CH630625A5 - Process for the preparation of antihypertensive 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl]quinazoline - Google Patents

Process for the preparation of antihypertensive 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl]quinazoline Download PDF

Info

Publication number
CH630625A5
CH630625A5 CH1438177A CH1438177A CH630625A5 CH 630625 A5 CH630625 A5 CH 630625A5 CH 1438177 A CH1438177 A CH 1438177A CH 1438177 A CH1438177 A CH 1438177A CH 630625 A5 CH630625 A5 CH 630625A5
Authority
CH
Switzerland
Prior art keywords
dimethoxy
furoyl
piperazinyl
formula
quinazoline
Prior art date
Application number
CH1438177A
Other languages
German (de)
English (en)
Inventor
Erkki Juhani Honkanen
Aino Kyllikki Pippuri
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of CH630625A5 publication Critical patent/CH630625A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1438177A 1976-12-15 1977-11-24 Process for the preparation of antihypertensive 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl]quinazoline CH630625A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI763613A FI58125C (fi) 1976-12-15 1976-12-15 Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande vekan

Publications (1)

Publication Number Publication Date
CH630625A5 true CH630625A5 (en) 1982-06-30

Family

ID=8510503

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1438177A CH630625A5 (en) 1976-12-15 1977-11-24 Process for the preparation of antihypertensive 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl]quinazoline

Country Status (17)

Country Link
JP (1) JPS5387377A (no)
AT (1) AT358048B (no)
BE (1) BE861821A (no)
CA (1) CA1092117A (no)
CH (1) CH630625A5 (no)
CS (1) CS195347B2 (no)
DD (1) DD133671A1 (no)
DE (1) DE2755637A1 (no)
DK (1) DK144972C (no)
FI (1) FI58125C (no)
HU (1) HU174047B (no)
NL (1) NL7713702A (no)
NO (1) NO147244C (no)
PL (1) PL106031B1 (no)
SE (1) SE435284B (no)
SU (1) SU753360A3 (no)
ZA (1) ZA777223B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
PL3290414T3 (pl) * 2012-05-23 2020-01-31 Nerviano Medical Sciences S.R.L. Sposób otrzymywania n-[5-(3,5-difluorobenzylo)-1h-indazol-3-ilo]-4-(4-metylopiperazyn-1-ylo)-2-(tetrahydropiran-4-yloamino)benzamidu

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
CA1092117A (en) 1980-12-23
AT358048B (de) 1980-08-11
NL7713702A (nl) 1978-06-19
HU174047B (hu) 1979-10-28
NO147244B (no) 1982-11-22
FI58125C (fi) 1985-01-02
DE2755637C2 (no) 1987-09-24
DK144972C (da) 1988-08-29
NO147244C (no) 1984-10-09
ZA777223B (en) 1978-09-27
DK144972B (da) 1982-07-19
FI58125B (fi) 1980-08-29
ATA867277A (de) 1980-01-15
JPS5387377A (en) 1978-08-01
DD133671A1 (de) 1979-01-17
NO774262L (no) 1978-06-16
FI763613A (fi) 1978-06-16
SU753360A3 (ru) 1980-07-30
DK558277A (da) 1978-06-16
PL106031B1 (pl) 1979-11-30
DE2755637A1 (de) 1978-06-22
CS195347B2 (en) 1980-01-31
JPS6225147B2 (no) 1987-06-01
SE7713376L (sv) 1978-06-16
SE435284B (sv) 1984-09-17
PL202899A1 (pl) 1978-08-28
BE861821A (fr) 1978-03-31

Similar Documents

Publication Publication Date Title
DE69815126T2 (de) Pyrimidinderivate und verfahren zu deren herstellung
DE2451480C2 (no)
DE1620035A1 (de) 3-Amino-5-X-6-halogenpyrazinonitrile und Verfahren zu deren Herstellung
DE2457911A1 (de) Verfahren zur herstellung von chinazolinen
CH645100A5 (de) Substituierte 3-aryl-pyrazole und 5-aryl-isoxazole und verfahren zu ihrer herstellung.
DE2205745A1 (de) Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung
DE2614189A1 (de) Therapeutisch wirksame ureido- und semicarbazido-derivate des tiazols und verfahren zu ihrer herstellung
EP0687256B1 (de) Hydroxymethylfurazancarbonsäurederivate und ihre verwendung in der behandlung von kardiovaskulären erkrankungen
CH630625A5 (en) Process for the preparation of antihypertensive 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl]quinazoline
DE2740331C3 (de) 2-(-4-Cyano-piperanzino)-4-amino-6,7-dimethoxy-chinazolin und dessen Verwendung zur Herstellung von 2-[4-(2-Furoyl)piperazin-o]-4-amino-6,7-dimethoxychinazolin
CH638517A5 (en) Process for preparing substituted aminoquinazoline derivatives
EP0146642B1 (de) Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze
EP0582288B1 (de) Verfahren zur Herstellung von 2-Halogen-4,6-dialkoxypyrimidinen
CH393347A (de) Verfahren zur Herstellung von Derivaten des Pyrimido (5,4-d) pyrimidins
DE2233481A1 (de) Verfahren zur herstellung von tetramisol
CH630624A5 (en) Processes for preparing 3,4-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinylthiocarbamido)benzo nitrile.
DE3617793C2 (de) Verfahren zur Herstellung von Cyansubstituierten Enolethern
EP0276721A1 (de) 2-Cyan-2-oximino-acetamide
CH639959A5 (de) 2,4-diamino-5-thiobenzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DD150057A5 (de) Verfahren zur herstellung von 2-aminopyrazinen
US4929728A (en) Process for preparing 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone
AT256863B (de) Verfahren zur Herstellung neuer basischer Derivate des Dihydro-1, 3-benzoxazin-2, 4-dions
DE3332148A1 (de) Thiazolderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
DE2546667A1 (de) Neue 2,4-diamino-5-benzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE1620179A1 (de) Verfahren zur Herstellung neuer basischer Derivate des Benzoxazins

Legal Events

Date Code Title Description
PL Patent ceased