CA2852874A1 - Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof - Google Patents
Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof Download PDFInfo
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- CA2852874A1 CA2852874A1 CA2852874A CA2852874A CA2852874A1 CA 2852874 A1 CA2852874 A1 CA 2852874A1 CA 2852874 A CA2852874 A CA 2852874A CA 2852874 A CA2852874 A CA 2852874A CA 2852874 A1 CA2852874 A1 CA 2852874A1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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Landscapes
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| US201261649717P | 2012-05-21 | 2012-05-21 | |
| US61/649,717 | 2012-05-21 | ||
| PCT/US2012/039004 WO2013058833A1 (en) | 2011-10-19 | 2012-05-22 | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
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| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| CA2967851C (en) | 2014-12-05 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Treating seizure with recombinant alkaline phosphatase |
| US10603361B2 (en) | 2015-01-28 | 2020-03-31 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
| JP6693134B2 (ja) * | 2015-02-02 | 2020-05-13 | 東ソー株式会社 | リンカー配列を有する抗体及びそれを用いた測定法 |
| HK1250040A1 (zh) | 2015-03-31 | 2018-11-23 | Sorriso Pharmaceuticals, Inc. | 多肽 |
| CA2981098A1 (en) * | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Peptide construct having a protease-cleavable linker |
| JP6895421B2 (ja) | 2015-03-31 | 2021-06-30 | ブイエイチスクエアード リミテッド | ポリペプチド |
| TWI773649B (zh) | 2015-07-30 | 2022-08-11 | 美商拜奧馬林製藥公司 | C型利尿納肽變異體治療骨骼發育不良之用途 |
| RU2745528C2 (ru) | 2015-08-17 | 2021-03-26 | Алексион Фармасьютикалз, Инк. | Производство щелочных фосфатаз |
| WO2017058822A1 (en) * | 2015-09-28 | 2017-04-06 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
| WO2017074466A1 (en) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
| EP3426286A4 (en) | 2016-03-08 | 2019-12-04 | Alexion Pharmaceuticals, Inc. | PROCESS FOR TREATING HYPOPHOSPHATASIA IN CHILDREN |
| JP7613826B2 (ja) * | 2016-04-01 | 2025-01-15 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼによって筋力低下を治療すること |
| EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | METHOD FOR TREATING HYPOPHOSPHATASIE IN TEENS AND ADULTS |
| KR102449167B1 (ko) * | 2016-05-06 | 2022-09-28 | 파세비오 파마수티컬스 인코포레이티드 | 제어된 지속 방출을 위한 elp 융합 단백질 |
| US10988744B2 (en) | 2016-06-06 | 2021-04-27 | Alexion Pharmaceuticals, Inc. | Method of producing alkaline phosphatase |
| EP3500289B1 (en) * | 2016-08-18 | 2024-10-09 | Alexion Pharmaceuticals, Inc. | Asfotase alfa for use in treating tracheobronchomalacia |
| EP3519438A1 (en) | 2016-09-30 | 2019-08-07 | VHsquared Limited | Compositions |
| TW202506185A (zh) | 2017-01-20 | 2025-02-16 | 法商賽諾菲公司 | 抗TGF-β抗體及其用途 |
| AR110755A1 (es) * | 2017-01-20 | 2019-05-02 | Genzyme Corp | Anticuerpos dirigidos a hueso |
| CA3057502A1 (en) | 2017-03-31 | 2018-10-04 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia (hpp) in adults and adolescents |
| EP3737750B1 (en) | 2018-01-09 | 2024-06-05 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of neurodevelopmental disorders |
| US11638699B2 (en) | 2018-03-20 | 2023-05-02 | Theriva Biologics, Inc. | Intestinal alkaline phosphatase formulations |
| WO2019183209A1 (en) | 2018-03-20 | 2019-09-26 | Synthetic Biologics, Inc. | Alkaline phosphatase agents for treatment of radiation disorders |
