CH661927A5 - Carbapenem-antibiotika. - Google Patents

Carbapenem-antibiotika. Download PDF

Info

Publication number
CH661927A5
CH661927A5 CH1915/83A CH191583A CH661927A5 CH 661927 A5 CH661927 A5 CH 661927A5 CH 1915/83 A CH1915/83 A CH 1915/83A CH 191583 A CH191583 A CH 191583A CH 661927 A5 CH661927 A5 CH 661927A5
Authority
CH
Switzerland
Prior art keywords
alkyl
group
formula
compound
alkylamino
Prior art date
Application number
CH1915/83A
Other languages
German (de)
English (en)
Inventor
Choung Un Kim
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH661927A5 publication Critical patent/CH661927A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH1915/83A 1982-04-08 1983-04-08 Carbapenem-antibiotika. CH661927A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36662782A 1982-04-08 1982-04-08

Publications (1)

Publication Number Publication Date
CH661927A5 true CH661927A5 (de) 1987-08-31

Family

ID=23443823

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1915/83A CH661927A5 (de) 1982-04-08 1983-04-08 Carbapenem-antibiotika.

Country Status (25)

Country Link
JP (1) JPS58188887A (sv)
KR (1) KR880001055B1 (sv)
AT (1) AT383126B (sv)
AU (1) AU567092B2 (sv)
BE (1) BE896407A (sv)
CA (1) CA1198440A (sv)
CH (1) CH661927A5 (sv)
DE (1) DE3312517A1 (sv)
DK (1) DK155983A (sv)
ES (1) ES8405399A1 (sv)
FI (1) FI74009C (sv)
FR (1) FR2524888B1 (sv)
GB (1) GB2118183B (sv)
GR (1) GR78822B (sv)
HU (1) HU190716B (sv)
IE (1) IE55225B1 (sv)
IL (1) IL68295A0 (sv)
IT (1) IT1168854B (sv)
LU (1) LU84739A1 (sv)
MY (1) MY8700945A (sv)
NL (1) NL8301193A (sv)
OA (1) OA07395A (sv)
PT (1) PT76518B (sv)
SE (1) SE460197B (sv)
ZA (1) ZA832411B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
AT396473B (de) * 1984-10-02 1993-09-27 Bristol Myers Squibb Co Verfahren zur herstellung von neuen carbapenemderivaten
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
HU185493B (en) * 1981-12-30 1985-02-28 Richter Gedeon Vegyeszet Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics

Also Published As

Publication number Publication date
IT1168854B (it) 1987-05-20
DK155983D0 (da) 1983-04-07
ATA125583A (de) 1986-10-15
GB8309505D0 (en) 1983-05-11
GB2118183B (en) 1985-11-27
GB2118183A (en) 1983-10-26
ZA832411B (en) 1983-12-28
ES521224A0 (es) 1984-06-01
PT76518A (en) 1983-05-01
DE3312517A1 (de) 1983-10-20
FI74009B (fi) 1987-08-31
IE55225B1 (en) 1990-07-04
MY8700945A (en) 1987-12-31
AU567092B2 (en) 1987-11-12
JPS58188887A (ja) 1983-11-04
CA1198440A (en) 1985-12-24
KR840004429A (ko) 1984-10-15
SE460197B (sv) 1989-09-18
AU1319883A (en) 1983-10-13
FI74009C (sv) 1987-12-10
KR880001055B1 (ko) 1988-06-18
PT76518B (en) 1986-02-06
HU190716B (en) 1986-10-28
ES8405399A1 (es) 1984-06-01
FR2524888A1 (fr) 1983-10-14
IE830800L (en) 1983-10-08
IL68295A0 (en) 1983-07-31
NL8301193A (nl) 1983-11-01
JPH0524156B2 (sv) 1993-04-06
DE3312517C2 (sv) 1991-10-31
IT8348061A0 (it) 1983-04-07
SE8301928L (sv) 1983-12-02
FI831135A0 (fi) 1983-04-05
OA07395A (fr) 1984-06-30
LU84739A1 (fr) 1983-12-05
FI831135L (fi) 1983-10-09
BE896407A (fr) 1983-10-07
GR78822B (sv) 1984-10-02
DK155983A (da) 1983-10-09
SE8301928D0 (sv) 1983-04-07
AT383126B (de) 1987-05-25
FR2524888B1 (fr) 1985-12-13

Similar Documents

Publication Publication Date Title
DE3587126T2 (de) Carbapenem-Derivate und sie enthaltende Zusammensetzung.
DE69429742T2 (de) 2-[1-(1,3-Thiazolin-2-yl)azetidin-3-yl]thio-carbapenem-Derivate
DE3321864C2 (sv)
CH657853A5 (de) Carbapenemderivate, deren herstellung und solche verbindungen enthaltende praeparate.
DE69129175T2 (de) 1-Methylcarbapenemderivate und Verfahren zu ihrer Herstellung
DE3334937C2 (sv)
DE3587112T2 (de) 2-quaternaer-pyridinalkylthio- oder -pyridinalkenylthiosubstituierte carbapeneme, diese enthaltende zusammensetzungen und ihre zusammenstellungen mit dhp-inhibitoren.
DE68916908T2 (de) Carbapenemderivate.
AT395590B (de) 2-methoxymethylpenemverbindungen, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE3312517C2 (sv)
DE3317742C2 (sv)
DE69218843T2 (de) Aminooxypyrrolidinylthiocarbapenem-Verbindungen
AT397090B (de) Verfahren zur herstellung von neuen carbapenemderivaten
DE69523058T2 (de) Carbapenem-derivate
AT395151B (de) Verfahren zur herstellung von neuen carbapenemderivaten
AT396472B (de) Verfahren zur herstellung neuer carbapenem-antibiotika
AT387388B (de) Verfahren zur herstellung von neuen carbapenem-antibiotika
CH633800A5 (en) Process for the preparation of guanidines
DE69909098T2 (de) C-2 s/o- und s/n-formaldehydacetal-derivate von carbapenem-3-carbonsäuren und deren verwendung als antibiotika und beta-lactamas-inhibitoren
CH633554A5 (en) Process for the preparation of novel thienamycin derivatives.
AT381942B (de) Verfahren zur herstellung neuer carbapenem-derivate
AT396473B (de) Verfahren zur herstellung von neuen carbapenemderivaten
AT387574B (de) Verfahren zur herstellung neuer carbapenem-derivate
AT387575B (de) Verfahren zur herstellung neuer carbapenem-derivate
CH671580A5 (sv)

Legal Events

Date Code Title Description
PL Patent ceased