CA3006367A1 - Wnt pathway stimulation in reprogramming somatic cells - Google Patents

Wnt pathway stimulation in reprogramming somatic cells

Info

Publication number
CA3006367A1
CA3006367A1 CA3006367A CA3006367A CA3006367A1 CA 3006367 A1 CA3006367 A1 CA 3006367A1 CA 3006367 A CA3006367 A CA 3006367A CA 3006367 A CA3006367 A CA 3006367A CA 3006367 A1 CA3006367 A1 CA 3006367A1
Authority
CA
Canada
Prior art keywords
cells
cell
reprogramming
wnt
somatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3006367A
Other languages
English (en)
French (fr)
Inventor
Brett Chevalier
Alexander Marson
Richard A. Young
Ruth Foreman
Rudolf Jaenisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitehead Institute for Biomedical Research
Original Assignee
Whitehead Institute for Biomedical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitehead Institute for Biomedical Research filed Critical Whitehead Institute for Biomedical Research
Publication of CA3006367A1 publication Critical patent/CA3006367A1/en
Abandoned legal-status Critical Current

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/415Wnt; Frizzeled
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/602Sox-2
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/603Oct-3/4
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/604Klf-4
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/45Artificially induced pluripotent stem cells
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    • C12N2502/99Coculture with; Conditioned medium produced by genetically modified cells
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    • C12N2510/00Genetically modified cells

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
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CA3006367A 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells Abandoned CA3006367A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US96702807P 2007-08-31 2007-08-31
US60/967,028 2007-08-31
US18819008P 2008-08-06 2008-08-06
US61/188,190 2008-08-06
CA2698091A CA2698091C (en) 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2698091A Division CA2698091C (en) 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells

Publications (1)

Publication Number Publication Date
CA3006367A1 true CA3006367A1 (en) 2009-03-12

Family

ID=40429192

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3006367A Abandoned CA3006367A1 (en) 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells
CA2698091A Active CA2698091C (en) 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2698091A Active CA2698091C (en) 2007-08-31 2008-08-29 Wnt pathway stimulation in reprogramming somatic cells

Country Status (10)

Country Link
US (6) US9102919B2 (enExample)
EP (2) EP3078738B1 (enExample)
JP (8) JP6151879B2 (enExample)
CN (1) CN101855338B (enExample)
AU (5) AU2008297011B2 (enExample)
CA (2) CA3006367A1 (enExample)
ES (2) ES2589122T3 (enExample)
MX (1) MX2010002242A (enExample)
RU (1) RU2492232C2 (enExample)
WO (1) WO2009032194A1 (enExample)

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