JP2007507532A5 - - Google Patents
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- Publication number
- JP2007507532A5 JP2007507532A5 JP2006534173A JP2006534173A JP2007507532A5 JP 2007507532 A5 JP2007507532 A5 JP 2007507532A5 JP 2006534173 A JP2006534173 A JP 2006534173A JP 2006534173 A JP2006534173 A JP 2006534173A JP 2007507532 A5 JP2007507532 A5 JP 2007507532A5
- Authority
- JP
- Japan
- Prior art keywords
- international
- opioid receptor
- documents cited
- peptidic
- pamphlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101100244562 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) oprD gene Proteins 0.000 description 2
- 108700023159 delta Opioid Receptors Proteins 0.000 description 2
- 102000048124 delta Opioid Receptors Human genes 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50786403P | 2003-10-01 | 2003-10-01 | |
| US60/507,864 | 2003-10-01 | ||
| PCT/US2004/032479 WO2005033073A2 (en) | 2003-10-01 | 2004-10-01 | Spirocyclic heterocyclic derivatives and methods of their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011107724A Division JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007507532A JP2007507532A (ja) | 2007-03-29 |
| JP2007507532A5 true JP2007507532A5 (enExample) | 2007-11-22 |
| JP4976134B2 JP4976134B2 (ja) | 2012-07-18 |
Family
ID=34421676
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534173A Expired - Fee Related JP4976134B2 (ja) | 2003-10-01 | 2004-10-01 | スピロ環複素環誘導体及びそれらを使用する方法 |
| JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US7338962B2 (enExample) |
| EP (1) | EP1675847B1 (enExample) |
| JP (2) | JP4976134B2 (enExample) |
| KR (2) | KR20140015122A (enExample) |
| CN (2) | CN101921279A (enExample) |
| AU (1) | AU2004278414B2 (enExample) |
| BR (1) | BRPI0415165A (enExample) |
| CA (1) | CA2541014A1 (enExample) |
| CO (1) | CO5690640A2 (enExample) |
| IL (2) | IL174702A (enExample) |
| NZ (3) | NZ593444A (enExample) |
| WO (1) | WO2005033073A2 (enExample) |
| ZA (1) | ZA200603414B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0100860A3 (en) * | 1997-12-11 | 2003-03-28 | Janssen Pharmaceutica Nv | Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them |
| BRPI0415165A (pt) * | 2003-10-01 | 2007-01-09 | Adolor Corp | composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem |
| US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| ES2379098T3 (es) | 2005-09-01 | 2012-04-20 | Janssen Pharmaceutica Nv | Derivados de benzopirano novedosos como abridores del canal de potasio |
| CA2620846A1 (en) | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| CA2648831A1 (en) * | 2006-05-05 | 2007-11-15 | Ulrich Reiser | Spiro- (tho) benzopyran-2, 4' -piperidine-and cyclohexane derivatives as inhibitors of specific cell cycle enzymes |
| AU2007294968A1 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
| TWI425945B (zh) * | 2007-05-28 | 2014-02-11 | Seldar Pharma Inc | 四氫異喹啉-1-酮衍生物或其鹽 |
| ES2390004T3 (es) * | 2008-01-30 | 2012-11-05 | Cephalon, Inc. | Derivados sustituidos de piperidina espirocíclica como ligandos del receptor de la histamina 3(H3) |
| JP5524082B2 (ja) * | 2008-01-30 | 2014-06-18 | セファロン、インク. | ヒスタミン−3(h3)受容体リガンドとしての置換スピロ環状ピペリジン誘導体 |
| US20110263545A1 (en) | 2008-05-20 | 2011-10-27 | Naweed Muhammad | Hepatoprotectant acetaminophen mutual prodrugs |
| TW201604196A (zh) | 2011-02-02 | 2016-02-01 | 維泰克斯製藥公司 | 作為離子通道調節劑之吡咯并吡-螺環哌啶醯胺 |
| US10385070B2 (en) | 2011-02-18 | 2019-08-20 | Vertex Pharmaceuticals Incorporated | Chroman-spirocyclic piperidine amides as modulators of ion channels |
| EP2686325B1 (en) | 2011-03-14 | 2016-12-14 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
| US8835488B2 (en) * | 2011-03-23 | 2014-09-16 | Trevena, Inc. | Opioid receptor ligands and methods of using and making same |
| WO2014028800A1 (en) | 2012-08-16 | 2014-02-20 | Janssen Pharmaceutica Nv | Substituted pyrazoles as n-type calcium channel blockers |
| CN110054694B (zh) | 2012-08-21 | 2024-02-20 | 詹森药业有限公司 | 阿立哌唑半抗原的抗体及其用途 |
| PL2888592T3 (pl) | 2012-08-21 | 2018-03-30 | Janssen Pharmaceutica Nv | Przeciwciała względem kwetiapiny i ich zastosowania |
| CA2882489A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone haptens and use thereof |
| WO2014031662A2 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to olanzapine and use thereof |
| CN104736564B (zh) | 2012-08-21 | 2019-02-05 | 詹森药业有限公司 | 喹硫平半抗原的抗体及其用途 |
| PT3321254T (pt) | 2012-08-21 | 2020-10-20 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol e seu uso em imunoensaios |
| CA2882595C (en) | 2012-08-21 | 2019-06-04 | Ortho-Clinical Diagnostics, Inc. | Antibodies to olanzapine haptens and use thereof |
| PT2888593T (pt) | 2012-08-21 | 2018-12-12 | Janssen Pharmaceutica Nv | Anticorpos contra risperidona e utilizações dos mesmos |
