EA201000161A1 - Синтетические поверхностно-активные пептиды легких - Google Patents

Синтетические поверхностно-активные пептиды легких

Info

Publication number
EA201000161A1
EA201000161A1 EA201000161A EA201000161A EA201000161A1 EA 201000161 A1 EA201000161 A1 EA 201000161A1 EA 201000161 A EA201000161 A EA 201000161A EA 201000161 A EA201000161 A EA 201000161A EA 201000161 A1 EA201000161 A1 EA 201000161A1
Authority
EA
Eurasian Patent Office
Prior art keywords
peptides
synthetic surface
active lung
lung
active
Prior art date
Application number
EA201000161A
Other languages
English (en)
Other versions
EA023499B1 (ru
Inventor
Ян Йоханссон
Торе Карстедт
Бенгт Робертсон
Маурицио Дельканале
Original Assignee
КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. filed Critical КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.
Publication of EA201000161A1 publication Critical patent/EA201000161A1/ru
Publication of EA023499B1 publication Critical patent/EA023499B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Настоящее изобретение относится к аналогам пептидов природного поверхностно-активного белка SP-B и его применению в получении композиций для лечения или профилактики респираторного дистресс-синдрома (RDS) и других респираторных расстройств.
EA201000161A 2007-08-09 2008-07-17 Синтетические аналоги природного легочного сурфактантного белка sp-b и их применение EA023499B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07114083A EP2022798A1 (en) 2007-08-09 2007-08-09 Synthetic pulmonary surfactant peptides
PCT/EP2008/005842 WO2009018908A1 (en) 2007-08-09 2008-07-17 Synthetic pulmonary surfactant peptides

Publications (2)

Publication Number Publication Date
EA201000161A1 true EA201000161A1 (ru) 2010-08-30
EA023499B1 EA023499B1 (ru) 2016-06-30

Family

ID=39207936

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000161A EA023499B1 (ru) 2007-08-09 2008-07-17 Синтетические аналоги природного легочного сурфактантного белка sp-b и их применение

Country Status (14)

Country Link
US (1) US8148492B2 (ru)
EP (2) EP2022798A1 (ru)
JP (1) JP5441904B2 (ru)
KR (1) KR101516451B1 (ru)
CN (2) CN101827861A (ru)
AT (1) ATE503768T1 (ru)
AU (1) AU2008286026B2 (ru)
BR (1) BRPI0813619B1 (ru)
CA (1) CA2695805C (ru)
DE (1) DE602008005901D1 (ru)
EA (1) EA023499B1 (ru)
ES (1) ES2360976T3 (ru)
MX (1) MX2010001543A (ru)
WO (1) WO2009018908A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
DK2078038T3 (da) 2006-10-13 2013-12-02 Chiesi Farma Spa Rekonstituerede surfaktanter med forbedrede egenskaber
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2812018B1 (en) 2012-02-09 2018-12-05 University Of Rochester Novel sp-b&sp-c peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
AR093569A1 (es) 2012-11-21 2015-06-10 Chiesi Farm Spa Tensioactivos pulmonares reconstituidos
CN114437233A (zh) * 2020-11-06 2022-05-06 湖北健翔生物制药有限公司 一种多肽二聚体的定向合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2189825T3 (es) * 1993-12-08 2003-07-16 Mitsubishi Pharma Corp Nuevo peptido sintetico, tensioactivo pulmonar que lo contiene y remedio para el sindrome de malestar respiratorio.
DE4434629C1 (de) * 1994-09-28 1996-06-27 Byk Gulden Lomberg Chem Fab Zusammensetzungen zur Behandlung von IRDS und ARDS
DE19602332A1 (de) * 1996-01-24 1997-07-31 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung von pulverförmigen Lungensurfactant-Zubereitungen
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
KR20020081330A (ko) * 2000-02-16 2002-10-26 노오쓰웨스턴 유니버시티 폴리펩토이드 폐 계면활성제
FI20002177A0 (fi) 2000-10-02 2000-10-02 Orion Yhtymae Oyj Uusi yhdistelmä astman hoitoon
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
CA2658478C (en) * 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties

Also Published As

Publication number Publication date
WO2009018908A1 (en) 2009-02-12
JP2010535721A (ja) 2010-11-25
MX2010001543A (es) 2010-03-15
EP2022798A1 (en) 2009-02-11
EP2185588A1 (en) 2010-05-19
ES2360976T3 (es) 2011-06-10
EP2185588B1 (en) 2011-03-30
ATE503768T1 (de) 2011-04-15
CA2695805C (en) 2016-11-22
CA2695805A1 (en) 2009-02-12
CN108676088A (zh) 2018-10-19
US20090075892A1 (en) 2009-03-19
BRPI0813619B1 (pt) 2021-06-22
EA023499B1 (ru) 2016-06-30
KR20100053551A (ko) 2010-05-20
BRPI0813619A2 (pt) 2020-01-14
EP2185588B9 (en) 2012-03-21
JP5441904B2 (ja) 2014-03-12
AU2008286026A1 (en) 2009-02-12
KR101516451B1 (ko) 2015-04-30
DE602008005901D1 (de) 2011-05-12
AU2008286026B2 (en) 2013-11-21
US8148492B2 (en) 2012-04-03
CN101827861A (zh) 2010-09-08

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM