CH676121A5 - - Google Patents

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Publication number
CH676121A5
CH676121A5 CH1228/88A CH122888A CH676121A5 CH 676121 A5 CH676121 A5 CH 676121A5 CH 1228/88 A CH1228/88 A CH 1228/88A CH 122888 A CH122888 A CH 122888A CH 676121 A5 CH676121 A5 CH 676121A5
Authority
CH
Switzerland
Prior art keywords
beta
purinyl
alkyl
desoxy
methyl
Prior art date
Application number
CH1228/88A
Other languages
German (de)
English (en)
Inventor
Fulvio Dr Gadient
Arnold Dr Vogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CH676121A5 publication Critical patent/CH676121A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1228/88A 1987-04-06 1988-03-31 CH676121A5 (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711561 1987-04-06
DE3711562 1987-04-06
DE3711564 1987-04-06
DE3711563 1987-04-06

Publications (1)

Publication Number Publication Date
CH676121A5 true CH676121A5 (it) 1990-12-14

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1228/88A CH676121A5 (it) 1987-04-06 1988-03-31

Country Status (22)

Country Link
JP (1) JPS63258892A (it)
KR (1) KR880012629A (it)
AT (1) AT393507B (it)
AU (1) AU609109B2 (it)
BE (1) BE1002151A5 (it)
CA (1) CA1326017C (it)
CH (1) CH676121A5 (it)
DK (1) DK183488A (it)
ES (1) ES2007177A6 (it)
FI (1) FI87463C (it)
FR (1) FR2613367A1 (it)
GB (1) GB2203149B (it)
HU (1) HU201955B (it)
IL (1) IL85969A (it)
IT (1) IT1219892B (it)
LU (1) LU87181A1 (it)
MY (1) MY102323A (it)
NL (1) NL8800862A (it)
NZ (1) NZ224131A (it)
PH (1) PH25424A (it)
PT (1) PT87153B (it)
SE (1) SE8801236A0 (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
EA200001224A1 (ru) 1998-06-23 2001-08-27 Глаксо Груп Лимитед Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
WO2000063703A1 (en) 1999-04-16 2000-10-26 Schering Corporation Use of azetidinone compounds
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
JP5011112B2 (ja) * 2004-09-20 2012-08-29 イノテック ファーマシューティカルズ コーポレイション プリン誘導体を含有する炎症性疾患の治療用医薬
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida

Also Published As

Publication number Publication date
FI87463B (fi) 1992-09-30
SE8801236L (sv) 1988-10-17
IT8847794A0 (it) 1988-03-30
FI881571A0 (fi) 1988-04-05
IL85969A0 (en) 1988-09-30
NZ224131A (en) 1991-12-23
FR2613367A1 (fr) 1988-10-07
SE8801236A0 (sv) 1988-10-17
GB2203149B (en) 1991-02-13
LU87181A1 (fr) 1988-11-17
DK183488A (da) 1988-10-07
ES2007177A6 (es) 1989-06-01
JPS63258892A (ja) 1988-10-26
KR880012629A (ko) 1988-11-28
DK183488D0 (da) 1988-04-05
NL8800862A (nl) 1988-11-01
FI87463C (fi) 1993-01-11
PH25424A (it) 1991-07-01
CA1326017C (en) 1994-01-11
GB2203149A (en) 1988-10-12
BE1002151A5 (fr) 1990-08-07
PT87153B (pt) 1992-07-31
ATA87388A (de) 1991-04-15
AT393507B (de) 1991-11-11
GB8807750D0 (en) 1988-05-05
IL85969A (en) 1992-03-29
HUT48902A (en) 1989-07-28
SE8801236D0 (sv) 1988-04-05
PT87153A (pt) 1988-05-01
MY102323A (en) 1992-05-28
FI881571A (fi) 1988-10-07
AU1415188A (en) 1988-10-06
IT1219892B (it) 1990-05-24
HU201955B (en) 1991-01-28
AU609109B2 (en) 1991-04-26

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Legal Events

Date Code Title Description
PL Patent ceased