CH408910A - Verfahren zur Herstellung von Polyhydrophenanthrenverbindungen - Google Patents

Verfahren zur Herstellung von Polyhydrophenanthrenverbindungen

Info

Publication number
CH408910A
CH408910A CH481662A CH481662A CH408910A CH 408910 A CH408910 A CH 408910A CH 481662 A CH481662 A CH 481662A CH 481662 A CH481662 A CH 481662A CH 408910 A CH408910 A CH 408910A
Authority
CH
Switzerland
Prior art keywords
compound
formula
ether
solution
phenanthrene
Prior art date
Application number
CH481662A
Other languages
German (de)
English (en)
Inventor
Wolf Goldberg Moses
Mischa Jampolsky Lester
Montclair Upper
Wightman Kierstead Richard
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH408910A publication Critical patent/CH408910A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/37—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with a hydroxy group on a condensed system having three rings
    • C07C35/42—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with a hydroxy group on a condensed system having three rings derived from the phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/20—Preparation of ethers by reactions not forming ether-oxygen bonds by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/29—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with halogen-containing compounds which may be formed in situ
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH481662A 1961-05-15 1962-04-19 Verfahren zur Herstellung von Polyhydrophenanthrenverbindungen CH408910A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10988261A 1961-05-15 1961-05-15

Publications (1)

Publication Number Publication Date
CH408910A true CH408910A (de) 1966-03-15

Family

ID=22330073

Family Applications (1)

Application Number Title Priority Date Filing Date
CH481662A CH408910A (de) 1961-05-15 1962-04-19 Verfahren zur Herstellung von Polyhydrophenanthrenverbindungen

Country Status (7)

Country Link
BE (1) BE617616A (fr)
CH (1) CH408910A (fr)
DE (2) DE1518983A1 (fr)
DK (3) DK104457C (fr)
ES (1) ES277295A1 (fr)
FR (1) FR2110M (fr)
GB (1) GB969083A (fr)

Also Published As

Publication number Publication date
DK103183C (da) 1965-11-29
BE617616A (fr) 1962-11-14
FR2110M (fr) 1963-10-28
DE1518983A1 (de) 1969-08-21
DK103073C (da) 1965-11-15
DK104457C (da) 1966-05-23
DE1443986A1 (de) 1969-03-20
GB969083A (en) 1964-09-09
ES277295A1 (es) 1962-10-16

Similar Documents

Publication Publication Date Title
CH408910A (de) Verfahren zur Herstellung von Polyhydrophenanthrenverbindungen
AT233558B (de) Verfahren zur Herstellung von neuen Polyhydrophenanthrenverbindungen
DE2132315C3 (de) Verfahren zur Herstellung der 1 beta, 11 alpha-Dimethyl-1,2,3,4,10 alpha, 11hexahydro-9 beta-hydroxyfluoren-1 alpha, 9alpha-dicarbonsäure aus Abietinsäure
DE1027663B (de) Verfahren zur Herstellung von in 12-Stellung unsubstituierten 11-Oxy-oder 11-Acyloxysteroiden
AT248622B (de) Verfahren zur Herstellung neuer 2-Cyano-3-oxo-steroide
DE825686C (de) Verfahren zur UEberfuehrung von í¸-20-Cyanpregnenen mit einer oder mehreren kerngebundenen Hydroxylgruppen in 17 alpha-Oxy-20-ketopregnane
DE1264441B (de) Verfahren zur Herstellung von 17alpha-AEthinyl-delta 5(10-19-nor-androsten-17beta-ol-3-on und 17alpha-AEthynil-19-nor-testosteron sowie dessen Estern
AT231083B (de) Verfahren zur Herstellung eines neuen 16 α-Methyl-17α-hydroxy-20-ketons der Allopregnanreihe
AT232998B (de) Verfahren zur Herstellung von neuen Polyhydrophenanthrenverbindungen
CH227069A (de) Verfahren zur Herstellung einer Cyclopentano-dimethyl-polyhydrophenanthren-carbonsäure.
AT215089B (de) Verfahren zur Herstellung von 6-Hydroxy-3:5-cyclopregnan-20-on
AT224119B (de) Verfahren zur Isomerisierung von basisch substituierten tricyclischen Verbindungen
AT230367B (de) Verfahren zur Herstellung von neuen Octahydrophenanthrencarbonsäuren
AT160482B (de) Verfahren zur Darstellung von Pregnen-(5)-ol-(3)-on-(20) oder dessen Stereoisomeren bzw. deren Derivaten.
AT273387B (de) Verfahren zur Herstellung von neuen Cholesterinderivaten sowie von deren Säureadditionssalzen
AT241706B (de) Verfahren zur Herstellung von 18, 20-Laktonen der Pregnanreihe
AT219204B (de) Verfahren zur Herstellung von 3-Alkoxy-19-nor-δ<2,5(10)> -androstadien-17-on
AT253704B (de) Verfahren zur Herstellung des neuen 7α-Methyl-16α-hydroxy-östrons und seines 3, 16-Diacetates
US2563846A (en) Cyclopentanoperhydrophenanthrene compounds
AT250581B (de) Verfahren zur Herstellung von 2α-Methylandrostan-Derivaten
AT299169B (de) Verfahren zur Herstellung der neuen α-[p-(1-Cyclohexenyl)-phenyl]-propionsäure
DE1593385C (de) Verfahren zur Herstellung von 18 Oxoverbindungen der 5alpha oder 5beta D Homoandrostanreihe bzw von 3 Methoxy 20 oxo 19 nor 1,3,5(10) pregnatrien 18 al 20 athylenketal Ausscheidung aus 1260466
DE1050765B (de) Verfahren zur Herstellung von Testan-3a-ol-ll-on und seinen Estern
DE1147578B (de) Verfahren zur Herstellung von neuen therapeutisch wirksamen 4'-(17ª‰-Androstanyl)-derivaten von ª†-Valerolactonen oder den homologen ª†-Butyrolactonen
DE1093360B (de) Verfahren zur Herstellung von stabilen antioestrogen wirksamen Verbindungen der Oestranreihe