IT1168854B - Derivati di carbapenem dotati di attivita' antibiotica e procedimento per la loro preparazione - Google Patents

Derivati di carbapenem dotati di attivita' antibiotica e procedimento per la loro preparazione

Info

Publication number
IT1168854B
IT1168854B IT48061/83A IT4806183A IT1168854B IT 1168854 B IT1168854 B IT 1168854B IT 48061/83 A IT48061/83 A IT 48061/83A IT 4806183 A IT4806183 A IT 4806183A IT 1168854 B IT1168854 B IT 1168854B
Authority
IT
Italy
Prior art keywords
procedure
preparation
antibiotic activity
carbapenem derivatives
derivatives equipped
Prior art date
Application number
IT48061/83A
Other languages
English (en)
Other versions
IT8348061A0 (it
Inventor
Choung Un Kim
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8348061A0 publication Critical patent/IT8348061A0/it
Application granted granted Critical
Publication of IT1168854B publication Critical patent/IT1168854B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT48061/83A 1982-04-08 1983-04-07 Derivati di carbapenem dotati di attivita' antibiotica e procedimento per la loro preparazione IT1168854B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36662782A 1982-04-08 1982-04-08

Publications (2)

Publication Number Publication Date
IT8348061A0 IT8348061A0 (it) 1983-04-07
IT1168854B true IT1168854B (it) 1987-05-20

Family

ID=23443823

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48061/83A IT1168854B (it) 1982-04-08 1983-04-07 Derivati di carbapenem dotati di attivita' antibiotica e procedimento per la loro preparazione

Country Status (25)

Country Link
JP (1) JPS58188887A (it)
KR (1) KR880001055B1 (it)
AT (1) AT383126B (it)
AU (1) AU567092B2 (it)
BE (1) BE896407A (it)
CA (1) CA1198440A (it)
CH (1) CH661927A5 (it)
DE (1) DE3312517A1 (it)
DK (1) DK155983A (it)
ES (1) ES8405399A1 (it)
FI (1) FI74009C (it)
FR (1) FR2524888B1 (it)
GB (1) GB2118183B (it)
GR (1) GR78822B (it)
HU (1) HU190716B (it)
IE (1) IE55225B1 (it)
IL (1) IL68295A0 (it)
IT (1) IT1168854B (it)
LU (1) LU84739A1 (it)
MY (1) MY8700945A (it)
NL (1) NL8301193A (it)
OA (1) OA07395A (it)
PT (1) PT76518B (it)
SE (1) SE460197B (it)
ZA (1) ZA832411B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
AT396473B (de) * 1984-10-02 1993-09-27 Bristol Myers Squibb Co Verfahren zur herstellung von neuen carbapenemderivaten
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
HU185493B (en) * 1981-12-30 1985-02-28 Richter Gedeon Vegyeszet Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics

Also Published As

Publication number Publication date
SE8301928L (sv) 1983-12-02
SE460197B (sv) 1989-09-18
JPH0524156B2 (it) 1993-04-06
CH661927A5 (de) 1987-08-31
KR880001055B1 (ko) 1988-06-18
AU567092B2 (en) 1987-11-12
OA07395A (fr) 1984-06-30
IL68295A0 (en) 1983-07-31
DE3312517A1 (de) 1983-10-20
MY8700945A (en) 1987-12-31
ATA125583A (de) 1986-10-15
PT76518A (en) 1983-05-01
GR78822B (it) 1984-10-02
GB2118183A (en) 1983-10-26
LU84739A1 (fr) 1983-12-05
GB2118183B (en) 1985-11-27
BE896407A (fr) 1983-10-07
DK155983A (da) 1983-10-09
AU1319883A (en) 1983-10-13
NL8301193A (nl) 1983-11-01
ZA832411B (en) 1983-12-28
FI74009C (fi) 1987-12-10
HU190716B (en) 1986-10-28
FI74009B (fi) 1987-08-31
CA1198440A (en) 1985-12-24
FI831135L (fi) 1983-10-09
GB8309505D0 (en) 1983-05-11
IT8348061A0 (it) 1983-04-07
JPS58188887A (ja) 1983-11-04
AT383126B (de) 1987-05-25
DE3312517C2 (it) 1991-10-31
ES521224A0 (es) 1984-06-01
DK155983D0 (da) 1983-04-07
IE830800L (en) 1983-10-08
PT76518B (en) 1986-02-06
ES8405399A1 (es) 1984-06-01
IE55225B1 (en) 1990-07-04
FI831135A0 (fi) 1983-04-05
SE8301928D0 (sv) 1983-04-07
KR840004429A (ko) 1984-10-15
FR2524888B1 (fr) 1985-12-13
FR2524888A1 (fr) 1983-10-14

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