CY1106667T1 - Βελτιωμενα συνθετικα μιγματα λιπιδιων για την παρασκευη μιας ανασυγκροτημενης επιφανειοδραστικης ουσιας - Google Patents

Βελτιωμενα συνθετικα μιγματα λιπιδιων για την παρασκευη μιας ανασυγκροτημενης επιφανειοδραστικης ουσιας

Info

Publication number
CY1106667T1
CY1106667T1 CY20071100558T CY071100558T CY1106667T1 CY 1106667 T1 CY1106667 T1 CY 1106667T1 CY 20071100558 T CY20071100558 T CY 20071100558T CY 071100558 T CY071100558 T CY 071100558T CY 1106667 T1 CY1106667 T1 CY 1106667T1
Authority
CY
Cyprus
Prior art keywords
preparation
synthetic lipid
lipid mixtures
improved synthetic
surfactant
Prior art date
Application number
CY20071100558T
Other languages
English (en)
Inventor
Tore Curstedt
Jan Johansson
Bengt Robertson
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of CY1106667T1 publication Critical patent/CY1106667T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Η ευρεσιτεχνία αφορά ανασυγκροτημένες επιφανειοδραστικές ουσίες, οι οποίες αποτελούνται από τεχνητά φωσφολιπίδια και πεπτίδια ικανά να μειώσουν την τάση αέρα-υγρής επιφάνειας, και ιδιαίτερα ανασυγκροτημένες επιφανειοδραστικές ουσίες, οι οποίες περιλαμβάνουν ειδικά μίγματα φωσφολιπίδιων και τεχνητά πεπτίδια, τα οποία είναι ανάλογα της φυσικής επιφανειοδραστικής SP-C πρωτεΐνης, για την αντιμετώπιση του συνδρόμου αναπνευστικής δυσχέρειας (RDS) και άλλων ασθενειών, οι οποίες σχετίζονται με τις πνευμονικές επιφανειοδραστικές δυσλειτουργίες.
CY20071100558T 2002-05-17 2007-04-26 Βελτιωμενα συνθετικα μιγματα λιπιδιων για την παρασκευη μιας ανασυγκροτημενης επιφανειοδραστικης ουσιας CY1106667T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
PCT/EP2003/004937 WO2003097695A1 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant

Publications (1)

Publication Number Publication Date
CY1106667T1 true CY1106667T1 (el) 2012-05-23

Family

ID=11449919

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100558T CY1106667T1 (el) 2002-05-17 2007-04-26 Βελτιωμενα συνθετικα μιγματα λιπιδιων για την παρασκευη μιας ανασυγκροτημενης επιφανειοδραστικης ουσιας

Country Status (27)

