CN101426790B - 1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途 - Google Patents

1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途 Download PDF

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Publication number
CN101426790B
CN101426790B CN200780014526.3A CN200780014526A CN101426790B CN 101426790 B CN101426790 B CN 101426790B CN 200780014526 A CN200780014526 A CN 200780014526A CN 101426790 B CN101426790 B CN 101426790B
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diaza
dicyclo
obstacle
disease
illness
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CN101426790A (zh
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D·彼特斯
G·M·奥尔森
E·O·尼尔森
D·B·逖米尔曼
S·C·劳彻尔
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Saniona AS
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Neurosearch AS
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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CN200780014526.3A 2006-05-30 2007-05-29 1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途 Expired - Fee Related CN101426790B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200600731 2006-05-30
DKPA200600731 2006-05-30
PCT/EP2007/055169 WO2007138038A1 (en) 2006-05-30 2007-05-29 Novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use

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CN101426790A CN101426790A (zh) 2009-05-06
CN101426790B true CN101426790B (zh) 2012-03-14

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CN200780014526.3A Expired - Fee Related CN101426790B (zh) 2006-05-30 2007-05-29 1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途
CNA200780015245XA Pending CN101432286A (zh) 2006-05-30 2007-05-29 新颖的1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途

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CNA200780015245XA Pending CN101432286A (zh) 2006-05-30 2007-05-29 新颖的1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物和它们的医药用途

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US (4) US7807667B2 (enExample)
EP (3) EP2194056B1 (enExample)
JP (2) JP2009538866A (enExample)
KR (1) KR101458194B1 (enExample)
CN (2) CN101426790B (enExample)
AT (3) ATE463497T1 (enExample)
AU (2) AU2007267174B2 (enExample)
BR (1) BRPI0708843A2 (enExample)
CA (2) CA2653818A1 (enExample)
DE (2) DE602007005802D1 (enExample)
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PT (1) PT2032575E (enExample)
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UA (1) UA95946C2 (enExample)
WO (2) WO2007138037A1 (enExample)
ZA (1) ZA200807756B (enExample)

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PT2032575E (pt) 2006-05-30 2010-07-09 Neurosearch As NOVO DERIVADO DE 1,4-DIAZA-BICICLO[3,2,2]NONIL-OXADIAZOLILO E A SUA APLICAÆO MéDICA
CA2667545A1 (en) * 2006-10-25 2008-05-02 Neurosearch A/S Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
US7935695B2 (en) 2007-08-17 2011-05-03 Neurosearch A/S 1,4-diaza-bicyclo[3.2.2]nonyl heteroaryl derivatives useful as nicotinic acetylcholine receptor ligands
RU2010135037A (ru) 2008-03-11 2012-04-20 Ньюросерч А/С (DK) Новые производные, 1,4-диазабицикло[3.2.2]нонилоксадиазолил, полезные в качестве модуляторов никотиновых ацетилхолиновых рецепторов
WO2009150138A1 (en) * 2008-06-10 2009-12-17 Neurosearch A/S Novel oxadiazolyl-diazabicyclononane derivatives and their medical use
WO2010043539A1 (en) * 2008-10-13 2010-04-22 Neurosearch A/S Novel oxadiazolyl-diazabicyclononane derivatives and their medical use
US20110257161A1 (en) * 2008-12-04 2011-10-20 Neurosearch A/S Novel diaza-bicyclononyl-phenyl derivatives and their medical use
CN102300574A (zh) 2009-01-26 2011-12-28 神经研究公司 新的吲哚基-*二唑基-二氮杂二环壬烷衍生物及它们的医药和诊断用途
WO2010086280A1 (en) 2009-01-27 2010-08-05 Neurosearch A/S Novel n-oxides of furanyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
WO2010086279A1 (en) 2009-01-27 2010-08-05 Neurosearch A/S Novel dibenzofuranyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
US20120238553A1 (en) * 2009-01-27 2012-09-20 Neurosearch A/S Novel benzodioxolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
WO2010130768A1 (en) * 2009-05-14 2010-11-18 Neurosearch A/S Novel 1,4-diaza-bicyclo[3.2.1]octane derivatives useful as nicotinic acetylcholine receptor modulators
JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
US20120288443A1 (en) 2009-11-11 2012-11-15 Neurosearch A/S Labelled pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their use in diagnostic methods
EP2513097A1 (en) 2009-12-18 2012-10-24 NeuroSearch AS Diazabicyclononyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators
WO2012139925A1 (en) 2011-04-15 2012-10-18 Neurosearch A/S Labelled and un-labelled methyl-pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
CN111499615B (zh) 2017-08-04 2024-02-02 斯基霍克疗法公司 用于调节剪接的方法和组合物
HUE066783T2 (hu) 2018-04-18 2024-09-28 Constellation Pharmaceuticals Inc Metil módosító enzimek modulátorai, ezek készítményei és alkalmazásuk
CA3100977A1 (en) 2018-05-21 2019-11-28 Constellation Pharmaceuticals, Inc. Modulators of methyl modifying enzymes, compositions and uses thereof
JP2022519294A (ja) * 2019-02-04 2022-03-22 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物
CN114007613A (zh) 2019-02-05 2022-02-01 斯基霍克疗法公司 用于调节剪接的方法和组合物
JP7603595B2 (ja) 2019-02-06 2024-12-20 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物

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