CN100347193C - 用于重构表面活性剂制备的改良的合成脂质混合物 - Google Patents

用于重构表面活性剂制备的改良的合成脂质混合物 Download PDF

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Publication number
CN100347193C
CN100347193C CNB038112531A CN03811253A CN100347193C CN 100347193 C CN100347193 C CN 100347193C CN B038112531 A CNB038112531 A CN B038112531A CN 03811253 A CN03811253 A CN 03811253A CN 100347193 C CN100347193 C CN 100347193C
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CN
China
Prior art keywords
dppc
reconstituted surfactant
surfactant according
popg
artificial peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CNB038112531A
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English (en)
Chinese (zh)
Other versions
CN1653088A (zh
Inventor
T·库斯泰德特
J·约翰松
B·罗伯特松
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Chiesi Farmaceutici SpA
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Chiesi Farmaceutici SpA
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Publication of CN1653088A publication Critical patent/CN1653088A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB038112531A 2002-05-17 2003-05-12 用于重构表面活性剂制备的改良的合成脂质混合物 Expired - Lifetime CN100347193C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI02A001058 2002-05-17
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito

Publications (2)

Publication Number Publication Date
CN1653088A CN1653088A (zh) 2005-08-10
CN100347193C true CN100347193C (zh) 2007-11-07

Family

ID=11449919

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038112531A Expired - Lifetime CN100347193C (zh) 2002-05-17 2003-05-12 用于重构表面活性剂制备的改良的合成脂质混合物

Country Status (26)

Country Link
US (2) US7511011B2 (https=)
EP (1) EP1506234B1 (https=)
JP (1) JP4883906B2 (https=)
KR (1) KR101028927B1 (https=)
CN (1) CN100347193C (https=)
AT (1) ATE353919T1 (https=)
AU (1) AU2003233320B2 (https=)
CA (1) CA2486152C (https=)
CY (1) CY1106667T1 (https=)
DE (1) DE60311798T2 (https=)
DK (1) DK1506234T3 (https=)
EA (1) EA007928B1 (https=)
ES (1) ES2282627T3 (https=)
HR (1) HRP20041058B1 (https=)
IL (2) IL165239A0 (https=)
IT (1) ITMI20021058A1 (https=)
MA (1) MA27960A1 (https=)
MX (1) MXPA04011369A (https=)
NZ (1) NZ536606A (https=)
PL (1) PL209649B1 (https=)
PT (1) PT1506234E (https=)
SI (1) SI1506234T1 (https=)
TN (1) TNSN04219A1 (https=)
UA (1) UA79609C2 (https=)
WO (1) WO2003097695A1 (https=)
ZA (1) ZA200409215B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CN102146053A (zh) 2003-03-24 2011-08-10 阿克西金药品公司 治疗哮喘及其它炎症或免疫性疾病的具有ccr3拮抗活性的2-苯氧基-和2-苯基磺酰胺衍生物
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
UA76074C2 (en) * 2005-11-09 2006-06-15 O V Palladin Inst Of Biochemis Calmophil, pharmaceutical composition for substitution therapy aimed at recovering malfunctioned surfactant system of lungs
GEP20125531B (en) * 2006-10-13 2012-05-25 Chiesi Farma Spa Reconstituted surfactants having improved properties
US8367643B2 (en) * 2007-03-29 2013-02-05 National Jewish Health Surfactant lipids, compositions thereof and uses thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
WO2009123119A1 (ja) 2008-04-02 2009-10-08 国立大学法人徳島大学 合成ペプチドを含有する抗原薬物ビークルとこれを用いる粘膜ワクチン
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
MX2013002145A (es) * 2010-08-30 2013-04-03 Hoffmann La Roche Tetranectina-apolipoproteina a-i, particulas lipidicas que la contienen y utilizacion de la misma.
BR112013033562A2 (pt) 2011-08-25 2017-02-14 Hoffmann La Roche proteína de fusão de tetranectina-apolipoproteína a-i encurtada, uma partícula de lipídio que a contém e uso das mesmas
AR093569A1 (es) 2012-11-21 2015-06-10 Chiesi Farm Spa Tensioactivos pulmonares reconstituidos

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047623A1 (en) * 1999-02-12 2000-08-17 Chiesi Farmaceutici S.P.A. Artificial peptides having surface activity and the use thereof in the preparation of artificial surfactant
WO2001076617A2 (en) * 2000-03-15 2001-10-18 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001164A1 (en) * 1993-06-30 1995-01-12 Genentech, Inc. Method for preparing liposomes
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
JP2003530356A (ja) * 2000-04-12 2003-10-14 アルタナ ファルマ アクチエンゲゼルシャフト 急性肺疾患の予防又は早期治療のための肺表面活性物質の新規使用
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047623A1 (en) * 1999-02-12 2000-08-17 Chiesi Farmaceutici S.P.A. Artificial peptides having surface activity and the use thereof in the preparation of artificial surfactant
WO2001076617A2 (en) * 2000-03-15 2001-10-18 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Effect of pulmonary surfactant protein B(SP-B) and calcium onphospholipid adsorption and squeeze-out ofphosphatidylglycerol form binary phospholipid monolayercontaining dipalmitoylphosphatidylcholine. YU S H et al.Biochimica et Biophysica Acta.,Vol.1126 No.1. 1992 *

Also Published As

Publication number Publication date
ZA200409215B (en) 2006-02-22
KR101028927B1 (ko) 2011-04-12
UA79609C2 (en) 2007-07-10
PL209649B1 (pl) 2011-09-30
AU2003233320A2 (en) 2003-12-02
ITMI20021058A1 (it) 2003-11-17
HK1079221A1 (zh) 2006-03-31
PL372751A1 (en) 2005-08-08
MXPA04011369A (es) 2005-02-17
WO2003097695A1 (en) 2003-11-27
TNSN04219A1 (en) 2007-03-12
AU2003233320B2 (en) 2008-06-19
DE60311798D1 (de) 2007-03-29
EP1506234B1 (en) 2007-02-14
EA007928B1 (ru) 2007-02-27
US20080242589A1 (en) 2008-10-02
AU2003233320A1 (en) 2003-12-02
NZ536606A (en) 2006-10-27
SI1506234T1 (sl) 2007-06-30
ATE353919T1 (de) 2007-03-15
KR20050016408A (ko) 2005-02-21
PT1506234E (pt) 2007-05-31
HRP20041058B1 (hr) 2013-11-22
CY1106667T1 (el) 2012-05-23
ITMI20021058A0 (it) 2002-05-17
DK1506234T3 (da) 2007-06-11
EP1506234A1 (en) 2005-02-16
EA200401385A1 (ru) 2005-08-25
DE60311798T2 (de) 2007-10-31
CA2486152C (en) 2012-09-11
CN1653088A (zh) 2005-08-10
US7511011B2 (en) 2009-03-31
IL165239A0 (en) 2005-12-18
CA2486152A1 (en) 2003-11-27
HRP20041058A2 (en) 2005-02-28
ES2282627T3 (es) 2007-10-16
JP2006504635A (ja) 2006-02-09
US20050176625A1 (en) 2005-08-11
MA27960A1 (fr) 2006-07-03
US7842664B2 (en) 2010-11-30
JP4883906B2 (ja) 2012-02-22
IL165239A (en) 2012-10-31

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