CH645631A5 - Process for the preparation of hydantoin derivatives - Google Patents

Process for the preparation of hydantoin derivatives Download PDF

Info

Publication number
CH645631A5
CH645631A5 CH679677A CH679677A CH645631A5 CH 645631 A5 CH645631 A5 CH 645631A5 CH 679677 A CH679677 A CH 679677A CH 679677 A CH679677 A CH 679677A CH 645631 A5 CH645631 A5 CH 645631A5
Authority
CH
Switzerland
Prior art keywords
group
hydantoin
hydroxy
formula
hydrogen
Prior art date
Application number
CH679677A
Other languages
German (de)
English (en)
Inventor
Gordon Caldwell Albert
Whittaker Norman
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CH645631A5 publication Critical patent/CH645631A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH679677A 1976-06-03 1977-06-02 Process for the preparation of hydantoin derivatives CH645631A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2287776 1976-06-03
GB5034076 1976-12-02
GB1214577 1977-03-23

Publications (1)

Publication Number Publication Date
CH645631A5 true CH645631A5 (en) 1984-10-15

Family

ID=27256793

Family Applications (3)

Application Number Title Priority Date Filing Date
CH679677A CH645631A5 (en) 1976-06-03 1977-06-02 Process for the preparation of hydantoin derivatives
CH576/84A CH647511A5 (en) 1976-06-03 1984-02-07 Process for the preparation of hydantoin derivatives
CH57784A CH646426A5 (en) 1976-06-03 1984-02-07 Process for the preparation of hydantoin derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH576/84A CH647511A5 (en) 1976-06-03 1984-02-07 Process for the preparation of hydantoin derivatives
CH57784A CH646426A5 (en) 1976-06-03 1984-02-07 Process for the preparation of hydantoin derivatives

Country Status (12)

Country Link
JP (1) JPS52151168A (da)
CA (1) CA1176261A (da)
CH (3) CH645631A5 (da)
DE (1) DE2724948A1 (da)
DK (1) DK244577A (da)
ES (5) ES459412A1 (da)
FI (1) FI71930C (da)
FR (1) FR2362839A1 (da)
HU (1) HU183046B (da)
NL (1) NL7706064A (da)
NZ (1) NZ184281A (da)
SE (2) SE446336B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
AU527959B2 (en) * 1977-09-05 1983-03-31 Wellcome Foundation Limited, The Hydantoin derivatives
DK543178A (da) * 1977-12-01 1979-06-02 Wellcome Found Thiodydantoinderivater
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
EP0007180B1 (en) * 1978-06-15 1983-03-30 Beecham Group Plc Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them
IL59065A0 (en) * 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
JPS55151569A (en) * 1979-05-09 1980-11-26 Wellcome Found Optically active heterocyclic compounds* their synthesis and medical blend containing them
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JP3022878U (ja) * 1995-08-18 1996-04-02 有限会社春江加工 ミニディスク用ケース
MXPA04005123A (es) * 2001-11-30 2005-02-17 Lilly Co Eli Agonistas del receptor activado por proliferador de peroxisoma.
CA2528179C (en) * 2003-06-06 2013-10-22 Allergan, Inc. Piperidinyl prostaglandin e analogs
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
ES459412A1 (es) 1978-11-01
FI71930C (fi) 1987-03-09
ES8103057A1 (es) 1981-02-16
ES489883A0 (es) 1981-02-16
CH646426A5 (en) 1984-11-30
NL7706064A (nl) 1977-12-06
HU183046B (en) 1984-04-28
SE7706428L (sv) 1977-12-04
ES470428A1 (es) 1979-09-01
FR2362839B1 (da) 1980-02-01
DK244577A (da) 1977-12-04
DE2724948A1 (de) 1977-12-15
CA1176261A (en) 1984-10-16
JPS52151168A (en) 1977-12-15
NZ184281A (en) 1980-04-28
SE8203161L (sv) 1982-05-19
FR2362839A1 (fr) 1978-03-24
SE446336B (sv) 1986-09-01
ES478156A1 (es) 1979-11-01
JPS6222986B2 (da) 1987-05-20
FI71930B (fi) 1986-11-28
FI771763A (fi) 1977-12-04
CH647511A5 (en) 1985-01-31
ES482010A1 (es) 1980-08-16

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