ZA777223B - Method for the production of 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect - Google Patents

Method for the production of 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect

Info

Publication number
ZA777223B
ZA777223B ZA00777223A ZA777223A ZA777223B ZA 777223 B ZA777223 B ZA 777223B ZA 00777223 A ZA00777223 A ZA 00777223A ZA 777223 A ZA777223 A ZA 777223A ZA 777223 B ZA777223 B ZA 777223B
Authority
ZA
South Africa
Prior art keywords
furoyl
quinazoline
piperazinyl
dimethoxy
amino
Prior art date
Application number
ZA00777223A
Inventor
A Pippuri
E Honkanen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of ZA777223B publication Critical patent/ZA777223B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00777223A 1976-12-15 1977-12-05 Method for the production of 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect ZA777223B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI763613A FI58125C (en) 1976-12-15 1976-12-15 PROCEDURE FOR FRAMSTATING AV 6,7-DIMETOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) QUINAZOLINE WITH BLODTRYCKSSAENKANDE VEKAN

Publications (1)

Publication Number Publication Date
ZA777223B true ZA777223B (en) 1978-09-27

Family

ID=8510503

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00777223A ZA777223B (en) 1976-12-15 1977-12-05 Method for the production of 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect

Country Status (17)

Country Link
JP (1) JPS5387377A (en)
AT (1) AT358048B (en)
BE (1) BE861821A (en)
CA (1) CA1092117A (en)
CH (1) CH630625A5 (en)
CS (1) CS195347B2 (en)
DD (1) DD133671A1 (en)
DE (1) DE2755637A1 (en)
DK (1) DK144972C (en)
FI (1) FI58125C (en)
HU (1) HU174047B (en)
NL (1) NL7713702A (en)
NO (1) NO147244C (en)
PL (1) PL106031B1 (en)
SE (1) SE435284B (en)
SU (1) SU753360A3 (en)
ZA (1) ZA777223B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI67699C (en) * 1979-01-31 1985-05-10 Orion Yhtymae Oy PROCEDURE FOR THE FRAMSTATION OF AV 6,7-DIMETOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) QUINAZOLINE HYDROCHLORIDE WITH BLODTRYCKSSAENKANDE VERKAN
EP2855460B1 (en) * 2012-05-23 2017-11-08 Nerviano Medical Sciences S.r.l. Process for the preparation of n-[5-(3,5-difluoro-benzyl)-1h-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
SE435284B (en) 1984-09-17
SU753360A3 (en) 1980-07-30
FI58125C (en) 1985-01-02
HU174047B (en) 1979-10-28
NO147244C (en) 1984-10-09
AT358048B (en) 1980-08-11
JPS5387377A (en) 1978-08-01
DK144972C (en) 1988-08-29
NL7713702A (en) 1978-06-19
NO774262L (en) 1978-06-16
SE7713376L (en) 1978-06-16
PL202899A1 (en) 1978-08-28
FI763613A (en) 1978-06-16
CH630625A5 (en) 1982-06-30
DK558277A (en) 1978-06-16
CS195347B2 (en) 1980-01-31
DD133671A1 (en) 1979-01-17
JPS6225147B2 (en) 1987-06-01
NO147244B (en) 1982-11-22
CA1092117A (en) 1980-12-23
PL106031B1 (en) 1979-11-30
BE861821A (en) 1978-03-31
DE2755637C2 (en) 1987-09-24
ATA867277A (en) 1980-01-15
DE2755637A1 (en) 1978-06-22
FI58125B (en) 1980-08-29
DK144972B (en) 1982-07-19

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