CH615934A5 - - Google Patents

Download PDF

Info

Publication number
CH615934A5
CH615934A5 CH24473A CH24473A CH615934A5 CH 615934 A5 CH615934 A5 CH 615934A5 CH 24473 A CH24473 A CH 24473A CH 24473 A CH24473 A CH 24473A CH 615934 A5 CH615934 A5 CH 615934A5
Authority
CH
Switzerland
Prior art keywords
dione
hydroxy
trimethyl
compound
pregnen
Prior art date
Application number
CH24473A
Other languages
German (de)
English (en)
Inventor
Gilbert Frederick Woods
James Cairns
George Mcgarry
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of CH615934A5 publication Critical patent/CH615934A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH24473A 1972-01-12 1973-01-09 CH615934A5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB153472A GB1416427A (en) 1972-01-12 1972-01-12 Alkylated pregnanes and process for obtaining same

Publications (1)

Publication Number Publication Date
CH615934A5 true CH615934A5 (es) 1980-02-29

Family

ID=9723658

Family Applications (1)

Application Number Title Priority Date Filing Date
CH24473A CH615934A5 (es) 1972-01-12 1973-01-09

Country Status (17)

Country Link
US (1) US3862194A (es)
JP (1) JPS5614678B2 (es)
AT (1) AT367068B (es)
BE (1) BE793958A (es)
CA (1) CA1022158A (es)
CH (1) CH615934A5 (es)
DE (1) DE2301317C2 (es)
DK (1) DK139031B (es)
FI (1) FI52587C (es)
FR (1) FR2168006B1 (es)
GB (1) GB1416427A (es)
HU (1) HU167205B (es)
IE (1) IE37048B1 (es)
IL (1) IL41160A (es)
NL (2) NL179287C (es)
PH (1) PH9719A (es)
SE (1) SE411213B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947478A (en) * 1972-01-12 1976-03-30 Akzona Incorporated Alkylated 3,20-diketo-Δ4 -steroids of the pregnane series
GB1436324A (en) * 1972-05-12 1976-05-19 Glaxo Lab Ltd Anaesthetic 3alpha-hydroxy pregnanes
US4031075A (en) * 1973-07-11 1977-06-21 Akzona Incorporated Alkylated pregnanes and process for obtaining same
GB1478968A (en) * 1973-07-11 1977-07-06 Akzo Nv Alkylated pregnanes
JPS5264666A (en) * 1975-11-25 1977-05-28 Sharp Kk Bothhside circuit substrate
DE3064460D1 (en) * 1979-01-24 1983-09-08 Akzo Nv Novel alkylated pregnanes, processes for their preparation and pharmaceutical compositions containing same
JPS58194A (ja) * 1981-06-25 1983-01-05 北陸電気工業株式会社 Cu粉末導電塗料を用いた印刷抵抗回路基板の製造方法
US4686214A (en) * 1985-10-30 1987-08-11 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
WO1991014700A2 (en) * 1990-03-27 1991-10-03 Schering Corporation PROCESS FOR 9α-HYDROXY STEROID DEHYDRATION
WO1997022616A1 (en) * 1995-12-20 1997-06-26 Schering Corporation PROCESS FOR PREPARATION OF 9,11β-EPOXIDE STEROIDS
EP0882062A1 (en) * 1996-10-25 1998-12-09 Alcon Laboratories, Inc. Method of preparing 21-alkylated pregna-1,4,16-trien-3,20-diones
US6040468A (en) * 1996-10-25 2000-03-21 Alcon Laboratories, Inc. Method of preparing 16α, 17α-dialkylated steroids
CA2290775A1 (en) * 1997-06-04 1998-12-10 Akzo Nobel Nv Use of anti-inflammatory steroids for the treatment of chronic inflammatory intestinal diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3064017A (en) * 1962-11-13 Preparation viii
US3047594A (en) * 1960-05-11 1962-07-31 Pfizer & Co C Preparation of 21-methyl steroids and intermediates
US3114750A (en) * 1960-11-07 1963-12-17 British Drug Houses Ltd 3-enol ethers of 6-formyl-3-oxo-delta4-steroids and process for their preparation
US3166551A (en) * 1962-01-02 1965-01-19 British Drug Houses Ltd Process for the preparation of 3-oxo-delta4-6-methyl steroids
DE1167829B (de) * 1962-08-03 1964-04-16 Schering Ag Verfahren zur Herstellung von 21-Methyl-í¸-pregnen-11ª‰, 17ª‡-diol-3, 20-dion
US3594407A (en) * 1969-04-03 1971-07-20 American Home Prod 13,17-dialkyl-19-norpregn-4-ene,3,20-diones

