MY102323A - New ribofuranuronic acid derivatives - Google Patents

New ribofuranuronic acid derivatives

Info

Publication number
MY102323A
MY102323A MYPI88000344A MYPI19880344A MY102323A MY 102323 A MY102323 A MY 102323A MY PI88000344 A MYPI88000344 A MY PI88000344A MY PI19880344 A MYPI19880344 A MY PI19880344A MY 102323 A MY102323 A MY 102323A
Authority
MY
Malaysia
Prior art keywords
new
acid derivatives
ribofuranuronic acid
ribofuranuronic
desoxy
Prior art date
Application number
MYPI88000344A
Inventor
Arnold Vogel Dr
Fulvio Gadient Dr
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of MY102323A publication Critical patent/MY102323A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

IN POSITION 2 SUBSTITUTED 1''-DESOXY-1''-(6-AMINO-9-PURINYL)-D-RIBOFURANURONIC ACID AMIDES AND THIOAMIDES OF FORMULA WHEREIN R1, R2, R3, R6 AND X-POSSESS VARIOUS DEFINITIONS GIVEN IN CLAIM 2, ARE EFFECTIVE AGAINST RAISED BLOOD PRESSURE.
MYPI88000344A 1987-04-06 1988-04-04 New ribofuranuronic acid derivatives MY102323A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711561 1987-04-06
DE3711564 1987-04-06
DE3711562 1987-04-06
DE3711563 1987-04-06

Publications (1)

Publication Number Publication Date
MY102323A true MY102323A (en) 1992-05-28

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88000344A MY102323A (en) 1987-04-06 1988-04-04 New ribofuranuronic acid derivatives

Country Status (22)

Country Link
JP (1) JPS63258892A (en)
KR (1) KR880012629A (en)
AT (1) AT393507B (en)
AU (1) AU609109B2 (en)
BE (1) BE1002151A5 (en)
CA (1) CA1326017C (en)
CH (1) CH676121A5 (en)
DK (1) DK183488A (en)
ES (1) ES2007177A6 (en)
FI (1) FI87463C (en)
FR (1) FR2613367A1 (en)
GB (1) GB2203149B (en)
HU (1) HU201955B (en)
IL (1) IL85969A (en)
IT (1) IT1219892B (en)
LU (1) LU87181A1 (en)
MY (1) MY102323A (en)
NL (1) NL8800862A (en)
NZ (1) NZ224131A (en)
PH (1) PH25424A (en)
PT (1) PT87153B (en)
SE (1) SE8801236L (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (en) * 1992-04-24 1995-10-11 Gloria Cristalli ADENOSINE DERIVATIVES FOR ACTIVITY A2 AGONIST
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (en) 1998-01-31 2003-01-31 Glaxo Group Limited 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
CN1313861A (en) 1998-06-23 2001-09-19 葛兰素集团有限公司 2-(purin-9-YL)-tetrahydrofuran-3,4-diolderivatives
AU4343500A (en) 1999-04-16 2000-11-02 Schering Corporation Use of azetidinone compounds
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (en) 2004-05-24 2006-07-26 Glaxo Group Ltd PURINA DERIVATIVES
EP1802316B1 (en) * 2004-09-20 2011-11-02 Inotek Pharmaceuticals Corporation Purine derivatives and methods of use thereof
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (en) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim USE OF ADENOSINE DERIVATIVES AS ANTIALLERGICA AND MEDICINAL PRODUCTS CONTAINING THEM
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives

Also Published As

Publication number Publication date
HU201955B (en) 1991-01-28
NZ224131A (en) 1991-12-23
FI881571A (en) 1988-10-07
AT393507B (en) 1991-11-11
SE8801236D0 (en) 1988-04-05
IL85969A (en) 1992-03-29
DK183488A (en) 1988-10-07
FI881571A0 (en) 1988-04-05
KR880012629A (en) 1988-11-28
SE8801236A0 (en) 1988-10-17
JPS63258892A (en) 1988-10-26
IT1219892B (en) 1990-05-24
FI87463B (en) 1992-09-30
AU609109B2 (en) 1991-04-26
PH25424A (en) 1991-07-01
IT8847794A0 (en) 1988-03-30
FR2613367A1 (en) 1988-10-07
HUT48902A (en) 1989-07-28
CA1326017C (en) 1994-01-11
CH676121A5 (en) 1990-12-14
NL8800862A (en) 1988-11-01
LU87181A1 (en) 1988-11-17
PT87153A (en) 1988-05-01
SE8801236L (en) 1988-10-17
AU1415188A (en) 1988-10-06
GB2203149A (en) 1988-10-12
FI87463C (en) 1993-01-11
ATA87388A (en) 1991-04-15
PT87153B (en) 1992-07-31
GB8807750D0 (en) 1988-05-05
GB2203149B (en) 1991-02-13
IL85969A0 (en) 1988-09-30
DK183488D0 (en) 1988-04-05
BE1002151A5 (en) 1990-08-07
ES2007177A6 (en) 1989-06-01

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