ES470428A1 - Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina - Google Patents
Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoinaInfo
- Publication number
- ES470428A1 ES470428A1 ES470428A ES470428A ES470428A1 ES 470428 A1 ES470428 A1 ES 470428A1 ES 470428 A ES470428 A ES 470428A ES 470428 A ES470428 A ES 470428A ES 470428 A1 ES470428 A1 ES 470428A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- heterocyclic compound
- compounds
- symbols
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un método de preparación de compuestos heterocíclicos derivados de hidantoína de formula (I) **(formula)** en la que Z es hidrógeno o alcohilo; uno de Z1 y Z2 está representado por el grupo -CH-X-X1-X2x; en el que X es fenileno, -C=C-, -CH=CH- cis ó trans, ó -CH2-CQ2- donde cada Q se selecciona independientemente de entre hidrógeno y alcohilo o bien los dos grupos Q forman juntos un radical alcohileno que tiene cuatro, cinco o seis átomos de carbono; X1 es un enlace covalente o una cadena de alcohileno recta o ramificada que tiene 1 a 6 átomos de carbono y que tiene opcionalmente uno de sus grupos metileno reemplazado por oxa (-0-) con la condición de que al menos un átomo de carbono separa el grupo oxa de un grupo-C=-, -CH=CH- ó -CO; y X2 se selecciona de entre 5-tetrazolilo, carboxilo, carboxamido, hidroximetileno y alcoxicarbonilo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2287776 | 1976-06-03 | ||
GB5034076 | 1976-12-02 | ||
GB1214577 | 1977-03-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES470428A1 true ES470428A1 (es) | 1979-09-01 |
Family
ID=27256793
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES459412A Expired ES459412A1 (es) | 1976-06-03 | 1977-06-02 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina. |
ES470428A Expired ES470428A1 (es) | 1976-06-03 | 1978-06-01 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina |
ES478156A Expired ES478156A1 (es) | 1976-06-03 | 1979-02-28 | Un metodo de preparacion de compuestos heterociclicos derivados de hidantoina. |
ES482010A Expired ES482010A1 (es) | 1976-06-03 | 1979-06-28 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina. |
ES489883A Expired ES8103057A1 (es) | 1976-06-03 | 1980-03-25 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES459412A Expired ES459412A1 (es) | 1976-06-03 | 1977-06-02 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES478156A Expired ES478156A1 (es) | 1976-06-03 | 1979-02-28 | Un metodo de preparacion de compuestos heterociclicos derivados de hidantoina. |
ES482010A Expired ES482010A1 (es) | 1976-06-03 | 1979-06-28 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina. |
ES489883A Expired ES8103057A1 (es) | 1976-06-03 | 1980-03-25 | Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS52151168A (es) |
CA (1) | CA1176261A (es) |
CH (3) | CH645631A5 (es) |
DE (1) | DE2724948A1 (es) |
DK (1) | DK244577A (es) |
ES (5) | ES459412A1 (es) |
FI (1) | FI71930C (es) |
FR (1) | FR2362839A1 (es) |
HU (1) | HU183046B (es) |
NL (1) | NL7706064A (es) |
NZ (1) | NZ184281A (es) |
SE (2) | SE446336B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1602188A (en) * | 1977-12-01 | 1981-11-11 | Wellcome Found | Hydantoin derivatives |
JPS5463083A (en) * | 1977-09-05 | 1979-05-21 | Wellcome Found | Organism active nitrogen compound |
ZA786739B (en) * | 1977-12-01 | 1980-07-30 | Wellcome Found | Hydantoin derivatives and salts thereof,their syntheses,and intermediates,and pharmaceutical formulations |
DE2963795D1 (en) * | 1978-01-23 | 1982-11-11 | Beecham Group Plc | Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them |
EP0004723A1 (en) * | 1978-03-30 | 1979-10-17 | Beecham Group Plc | Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them |
GB1599740A (en) * | 1978-05-31 | 1981-10-07 | Wellcome Found | Hydantoin derivatives |
IL57504A0 (en) * | 1978-06-15 | 1979-10-31 | Beecham Group Ltd | Prostagandin analogues,their preparation and pharmaceutical compositions containing |
US4294972A (en) * | 1978-06-15 | 1981-10-13 | Beecham Group Limited | 1,2-Disubstituted oxo triazolidine |
EP0006352A1 (en) * | 1978-06-15 | 1980-01-09 | Beecham Group Plc | Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them |
AU4778279A (en) * | 1978-06-15 | 1979-12-20 | Beecham Group Limited | Prostaglandin analogues |
IL59065A0 (en) * | 1979-01-18 | 1980-05-30 | Beecham Group Ltd | Hydantoin derivatives,their preparation pharmaceutical compositons containing them |
GB2050371A (en) * | 1979-05-09 | 1981-01-07 | Wellcome Found | Optically active hydantoin derivatives and pharmaceutical formulations containing them |
