CH626632A5 - Process for the preparation of halopregnadienes - Google Patents

Process for the preparation of halopregnadienes Download PDF

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Publication number
CH626632A5
CH626632A5 CH1615075A CH1615075A CH626632A5 CH 626632 A5 CH626632 A5 CH 626632A5 CH 1615075 A CH1615075 A CH 1615075A CH 1615075 A CH1615075 A CH 1615075A CH 626632 A5 CH626632 A5 CH 626632A5
Authority
CH
Switzerland
Prior art keywords
acid
dichloro
group
paramethasone
compounds
Prior art date
Application number
CH1615075A
Other languages
German (de)
English (en)
Inventor
Georg Dr Anner
Charles Dr Meystre
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1615075A priority Critical patent/CH626632A5/de
Priority to DE19762655802 priority patent/DE2655802A1/de
Priority to NL7613711A priority patent/NL7613711A/xx
Priority to FR7637093A priority patent/FR2358152A1/fr
Priority to IE2699/76A priority patent/IE44512B1/en
Priority to GB51695/76A priority patent/GB1563595A/en
Priority to CA267,597A priority patent/CA1078824A/en
Priority to AU20471/76A priority patent/AU510864B2/en
Priority to ES454119A priority patent/ES454119A1/es
Priority to HU76CI1703A priority patent/HU176936B/hu
Priority to SE7613919A priority patent/SE7613919L/xx
Priority to BE173137A priority patent/BE849267A/xx
Priority to DD7600196260A priority patent/DD128682A5/xx
Priority to NZ182865A priority patent/NZ182865A/xx
Priority to AT914176A priority patent/AT353432B/de
Priority to ZA767381A priority patent/ZA767381B/xx
Priority to DK557576AA priority patent/DK142326B/da
Priority to IL51085A priority patent/IL51085A/xx
Priority to JP51149325A priority patent/JPS5273852A/ja
Priority to ES465551A priority patent/ES465551A1/es
Priority to AT0491279A priority patent/AT368521B/de
Priority to AT0491379A priority patent/AT368522B/de
Priority to CH799480A priority patent/CH626094A5/de
Publication of CH626632A5 publication Critical patent/CH626632A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
CH1615075A 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes CH626632A5 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
CH1615075A CH626632A5 (en) 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes
DE19762655802 DE2655802A1 (de) 1975-12-12 1976-12-09 Neue halogenpregnadiene und verfahren zu ihrer herstellung
NL7613711A NL7613711A (nl) 1975-12-12 1976-12-09 Werkwijze voor de bereiding van nieuwe halogeen- pregnadienen.
FR7637093A FR2358152A1 (fr) 1975-12-12 1976-12-09 Nouveaux pregnadienes halogenes et leur procede de preparation
IE2699/76A IE44512B1 (en) 1975-12-12 1976-12-10 Novel halogenopregnadienes and process for the manufacture thereof
GB51695/76A GB1563595A (en) 1975-12-12 1976-12-10 Halogenoprepnadienes and process for the manufacture thereof
CA267,597A CA1078824A (en) 1975-12-12 1976-12-10 Halogenopregnadienes and process for the manufacture thereof
AU20471/76A AU510864B2 (en) 1975-12-12 1976-12-10 Halopregnadienes
ES454119A ES454119A1 (es) 1975-12-12 1976-12-10 Procedimiento para la obtencion de halogenopregnadienos.
HU76CI1703A HU176936B (hu) 1975-12-12 1976-12-10 Sposob poluchenija novykh galogenozamehhjonnykh pregnadienov
SE7613919A SE7613919L (sv) 1975-12-12 1976-12-10 Nya halogenpregnadioner och forfarande for framstellning derav
BE173137A BE849267A (fr) 1975-12-12 1976-12-10 Nouveaux pregnadienes halogenes et leur procede de preparation
DD7600196260A DD128682A5 (de) 1975-12-12 1976-12-10 Verfahren zur herstellung neuer halogenpregnadiene
NZ182865A NZ182865A (en) 1975-12-12 1976-12-10 2.9 -dichloro-6 -fluoro-16 -methyl-11 ,17 , 21-trihydroxy-pregna-1,4-diene-3,20-diones
AT914176A AT353432B (de) 1975-12-12 1976-12-10 Verfahren zur herstellung von neuen halogen- pregnadienen
ZA767381A ZA767381B (en) 1975-12-12 1976-12-10 Novel halogenopregnadienes and process for the manufacture thereof
DK557576AA DK142326B (da) 1975-12-12 1976-12-10 Analogifremgangsmåde til fremstilling af 2,9alfa-dichlor-6alfa-fluor-16alfa-methyl-11beta, 17alfa,21-trihydroxy-pregna-1,4-dien-3,20-dionforbindelser eller salte af estere af polybasiske syrer.
IL51085A IL51085A (en) 1975-12-12 1976-12-10 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them
JP51149325A JPS5273852A (en) 1975-12-12 1976-12-11 Production of 2*9 alphaa dichlorooparamethazone compound and pharmaceutical composition containing the same
ES465551A ES465551A1 (es) 1975-12-12 1977-12-29 Procedimiento para la obtencion de halogenopregnadienos.
AT0491279A AT368521B (de) 1975-12-12 1979-07-16 Verfahren zur herstellung von neuen 2,9 alpha-
AT0491379A AT368522B (de) 1975-12-12 1979-07-16 Verfahren zur herstellung von neuen 2,9alpha-
CH799480A CH626094A5 (en) 1975-12-12 1980-10-27 Process for the preparation of halopregnadienes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1615075A CH626632A5 (en) 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes

