CN100475207C - 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 - Google Patents

治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 Download PDF

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Publication number
CN100475207C
CN100475207C CNB038117053A CN03811705A CN100475207C CN 100475207 C CN100475207 C CN 100475207C CN B038117053 A CNB038117053 A CN B038117053A CN 03811705 A CN03811705 A CN 03811705A CN 100475207 C CN100475207 C CN 100475207C
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China
Prior art keywords
phenyl
chloro
quinoline
imidazo
imidazol
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Expired - Fee Related
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CNB038117053A
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Chinese (zh)
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CN1655788A (zh
Inventor
C·加西亚-埃切夫-埃里亚
H-G·卡普拉罗
P·菲雷
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Novartis AG
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Novartis AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNB038117053A 2002-05-21 2003-05-20 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 Expired - Fee Related CN100475207C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0211649.9 2002-05-21
GBGB0211649.9A GB0211649D0 (en) 2002-05-21 2002-05-21 Organic compounds

Publications (2)

Publication Number Publication Date
CN1655788A CN1655788A (zh) 2005-08-17
CN100475207C true CN100475207C (zh) 2009-04-08

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CNB038117053A Expired - Fee Related CN100475207C (zh) 2002-05-21 2003-05-20 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物

Country Status (15)

Country Link
US (1) US7998972B2 (https=)
EP (1) EP1509521B8 (https=)
JP (1) JP4707389B2 (https=)
CN (1) CN100475207C (https=)
AT (1) ATE405564T1 (https=)
AU (1) AU2003240680A1 (https=)
BR (1) BR0311221A (https=)
CA (1) CA2485012A1 (https=)
DE (1) DE60323090D1 (https=)
DK (1) DK1509521T3 (https=)
ES (1) ES2312783T3 (https=)
GB (1) GB0211649D0 (https=)
PT (1) PT1509521E (https=)
SI (1) SI1509521T1 (https=)
WO (1) WO2003097641A2 (https=)

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