JP4976134B2 - スピロ環複素環誘導体及びそれらを使用する方法 - Google Patents
スピロ環複素環誘導体及びそれらを使用する方法 Download PDFInfo
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- JP4976134B2 JP4976134B2 JP2006534173A JP2006534173A JP4976134B2 JP 4976134 B2 JP4976134 B2 JP 4976134B2 JP 2006534173 A JP2006534173 A JP 2006534173A JP 2006534173 A JP2006534173 A JP 2006534173A JP 4976134 B2 JP4976134 B2 JP 4976134B2
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- pain
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- 0 BC1(*2)C(*)(**=C)C(*)C(CI)*C11C2C(*)*C(*)C(*)*1 Chemical compound BC1(*2)C(*)(**=C)C(*)C(CI)*C11C2C(*)*C(*)C(*)*1 0.000 description 10
- LFVMYMNVAHNZBS-UHFFFAOYSA-N C(CN1C=COCC1)[n]1nnc(-c2cccc(C3=CC4(CCNCC4)Oc4ccccc34)c2)n1 Chemical compound C(CN1C=COCC1)[n]1nnc(-c2cccc(C3=CC4(CCNCC4)Oc4ccccc34)c2)n1 LFVMYMNVAHNZBS-UHFFFAOYSA-N 0.000 description 1
- HMMKISPSIWTSMJ-UHFFFAOYSA-N CC(C)(C)OC(N(CC1)CCC11Oc2ccccc2C(c2cccc(-c3n[nH]nn3)c2)=C1)=O Chemical compound CC(C)(C)OC(N(CC1)CCC11Oc2ccccc2C(c2cccc(-c3n[nH]nn3)c2)=C1)=O HMMKISPSIWTSMJ-UHFFFAOYSA-N 0.000 description 1
- DUXYIRXTKRMWLS-UHFFFAOYSA-N CCN(CC)C(c(cc1)ccc1C1=CC2(CCNCC2)Oc(cc2)c1cc2NS(C)(=O)=O)=O Chemical compound CCN(CC)C(c(cc1)ccc1C1=CC2(CCNCC2)Oc(cc2)c1cc2NS(C)(=O)=O)=O DUXYIRXTKRMWLS-UHFFFAOYSA-N 0.000 description 1
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Addiction (AREA)
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- Immunology (AREA)
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- Anesthesiology (AREA)
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- Oncology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50786403P | 2003-10-01 | 2003-10-01 | |
| US60/507,864 | 2003-10-01 | ||
| PCT/US2004/032479 WO2005033073A2 (en) | 2003-10-01 | 2004-10-01 | Spirocyclic heterocyclic derivatives and methods of their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011107724A Division JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007507532A JP2007507532A (ja) | 2007-03-29 |
| JP2007507532A5 JP2007507532A5 (enExample) | 2007-11-22 |
| JP4976134B2 true JP4976134B2 (ja) | 2012-07-18 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534173A Expired - Fee Related JP4976134B2 (ja) | 2003-10-01 | 2004-10-01 | スピロ環複素環誘導体及びそれらを使用する方法 |
| JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US7338962B2 (enExample) |
| EP (1) | EP1675847B1 (enExample) |
| JP (2) | JP4976134B2 (enExample) |
| KR (2) | KR20140015122A (enExample) |
| CN (2) | CN101921279A (enExample) |
| AU (1) | AU2004278414B2 (enExample) |
| BR (1) | BRPI0415165A (enExample) |
| CA (1) | CA2541014A1 (enExample) |
| CO (1) | CO5690640A2 (enExample) |
| IL (2) | IL174702A (enExample) |
| NZ (3) | NZ593444A (enExample) |
| WO (1) | WO2005033073A2 (enExample) |
| ZA (1) | ZA200603414B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011201896A (ja) * | 2003-10-01 | 2011-10-13 | Adolor Corp | スピロ環複素環誘導体及びそれらを使用する方法 |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0100860A3 (en) * | 1997-12-11 | 2003-03-28 | Janssen Pharmaceutica Nv | Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them |
| US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| ES2379098T3 (es) | 2005-09-01 | 2012-04-20 | Janssen Pharmaceutica Nv | Derivados de benzopirano novedosos como abridores del canal de potasio |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011201896A (ja) * | 2003-10-01 | 2011-10-13 | Adolor Corp | スピロ環複素環誘導体及びそれらを使用する方法 |
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