EA200401385A1 - Улучшенные синтетические липидные смеси для препарата синтетического сурфактанта - Google Patents

Улучшенные синтетические липидные смеси для препарата синтетического сурфактанта

Info

Publication number
EA200401385A1
EA200401385A1 EA200401385A EA200401385A EA200401385A1 EA 200401385 A1 EA200401385 A1 EA 200401385A1 EA 200401385 A EA200401385 A EA 200401385A EA 200401385 A EA200401385 A EA 200401385A EA 200401385 A1 EA200401385 A1 EA 200401385A1
Authority
EA
Eurasian Patent Office
Prior art keywords
synthetic
lipid mixtures
surfactant preparation
improved
synthetic surfactants
Prior art date
Application number
EA200401385A
Other languages
English (en)
Other versions
EA007928B1 (ru
Inventor
Торе Курстедт
Ян Йоханссон
Бенгт Робертсон
Original Assignee
КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. filed Critical КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Publication of EA200401385A1 publication Critical patent/EA200401385A1/ru
Publication of EA007928B1 publication Critical patent/EA007928B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Изобретение относится к синтетическим сурфактантам, состоящим из искусственных фосфолипидов и пептидов, способным снижать поверхностное натяжение на границе воздух-жидкость, более конкретно к синтетическим сурфактантам, содержащим особые фосфолипидные смеси и искусственные пептиды, которые являются аналогами природного белка SP-C сурфактанта, для лечения респираторного дистресс-синдрома (RDS) и других заболеваний, связанных с нарушениями функции легочного сурфактанта.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401385A 2002-05-17 2003-05-12 Улучшенные синтетические липидные смеси для препарата синтетического сурфактанта EA007928B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002MI001058A ITMI20021058A1 (it) 2002-05-17 2002-05-17 Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
PCT/EP2003/004937 WO2003097695A1 (en) 2002-05-17 2003-05-12 Improved synthetic lipid mixtures for the preparation of a reconstituted surfactant

Publications (2)

Publication Number Publication Date
EA200401385A1 true EA200401385A1 (ru) 2005-08-25
EA007928B1 EA007928B1 (ru) 2007-02-27

Family

ID=11449919

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401385A EA007928B1 (ru) 2002-05-17 2003-05-12 Улучшенные синтетические липидные смеси для препарата синтетического сурфактанта

Country Status (27)

Country Link
US (2) US7511011B2 (ru)
EP (1) EP1506234B1 (ru)
JP (1) JP4883906B2 (ru)
KR (1) KR101028927B1 (ru)
CN (1) CN100347193C (ru)
AT (1) ATE353919T1 (ru)
AU (1) AU2003233320B2 (ru)
CA (1) CA2486152C (ru)
CY (1) CY1106667T1 (ru)
DE (1) DE60311798T2 (ru)
DK (1) DK1506234T3 (ru)
EA (1) EA007928B1 (ru)
ES (1) ES2282627T3 (ru)
HK (1) HK1079221A1 (ru)
HR (1) HRP20041058B1 (ru)
IL (2) IL165239A0 (ru)
IT (1) ITMI20021058A1 (ru)
MA (1) MA27960A1 (ru)
MX (1) MXPA04011369A (ru)
NZ (1) NZ536606A (ru)
PL (1) PL209649B1 (ru)
PT (1) PT1506234E (ru)
SI (1) SI1506234T1 (ru)
TN (1) TNSN04219A1 (ru)
UA (1) UA79609C2 (ru)
WO (1) WO2003097695A1 (ru)
ZA (1) ZA200409215B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
BRPI0408682A (pt) 2003-03-24 2006-03-28 Actimis Pharmaceuticals Inc derivado de benzenossulfonamida, medicamento, uso do derivado de benzenossulfonamida, e, processo para controlar uma doença ou distúrbio inflamatórios ou imuno-reguladores em humanos e animais
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
UA76074C2 (en) * 2005-11-09 2006-06-15 O V Palladin Inst Of Biochemis Calmophil, pharmaceutical composition for substitution therapy aimed at recovering malfunctioned surfactant system of lungs
DK2078038T3 (da) * 2006-10-13 2013-12-02 Chiesi Farma Spa Rekonstituerede surfaktanter med forbedrede egenskaber
US8367643B2 (en) 2007-03-29 2013-02-05 National Jewish Health Surfactant lipids, compositions thereof and uses thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
CN101980721B (zh) 2008-04-02 2013-03-13 国立大学法人德岛大学 含有合成肽的抗原药物赋形剂和使用其的粘膜疫苗
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
AR082644A1 (es) * 2010-08-30 2012-12-19 Hoffmann La Roche Tetranectina-apolipoproteina a-i, particulas lipidicas que la contiene y utilizacion de la misma relacionado con el metabolismo de los lipidos y las enfermedades cardiovasculares
RU2014108240A (ru) 2011-08-25 2015-09-27 Ф. Хоффманн-Ля Рош Аг Укороченный тетранектин-аполипопротеин а-i гибридный белок, содержащая его липидная частица и их применения
ES2644317T3 (es) 2012-11-21 2017-11-28 Chiesi Farmaceutici S.P.A. Tensioactivos pulmonares reconstituidos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08512056A (ja) * 1993-06-30 1996-12-17 ジェネンテク・インコーポレイテッド リポソームの製造法
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
AU2001245848A1 (en) * 2000-03-15 2001-10-23 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection
US20030158087A1 (en) 2000-04-12 2003-08-21 Dietrich Hafner Novel use of fulmonary surfactant for the prophylaxis or early treatment if acute fulmonary diseases
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
EP1506234B1 (en) 2007-02-14
JP4883906B2 (ja) 2012-02-22
SI1506234T1 (sl) 2007-06-30
MA27960A1 (fr) 2006-07-03
IL165239A0 (en) 2005-12-18
EA007928B1 (ru) 2007-02-27
CA2486152C (en) 2012-09-11
EP1506234A1 (en) 2005-02-16
IL165239A (en) 2012-10-31
ES2282627T3 (es) 2007-10-16
TNSN04219A1 (en) 2007-03-12
JP2006504635A (ja) 2006-02-09
AU2003233320B2 (en) 2008-06-19
US7511011B2 (en) 2009-03-31
DE60311798D1 (de) 2007-03-29
AU2003233320A2 (en) 2003-12-02
WO2003097695A1 (en) 2003-11-27
PL209649B1 (pl) 2011-09-30
US20050176625A1 (en) 2005-08-11
ATE353919T1 (de) 2007-03-15
PT1506234E (pt) 2007-05-31
DE60311798T2 (de) 2007-10-31
CN1653088A (zh) 2005-08-10
KR20050016408A (ko) 2005-02-21
US20080242589A1 (en) 2008-10-02
MXPA04011369A (es) 2005-02-17
US7842664B2 (en) 2010-11-30
DK1506234T3 (da) 2007-06-11
KR101028927B1 (ko) 2011-04-12
AU2003233320A1 (en) 2003-12-02
UA79609C2 (en) 2007-07-10
CY1106667T1 (el) 2012-05-23
NZ536606A (en) 2006-10-27
ITMI20021058A1 (it) 2003-11-17
HRP20041058B1 (hr) 2013-11-22
HRP20041058A2 (en) 2005-02-28
CA2486152A1 (en) 2003-11-27
PL372751A1 (en) 2005-08-08
ITMI20021058A0 (it) 2002-05-17
ZA200409215B (en) 2006-02-22
CN100347193C (zh) 2007-11-07
HK1079221A1 (en) 2006-03-31

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