US4684735A (en) * | 1985-07-01 | 1987-08-04 | Stauffer Chemical Company | Promotion of raney nickel hydrogenation catalyst |
JP3022878U (ja) * | 1995-08-18 | 1996-04-02 | 有限会社春江加工 | ミニディスク用ケース |
KR20050044606A (ko) * | 2001-11-30 | 2005-05-12 | 일라이 릴리 앤드 캄파니 | 퍼옥시솜 증식제에 의해 활성화된 수용체 아고니스트 |
CA2528179C (en) * | 2003-06-06 | 2013-10-22 | Allergan, Inc. | Piperidinyl prostaglandin e analogs |
US7179820B2 (en) * | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1524818A (en) * | 1974-11-29 | 1978-09-13 | Beecham Group Ltd | 12-azaprostaglandins |
-
1977
- 1977-06-02 DK DK244577A patent/DK244577A/da not_active Application Discontinuation
- 1977-06-02 CA CA000280455A patent/CA1176261A/en not_active Expired
- 1977-06-02 DE DE19772724948 patent/DE2724948A1/de not_active Ceased
- 1977-06-02 CH CH679677A patent/CH645631A5/de not_active IP Right Cessation
- 1977-06-02 ES ES459412A patent/ES459412A1/es not_active Expired
- 1977-06-02 NZ NZ184281A patent/NZ184281A/xx unknown
- 1977-06-02 FR FR7716849A patent/FR2362839A1/fr active Granted
- 1977-06-02 FI FI771763A patent/FI71930C/fi not_active IP Right Cessation
- 1977-06-02 HU HU77WE560A patent/HU183046B/hu unknown
- 1977-06-02 JP JP6525277A patent/JPS52151168A/ja active Granted
- 1977-06-02 SE SE7706428A patent/SE446336B/xx unknown
- 1977-06-02 NL NL7706064A patent/NL7706064A/xx not_active Application Discontinuation
-
1978
- 1978-06-01 ES ES470428A patent/ES470428A1/es not_active Expired
-
1979
- 1979-02-28 ES ES478156A patent/ES478156A1/es not_active Expired
- 1979-06-28 ES ES482010A patent/ES482010A1/es not_active Expired
-
1980
- 1980-03-25 ES ES489883A patent/ES8103057A1/es not_active Expired
-
1982
- 1982-05-19 SE SE8203161A patent/SE8203161L/sv not_active Application Discontinuation
-
1984
- 1984-02-07 CH CH576/84A patent/CH647511A5/de not_active IP Right Cessation
- 1984-02-07 CH CH57784A patent/CH646426A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPS52151168A (en) | 1977-12-15 |
CH647511A5 (en) | 1985-01-31 |
ES489883A0 (es) | 1981-02-16 |
FI71930C (fi) | 1987-03-09 |
FI71930B (fi) | 1986-11-28 |
NZ184281A (en) | 1980-04-28 |
ES459412A1 (es) | 1978-11-01 |
SE446336B (sv) | 1986-09-01 |
CA1176261A (en) | 1984-10-16 |
CH645631A5 (en) | 1984-10-15 |
HU183046B (en) | 1984-04-28 |
CH646426A5 (en) | 1984-11-30 |
FI771763A (fi) | 1977-12-04 |
DE2724948A1 (de) | 1977-12-15 |
FR2362839B1 (es) | 1980-02-01 |
SE7706428L (sv) | 1977-12-04 |
ES482010A1 (es) | 1980-08-16 |
JPS6222986B2 (es) | 1987-05-20 |
ES478156A1 (es) | 1979-11-01 |
NL7706064A (nl) | 1977-12-06 |
FR2362839A1 (fr) | 1978-03-24 |
SE8203161L (sv) | 1982-05-19 |
ES8103057A1 (es) | 1981-02-16 |
DK244577A (da) | 1977-12-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES478156A1 (es) | Un metodo de preparacion de compuestos heterociclicos derivados de hidantoina. | |
JPS5297950A (en) | Chalconeether derivatives | |
ES460040A1 (es) | Un procedimiento para preparar derivados de 4-hidroxifeni- lalcanolaminas. | |
ES460351A1 (es) | Procedimiento para la preparacion de 2-bromo-6 - fluor-n-2- imidazolidinilidenbenzamina. | |
ES384492A1 (es) | Procedimiento para la obtencion de derivados de acetil-gua-nidina. | |
ES473787A1 (es) | Un procedimiento para la preparacion de derivados de oxadia-zolopirimidina. | |
ES458176A1 (es) | Procedimiento para la preparacion de derivados de indazolil-(4)-oxi-propanolamina. | |
GB1471847A (en) | Dibenzofuran derivatives | |
ES472708A1 (es) | Procedimiento para la preparacion de derivados de bromhexina | |
JPS51130245A (en) | A display body | |
JPS5273878A (en) | Synthesis of 6-carboxyacetyl-3,4-dihydrocarbostyril | |
JPS52106844A (en) | 3-cyanomethylcyclopentanone derivatives | |
ES465346A1 (es) | Procedimiento para preparar imidazoles 4,5-disustituidos. | |
ES457096A1 (es) | Procedimiento de preparacion de la n-propargil-piperonilami-na. | |
ES471207A1 (es) | Metodo para la preparacion de nuevos derivados condensados de pirimidina | |
JPS5346968A (en) | Novel hexadecapeptides | |
FI772264A (es) | ||
ES8305333A1 (es) | "procedimiento para la preparacion de nuevas sulfiminas". | |
ES460297A1 (es) | Un compuesto. | |
JPS52118458A (en) | Novel methanoanthracene derivatives | |
ES482304A1 (es) | Procedimiento para la obtencion de nuevos derivados de mono y dio-oxoquinoxalinas. | |
JPS5321169A (en) | Novel lactone derivatives | |
JPS52116472A (en) | Baciferacins | |
ES457552A1 (es) | Procedimiento para la preparacion de aminoalcoxi-cicloalca- nos. | |
JPS5346954A (en) | Utendin derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980401 |