CN100580079C - 神经祖细胞群体 - Google Patents
神经祖细胞群体 Download PDFInfo
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- CN100580079C CN100580079C CN01809662A CN01809662A CN100580079C CN 100580079 C CN100580079 C CN 100580079C CN 01809662 A CN01809662 A CN 01809662A CN 01809662 A CN01809662 A CN 01809662A CN 100580079 C CN100580079 C CN 100580079C
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
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- Neurosurgery (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20560000P | 2000-05-17 | 2000-05-17 | |
| US60/205,600 | 2000-05-17 | ||
| US25760800P | 2000-12-22 | 2000-12-22 | |
| US60/257,608 | 2000-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1429267A CN1429267A (zh) | 2003-07-09 |
| CN100580079C true CN100580079C (zh) | 2010-01-13 |
Family
ID=26900583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN01809662A Expired - Fee Related CN100580079C (zh) | 2000-05-17 | 2001-05-16 | 神经祖细胞群体 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US20020009743A1 (OSRAM) |
| EP (1) | EP1287116A2 (OSRAM) |
| JP (5) | JP5943533B2 (OSRAM) |
| KR (1) | KR100903755B1 (OSRAM) |
| CN (1) | CN100580079C (OSRAM) |
| AU (2) | AU2001263199B2 (OSRAM) |
| CA (1) | CA2409698C (OSRAM) |
| GB (1) | GB2379447B (OSRAM) |
| IL (2) | IL152741A0 (OSRAM) |
| WO (1) | WO2001088104A2 (OSRAM) |
Families Citing this family (211)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7410798B2 (en) * | 2001-01-10 | 2008-08-12 | Geron Corporation | Culture system for rapid expansion of human embryonic stem cells |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| AU4752700A (en) | 1999-05-03 | 2000-11-17 | Karolinska Innovations Ab | Materials and methods relating to neuronal development |
| ATE319996T1 (de) * | 1999-12-16 | 2006-03-15 | Chugai Pharmaceutical Co Ltd | Verfahren zum auffinden eines heilmittels für krebs mit hilfe von interaktionsdomänen von p53 und mortalin |
| US20050042749A1 (en) * | 2001-05-16 | 2005-02-24 | Carpenter Melissa K. | Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease |
| WO2001068815A1 (en) | 2000-03-14 | 2001-09-20 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| US7011828B2 (en) * | 2000-03-14 | 2006-03-14 | Es Cell International Pte. Ltd. | Implanting neural progenitor cells derived for human embryonic stem cells |
| IL152741A0 (en) | 2000-05-17 | 2003-06-24 | Geron Corp | Neural progenitor cell populations |
| US7250294B2 (en) * | 2000-05-17 | 2007-07-31 | Geron Corporation | Screening small molecule drugs using neural cells differentiated from human embryonic stem cells |
| US6921665B2 (en) * | 2000-11-27 | 2005-07-26 | Roslin Institute (Edinburgh) | Selective antibody targeting of undifferentiated stem cells |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| JP3763749B2 (ja) * | 2001-03-28 | 2006-04-05 | 独立行政法人科学技術振興機構 | 脊髄におけるシナプス形成ニューロンを誘導する中枢神経系前駆細胞 |
| US7943376B2 (en) | 2001-04-27 | 2011-05-17 | Stem Cell Therapuetics Inc. | Platelet derived growth factor (PDGF)-derived neurospheres define a novel class of progenitor cells |
| CN101029302B (zh) * | 2001-06-21 | 2011-03-30 | 杰龙公司 | 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞 |
| JP3886346B2 (ja) * | 2001-06-22 | 2007-02-28 | サンバイオ,インコーポレイティド | 骨髄間質細胞由来Schwann細胞を含む神経再生用医薬組成物 |
| DE10134667A1 (de) * | 2001-07-20 | 2003-02-06 | Neuroprogen Gmbh Leipzig | Verfahren zur Herstellung isolierter Zellkulturen, Kulturmedium zur Kultivierung von Zellkulturen und Zellkultur |
| US6887706B2 (en) | 2001-10-03 | 2005-05-03 | Wisconsin Alumni Research Foundation | Method of in vitro differentiation of transplantable neural precursor cells from primate embryonic stem cells |
| US7588937B2 (en) | 2001-10-03 | 2009-09-15 | Wisconsin Alumni Research Foundation | Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells |
| US8153424B2 (en) | 2001-10-03 | 2012-04-10 | Wisconsin Alumni Research Foundation | Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells |
| US7129034B2 (en) * | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
| EP2292734A1 (en) | 2001-12-07 | 2011-03-09 | Geron Corporation | Hematopoietic cells from human embryonic stem cells |
| JP4374469B2 (ja) * | 2002-01-09 | 2009-12-02 | 独立行政法人科学技術振興機構 | 記憶障害治療剤 |
| AU2003202988A1 (en) | 2002-01-14 | 2003-07-30 | The Board Of Trustees Of The University Of Illinois | Use of modified pyrimidine compounds to promote stem cell migration and proliferation |
| CA2473749C (en) * | 2002-01-23 | 2012-05-22 | University Of Utah Research Foundation | Pure populations of astrocyte restricted precursor cells and methods for isolation and use thereof |
