CN100549004C - 螺环杂环衍生物及其应用方法 - Google Patents

螺环杂环衍生物及其应用方法 Download PDF

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CN100549004C
CN100549004C CNB2004800356909A CN200480035690A CN100549004C CN 100549004 C CN100549004 C CN 100549004C CN B2004800356909 A CNB2004800356909 A CN B2004800356909A CN 200480035690 A CN200480035690 A CN 200480035690A CN 100549004 C CN100549004 C CN 100549004C
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CN1922169A (zh
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罗兰·E·多勒
伯特兰·勒布尔多内克
克里斯多佛·W·耶洛
顾敏华
褚国华
保罗·安森·塔特希尔
拉拉·K·莱斯特
周勤
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Adolor Corp
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CNB2004800356909A 2003-10-01 2004-10-01 螺环杂环衍生物及其应用方法 Expired - Fee Related CN100549004C (zh)

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US7598261B2 (en) * 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7812183B2 (en) 2005-09-01 2010-10-12 Janssen Pharmaceutica Nv Benzopyran derivatives as potassium channel openers
ATE543813T1 (de) 2005-09-01 2012-02-15 Janssen Pharmaceutica Nv Neue benzopyranderivate als kaliumkanalöffner
US7576207B2 (en) * 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US20090186901A1 (en) * 2006-05-05 2009-07-23 Ulrich Reiser Chemical compounds
EP2063886A2 (en) * 2006-09-12 2009-06-03 Adolor Corporation Use of n-containing spirocompounds for the enhancement of cognitive function
TWI425945B (zh) * 2007-05-28 2014-02-11 Seldar Pharma Inc 四氫異喹啉-1-酮衍生物或其鹽
ES2370378T3 (es) * 2008-01-30 2011-12-14 Cephalon, Inc. Derivados sustituidos de piperidina espirocíclica como ligandos del receptor de histamina h3.
CA2712897A1 (en) * 2008-01-30 2009-08-06 Pharmacopeia, Inc. Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands
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TWI520964B (zh) 2011-02-02 2016-02-11 維泰克斯製藥公司 作為離子通道調節劑之吡咯并吡-螺環哌啶醯胺
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