RU2427581C2 - Новые 1,4-диаза-бицикло[3.2.2]нонил-оксадиазолильные производные и их медицинское применение - Google Patents

Новые 1,4-диаза-бицикло[3.2.2]нонил-оксадиазолильные производные и их медицинское применение Download PDF

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RU2427581C2
RU2427581C2 RU2008139481/04A RU2008139481A RU2427581C2 RU 2427581 C2 RU2427581 C2 RU 2427581C2 RU 2008139481/04 A RU2008139481/04 A RU 2008139481/04A RU 2008139481 A RU2008139481 A RU 2008139481A RU 2427581 C2 RU2427581 C2 RU 2427581C2
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Russia
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bicyclo
diaza
nonyl
pharmaceutically acceptable
disorders
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RU2008139481/04A
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Russian (ru)
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RU2008139481A (ru
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Дан ПЕТЕРС (DK)
Дан ПЕТЕРС
Гуннар М. ОЛЬСЕН (DK)
Гуннар М. Ольсен
Эльсебет Эстергорд НЕЛЬСЕН (DK)
Эльсебет Эстергорд НЕЛЬСЕН
Даниэль Б. ТИММЕРМАНН (DK)
Даниэль Б. Тиммерманн
Стивен Чарльз ЛОХЕЛЬ (DK)
Стивен Чарльз ЛОХЕЛЬ
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НьюроСёрч А/С
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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  • Cardiology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Pregnancy & Childbirth (AREA)
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  • Pulmonology (AREA)
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RU2008139481/04A 2006-05-30 2007-05-29 Новые 1,4-диаза-бицикло[3.2.2]нонил-оксадиазолильные производные и их медицинское применение RU2427581C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200600731 2006-05-30
DKPA200600731 2006-05-30

Publications (2)

Publication Number Publication Date
RU2008139481A RU2008139481A (ru) 2010-07-10
RU2427581C2 true RU2427581C2 (ru) 2011-08-27

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RU2008139481/04A RU2427581C2 (ru) 2006-05-30 2007-05-29 Новые 1,4-диаза-бицикло[3.2.2]нонил-оксадиазолильные производные и их медицинское применение

Country Status (23)

Country Link
US (4) US8158619B2 (enExample)
EP (3) EP2194056B1 (enExample)
JP (2) JP2009538866A (enExample)
KR (1) KR101458194B1 (enExample)
CN (2) CN101432286A (enExample)
AT (3) ATE463497T1 (enExample)
AU (2) AU2007267174B2 (enExample)
BR (1) BRPI0708843A2 (enExample)
CA (2) CA2653769A1 (enExample)
DE (2) DE602007005802D1 (enExample)
DK (2) DK2032574T3 (enExample)
ES (1) ES2342334T3 (enExample)
IL (1) IL193925A (enExample)
MX (2) MX2008014886A (enExample)
MY (1) MY147764A (enExample)
NO (1) NO20085398L (enExample)
NZ (1) NZ571288A (enExample)
PL (1) PL2032575T3 (enExample)
PT (1) PT2032575E (enExample)
RU (1) RU2427581C2 (enExample)
UA (1) UA95946C2 (enExample)
WO (2) WO2007138038A1 (enExample)
ZA (1) ZA200807756B (enExample)

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EP2079734A1 (en) * 2006-10-25 2009-07-22 NeuroSearch A/S Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
WO2009024517A1 (en) 2007-08-17 2009-02-26 Neurosearch A/S Novel 1,4-diaza-bicyclo[3.2.2]nonyl heteroaryl derivatives useful as nicotinic acetylcholine receptor ligands
US8106042B2 (en) 2008-03-11 2012-01-31 Neurosearch A/S 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives useful as modulator of nicotinic acetylcholine receptors
US20110112078A1 (en) * 2008-06-10 2011-05-12 Neurosearch A/S Novel oxadiazolyl-diazabicyclononane derivatives and their medical use
US20110263577A1 (en) * 2008-10-13 2011-10-27 Neurosearch A/S Novel oxadiazolyl-diazabicyclononane derivatives and their medical use
US20110257161A1 (en) * 2008-12-04 2011-10-20 Neurosearch A/S Novel diaza-bicyclononyl-phenyl derivatives and their medical use
WO2010084185A1 (en) 2009-01-26 2010-07-29 Neurosearch A/S Novel indolyl-oxadiazolyl-diazabicyclononane derivatives and their medical and diagnostical use
US20120028968A1 (en) 2009-01-27 2012-02-02 Neurosearch A/S Novel dibenzofuranyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
WO2010086280A1 (en) 2009-01-27 2010-08-05 Neurosearch A/S Novel n-oxides of furanyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
US20120238553A1 (en) * 2009-01-27 2012-09-20 Neurosearch A/S Novel benzodioxolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
US20120071469A1 (en) * 2009-05-14 2012-03-22 Neurosearch A/S Novel 1,4-diaza-bicyclo[3.2.1]octane derivatives useful as nicotinic acetylcholine receptor modulators
TWI558398B (zh) 2009-09-22 2016-11-21 諾華公司 菸鹼乙醯膽鹼受體α７活化劑之用途
WO2011058002A1 (en) 2009-11-11 2011-05-19 Neurosearch A/S Labelled pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their use in diagnostic methods
WO2011073296A1 (en) 2009-12-18 2011-06-23 Neurosearch A/S Diazabicyclononyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators
WO2012139925A1 (en) 2011-04-15 2012-10-18 Neurosearch A/S Labelled and un-labelled methyl-pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use
MX2020001425A (es) 2017-08-04 2020-08-06 Skyhawk Therapeutics Inc Metodos y composiciones para modular el empalme.
MX2020010999A (es) 2018-04-18 2021-01-20 Constellation Pharmaceuticals Inc Moduladores de enzimas modificadoras de metilo, composiciones y usos de estos.
EP3797108B1 (en) 2018-05-21 2022-07-20 Constellation Pharmaceuticals, Inc. Modulators of methyl modifying enzymes, compositions and uses thereof
WO2020163248A1 (en) 2019-02-04 2020-08-13 Skyhawk Therapeutics, Inc. Methods and compositions for modulating splicing
CN113660936A (zh) * 2019-02-04 2021-11-16 斯基霍克疗法公司 用于调节剪接的方法和组合物
WO2020163541A1 (en) 2019-02-05 2020-08-13 Skyhawk Therapeutics, Inc. Methods and compositions for modulating splicing
KR102913697B1 (ko) 2019-02-05 2026-01-15 스카이호크 테라퓨틱스, 인코포레이티드 스플라이싱을 조절하는 방법 및 조성물
JP7603594B2 (ja) 2019-02-06 2024-12-20 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物
KR102925385B1 (ko) 2019-02-06 2026-02-11 스카이호크 테라퓨틱스, 인코포레이티드 스플라이싱을 조절하는 방법 및 조성물
PE20220562A1 (es) 2019-07-24 2022-04-13 Constellation Pharmaceuticals Inc Formas cristalinas de 7-cloro-2-(4-(3-metoxiazetidin-1-il)ciclohexil)-2,4-dimetil-n-((6-metil-4-(metiltio)-2-oxo-1,2-dihidropiridin-3-il)metil)benzo[d][1,3]dioxol-5-carboxamida

Citations (3)

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