CN100462387C - DL-丙交酯-ε-己内酯共聚物 - Google Patents

DL-丙交酯-ε-己内酯共聚物 Download PDF

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Publication number
CN100462387C
CN100462387C CNB038075504A CN03807550A CN100462387C CN 100462387 C CN100462387 C CN 100462387C CN B038075504 A CNB038075504 A CN B038075504A CN 03807550 A CN03807550 A CN 03807550A CN 100462387 C CN100462387 C CN 100462387C
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CN
China
Prior art keywords
lactide
polymeric material
material according
caprolactone
copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB038075504A
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English (en)
Chinese (zh)
Other versions
CN1701083A (zh
Inventor
凯瑟琳娜·埃弗蒂娜·希斯英克
西奥多勒斯·阿德里亚努斯·科尔内留斯·弗里普森
汉斯·维歇尔·奎杰珀尔
罗布·斯滕达姆
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Polymeric Organ Ip Ltd By Share Ltd
Original Assignee
Polyganics BV
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Publication of CN1701083A publication Critical patent/CN1701083A/zh
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Prostheses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
CNB038075504A 2002-02-06 2003-02-05 DL-丙交酯-ε-己内酯共聚物 Expired - Fee Related CN100462387C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02075481A EP1334990A1 (en) 2002-02-06 2002-02-06 DL-Lactide-epsilon-caprolactone copolymers
EP02075481.8 2002-02-06
US10/308,214 2002-12-02

Publications (2)

Publication Number Publication Date
CN1701083A CN1701083A (zh) 2005-11-23
CN100462387C true CN100462387C (zh) 2009-02-18

Family

ID=27589147

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038075504A Expired - Fee Related CN100462387C (zh) 2002-02-06 2003-02-05 DL-丙交酯-ε-己内酯共聚物

Country Status (10)

Country Link
US (2) US7785628B2 (enExample)
EP (2) EP1334990A1 (enExample)
JP (1) JP4452507B2 (enExample)
CN (1) CN100462387C (enExample)
AT (1) ATE372355T1 (enExample)
AU (1) AU2003207416B2 (enExample)
CA (1) CA2475266C (enExample)
DE (1) DE60316115T3 (enExample)
ES (1) ES2292936T5 (enExample)
WO (1) WO2003066705A1 (enExample)

