관찰키트 |
CN104181932B (zh) * | 2013-05-21 | 2017-09-22 | 台达电子工业股份有限公司 | 限位装置及控制方法 |
DK3090040T3 (da) * | 2014-01-03 | 2020-01-27 | Copan Italia Spa | Apparat og fremgangsmåde til behandling af diagnostisk information relateret til prøver af mikrobiologisk materiale |
WO2016158337A1 (ja) | 2015-03-30 | 2016-10-06 | パナソニックヘルスケアホールディングス株式会社 | 培養装置 |
JP6906992B2 (ja) * | 2017-03-24 | 2021-07-21 | オリンパス株式会社 | 表示制御システム、表示制御方法、及び、プログラム |
JPWO2018229920A1 (ja) * | 2017-06-15 | 2020-04-16 | オリンパス株式会社 | 定量評価装置 |
WO2019003271A1 (ja) * | 2017-06-26 | 2019-01-03 | オリンパス株式会社 | 細胞観察システム |
US20200319217A1 (en) * | 2019-04-08 | 2020-10-08 | Molecular Devices, Llc | Incubation System and Method for Automated Cell Culture and Testing |
SE2050382A1 (en) * | 2020-04-03 | 2021-10-04 | Cellink Ab | A cell monitoring device for use inside a humid incubator and a humid incubator system |
CN114276918A (zh) * | 2021-12-13 | 2022-04-05 | 余珏玲 | 一种微生物培养用柜 |
CN115404166A (zh) * | 2022-10-10 | 2022-11-29 | 北京北美抗衰老医学研究院 | 一种新型脂肪干细胞外泌体培养装置 |
Family Cites Families (33)
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JPS60137279A (ja) * | 1983-12-26 | 1985-07-20 | Olympus Optical Co Ltd | 培養装置における観察装置 |
US4629862A (en) * | 1984-03-28 | 1986-12-16 | Olympus Optical Company Ltd. | Sample heater for use in microscopes |
JPS60156521U (ja) * | 1984-03-29 | 1985-10-18 | オリンパス光学工業株式会社 | 顕微鏡の試料保温装置 |
JPS60156996U (ja) * | 1984-03-28 | 1985-10-18 | オリンパス光学工業株式会社 | 顕微鏡観察のための培養装置 |
FR2567538B1 (fr) * | 1984-07-12 | 1986-12-26 | Inst Nat Sante Rech Med | Automate pour l'analyse et le clonage de cultures cellulaires ainsi que pour l'analyse bacteriologique |
JPH0325599Y2 (zh) * | 1985-03-19 | 1991-06-03 | ||
JPS62137279A (ja) * | 1985-12-09 | 1987-06-20 | Daihatsu Motor Co Ltd | 四輪操舵装置 |
JPH0423978A (ja) * | 1990-05-17 | 1992-01-28 | Sanyo Electric Co Ltd | 培養装置 |
JPH05227942A (ja) * | 1992-02-25 | 1993-09-07 | Unie Data:Kk | 培養装置 |
JPH08285777A (ja) | 1995-04-12 | 1996-11-01 | Hamamatsu Photonics Kk | 微弱光測定装置 |
US5922593A (en) * | 1997-05-23 | 1999-07-13 | Becton, Dickinson And Company | Microbiological test panel and method therefor |
US6597450B1 (en) * | 1997-09-15 | 2003-07-22 | Becton, Dickinson And Company | Automated Optical Reader for Nucleic Acid Assays |
US6228636B1 (en) * | 1998-09-21 | 2001-05-08 | Matsushita Electric Industrial Co., Ltd. | Incubator |
US6271022B1 (en) * | 1999-03-12 | 2001-08-07 | Biolog, Inc. | Device for incubating and monitoring multiwell assays |
EP1169614A1 (en) * | 1999-04-01 | 2002-01-09 | Brian Emile Montaut | A method and apparatus for facilitating a determination of a linear dimension of an object from an image of the object |
US6849422B1 (en) * | 2000-05-31 | 2005-02-01 | Becton, Dickinson And Company | System and method for analyzing antibiotic susceptibility of biological samples using redox and turbidity measurments to ascertain minimum inhibitory concentrations (MICs) |
JP4535645B2 (ja) * | 2001-07-06 | 2010-09-01 | 株式会社 ジャパン・ティッシュ・エンジニアリング | 接着細胞選別装置、細胞増殖能評価装置、それらのプログラム及びそれらの方法 |
JP4044375B2 (ja) * | 2002-06-10 | 2008-02-06 | マイクロバイオ株式会社 | 試料検査装置 |
JP2004206069A (ja) * | 2002-10-31 | 2004-07-22 | Tokai Hit:Kk | 顕微鏡観察用加温装置 |
JP2004180675A (ja) * | 2002-11-19 | 2004-07-02 | Sanyo Electric Co Ltd | インキュベータ |
US20050051723A1 (en) * | 2003-07-23 | 2005-03-10 | Neagle Bradley D. | Examination systems for biological samples |
US7765868B2 (en) * | 2003-09-23 | 2010-08-03 | Evotec Technologies Gmbh | Climate chamber for microscopes |
