FI71930C - Foerfarande foer framstaellning av 1,5-disubstituerad hydantoin med aggregation av blodkroppar foerhindrande verkan. - Google Patents

Foerfarande foer framstaellning av 1,5-disubstituerad hydantoin med aggregation av blodkroppar foerhindrande verkan. Download PDF

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Publication number
FI71930C
FI71930C FI771763A FI771763A FI71930C FI 71930 C FI71930 C FI 71930C FI 771763 A FI771763 A FI 771763A FI 771763 A FI771763 A FI 771763A FI 71930 C FI71930 C FI 71930C
Authority
FI
Finland
Prior art keywords
group
formula
hydantoin
compound
diethyl
Prior art date
Application number
FI771763A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI771763A (fi
FI71930B (fi
Inventor
Albert Gordon Caldwell
Norman Whittaker
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI771763A publication Critical patent/FI771763A/fi
Application granted granted Critical
Publication of FI71930B publication Critical patent/FI71930B/fi
Publication of FI71930C publication Critical patent/FI71930C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI771763A 1976-06-03 1977-06-02 Foerfarande foer framstaellning av 1,5-disubstituerad hydantoin med aggregation av blodkroppar foerhindrande verkan. FI71930C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB2287776 1976-06-03
GB2287776 1976-06-03
GB5034076 1976-12-02
GB5034076 1976-12-02
GB1214577 1977-03-23
GB1214577 1977-03-23

Publications (3)

Publication Number Publication Date
FI771763A FI771763A (fi) 1977-12-04
FI71930B FI71930B (fi) 1986-11-28
FI71930C true FI71930C (fi) 1987-03-09

Family

ID=27256793

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771763A FI71930C (fi) 1976-06-03 1977-06-02 Foerfarande foer framstaellning av 1,5-disubstituerad hydantoin med aggregation av blodkroppar foerhindrande verkan.

Country Status (12)

Country Link
JP (1) JPS52151168A (da)
CA (1) CA1176261A (da)
CH (3) CH645631A5 (da)
DE (1) DE2724948A1 (da)
DK (1) DK244577A (da)
ES (5) ES459412A1 (da)
FI (1) FI71930C (da)
FR (1) FR2362839A1 (da)
HU (1) HU183046B (da)
NL (1) NL7706064A (da)
NZ (1) NZ184281A (da)
SE (2) SE446336B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
AT372681B (de) * 1977-09-05 1983-11-10 Wellcome Found Verfahren zur herstellung von neuen 1,5-disubstituierter hydantoinen
JPS5492962A (en) * 1977-12-01 1979-07-23 Wellcome Found Thiohydantoin compound
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
CA1122222A (en) * 1978-06-15 1982-04-20 Frederick Cassidy Novel 1,2,4-triazolidine-3,5-dione derivatives
IL59065A0 (en) * 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
GB2050371A (en) * 1979-05-09 1981-01-07 Wellcome Found Optically active hydantoin derivatives and pharmaceutical formulations containing them
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JP3022878U (ja) * 1995-08-18 1996-04-02 有限会社春江加工 ミニディスク用ケース
CA2468846A1 (en) 2001-11-30 2003-06-12 Eli Lilly And Company Peroxisome proliferator activated receptor agonists
BRPI0411057A (pt) * 2003-06-06 2006-07-25 Allergan Inc análogos de prostaglandina e de piperidinila
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
DK244577A (da) 1977-12-04
CH647511A5 (en) 1985-01-31
CH645631A5 (en) 1984-10-15
ES489883A0 (es) 1981-02-16
HU183046B (en) 1984-04-28
JPS52151168A (en) 1977-12-15
SE7706428L (sv) 1977-12-04
ES478156A1 (es) 1979-11-01
FR2362839B1 (da) 1980-02-01
SE446336B (sv) 1986-09-01
FI771763A (fi) 1977-12-04
CH646426A5 (en) 1984-11-30
ES470428A1 (es) 1979-09-01
SE8203161L (sv) 1982-05-19
ES459412A1 (es) 1978-11-01
FR2362839A1 (fr) 1978-03-24
JPS6222986B2 (da) 1987-05-20
ES8103057A1 (es) 1981-02-16
FI71930B (fi) 1986-11-28
DE2724948A1 (de) 1977-12-15
ES482010A1 (es) 1980-08-16
CA1176261A (en) 1984-10-16
NZ184281A (en) 1980-04-28
NL7706064A (nl) 1977-12-06

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MM Patent lapsed

Owner name: THE WELLCOME FOUNDATION LIMITED