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US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
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EP1862186A4 (en) * 2005-03-23 2010-12-01 Jms Co Ltd STICK FOIL
US20070106035A1 (en) * 2005-10-26 2007-05-10 Medivas, Llc Aromatic di-acid-containing poly (ester amide) polymers and methods of use
CA2667944A1 (en) * 2005-10-26 2007-05-03 Medivas, Llc Aromatic di-acid-containing poly (ester amide) polymers and methods of use
CN101492532B (zh) * 2006-01-27 2012-05-16 浙江海正生物材料股份有限公司 苯甲酸亚锡作为催化剂的用途
BRPI0713060A2 (pt) 2006-06-28 2012-04-10 Gunze Kk polìmero biodegradável/absorvìvel tendo teor reduzido de catalisador de metal e processo para a produção do mesmo
US9089627B2 (en) * 2006-07-11 2015-07-28 Abbott Cardiovascular Systems Inc. Stent fabricated from polymer composite toughened by a dispersed phase
EP3009477B1 (en) 2006-07-20 2024-01-24 Orbusneich Medical Pte. Ltd Bioabsorbable polymeric composition for a medical device
EP2073754A4 (en) 2006-10-20 2012-09-26 Orbusneich Medical Inc BIOABSORBABLE POLYMER COMPOSITION AND MEDICAL DEVICE BACKGROUND
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
US20090181068A1 (en) 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
DE102008012620A1 (de) 2008-02-28 2009-09-03 Deutsche Institute Für Textil- Und Faserforschung Denkendorf Resorbierbares Blockpolymer, Verfahren zu seiner Herstellung und Verwendung
GB2463861B (en) * 2008-09-10 2012-09-26 Univ Manchester Medical device
US8758374B2 (en) 2010-09-15 2014-06-24 University Of Utah Research Foundation Method for connecting nerves via a side-to-side epineurial window using artificial conduits
US10842494B2 (en) 2011-10-17 2020-11-24 University Of Utah Research Foundation Methods and devices for connecting nerves
US9931121B2 (en) 2011-10-17 2018-04-03 University Of Utah Research Foundation Methods and devices for connecting nerves
CN102389589B (zh) * 2011-11-22 2014-06-11 何伟 一种生物降解型眼内植入膜片
GB2490269B (en) * 2012-07-12 2013-04-10 Univ Manchester Peripheral nerve growth scaffold including poly-E-caprolactone
US8968387B2 (en) 2012-07-23 2015-03-03 Abbott Cardiovascular Systems Inc. Shape memory bioresorbable polymer peripheral scaffolds
SG10201702047XA (en) * 2012-09-30 2017-04-27 Univ Singapore Bio-absorbable medicament-eluting ventilation tube
CN102911347A (zh) * 2012-10-22 2013-02-06 长沙理工大学 高分子量聚(L-丙交酯-co-己内酯)无规共聚物的制备方法
EP2985302B1 (en) 2013-04-12 2018-01-10 National University Corporation Kyoto Institute of Technology Method for producing lactide-lactone copolymer
US9815935B2 (en) 2013-04-15 2017-11-14 Kent State University Biodegradable side chain liquid crystal elastomers: smart responsive scaffolds (SRS) for tissue regeneration
CN104558557B (zh) * 2014-04-30 2017-02-15 中国科学院化学研究所 一种高粘度的3d打印聚酯和聚碳酸酯及其制备方法
CN107427605B (zh) * 2015-03-06 2021-06-04 聚合物器官Ip股份有限公司 神经帽及其制备
US10086109B2 (en) * 2015-06-02 2018-10-02 Ethicon, Inc. Absorbable medical devices based on novel films and foams made from semi-crystalline, segmented copolymers of lactide and epsilon-caprolactone exhibiting long term absorption characteristics
MX378264B (es) 2015-08-03 2025-03-10 Tolmar International Ltd Sistema para la entrega de polímeros líquidos para la administración prolongada de fármacos.
NL2016524B1 (en) 2016-03-31 2017-10-17 Polyganics Ip B V Tissue-adhesive material
EP3678768B1 (en) * 2017-09-04 2021-07-14 Nouryon Chemicals International B.V. Thermally expandable microspheres prepared from bio-based monomers
EP3461857A1 (en) * 2017-09-28 2019-04-03 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Surface-functionalised polymeric object and method of its production
WO2019166087A1 (en) 2018-02-28 2019-09-06 Fundación Tekniker Implantable nerve guidance conduit for nerve repair
CN113874442B (zh) * 2019-05-30 2023-06-16 东丽株式会社 聚合物组合物、成型体及神经再生诱导管
JP7456104B2 (ja) * 2019-09-05 2024-03-27 株式会社ジェイ・エム・エス 医療用補綴材
ES2966371T3 (es) * 2019-09-30 2024-04-22 Tolmar International Ltd Composiciones poliméricas líquidas y sistemas para el aporte prolongado de péptidos como ingredientes farmacéuticos activos
CN112521734B (zh) * 2020-10-14 2023-03-31 浙江中在医疗科技有限公司 一种可降解医用弹性体材料及其用途
CN112694730B (zh) * 2021-01-07 2022-05-10 江南大学 一种基于超支化聚合物制备高性能高流动性聚乳酸的方法
CN112831032B (zh) * 2021-01-07 2022-03-25 江南大学 一种高熔体流动性聚乳酸复合材料及其制备方法

Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2000135282A (ja) * 1998-10-30 2000-05-16 Gunze Ltd 手術用縫合糸

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US4057537A (en) * 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
US4539981A (en) * 1982-11-08 1985-09-10 Johnson & Johnson Products, Inc. Absorbable bone fixation device
NL9001984A (nl) * 1990-09-10 1992-04-01 Stamicarbon Werkwijze voor het produceren van een voorwerp van een copolymeer van lactide en epsilon-caprolacton voor medische toepassingen.
US5399666A (en) * 1994-04-21 1995-03-21 E. I. Du Pont De Nemours And Company Easily degradable star-block copolymers
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Non-Patent Citations (1)

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Also Published As

Publication number Publication date
ES2292936T5 (es) 2014-01-03
EP1472301B1 (en) 2007-09-05
US20100312340A1 (en) 2010-12-09
US8309137B2 (en) 2012-11-13
ES2292936T3 (es) 2008-03-16
CA2475266C (en) 2011-11-01
ATE372355T1 (de) 2007-09-15
EP1472301B2 (en) 2013-09-04
WO2003066705A1 (en) 2003-08-14
US7785628B2 (en) 2010-08-31
US20030147934A1 (en) 2003-08-07
JP2005517062A (ja) 2005-06-09
JP4452507B2 (ja) 2010-04-21
DE60316115T3 (de) 2014-01-16
DE60316115T2 (de) 2008-06-05
EP1472301A1 (en) 2004-11-03
CA2475266A1 (en) 2003-08-14
AU2003207416A1 (en) 2003-09-02
AU2003207416B2 (en) 2007-07-19
DE60316115D1 (de) 2007-10-18
EP1334990A1 (en) 2003-08-13
CN1701083A (zh) 2005-11-23

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C06 Publication
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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: POLYMER ORGAN IP CO., LTD.

Free format text: FORMER OWNER: POLYGANICS B. V.

Effective date: 20140801

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20140801

Address after: Groningen

Patentee after: Polymeric organ IP Limited by Share Ltd

Address before: Groningen

Patentee before: Polyganics B. V.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20090218

Termination date: 20210205