GB2490269B - Peripheral nerve growth scaffold including poly-E-caprolactone - Google Patents

Peripheral nerve growth scaffold including poly-E-caprolactone

Info

Publication number
GB2490269B
GB2490269B GB201212442A GB201212442A GB2490269B GB 2490269 B GB2490269 B GB 2490269B GB 201212442 A GB201212442 A GB 201212442A GB 201212442 A GB201212442 A GB 201212442A GB 2490269 B GB2490269 B GB 2490269B
Authority
GB
United Kingdom
Prior art keywords
caprolactone
nerve growth
peripheral nerve
including poly
scaffold including
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB201212442A
Other versions
GB201212442D0 (en
GB2490269A (en
Inventor
Sandra Downes
Giorgio Terenghi
Mingzhu Sun
Paul Kingham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manchester
Original Assignee
University of Manchester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Manchester filed Critical University of Manchester
Priority to GB201212442A priority Critical patent/GB2490269B/en
Publication of GB201212442D0 publication Critical patent/GB201212442D0/en
Publication of GB2490269A publication Critical patent/GB2490269A/en
Application granted granted Critical
Publication of GB2490269B publication Critical patent/GB2490269B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
GB201212442A 2012-07-12 2012-07-12 Peripheral nerve growth scaffold including poly-E-caprolactone Active GB2490269B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB201212442A GB2490269B (en) 2012-07-12 2012-07-12 Peripheral nerve growth scaffold including poly-E-caprolactone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201212442A GB2490269B (en) 2012-07-12 2012-07-12 Peripheral nerve growth scaffold including poly-E-caprolactone

Publications (3)

Publication Number Publication Date
GB201212442D0 GB201212442D0 (en) 2012-08-29
GB2490269A GB2490269A (en) 2012-10-24
GB2490269B true GB2490269B (en) 2013-04-10

Family

ID=46799539

Family Applications (1)

Application Number Title Priority Date Filing Date
GB201212442A Active GB2490269B (en) 2012-07-12 2012-07-12 Peripheral nerve growth scaffold including poly-E-caprolactone

Country Status (1)

Country Link
GB (1) GB2490269B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2463861B (en) 2008-09-10 2012-09-26 Univ Manchester Medical device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081552A1 (en) * 2000-04-19 2001-11-01 Iowa State University Research Foundation, Inc. Patterned substrates and methods for nerve regeneration
WO2003066705A1 (en) * 2002-02-06 2003-08-14 Polyganics B.V. Dl-lactide-ε-caprolactone copolymers
GB2386841A (en) * 2002-03-11 2003-10-01 Ind Tech Res Inst Multi-channel bioresorbable nerve regeneration conduit and process for preparing the same
WO2005046457A2 (en) * 2003-11-05 2005-05-26 Texas Scottish Rite Hospital For Children A biomimetic biosynthetic nerve implant
US20060002978A1 (en) * 2004-06-10 2006-01-05 Shea Lonnie D Biodegradable scaffolds and uses thereof
WO2006044904A2 (en) * 2004-10-15 2006-04-27 Vanderbilt University Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
WO2007021590A2 (en) * 2005-08-12 2007-02-22 Brown University Topographical templating of polymeric materials using cellular morphology

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081552A1 (en) * 2000-04-19 2001-11-01 Iowa State University Research Foundation, Inc. Patterned substrates and methods for nerve regeneration
WO2003066705A1 (en) * 2002-02-06 2003-08-14 Polyganics B.V. Dl-lactide-ε-caprolactone copolymers
GB2386841A (en) * 2002-03-11 2003-10-01 Ind Tech Res Inst Multi-channel bioresorbable nerve regeneration conduit and process for preparing the same
WO2005046457A2 (en) * 2003-11-05 2005-05-26 Texas Scottish Rite Hospital For Children A biomimetic biosynthetic nerve implant
US20060002978A1 (en) * 2004-06-10 2006-01-05 Shea Lonnie D Biodegradable scaffolds and uses thereof
WO2006044904A2 (en) * 2004-10-15 2006-04-27 Vanderbilt University Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
WO2007021590A2 (en) * 2005-08-12 2007-02-22 Brown University Topographical templating of polymeric materials using cellular morphology

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J Biomed Mater Res; Vol 31, pp 105-115 (1996). den Dunnen et al. "Light-microscopic and electron-microscopic evaluation of short-term nerve regeneration using a biodegradable poly(DL-lactide-E-caprolacton)nerve guide" *

Also Published As

Publication number Publication date
GB201212442D0 (en) 2012-08-29
GB2490269A (en) 2012-10-24

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