| AU2003228517B2 (en) * | 2002-04-16 | 2007-06-21 | Dana-Farber Cancer Institute, Inc. | Cancer models |
| AU2003229132B9 (en) * | 2002-06-05 | 2009-07-23 | Es Cell International Pte Ltd | Generation of neural stem cells from undifferentiated human embryonic stem cells |
| EP2360241A1 (en) * | 2002-06-05 | 2011-08-24 | ES Cell International Pte Ltd. | Stem cells |
| US7285415B2 (en) * | 2002-07-11 | 2007-10-23 | The Regents Of The University Of California | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US20050101014A1 (en) | 2002-07-11 | 2005-05-12 | Keirstead Hans S. | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US7632679B2 (en) * | 2002-07-16 | 2009-12-15 | The Trustees Of Columbia University In The City Of New York | Systems and methods for screening for modulators of neural differentiation |
| US20040224302A1 (en) * | 2002-07-16 | 2004-11-11 | Thomas Jessel | Systems and methods for screening for modulators of neural differentiation |
| AU2003269354B2 (en) * | 2002-09-24 | 2008-03-06 | Neuro Therapeutics Ab | Methods for promoting dopaminergic neuronal development by using NG4A-subfamily and Wnt-ligands |
| WO2004029203A2 (en) * | 2002-09-25 | 2004-04-08 | Bresagen, Inc. | Compositions and methods for enrichment of neural stem cells using ceramide analogs |
| US20040147020A1 (en) * | 2002-11-01 | 2004-07-29 | The Regents Of The University Of Colorado, A Body Corporate | Dopamine neurons from human embryonic stem cells |
| US20050265983A1 (en) * | 2002-11-17 | 2005-12-01 | Eldad Melamed | Methods, nucleic acid constructs and cells for treating neurodegenerative disorders |
| WO2004053071A2 (en) * | 2002-12-09 | 2004-06-24 | Judith Kelleher-Andersson | Method for discovering neurogenic agents |
| EP1572984B8 (en) | 2002-12-16 | 2016-06-01 | Technion Research & Development Foundation Ltd. | Feeder-free, xeno-free culture system for human embryonic stem cells |
| WO2004076624A2 (en) * | 2002-12-18 | 2004-09-10 | Bresagen, Inc. | Compositions and methods for neural cell production and stabilization |
| US8642332B2 (en) * | 2003-03-07 | 2014-02-04 | Cornell Research Foundation, Inc. | Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain |
| ZA200401646B (en) * | 2003-03-12 | 2004-06-07 | Reliance Life Sciences Pvt Ltd | Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells. |
| BRPI0408733A (pt) * | 2003-03-12 | 2006-03-07 | Reliance Life Sciences Pvt Ltd | derivação de neurÈnios dopaminérgicos terminalmente diferenciados de células tronco embriÈnicas humanas |
| US7153650B2 (en) | 2003-03-13 | 2006-12-26 | Geron Corporation | Marker system for preparing and characterizing high-quality human embryonic stem cells |
| US20060183221A1 (en) * | 2003-03-31 | 2006-08-17 | Schulz Thomas C | Method for neural differentiation of embryonic stem cells using protease passaging techniques |
| WO2004099395A2 (en) * | 2003-05-08 | 2004-11-18 | Cellartis Ab | A method for the generation of neural progenitor cells |
| WO2006040615A2 (en) * | 2003-06-11 | 2006-04-20 | Jan Remmereit | Differenciation of stem cells for therapeutic use |
| AU2004247961B2 (en) * | 2003-06-12 | 2010-06-24 | Yeda Research & Development Co.Ltd | Enhancement of oligodendrocyte differentiation |
| KR20060115351A (ko) * | 2003-08-29 | 2006-11-08 | 위스콘신 얼럼나이 리서어치 화운데이션 | 영장류 배아 줄기 세포 기원의 신경 줄기 세포, 운동 뉴런및 도파민 뉴런의 시험관내 분화 방법 |
| US7820439B2 (en) * | 2003-09-03 | 2010-10-26 | Reliance Life Sciences Pvt Ltd. | In vitro generation of GABAergic neurons from pluripotent stem cells |
| US20050148069A1 (en) * | 2003-09-24 | 2005-07-07 | Gage Fred H. | IGF-1 instructs multipotent adult CNS neural stem cells to an oligodendroglial lineage |
| US20070269412A1 (en) | 2003-12-02 | 2007-11-22 | Celavie Biosciences, Llc | Pluripotent cells |
| CA2551266C (en) | 2003-12-30 | 2011-07-26 | Seoul National University Industry Foundation | Embryonic stem cell line and method for preparing the same |
| US7829332B2 (en) * | 2004-02-13 | 2010-11-09 | Cornell Research Foundation, Inc. | Purines are self-renewal signals for neural stem cells, and purine receptor antagonists promote neuronal and glial differentiation therefrom |
| JP5226928B2 (ja) * | 2004-04-16 | 2013-07-03 | 株式会社カネカ | 細胞の分化転換方法 |
| US20050272149A1 (en) * | 2004-06-02 | 2005-12-08 | Life & Brain Gmbh | Therapeutic delivery of adenosine into a tissue |
| GB2414995B (en) | 2004-06-09 | 2006-11-15 | Univ Edinburgh | Neural stem cells |
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