Country Link
US (2) US7511011B2 (el)
EP (1) EP1506234B1 (el)
JP (1) JP4883906B2 (el)
KR (1) KR101028927B1 (el)
CN (1) CN100347193C (el)
AT (1) ATE353919T1 (el)
AU (1) AU2003233320B2 (el)
CA (1) CA2486152C (el)
CY (1) CY1106667T1 (el)
DE (1) DE60311798T2 (el)
DK (1) DK1506234T3 (el)
EA (1) EA007928B1 (el)
ES (1) ES2282627T3 (el)
HK (1) HK1079221A1 (el)
HR (1) HRP20041058B1 (el)
IL (2) IL165239A0 (el)
IT (1) ITMI20021058A1 (el)
MA (1) MA27960A1 (el)
MX (1) MXPA04011369A (el)
NZ (1) NZ536606A (el)
PL (1) PL209649B1 (el)
PT (1) PT1506234E (el)
SI (1) SI1506234T1 (el)
TN (1) TNSN04219A1 (el)
UA (1) UA79609C2 (el)
WO (1) WO2003097695A1 (el)
ZA (1) ZA200409215B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CN1802159B (zh) 2003-03-24 2013-04-24 阿克西金药品公司 治疗哮喘及其它炎症或免疫性疾病的具有ccr3拮抗活性的2-苯氧基-和2-苯基磺酰胺衍生物
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
UA76074C2 (en) * 2005-11-09 2006-06-15 O V Palladin Inst Of Biochemis Calmophil, pharmaceutical composition for substitution therapy aimed at recovering malfunctioned surfactant system of lungs
JP5405307B2 (ja) 2006-10-13 2014-02-05 キエージ・フアルマチエウテイチ・エツセ・ピ・ア 改善された性質を有する再構成サーファクタント
WO2008121811A2 (en) 2007-03-29 2008-10-09 National Jewish Medical And Research Center Surfactant lipids, compositions thereof, and uses thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
US8287887B2 (en) 2008-04-02 2012-10-16 The University Of Tokushima Antigen-and-drug vehicle comprising synthetic peptide, and mucosal vaccine using the same
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
RU2013112562A (ru) * 2010-08-30 2014-10-10 Ф. Хоффманн-Ля Рош Аг Тетранектин-аполипопротеин а-i, содержащие его липидные частицы и его применение
KR20140054115A (ko) 2011-08-25 2014-05-08 에프. 호프만-라 로슈 아게 단축 테트라넥틴-아포지단백질 a-i 융합 단백질, 그를 함유하는 지질 입자 및 그의 용도
KR102122088B1 (ko) 2012-11-21 2020-06-12 키에시 파르마슈티시 엣스. 피. 에이. 재구성된 폐 계면활성제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08512056A (ja) * 1993-06-30 1996-12-17 ジェネンテク・インコーポレイテッド リポソームの製造法
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
IT1308180B1 (it) 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
AU2001245848A1 (en) * 2000-03-15 2001-10-23 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection
JP2003530356A (ja) 2000-04-12 2003-10-14 アルタナ ファルマ アクチエンゲゼルシャフト 急性肺疾患の予防又は早期治療のための肺表面活性物質の新規使用
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
EP1506234A1 (en) 2005-02-16
PL372751A1 (en) 2005-08-08
HK1079221A1 (en) 2006-03-31
WO2003097695A1 (en) 2003-11-27
PT1506234E (pt) 2007-05-31
US7842664B2 (en) 2010-11-30
ITMI20021058A0 (it) 2002-05-17
TNSN04219A1 (en) 2007-03-12
NZ536606A (en) 2006-10-27
EA007928B1 (ru) 2007-02-27
DK1506234T3 (da) 2007-06-11
JP4883906B2 (ja) 2012-02-22
KR101028927B1 (ko) 2011-04-12
AU2003233320A2 (en) 2003-12-02
CN100347193C (zh) 2007-11-07
AU2003233320B2 (en) 2008-06-19
US20050176625A1 (en) 2005-08-11
ITMI20021058A1 (it) 2003-11-17
ES2282627T3 (es) 2007-10-16
DE60311798T2 (de) 2007-10-31
IL165239A (en) 2012-10-31
HRP20041058B1 (hr) 2013-11-22
JP2006504635A (ja) 2006-02-09
ZA200409215B (en) 2006-02-22
KR20050016408A (ko) 2005-02-21
AU2003233320A1 (en) 2003-12-02
US20080242589A1 (en) 2008-10-02
EA200401385A1 (ru) 2005-08-25
UA79609C2 (en) 2007-07-10
CN1653088A (zh) 2005-08-10
CA2486152A1 (en) 2003-11-27
PL209649B1 (pl) 2011-09-30
CA2486152C (en) 2012-09-11
HRP20041058A2 (en) 2005-02-28
IL165239A0 (en) 2005-12-18
MA27960A1 (fr) 2006-07-03
DE60311798D1 (de) 2007-03-29
MXPA04011369A (es) 2005-02-17
EP1506234B1 (en) 2007-02-14
ATE353919T1 (de) 2007-03-15
SI1506234T1 (sl) 2007-06-30
US7511011B2 (en) 2009-03-31

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