CN101115746A - 用于制备苯并呋喃的新方法 - Google Patents

用于制备苯并呋喃的新方法 Download PDF

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Publication number
CN101115746A
CN101115746A CNA2006800039630A CN200680003963A CN101115746A CN 101115746 A CN101115746 A CN 101115746A CN A2006800039630 A CNA2006800039630 A CN A2006800039630A CN 200680003963 A CN200680003963 A CN 200680003963A CN 101115746 A CN101115746 A CN 101115746A
Authority
CN
China
Prior art keywords
formula
dimethyl
pyrimidine
chloro
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800039630A
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English (en)
Chinese (zh)
Inventor
彼得·施内德
彻奥拜·塔赫塔奥伊
马丁·布朗恩
索拉努·格赖弗勒丁格-波纳鲁
于尔根·约格
劳伦特·施米特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arpida AG
Original Assignee
Arpida AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arpida AG filed Critical Arpida AG
Publication of CN101115746A publication Critical patent/CN101115746A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
CNA2006800039630A 2005-02-18 2006-02-10 用于制备苯并呋喃的新方法 Pending CN101115746A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2005001695 2005-02-18
EP2005/001695 2005-02-18
PCT/EP2006/001179 WO2006087140A1 (en) 2005-02-18 2006-02-10 Novell processes for the preparation of a benzofuran

Publications (1)

Publication Number Publication Date
CN101115746A true CN101115746A (zh) 2008-01-30

Family

ID=36283919

Family Applications (4)

Application Number Title Priority Date Filing Date
CNA2006800039630A Pending CN101115746A (zh) 2005-02-18 2006-02-10 用于制备苯并呋喃的新方法
CN2011100324952A Pending CN102079727A (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的方法
CN2006800039626A Expired - Fee Related CN101115743B (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的新方法
CN2011100324933A Expired - Fee Related CN102140094B (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN2011100324952A Pending CN102079727A (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的方法
CN2006800039626A Expired - Fee Related CN101115743B (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的新方法
CN2011100324933A Expired - Fee Related CN102140094B (zh) 2005-02-18 2006-02-10 用于制备2h-色烯的方法

Country Status (22)

Country Link
US (2) US20080221324A1 (https=)
EP (3) EP1856109A1 (https=)
JP (2) JP2008530156A (https=)
KR (2) KR20070106635A (https=)
CN (4) CN101115746A (https=)
AU (2) AU2006215788B2 (https=)
BG (2) BG109938A (https=)
BR (2) BRPI0607797A2 (https=)
CA (2) CA2596668A1 (https=)
CZ (2) CZ2007536A3 (https=)
EE (2) EE200700050A (https=)
HU (2) HUP0700604A3 (https=)
IL (2) IL184405A0 (https=)
MX (2) MX2007009283A (https=)
NO (2) NO20073678L (https=)
NZ (1) NZ556800A (https=)
RO (2) RO122912B8 (https=)
RU (2) RU2397980C2 (https=)
TR (1) TR200705187T1 (https=)
TW (2) TW200640914A (https=)
WO (2) WO2006087143A1 (https=)
ZA (2) ZA200706422B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110372746A (zh) * 2019-07-11 2019-10-25 辽宁石油化工大学 一种合成β-胺基膦氧化合物的方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070106635A (ko) * 2005-02-18 2007-11-02 아르피다 아게 2ｈ-크로멘의 제조를 위한 신규한 방법들
CN102112108A (zh) * 2008-04-08 2011-06-29 阿西诺药品有限公司 水性医药剂型
US7947293B2 (en) 2008-04-08 2011-05-24 Arpida Ag Aqueous pharmaceutical formulation
FR2949465B1 (fr) * 2009-09-01 2011-08-12 Pf Medicament Derives chromones, leur procede de preparation et leurs applications therapeutiques
CN110606831A (zh) * 2018-06-14 2019-12-24 上海度德医药科技有限公司 一种Iclaprim的新中间体及其制备方法和应用
CN110818693B (zh) * 2018-08-07 2023-06-02 上海度德医药科技有限公司 一种艾拉普林甲磺酸盐晶型b及其制备方法
CN109988156B (zh) * 2019-03-12 2021-12-28 广东中科药物研究有限公司 一种氨基嘧啶化合物
CN110642792B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体的制备方法
CN110724135B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110724108B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110746361B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110713483B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林中间体及艾拉普林的制备方法
CN110790753B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林对甲苯磺酸盐、其制备方法和应用
CN110818694B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体及其应用
CN113493461A (zh) * 2020-04-01 2021-10-12 上海医药工业研究院 一种七元杂环化合物或其盐、其制备方法及应用
CN117700410B (zh) * 2023-05-20 2025-07-04 山东康诺生物工程有限公司 一种3-(2-氯乙基)-2-甲基-9-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2709634A1 (de) * 1977-03-05 1978-09-07 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
DE69618986T2 (de) * 1995-12-04 2002-06-20 Arpida Ag, Muenchenstein Diaminopyrimidine, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung als antibakterielle mittel
WO2002010156A1 (en) * 2000-07-29 2002-02-07 Arpida Ag Benzofuran derivatives and their use as antibacterial agents
US7365205B2 (en) * 2001-06-20 2008-04-29 Daiichi Sankyo Company, Limited Diamine derivatives
CN100443482C (zh) * 2003-07-11 2008-12-17 阿皮德公开股份有限公司 苯并呋喃衍生物及其在制备治疗由细菌引起的感染的药物中的用途
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
KR20070106635A (ko) * 2005-02-18 2007-11-02 아르피다 아게 2ｈ-크로멘의 제조를 위한 신규한 방법들

