DK142326B - Analogifremgangsmåde til fremstilling af 2,9alfa-dichlor-6alfa-fluor-16alfa-methyl-11beta, 17alfa,21-trihydroxy-pregna-1,4-dien-3,20-dionforbindelser eller salte af estere af polybasiske syrer. - Google Patents

Analogifremgangsmåde til fremstilling af 2,9alfa-dichlor-6alfa-fluor-16alfa-methyl-11beta, 17alfa,21-trihydroxy-pregna-1,4-dien-3,20-dionforbindelser eller salte af estere af polybasiske syrer. Download PDF

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Publication number
DK142326B
DK142326B DK557576AA DK557576A DK142326B DK 142326 B DK142326 B DK 142326B DK 557576A A DK557576A A DK 557576AA DK 557576 A DK557576 A DK 557576A DK 142326 B DK142326 B DK 142326B
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DK
Denmark
Prior art keywords
acid
dichloro
fluoro
methyl
esters
Prior art date
Application number
DK557576AA
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Danish (da)
English (en)
Other versions
DK142326C (ja
DK557576A (ja
Inventor
Georg Anner
Charles Meystre
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK557576A publication Critical patent/DK557576A/da
Publication of DK142326B publication Critical patent/DK142326B/da
Application granted granted Critical
Publication of DK142326C publication Critical patent/DK142326C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
DK557576AA 1975-12-12 1976-12-10 Analogifremgangsmåde til fremstilling af 2,9alfa-dichlor-6alfa-fluor-16alfa-methyl-11beta, 17alfa,21-trihydroxy-pregna-1,4-dien-3,20-dionforbindelser eller salte af estere af polybasiske syrer. DK142326B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1615075A CH626632A5 (en) 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes
CH1615075 1975-12-12

Publications (3)

Publication Number Publication Date
DK557576A DK557576A (ja) 1977-06-13
DK142326B true DK142326B (da) 1980-10-13
DK142326C DK142326C (ja) 1981-03-09

Family

ID=4414834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK557576AA DK142326B (da) 1975-12-12 1976-12-10 Analogifremgangsmåde til fremstilling af 2,9alfa-dichlor-6alfa-fluor-16alfa-methyl-11beta, 17alfa,21-trihydroxy-pregna-1,4-dien-3,20-dionforbindelser eller salte af estere af polybasiske syrer.

Country Status (19)

Country Link
JP (1) JPS5273852A (ja)
AT (1) AT353432B (ja)
AU (1) AU510864B2 (ja)
BE (1) BE849267A (ja)
CA (1) CA1078824A (ja)
CH (2) CH626632A5 (ja)
DD (1) DD128682A5 (ja)
DE (1) DE2655802A1 (ja)
DK (1) DK142326B (ja)
ES (2) ES454119A1 (ja)
FR (1) FR2358152A1 (ja)
GB (1) GB1563595A (ja)
HU (1) HU176936B (ja)
IE (1) IE44512B1 (ja)
IL (1) IL51085A (ja)
NL (1) NL7613711A (ja)
NZ (1) NZ182865A (ja)
SE (1) SE7613919L (ja)
ZA (1) ZA767381B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid

Also Published As

Publication number Publication date
GB1563595A (en) 1980-03-26
IE44512L (en) 1977-06-12
ZA767381B (en) 1977-11-30
AU510864B2 (en) 1980-07-17
AT353432B (de) 1979-11-12
FR2358152A1 (fr) 1978-02-10
ATA914176A (de) 1979-04-15
IL51085A0 (en) 1977-02-28
BE849267A (fr) 1977-06-10
HU176936B (hu) 1981-06-28
NL7613711A (nl) 1977-06-14
ES454119A1 (es) 1978-03-01
FR2358152B1 (ja) 1982-10-22
DK142326C (ja) 1981-03-09
IE44512B1 (en) 1981-12-30
CA1078824A (en) 1980-06-03
SE7613919L (sv) 1977-06-13
DK557576A (ja) 1977-06-13
ES465551A1 (es) 1978-09-16
AU2047176A (en) 1978-06-15
DE2655802A1 (de) 1977-06-16
JPS5273852A (en) 1977-06-21
CH626632A5 (en) 1981-11-30
CH626094A5 (en) 1981-10-30
NZ182865A (en) 1979-06-08
DD128682A5 (de) 1977-12-07
IL51085A (en) 1980-09-16

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