CN101023181A - 提高类异戊二烯化合物的产生的方法 - Google Patents

提高类异戊二烯化合物的产生的方法 Download PDF

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Publication number
CN101023181A
CN101023181A CNA2005800243430A CN200580024343A CN101023181A CN 101023181 A CN101023181 A CN 101023181A CN A2005800243430 A CNA2005800243430 A CN A2005800243430A CN 200580024343 A CN200580024343 A CN 200580024343A CN 101023181 A CN101023181 A CN 101023181A
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host cell
hmg
cell
genetically modified
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Chinese (zh)
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J·D·基斯林
J·D·纽曼
D·J·皮特拉
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University of California San Diego UCSD
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CNA2005800243430A 2004-05-21 2005-05-20 提高类异戊二烯化合物的产生的方法 Pending CN101023181A (zh)

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US57349204P 2004-05-21 2004-05-21
US60/573,492 2004-05-21

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CN101023181A true CN101023181A (zh) 2007-08-22

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US (2) US7183089B2 (enExample)
EP (2) EP2365090A1 (enExample)
JP (1) JP4926061B2 (enExample)
CN (1) CN101023181A (enExample)
AT (1) ATE537269T1 (enExample)
AU (1) AU2005327292B2 (enExample)
BR (1) BRPI0510115B1 (enExample)
CA (1) CA2567547C (enExample)
ES (1) ES2379368T3 (enExample)
MX (1) MXPA06013502A (enExample)
WO (1) WO2006085899A2 (enExample)

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CN103602626A (zh) * 2013-10-12 2014-02-26 中国科学院青岛生物能源与过程研究所 一种以油脂为原料生产甲羟戊酸的方法及其构建的基因工程菌
CN104039974A (zh) * 2011-11-09 2014-09-10 阿迈瑞斯公司 乙酰辅酶a衍生的类异戊二烯的生产
CN105112454A (zh) * 2008-05-16 2015-12-02 Reg生命科学有限责任公司 产生碳氢化合物的方法和组合物
CN106119112A (zh) * 2008-03-27 2016-11-16 基因组股份公司 用于产生己二酸和其他化合物的微生物
CN106367508A (zh) * 2016-09-13 2017-02-01 东北农业大学 一种用于鉴定杂合型类异戊二烯化合物产生菌的简并引物与应用
US9816124B2 (en) 2013-02-01 2017-11-14 Tianjin Institute Of Industrial Biotechnology, Chinese Academy Of Sciences Recombinant microorganism for preparing terpenoid and method for constructing recombinant microorganism
CN116925991A (zh) * 2023-07-28 2023-10-24 天津大学 高产甲羟戊酸的重组盐单胞菌菌株及构建方法与应用
WO2023227104A1 (zh) * 2022-05-26 2023-11-30 牛津大学(苏州)科技有限公司 一种用于合成萜烯的共培养系统和方法
WO2025108471A1 (zh) * 2023-11-24 2025-05-30 牛津大学(苏州)科技有限公司 用于合成目标化合物的共培养系统和方法

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JP5827601B2 (ja) * 2012-07-04 2015-12-02 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
CN105051195B (zh) 2013-02-06 2019-09-06 埃沃尔瓦公司 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法
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Cited By (16)

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CN106119112A (zh) * 2008-03-27 2016-11-16 基因组股份公司 用于产生己二酸和其他化合物的微生物
CN106119112B (zh) * 2008-03-27 2021-07-13 基因组股份公司 用于产生己二酸和其他化合物的微生物
US11186854B2 (en) 2008-05-16 2021-11-30 Genomatica, Inc. Methods and compositions for producing hydrocarbons
US10563231B2 (en) 2008-05-16 2020-02-18 Genomatica, Inc. Methods and compositions for producing hydrocarbons
CN105112455B (zh) * 2008-05-16 2016-08-17 Reg生命科学有限责任公司 产生碳氢化合物的方法和组合物
CN105112454A (zh) * 2008-05-16 2015-12-02 Reg生命科学有限责任公司 产生碳氢化合物的方法和组合物
CN105112454B (zh) * 2008-05-16 2017-01-18 Reg生命科学有限责任公司 产生碳氢化合物的方法和组合物
CN104039974B (zh) * 2011-11-09 2016-10-12 阿迈瑞斯公司 乙酰辅酶a衍生的类异戊二烯的生产
CN104039974A (zh) * 2011-11-09 2014-09-10 阿迈瑞斯公司 乙酰辅酶a衍生的类异戊二烯的生产
US9816124B2 (en) 2013-02-01 2017-11-14 Tianjin Institute Of Industrial Biotechnology, Chinese Academy Of Sciences Recombinant microorganism for preparing terpenoid and method for constructing recombinant microorganism
CN103602626B (zh) * 2013-10-12 2016-02-10 中国科学院青岛生物能源与过程研究所 一种以油脂为原料生产甲羟戊酸的方法及其构建的基因工程菌
CN103602626A (zh) * 2013-10-12 2014-02-26 中国科学院青岛生物能源与过程研究所 一种以油脂为原料生产甲羟戊酸的方法及其构建的基因工程菌
CN106367508A (zh) * 2016-09-13 2017-02-01 东北农业大学 一种用于鉴定杂合型类异戊二烯化合物产生菌的简并引物与应用
WO2023227104A1 (zh) * 2022-05-26 2023-11-30 牛津大学(苏州)科技有限公司 一种用于合成萜烯的共培养系统和方法
CN116925991A (zh) * 2023-07-28 2023-10-24 天津大学 高产甲羟戊酸的重组盐单胞菌菌株及构建方法与应用
WO2025108471A1 (zh) * 2023-11-24 2025-05-30 牛津大学(苏州)科技有限公司 用于合成目标化合物的共培养系统和方法

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Publication number Publication date
EP1765418A4 (en) 2008-07-02
CA2567547A1 (en) 2006-08-17
US7670825B2 (en) 2010-03-02
ES2379368T3 (es) 2012-04-25
US20060079476A1 (en) 2006-04-13
EP1765418A2 (en) 2007-03-28
BRPI0510115A (pt) 2007-09-25
MXPA06013502A (es) 2007-03-01
EP2365090A1 (en) 2011-09-14
WO2006085899A3 (en) 2007-05-18
BRPI0510115B1 (pt) 2022-09-27
ATE537269T1 (de) 2011-12-15
AU2005327292B2 (en) 2010-11-04
AU2005327292A1 (en) 2006-08-17
JP4926061B2 (ja) 2012-05-09
EP1765418B1 (en) 2011-12-14
US7183089B2 (en) 2007-02-27
WO2006085899A2 (en) 2006-08-17
US20090004724A1 (en) 2009-01-01
CA2567547C (en) 2012-10-23
JP2008500063A (ja) 2008-01-10

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