IT8747874A0 - La loro preparazione derivati tiodiossolanici ad attivita' moculitica e procedimento per - Google Patents
La loro preparazione derivati tiodiossolanici ad attivita' moculitica e procedimento perInfo
- Publication number
- IT8747874A0 IT8747874A0 IT8747874A IT4787487A IT8747874A0 IT 8747874 A0 IT8747874 A0 IT 8747874A0 IT 8747874 A IT8747874 A IT 8747874A IT 4787487 A IT4787487 A IT 4787487A IT 8747874 A0 IT8747874 A0 IT 8747874A0
- Authority
- IT
- Italy
- Prior art keywords
- thiodioxolane
- moculitic
- derivatives
- activity
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT47874/87A IT1205834B (it) | 1987-04-22 | 1987-04-22 | Derivati tiodiossolanici ad attivita' mucolitica a procedimento per la loro preparazione |
| EP88106192A EP0288871A3 (en) | 1987-04-22 | 1988-04-19 | Pharmaceutical compositions containing thio-dioxolane derivatives having mucolytic activity |
| US07/184,057 US4910220A (en) | 1987-04-22 | 1988-04-20 | Pharmaceutical compositions containing thio-dioxolane derivatives having mucolytic activity |
| JP63098406A JPS6413022A (en) | 1987-04-22 | 1988-04-22 | Drug composition containing mucolytic thio-dioxolane derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT47874/87A IT1205834B (it) | 1987-04-22 | 1987-04-22 | Derivati tiodiossolanici ad attivita' mucolitica a procedimento per la loro preparazione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8747874A0 true IT8747874A0 (it) | 1987-04-22 |
| IT1205834B IT1205834B (it) | 1989-03-31 |
Family
ID=11263057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT47874/87A IT1205834B (it) | 1987-04-22 | 1987-04-22 | Derivati tiodiossolanici ad attivita' mucolitica a procedimento per la loro preparazione |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4910220A (it) |
| EP (1) | EP0288871A3 (it) |
| JP (1) | JPS6413022A (it) |
| IT (1) | IT1205834B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2638457B1 (fr) * | 1988-11-02 | 1994-05-06 | Merieux Institut | Procede de synthese specifique d'esters d'acides dithiocarbamiques par substitution de sites hydroxyles sur des molecules mono- ou polyhydroxylees, produits obtenus par ce procede et leurs applications |
| US5283346A (en) * | 1989-03-23 | 1994-02-01 | Hoffmann-La Roche Inc. | Dioxolanes |
| KR100966749B1 (ko) * | 2004-05-26 | 2010-06-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물 |
| CN100577657C (zh) | 2004-10-26 | 2010-01-06 | 卫材R&D管理有限公司 | 肉桂酰胺化合物的无定形物 |
| AU2006316005A1 (en) * | 2005-11-18 | 2007-05-24 | Eisai R & D Management Co., Ltd. | Process for production of cinnamamide derivative |
| EP1953151A4 (en) * | 2005-11-18 | 2010-06-02 | Eisai R&D Man Co Ltd | SALTS FROM A CYNNAMIDE COMPOUND OR SOLVATE THEREOF |
| TWI370130B (en) * | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
| WO2008140111A1 (ja) * | 2007-05-16 | 2008-11-20 | Eisai R & D Management Co., Ltd. | シンナミド誘導体のワンポット製造方法 |
| WO2009096349A1 (ja) * | 2008-01-28 | 2009-08-06 | Eisai R & D Management Co., Ltd. | 結晶性のシンナミド化合物またはその塩 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4588824A (en) * | 1982-04-19 | 1986-05-13 | Merck & Co., Inc. | Preparation of epihalohydrin enantiomers |
| US4575558A (en) * | 1984-02-15 | 1986-03-11 | American Hospital Supply Corporation | Preparation of optically active 1,3-dioxolane-4-methanol compounds |
| FR2577552B1 (fr) * | 1985-02-20 | 1987-09-04 | Sori Soc Rech Ind | Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique |
| US4686234A (en) * | 1985-11-27 | 1987-08-11 | Syntex (U.S.A) Inc. | Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis |
-
1987
- 1987-04-22 IT IT47874/87A patent/IT1205834B/it active
-
1988
- 1988-04-19 EP EP88106192A patent/EP0288871A3/en not_active Withdrawn
- 1988-04-20 US US07/184,057 patent/US4910220A/en not_active Expired - Fee Related
- 1988-04-22 JP JP63098406A patent/JPS6413022A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0288871A3 (en) | 1990-05-16 |
| JPS6413022A (en) | 1989-01-17 |
| IT1205834B (it) | 1989-03-31 |
| US4910220A (en) | 1990-03-20 |
| EP0288871A2 (en) | 1988-11-02 |
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