SE446336B - Sett att framstella en 1,5-disubstituerad hydantoin, som har inhiberande effekt pa blodplettsaggregation - Google Patents

Sett att framstella en 1,5-disubstituerad hydantoin, som har inhiberande effekt pa blodplettsaggregation

Info

Publication number
SE446336B
SE446336B SE7706428A SE7706428A SE446336B SE 446336 B SE446336 B SE 446336B SE 7706428 A SE7706428 A SE 7706428A SE 7706428 A SE7706428 A SE 7706428A SE 446336 B SE446336 B SE 446336B
Authority
SE
Sweden
Prior art keywords
make
blood spot
inhibitive effect
disubstituted hydantoin
spot segregation
Prior art date
Application number
SE7706428A
Other languages
English (en)
Swedish (sv)
Other versions
SE7706428L (sv
Inventor
A G Caldwell
N Whittaker
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SE7706428L publication Critical patent/SE7706428L/xx
Publication of SE446336B publication Critical patent/SE446336B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7706428A 1976-06-03 1977-06-02 Sett att framstella en 1,5-disubstituerad hydantoin, som har inhiberande effekt pa blodplettsaggregation SE446336B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2287776 1976-06-03
GB5034076 1976-12-02
GB1214577 1977-03-23

Publications (2)

Publication Number Publication Date
SE7706428L SE7706428L (sv) 1977-12-04
SE446336B true SE446336B (sv) 1986-09-01

Family

ID=27256793

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7706428A SE446336B (sv) 1976-06-03 1977-06-02 Sett att framstella en 1,5-disubstituerad hydantoin, som har inhiberande effekt pa blodplettsaggregation
SE8203161A SE8203161L (sv) 1976-06-03 1982-05-19 Sett att framstella 1,5-disubstituerade hydantoinanaloger

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8203161A SE8203161L (sv) 1976-06-03 1982-05-19 Sett att framstella 1,5-disubstituerade hydantoinanaloger

Country Status (12)

Country Link
JP (1) JPS52151168A (da)
CA (1) CA1176261A (da)
CH (3) CH645631A5 (da)
DE (1) DE2724948A1 (da)
DK (1) DK244577A (da)
ES (5) ES459412A1 (da)
FI (1) FI71930C (da)
FR (1) FR2362839A1 (da)
HU (1) HU183046B (da)
NL (1) NL7706064A (da)
NZ (1) NZ184281A (da)
SE (2) SE446336B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
JPS5463083A (en) * 1977-09-05 1979-05-21 Wellcome Found Organism active nitrogen compound
ZA786739B (en) * 1977-12-01 1980-07-30 Wellcome Found Hydantoin derivatives and salts thereof,their syntheses,and intermediates,and pharmaceutical formulations
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
US4294972A (en) * 1978-06-15 1981-10-13 Beecham Group Limited 1,2-Disubstituted oxo triazolidine
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
IL59065A0 (en) * 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
GB2050371A (en) * 1979-05-09 1981-01-07 Wellcome Found Optically active hydantoin derivatives and pharmaceutical formulations containing them
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JP3022878U (ja) * 1995-08-18 1996-04-02 有限会社春江加工 ミニディスク用ケース
KR20050044606A (ko) * 2001-11-30 2005-05-12 일라이 릴리 앤드 캄파니 퍼옥시솜 증식제에 의해 활성화된 수용체 아고니스트
CA2528179C (en) * 2003-06-06 2013-10-22 Allergan, Inc. Piperidinyl prostaglandin e analogs
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
JPS52151168A (en) 1977-12-15
CH647511A5 (en) 1985-01-31
ES489883A0 (es) 1981-02-16
FI71930C (fi) 1987-03-09
FI71930B (fi) 1986-11-28
NZ184281A (en) 1980-04-28
ES459412A1 (es) 1978-11-01
CA1176261A (en) 1984-10-16
CH645631A5 (en) 1984-10-15
HU183046B (en) 1984-04-28
CH646426A5 (en) 1984-11-30
FI771763A (fi) 1977-12-04
DE2724948A1 (de) 1977-12-15
FR2362839B1 (da) 1980-02-01
ES470428A1 (es) 1979-09-01
SE7706428L (sv) 1977-12-04
ES482010A1 (es) 1980-08-16
JPS6222986B2 (da) 1987-05-20
ES478156A1 (es) 1979-11-01
NL7706064A (nl) 1977-12-06
FR2362839A1 (fr) 1978-03-24
SE8203161L (sv) 1982-05-19
ES8103057A1 (es) 1981-02-16
DK244577A (da) 1977-12-04

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