US7799559B2 (en) * | 2003-10-24 | 2010-09-21 | Olympus Corporation | Culture microscope apparatus |
JP2005323509A (ja) * | 2004-05-12 | 2005-11-24 | Inoue Keisuke | 遺伝子発現計測用細胞培養観察装置 |
JP4873885B2 (ja) | 2004-05-26 | 2012-02-08 | オリンパス株式会社 | 培養顕微鏡、及び、培養顕微鏡を制御するコンピュータプログラム |
DE102005023855A1 (de) * | 2004-05-26 | 2006-01-26 | Olympus Corporation | Kulturmikroskop und Computerprogramm zur Steuerung des Kulturmikroskops |
FI116946B (fi) * | 2004-07-09 | 2006-04-13 | Chip Man Technologies Oy | Laitteisto solujen kuvaamiseksi |
JP4631339B2 (ja) | 2004-07-27 | 2011-02-16 | 株式会社ニコン | 環境制御装置、温度調節装置および環境制御型分析装置 |
JP4868203B2 (ja) * | 2004-10-27 | 2012-02-01 | オリンパス株式会社 | 培養標本観察装置 |
JP4658565B2 (ja) * | 2004-10-28 | 2011-03-23 | オリンパス株式会社 | 顕微鏡及び顕微鏡の加温方法 |
JP4810093B2 (ja) * | 2004-12-28 | 2011-11-09 | オリンパス株式会社 | 培養観察装置および標本トレー保温装置および蓋 |
WO2007004385A1 (ja) * | 2005-07-05 | 2007-01-11 | Nikon Corporation | 培養装置 |
EP2031051B1 (en) * | 2006-06-16 | 2021-05-19 | PHC Holdings Corporation | Culture monitoring system |
-
2007
- 2007-06-12 EP EP07745077.3A patent/EP2031051B1/en active Active
- 2007-06-12 US US12/304,857 patent/US8455241B2/en active Active
- 2007-06-12 KR KR1020087030513A patent/KR101378204B1/ko active IP Right Grant
- 2007-06-12 JP JP2008521206A patent/JP5841304B2/ja active Active
- 2007-06-12 WO PCT/JP2007/061790 patent/WO2007145198A1/ja active Application Filing
- 2007-06-12 CN CN2007800217986A patent/CN101466823B/zh not_active Expired - Fee Related
-
2014
- 2014-04-07 JP JP2014078528A patent/JP5943956B2/ja active Active
-
2016
- 2016-01-05 JP JP2016000357A patent/JP6059372B2/ja active Active
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105907634B (zh) * | 2010-01-20 | 2018-09-07 | Emd密理博公司 | 细胞图像捕捉和远程监控方法 |
CN102762713A (zh) * | 2010-01-20 | 2012-10-31 | Emd密理博公司 | 细胞图像捕捉和远程监控系统 |
CN102762713B (zh) * | 2010-01-20 | 2016-04-27 | Emd密理博公司 | 细胞图像捕捉和远程监控系统 |
CN105907634A (zh) * | 2010-01-20 | 2016-08-31 | Emd密理博公司 | 细胞图像捕捉和远程监控方法 |
CN102289066A (zh) * | 2011-08-12 | 2011-12-21 | 北京航空航天大学 | 一种多细胞培养过程自动显微成像系统 |
CN102827758A (zh) * | 2012-09-24 | 2012-12-19 | 长春理工大学 | 细胞工厂中细胞显微观察监测仪 |
CN104774906A (zh) * | 2015-04-24 | 2015-07-15 | 南京爱贝生物科技有限公司 | 一种活细胞连续观察方法 |
CN107034131A (zh) * | 2015-11-05 | 2017-08-11 | 奥林巴斯株式会社 | 观察装置以及观察方法 |
CN105586259A (zh) * | 2016-01-20 | 2016-05-18 | 中国科学院广州生物医药与健康研究院 | 细胞培养中细胞图像获取装置的控制系统及控制方法 |
CN107151627A (zh) * | 2016-03-03 | 2017-09-12 | 奥林巴斯株式会社 | 观察装置、测定系统、观察方法以及记录介质 |
CN107227258A (zh) * | 2016-03-23 | 2017-10-03 | 奥林巴斯株式会社 | 观察装置及其控制方法、测定系统、培养容器、记录介质 |
CN111486891A (zh) * | 2019-01-29 | 2020-08-04 | 株式会社岛津制作所 | 摄像环境测定器以及摄像环境测定系统 |
USD907244S1 (en) | 2019-06-14 | 2021-01-05 | Emd Millipore Corporation | Cell imager |
CN110452819A (zh) * | 2019-07-29 | 2019-11-15 | 西安医学院 | 一种可观测的低压低氧细胞培养箱 |
CN110747115A (zh) * | 2019-11-19 | 2020-02-04 | 长春理工大学 | 细胞工厂生物反应器显微光电监测系统 |
CN115948243A (zh) * | 2022-09-30 | 2023-04-11 | 河北医科大学第二医院 | 一种高内涵专用低氧工作站 |
Also Published As
Publication number | Publication date |
---|---|
JP5841304B2 (ja) | 2016-01-13 |
JP6059372B2 (ja) | 2017-01-11 |
CN101466823B (zh) | 2013-04-03 |
JP5943956B2 (ja) | 2016-07-05 |
JP2014128290A (ja) | 2014-07-10 |
EP2031051B1 (en) | 2021-05-19 |
EP2031051A1 (en) | 2009-03-04 |
EP2031051A4 (en) | 2014-01-08 |
KR20090020614A (ko) | 2009-02-26 |
KR101378204B1 (ko) | 2014-03-26 |
WO2007145198A1 (ja) | 2007-12-21 |
JPWO2007145198A1 (ja) | 2009-10-29 |
JP2016041086A (ja) | 2016-03-31 |
US8455241B2 (en) | 2013-06-04 |
US20090325280A1 (en) | 2009-12-31 |
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