Publications (1)

Publication Number Publication Date
CH626632A5 true CH626632A5 (en) 1981-11-30

Family

ID=4414834

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1615075A CH626632A5 (en) 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes
CH799480A CH626094A5 (en) 1975-12-12 1980-10-27 Process for the preparation of halopregnadienes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH799480A CH626094A5 (en) 1975-12-12 1980-10-27 Process for the preparation of halopregnadienes

Country Status (19)

Country Link
JP (1) JPS5273852A (ja)
AT (1) AT353432B (ja)
AU (1) AU510864B2 (ja)
BE (1) BE849267A (ja)
CA (1) CA1078824A (ja)
CH (2) CH626632A5 (ja)
DD (1) DD128682A5 (ja)
DE (1) DE2655802A1 (ja)
DK (1) DK142326B (ja)
ES (2) ES454119A1 (ja)
FR (1) FR2358152A1 (ja)
GB (1) GB1563595A (ja)
HU (1) HU176936B (ja)
IE (1) IE44512B1 (ja)
IL (1) IL51085A (ja)
NL (1) NL7613711A (ja)
NZ (1) NZ182865A (ja)
SE (1) SE7613919L (ja)
ZA (1) ZA767381B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid

Also Published As

Publication number Publication date
GB1563595A (en) 1980-03-26
IE44512L (en) 1977-06-12
ZA767381B (en) 1977-11-30
AU510864B2 (en) 1980-07-17
AT353432B (de) 1979-11-12
FR2358152A1 (fr) 1978-02-10
ATA914176A (de) 1979-04-15
IL51085A0 (en) 1977-02-28
BE849267A (fr) 1977-06-10
HU176936B (hu) 1981-06-28
NL7613711A (nl) 1977-06-14
ES454119A1 (es) 1978-03-01
FR2358152B1 (ja) 1982-10-22
DK142326C (ja) 1981-03-09
IE44512B1 (en) 1981-12-30
DK142326B (da) 1980-10-13
CA1078824A (en) 1980-06-03
SE7613919L (sv) 1977-06-13
DK557576A (ja) 1977-06-13
ES465551A1 (es) 1978-09-16
AU2047176A (en) 1978-06-15
DE2655802A1 (de) 1977-06-16
JPS5273852A (en) 1977-06-21
CH626094A5 (en) 1981-10-30
NZ182865A (en) 1979-06-08
DD128682A5 (de) 1977-12-07
IL51085A (en) 1980-09-16

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PL Patent ceased