| PT2888284T (pt) | 2012-08-21 | 2022-11-18 | Janssen Pharmaceutica Nv | Anticorpos dirigidos contra haptenos de risperidona e a sua utilização |
| JP6270845B2 (ja) | 2012-08-21 | 2018-01-31 | ヤンセン ファーマシューティカ エヌ.ベー. | アリピプラゾールに対する抗体及びその使用 |
| EP2888277A4 (en) | 2012-08-21 | 2016-05-18 | Ortho Clinical Diagnostics Inc | ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF |
| TW201434837A (zh) | 2012-12-14 | 2014-09-16 | Purdue Pharma Lp | 螺環嗎啡喃及其用途 |
| TW201441199A (zh) | 2012-12-28 | 2014-11-01 | Purdue Pharma Lp | 經取代之嗎啡喃類及其用途 |
| US9453002B2 (en) | 2013-08-16 | 2016-09-27 | Janssen Pharmaceutica Nv | Substituted imidazoles as N-type calcium channel blockers |
| WO2015023289A1 (en) * | 2013-08-16 | 2015-02-19 | Janssen Pharmaceutica Nv | Substituted imidazoles as n-type calcium channel blockers |
| US9299409B2 (en) * | 2013-09-11 | 2016-03-29 | Tadashi Miyakawa | Semiconductor storage device |
| US9340542B2 (en) | 2013-12-26 | 2016-05-17 | Purdue Pharma L.P. | Propellane-based compounds and the use thereof |
| WO2016100823A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| US10633336B2 (en) | 2014-12-19 | 2020-04-28 | The Broad Institute, Inc. | Dopamine D2 receptor ligands |
| KR20170025848A (ko) | 2015-08-31 | 2017-03-08 | 한국건설생활환경시험연구원 | 교류 직결형 엘이디 램프 결합 구조 |
| US10588889B2 (en) | 2015-12-14 | 2020-03-17 | Trevena, Inc. | Methods of treating hyperalgesia |
| JP6994461B2 (ja) | 2015-12-17 | 2022-02-04 | ヤンセン ファーマシューティカ エヌ.ベー. | クエチアピンに対する抗体及びその使用 |
| WO2017106501A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
| TW202321258A (zh) * | 2021-08-02 | 2023-06-01 | 大陸商上海樞境生物科技有限公司 | 氧雜螺環類衍生物、製備方法及其用途 |
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| DE3837809A1 (de) * | 1988-11-08 | 1990-05-10 | Merck Patent Gmbh | Tetralinderivate |
| DE68921972T2 (de) | 1988-12-13 | 1995-11-16 | Beecham Group Plc | Benzopyran und verwandte Verbindungen. |
| DE69015886T2 (de) * | 1989-06-05 | 1995-08-03 | Tokuyama Corp | Fotochromische Verbindung, deren Zusammensetzung und Verwendung. |
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| SE0101769D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101768D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101773D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
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| SE0203302D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
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| BRPI0415165A (pt) | 2003-10-01 | 2007-01-09 | Adolor Corp | composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem |
| US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| AU2007294968A1 (en) * | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
-
2004
- 2004-10-01 BR BRPI0415165-8A patent/BRPI0415165A/pt not_active IP Right Cessation
- 2004-10-01 CN CN2009101634060A patent/CN101921279A/zh active Pending
- 2004-10-01 CA CA002541014A patent/CA2541014A1/en not_active Abandoned
- 2004-10-01 US US10/957,554 patent/US7338962B2/en not_active Expired - Fee Related
- 2004-10-01 AU AU2004278414A patent/AU2004278414B2/en not_active Ceased
- 2004-10-01 NZ NZ593444A patent/NZ593444A/xx not_active IP Right Cessation
- 2004-10-01 KR KR1020127001970A patent/KR20140015122A/ko not_active Abandoned
- 2004-10-01 WO PCT/US2004/032479 patent/WO2005033073A2/en not_active Ceased
- 2004-10-01 CN CNB2004800356909A patent/CN100549004C/zh not_active Expired - Fee Related
- 2004-10-01 EP EP04817130A patent/EP1675847B1/en not_active Expired - Lifetime
- 2004-10-01 KR KR1020067008451A patent/KR101255074B1/ko not_active Expired - Fee Related
- 2004-10-01 JP JP2006534173A patent/JP4976134B2/ja not_active Expired - Fee Related
- 2004-10-01 NZ NZ546834A patent/NZ546834A/en not_active IP Right Cessation
-
2006
- 2006-03-30 IL IL174702A patent/IL174702A/en not_active IP Right Cessation
- 2006-04-21 CO CO06037980A patent/CO5690640A2/es not_active Application Discontinuation
- 2006-04-28 ZA ZA200603414A patent/ZA200603414B/en unknown
-
2007
- 2007-12-20 US US11/960,845 patent/US7638527B2/en not_active Expired - Fee Related
-
2009
- 2009-06-12 US US12/483,781 patent/US7906646B2/en not_active Expired - Fee Related
-
2010
- 2010-02-19 NZ NZ583451A patent/NZ583451A/en not_active IP Right Cessation
- 2010-03-05 US US12/718,439 patent/US8071611B2/en not_active Expired - Fee Related
- 2010-05-26 US US12/787,906 patent/US20100280058A1/en not_active Abandoned
- 2010-09-19 IL IL208249A patent/IL208249A/en not_active IP Right Cessation
-
2011
- 2011-05-13 JP JP2011107724A patent/JP2011201896A/ja active Pending
- 2011-10-17 US US13/274,616 patent/US20120165356A1/en not_active Abandoned
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