BE1002151A5 - NOVEL DERIVATIVES OF FURANNURONIC ACID, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS. - Google Patents

NOVEL DERIVATIVES OF FURANNURONIC ACID, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS. Download PDF

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Publication number
BE1002151A5
BE1002151A5 BE8800374A BE8800374A BE1002151A5 BE 1002151 A5 BE1002151 A5 BE 1002151A5 BE 8800374 A BE8800374 A BE 8800374A BE 8800374 A BE8800374 A BE 8800374A BE 1002151 A5 BE1002151 A5 BE 1002151A5
Authority
BE
Belgium
Prior art keywords
medicaments
furannuronic
preparation
acid
novel derivatives
Prior art date
Application number
BE8800374A
Other languages
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Application granted granted Critical
Publication of BE1002151A5 publication Critical patent/BE1002151A5/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention a pour objet des amides et thioamides d'un acide 1'-désoxy-1'-(6-amino-9-purinyl)-beta-D-ribofurannuronique substitué en position 2. Ces composés peuvent être utilisés comme médicaments.The subject of the invention is amides and thioamides of an 1'-deoxy-1 '- (6-amino-9-purinyl) -beta-D-ribofuranuronic acid substituted in position 2. These compounds can be used as medicaments.

BE8800374A 1987-04-06 1988-03-30 NOVEL DERIVATIVES OF FURANNURONIC ACID, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS. BE1002151A5 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711564 1987-04-06
DE3711563 1987-04-06
DE3711561 1987-04-06
DE3711562 1987-04-06

Publications (1)

Publication Number Publication Date
BE1002151A5 true BE1002151A5 (en) 1990-08-07

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8800374A BE1002151A5 (en) 1987-04-06 1988-03-30 NOVEL DERIVATIVES OF FURANNURONIC ACID, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS.

Country Status (22)

Country Link
JP (1) JPS63258892A (en)
KR (1) KR880012629A (en)
AT (1) AT393507B (en)
AU (1) AU609109B2 (en)
BE (1) BE1002151A5 (en)
CA (1) CA1326017C (en)
CH (1) CH676121A5 (en)
DK (1) DK183488A (en)
ES (1) ES2007177A6 (en)
FI (1) FI87463C (en)
FR (1) FR2613367A1 (en)
GB (1) GB2203149B (en)
HU (1) HU201955B (en)
IL (1) IL85969A (en)
IT (1) IT1219892B (en)
LU (1) LU87181A1 (en)
MY (1) MY102323A (en)
NL (1) NL8800862A (en)
NZ (1) NZ224131A (en)
PH (1) PH25424A (en)
PT (1) PT87153B (en)
SE (1) SE8801236A0 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
FI880405A (en) * 1987-02-04 1988-08-05 Ciba Geigy Ag Adenosine-5'-KARBOXAMIDDERIVAT.
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (en) * 1992-04-24 1995-10-11 Gloria Cristalli ADENOSINE DERIVATIVES FOR ACTIVITY A2 AGONIST
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (en) 1998-01-31 2003-01-31 Glaxo Group Limited 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
KR20010071591A (en) 1998-06-23 2001-07-28 그레이엄 브레레톤, 레슬리 에드워즈 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
US6593078B1 (en) 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (en) 2004-05-24 2006-07-26 Glaxo Group Ltd PURINA DERIVATIVES
EP1802316B1 (en) * 2004-09-20 2011-11-02 Inotek Pharmaceuticals Corporation Purine derivatives and methods of use thereof
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
EP0277917A2 (en) * 1987-02-04 1988-08-10 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
DE3406533A1 (en) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim USE OF ADENOSINE DERIVATIVES AS ANTIALLERGICA AND MEDICINAL PRODUCTS CONTAINING THEM
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
EP0277917A2 (en) * 1987-02-04 1988-08-10 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives

Also Published As

Publication number Publication date
PT87153A (en) 1988-05-01
FI881571A0 (en) 1988-04-05
CH676121A5 (en) 1990-12-14
MY102323A (en) 1992-05-28
PT87153B (en) 1992-07-31
LU87181A1 (en) 1988-11-17
SE8801236L (en) 1988-10-17
CA1326017C (en) 1994-01-11
ES2007177A6 (en) 1989-06-01
NZ224131A (en) 1991-12-23
HU201955B (en) 1991-01-28
KR880012629A (en) 1988-11-28
SE8801236D0 (en) 1988-04-05
AU609109B2 (en) 1991-04-26
DK183488A (en) 1988-10-07
ATA87388A (en) 1991-04-15
AT393507B (en) 1991-11-11
FI881571A (en) 1988-10-07
SE8801236A0 (en) 1988-10-17
IL85969A (en) 1992-03-29
FI87463C (en) 1993-01-11
IL85969A0 (en) 1988-09-30
FI87463B (en) 1992-09-30
GB2203149A (en) 1988-10-12
DK183488D0 (en) 1988-04-05
JPS63258892A (en) 1988-10-26
GB2203149B (en) 1991-02-13
GB8807750D0 (en) 1988-05-05
NL8800862A (en) 1988-11-01
IT1219892B (en) 1990-05-24
AU1415188A (en) 1988-10-06
FR2613367A1 (en) 1988-10-07
PH25424A (en) 1991-07-01
IT8847794A0 (en) 1988-03-30
HUT48902A (en) 1989-07-28

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: S.A. SANDOZ

Effective date: 19950331