Also Published As

Publication number Publication date
NL7300313A (es) 1973-07-16
FI52587B (es) 1977-06-30
AT367068B (de) 1982-05-25
CA1022158A (en) 1977-12-06
SE411213B (sv) 1979-12-10
FR2168006A1 (es) 1973-08-24
FI52587C (fi) 1977-10-10
DK139031C (es) 1979-05-14
GB1416427A (en) 1975-12-03
IE37048B1 (en) 1977-04-27
IE37048L (en) 1973-07-12
ATA28373A (de) 1981-10-15
IL41160A0 (en) 1973-02-28
NL179287C (nl) 1986-08-18
PH9719A (en) 1976-02-27
JPS504060A (es) 1975-01-16
US3862194A (en) 1975-01-21
DK139031B (da) 1978-12-04
JPS5614678B2 (es) 1981-04-06
HU167205B (es) 1975-09-27
DE2301317A1 (de) 1973-07-26
NL930031I1 (nl) 1993-07-01
IL41160A (en) 1977-04-29
FR2168006B1 (es) 1976-09-03
BE793958A (fr) 1973-07-12
DE2301317C2 (de) 1983-11-03
NL179287B (nl) 1986-03-17

Similar Documents

Publication Publication Date Title
US3947478A (en) Alkylated 3,20-diketo-Δ4 -steroids of the pregnane series
CH615934A5 (es)
CH533094A (de) Verfahren zur Herstellung neuer Steroide
CH561739A5 (en) 4-Hydroxy-2-butenoic acid lactone steroid derivs - cardiotonic, anti-inflammatory, hypocholesterolaemic, mineralocorticoid agents
DE1668784A1 (de) Verfahren zur Oxydation primaerer und sekundaerer Alkohole
DE1468035A1 (de) Verfahren zur Herstellung von 19-Alkylsteroiden
CH645388A5 (de) Verfahren zur acylierung von tertiaeren sterisch gehinderten hydroxylgruppen von steroiden.
DE1172673B (de) Verfahren zur Herstellung von therapeutisch wirksamen Steroidverbindungen
DE1793618C3 (de) 07.03.63 USA 263441 Verfahren zur Herstellung von 3-Hydroxy-1,5-bisdehydrosteroiden der Androstanreihe
US2684376A (en) Process for the simultaneous oxidation and halogenation of steroids and compounds obtained thereby
DE2064859C3 (de) Neue 6 a -Fluor-16 a , 18dimethyl-l,4-pregnadien-3,20-dion Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2433178A1 (de) In 21-stellung alkylierte steroide der pregnanreihe
DE1643010A1 (de) Verfahren zur Herstellung von 17alpha-Alkinyl-17ss-alkanoyloxy-Steroiden der Andostran- und Oestranreihe
DE1793270A1 (de) 16alpha,17alpha-Methylensteroidverbindungen und Verfahren zu ihrer Herstellung
DE1468988B1 (de) 17alpha-Chloraethinyl-13beta-aethyl-4- oder -5(10)-gonen-3-ketone
DE1593209C3 (de) Verfahren zur 17 alpha-Alkylierung von 20-Ketosteroiden der Pregnanreihe und 17alpha-Alkylsteroide der Pregnanreihe
DE1493108C (de) Steroidverbindungen
AT257060B (de) Verfahren zur Herstellung von neuen 3-Enoläthern der 6-Methyl-3-oxo-Δ<4>-steroide der Androstan-, 19-Norandrostan-, Pregnan- und 19-Norpregnanreihe
DE1493163C3 (de) nalpha-Äthinyl-ie-methyl-Delta hoch 4-östren-3 beta-17 betadiole, Verfahren zu deren Herstellung sowie diese enthaltende Mittel
DE1468988C (de) nalpha-Chloräthinyl-lSbeta-äthyl-4-oder-5( 10)- gonen-3 -ketone.'
DE1793749C3 (de) Verfahren zur Herstellung von 1,4-Diensteroiden
AT363200B (de) Verfahren zur herstellung von neuen 9alpha, 21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-
DE1568766A1 (de) Verfahren zur Herstellung von Steroiden der Pregnanreihe
AT220764B (de) Verfahren zur Herstellung von neuen 3-Oxo-Δ<1,4>-6-methyl- und 3-Oxo-Δ<1,4,6>-6-methylsteroiden
AT228410B (de) Verfahren zur Herstellung neuer 6-Methyl-3-oxo-4, 6-dien-steroide

Legal Events

Date Code Title Description
PL Patent ceased