AT367068B - Verfahren zur herstellung neuer alkylierter 3,20-diketo-delta 4-steroide der pregnanreihe - Google Patents

Verfahren zur herstellung neuer alkylierter 3,20-diketo-delta 4-steroide der pregnanreihe

Info

Publication number
AT367068B
AT367068B AT0028373A AT28373A AT367068B AT 367068 B AT367068 B AT 367068B AT 0028373 A AT0028373 A AT 0028373A AT 28373 A AT28373 A AT 28373A AT 367068 B AT367068 B AT 367068B
Authority
AT
Austria
Prior art keywords
diketo
steroids
delta
producing new
pregnane series
Prior art date
Application number
AT0028373A
Other languages
English (en)
Other versions
ATA28373A (de
Inventor
Gilbert Frederik Woods
James Cairns
George Mcgarry
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ATA28373A publication Critical patent/ATA28373A/de
Application granted granted Critical
Publication of AT367068B publication Critical patent/AT367068B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0028373A 1972-01-12 1973-01-12 Verfahren zur herstellung neuer alkylierter 3,20-diketo-delta 4-steroide der pregnanreihe AT367068B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB153472A GB1416427A (en) 1972-01-12 1972-01-12 Alkylated pregnanes and process for obtaining same

Publications (2)

Publication Number Publication Date
ATA28373A ATA28373A (de) 1981-10-15
AT367068B true AT367068B (de) 1982-05-25

Family

ID=9723658

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0028373A AT367068B (de) 1972-01-12 1973-01-12 Verfahren zur herstellung neuer alkylierter 3,20-diketo-delta 4-steroide der pregnanreihe

Country Status (17)

Country Link
US (1) US3862194A (de)
JP (1) JPS5614678B2 (de)
AT (1) AT367068B (de)
BE (1) BE793958A (de)
CA (1) CA1022158A (de)
CH (1) CH615934A5 (de)
DE (1) DE2301317C2 (de)
DK (1) DK139031B (de)
FI (1) FI52587C (de)
FR (1) FR2168006B1 (de)
GB (1) GB1416427A (de)
HU (1) HU167205B (de)
IE (1) IE37048B1 (de)
IL (1) IL41160A (de)
NL (2) NL179287C (de)
PH (1) PH9719A (de)
SE (1) SE411213B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947478A (en) * 1972-01-12 1976-03-30 Akzona Incorporated Alkylated 3,20-diketo-Δ4 -steroids of the pregnane series
GB1436324A (en) * 1972-05-12 1976-05-19 Glaxo Lab Ltd Anaesthetic 3alpha-hydroxy pregnanes
US4031075A (en) * 1973-07-11 1977-06-21 Akzona Incorporated Alkylated pregnanes and process for obtaining same
GB1478968A (en) * 1973-07-11 1977-07-06 Akzo Nv Alkylated pregnanes
JPS5264666A (en) * 1975-11-25 1977-05-28 Sharp Kk Bothhside circuit substrate
EP0014005B1 (de) * 1979-01-24 1983-08-03 Akzo N.V. Alkylierte Pregnane, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS58194A (ja) * 1981-06-25 1983-01-05 北陸電気工業株式会社 Ｃｕ粉末導電塗料を用いた印刷抵抗回路基板の製造方法
US4686214A (en) * 1985-10-30 1987-08-11 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
EP0523132A1 (de) * 1990-03-27 1993-01-20 Schering Corporation Verfahren zur dehydrierung von 9-alpha-hydroxy-steroiden
AU1331097A (en) * 1995-12-20 1997-07-14 Schering Corporation Process for preparation of 9,11beta-epoxide steroids
WO1998018813A1 (en) * 1996-10-25 1998-05-07 Alcon Laboratories, Inc. Method of preparing 21-alkylated pregna-1,4,16-trien-3,20-diones
US6040468A (en) * 1996-10-25 2000-03-21 Alcon Laboratories, Inc. Method of preparing 16α, 17α-dialkylated steroids
PL337458A1 (en) * 1997-06-04 2000-08-14 Akzo Nobel Nv Application of anti-inflammatory steroids in treating chronic intestinal inflammatory diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3064017A (en) * 1962-11-13 Preparation viii
US3047594A (en) * 1960-05-11 1962-07-31 Pfizer & Co C Preparation of 21-methyl steroids and intermediates
US3114750A (en) * 1960-11-07 1963-12-17 British Drug Houses Ltd 3-enol ethers of 6-formyl-3-oxo-delta4-steroids and process for their preparation
US3166551A (en) * 1962-01-02 1965-01-19 British Drug Houses Ltd Process for the preparation of 3-oxo-delta4-6-methyl steroids
DE1167829B (de) * 1962-08-03 1964-04-16 Schering Ag Verfahren zur Herstellung von 21-Methyl-í¸-pregnen-11ª‰, 17ª‡-diol-3, 20-dion
US3594407A (en) * 1969-04-03 1971-07-20 American Home Prod 13,17-dialkyl-19-norpregn-4-ene,3,20-diones

Also Published As

Publication number Publication date
JPS5614678B2 (de) 1981-04-06
PH9719A (en) 1976-02-27
DE2301317A1 (de) 1973-07-26
FR2168006B1 (de) 1976-09-03
NL179287C (nl) 1986-08-18
DK139031B (da) 1978-12-04
NL179287B (nl) 1986-03-17
FI52587B (de) 1977-06-30
FI52587C (fi) 1977-10-10
HU167205B (de) 1975-09-27
IL41160A (en) 1977-04-29
SE411213B (sv) 1979-12-10
US3862194A (en) 1975-01-21
FR2168006A1 (de) 1973-08-24
GB1416427A (en) 1975-12-03
CA1022158A (en) 1977-12-06
ATA28373A (de) 1981-10-15
IE37048B1 (en) 1977-04-27
BE793958A (fr) 1973-07-12
IL41160A0 (en) 1973-02-28
NL7300313A (de) 1973-07-16
DK139031C (de) 1979-05-14
CH615934A5 (de) 1980-02-29
IE37048L (en) 1973-07-12
DE2301317C2 (de) 1983-11-03
NL930031I1 (nl) 1993-07-01
JPS504060A (de) 1975-01-16

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time