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110372746A (zh) * 2019-07-11 2019-10-25 辽宁石油化工大学 一种合成β-胺基膦氧化合物的方法

Also Published As

Publication number Publication date
JP2009505943A (ja) 2009-02-12
EP2270003A1 (en) 2011-01-05
IL184404A0 (en) 2007-10-31
EE200700050A (et) 2007-12-17
ZA200706422B (en) 2008-09-25
JP2008530156A (ja) 2008-08-07
BG109938A (bg) 2008-05-30
MX2007009282A (es) 2008-02-19
EE200700051A (et) 2007-12-17
TW200640914A (en) 2006-12-01
CN101115743A (zh) 2008-01-30
RO122853B1 (ro) 2010-03-30
KR20070106636A (ko) 2007-11-02
BG109937A (bg) 2008-05-30
HUP0700605A3 (en) 2008-02-28
RO122912B8 (ro) 2010-09-30
NZ556800A (en) 2011-01-28
CA2596669A1 (en) 2006-08-24
US20080161561A1 (en) 2008-07-03
HUP0700604A2 (en) 2008-01-28
US20080221324A1 (en) 2008-09-11
EP1856109A1 (en) 2007-11-21
WO2006087140A1 (en) 2006-08-24
MX2007009283A (es) 2008-02-19
CN101115743B (zh) 2011-04-13
EP1856106A1 (en) 2007-11-21
NO20073678L (no) 2007-09-03
RO122912B1 (ro) 2010-04-30
CN102140094B (zh) 2012-06-06
TR200705187T1 (tr) 2007-11-21
HUP0700605A2 (en) 2008-01-28
HUP0700604A3 (en) 2008-02-28
RU2397980C2 (ru) 2010-08-27
CZ2007537A3 (cs) 2008-02-20
RU2007134583A (ru) 2009-03-27
RU2007134584A (ru) 2009-03-27
CN102140094A (zh) 2011-08-03
KR20070106635A (ko) 2007-11-02
AU2006215788B2 (en) 2011-10-20
AU2006215788A1 (en) 2006-08-24
ZA200706421B (en) 2008-11-26
CN102079727A (zh) 2011-06-01
CA2596668A1 (en) 2006-08-24
CZ2007536A3 (cs) 2008-02-20
WO2006087143A8 (en) 2008-11-27
NO20073701L (no) 2007-09-03
IL184405A0 (en) 2007-10-31
TW200640912A (en) 2006-12-01
WO2006087143A1 (en) 2006-08-24
AU2006215785A1 (en) 2006-08-24
BRPI0607797A2 (pt) 2010-10-19
BRPI0607758A2 (pt) 2010-03-23

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