| JP2021519590A (ja) | 2018-03-30 | 2021-08-12 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 糖タンパク質の製造 |
| JP2021534111A (ja) | 2018-08-10 | 2021-12-09 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼを用いて神経線維腫症1型および関連状態を治療する方法 |
| CA3137045A1 (en) | 2019-05-06 | 2020-11-12 | Synthetic Biologics, Inc. | Alkaline phosphate-based oncology treatments |
| AU2020294980A1 (en) | 2019-06-21 | 2022-02-17 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| EP3986931A1 (en) | 2019-06-21 | 2022-04-27 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| US12433938B2 (en) * | 2019-12-09 | 2025-10-07 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
| WO2022051555A2 (en) * | 2020-09-03 | 2022-03-10 | Rampart Bioscience, Inc. | Soluble alkaline phosphatase constructs and expression vectors including a polynucleotide encoding for soluble alkaline phosphatase constructs |
| AU2022218782A1 (en) | 2021-02-12 | 2023-08-17 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
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| CN116286763B (zh) * | 2023-02-28 | 2024-06-25 | 西北工业大学 | 一种热稳定性提高的胱硫醚β-合成酶突变体及应用 |
| TW202513806A (zh) * | 2023-06-07 | 2025-04-01 | 美商拜奧馬林製藥公司 | 高通量篩選與身材矮小相關之基因變異體 |
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| US5352770A (en) | 1990-04-20 | 1994-10-04 | Hisayuki Matsuo | Porcine derived novel physiologically active peptide |
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| PL2158319T4 (pl) * | 2007-05-11 | 2016-04-29 | Alexion Pharma Inc | Fosfataza alkaliczna kierowana do kości, zestawy i zastosowanie |
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| PT2765139T (pt) | 2007-07-20 | 2017-07-14 | Mayo Foundation | Polipéptidos natriuréticos |
| KR20100056517A (ko) * | 2007-09-11 | 2010-05-27 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 펩티드의 용도 |
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| HRP20161739T1 (hr) | 2009-05-20 | 2017-03-10 | Biomarin Pharmaceutical Inc. | VARIJANTE NATRIURETIČNOG PEPTIDA C-tipa |
-
2012
- 2012-05-22 SG SG11201401605QA patent/SG11201401605QA/en unknown
- 2012-05-22 WO PCT/US2012/039004 patent/WO2013058833A1/en not_active Ceased
- 2012-05-22 CA CA2852874A patent/CA2852874A1/en not_active Abandoned
- 2012-05-22 KR KR1020147013214A patent/KR20140084201A/ko not_active Withdrawn
- 2012-10-18 ES ES12842640T patent/ES2714406T3/es active Active
- 2012-10-18 WO PCT/US2012/060869 patent/WO2013059491A1/en not_active Ceased
- 2012-10-18 ES ES18201378T patent/ES2944087T3/es active Active
- 2012-10-18 EP EP12842640.0A patent/EP2768526B1/en active Active
- 2012-10-18 HK HK15101938.6A patent/HK1201446A1/xx unknown
- 2012-10-18 JP JP2014537254A patent/JP6118807B2/ja active Active
- 2012-10-18 EP EP18201378.9A patent/EP3488861B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6118807B2 (ja) | 2017-04-19 |
| EP2768526A1 (en) | 2014-08-27 |
| EP2768526B1 (en) | 2018-12-05 |
| WO2013058833A8 (en) | 2013-06-13 |
| ES2944087T3 (es) | 2023-06-19 |
| WO2013058833A1 (en) | 2013-04-25 |
| EP3488861B1 (en) | 2023-02-15 |
| EP3488861A1 (en) | 2019-05-29 |
| KR20140084201A (ko) | 2014-07-04 |
| EP2768526A4 (en) | 2015-04-15 |
| JP2015502336A (ja) | 2015-01-22 |
| ES2714406T3 (es) | 2019-05-28 |
| HK1201446A1 (en) | 2015-09-04 |
| SG11201401605QA (en) | 2014-09-26 |
| WO2013059491A1 (en) | 2013-04-25 |
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