ES457096A1 - Procedimiento de preparacion de la n-propargil-piperonilami-na. - Google Patents

Procedimiento de preparacion de la n-propargil-piperonilami-na.

Info

Publication number
ES457096A1
ES457096A1 ES457096A ES457096A ES457096A1 ES 457096 A1 ES457096 A1 ES 457096A1 ES 457096 A ES457096 A ES 457096A ES 457096 A ES457096 A ES 457096A ES 457096 A1 ES457096 A1 ES 457096A1
Authority
ES
Spain
Prior art keywords
piperonylamine
derivatives
aggression
propargyl
fatigue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457096A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of ES457096A1 publication Critical patent/ES457096A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/52—Radicals substituted by halogen atoms or nitro radicals

Abstract

Procedimiento de preparación de la N-progargilpiperonilamina de fórmula: *** y de sus sales de adición, caracterizado porque se hace reaccionar la 3,4-metilendioxi-bencilamina con un halogenuro de propargilo de fórmula: Hal-CH2-C=CH Donde Hal representa I, Br, Cl, F; y porque si es necesario, se transforma la base así obtenida en sal de adición de ácido.
ES457096A 1976-03-23 1977-03-22 Procedimiento de preparacion de la n-propargil-piperonilami-na. Expired ES457096A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB11709/76A GB1531781A (en) 1976-03-23 1976-03-23 N-propargyl-piperonylamine and its preparation and use

Publications (1)

Publication Number Publication Date
ES457096A1 true ES457096A1 (es) 1978-03-01

Family

ID=9991251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES457096A Expired ES457096A1 (es) 1976-03-23 1977-03-22 Procedimiento de preparacion de la n-propargil-piperonilami-na.

Country Status (14)

Country Link
US (1) US4128656A (es)
JP (1) JPS6040432B2 (es)
BE (1) BE852742A (es)
CA (1) CA1091239A (es)
CH (1) CH602701A5 (es)
DE (1) DE2712432C2 (es)
DK (1) DK149955C (es)
ES (1) ES457096A1 (es)
FR (1) FR2345442A1 (es)
GB (1) GB1531781A (es)
IE (1) IE44654B1 (es)
LU (1) LU76987A1 (es)
NL (1) NL7703165A (es)
SE (1) SE431751B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725602A (en) * 1984-02-06 1988-02-16 Mcneilab, Inc. Acetylene amines and their use as vasodilators and antihypertensives
FR2569186B1 (fr) * 1984-08-20 1986-09-05 Lafon Labor Derives de 1-(n-(a-amino-a-methylacetyl)-aminophenyl)-2-amino-propanone, procede de preparation et utilisation en therapeutique
CN102977081B (zh) * 2012-10-22 2015-03-18 广西师范大学 胡椒乙胺缩吡啶-2-甲醛及其合成方法和应用
US20210330061A1 (en) * 2020-04-25 2021-10-28 Everyday Ingenuity LLC DBA BackPackJacks Attachable backpack apparatus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201470A (en) * 1965-08-17 Chsx c cech
US2578696A (en) * 1949-07-20 1951-12-18 Givaudan Corp N-(2-chloroethyl)-n-piperonyl amines
US3532749A (en) * 1965-05-11 1970-10-06 Aldrich Chem Co Inc N'-propargyl-n**2-cyclopropyl-ethylenediamines and the salts thereof
US3471522A (en) * 1967-09-29 1969-10-07 Aldrich Chem Co Inc N-cyclopropyl-n'-furfuryl-n'-methyl ethylene diamines
US3523954A (en) * 1968-03-07 1970-08-11 Boehringer Sohn Ingelheim Novel alpha-amino-substituted (3,4-methylenedioxy - phenyl) - alkanones and salts thereof

Also Published As

Publication number Publication date
JPS6040432B2 (ja) 1985-09-11
DK149955C (da) 1987-06-29
IE44654B1 (en) 1982-02-10
GB1531781A (en) 1978-11-08
NL7703165A (nl) 1977-09-27
LU76987A1 (es) 1977-07-18
CH602701A5 (es) 1978-07-31
FR2345442A1 (fr) 1977-10-21
SE431751B (sv) 1984-02-27
US4128656A (en) 1978-12-05
SE7703261L (sv) 1977-09-24
DK126577A (da) 1977-09-24
DE2712432A1 (de) 1977-10-06
JPS52116468A (en) 1977-09-29
BE852742A (fr) 1977-09-22
FR2345442B1 (es) 1980-06-06
IE44654L (en) 1977-09-23
DE2712432C2 (de) 1986-07-24
CA1091239A (en) 1980-12-09
DK149955B (da) 1986-11-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202