CA2700410C - Treatment of proliferative disorders using antibodies to psma - Google Patents
Treatment of proliferative disorders using antibodies to psma Download PDFInfo
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- CA2700410C CA2700410C CA2700410A CA2700410A CA2700410C CA 2700410 C CA2700410 C CA 2700410C CA 2700410 A CA2700410 A CA 2700410A CA 2700410 A CA2700410 A CA 2700410A CA 2700410 C CA2700410 C CA 2700410C
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- psma
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- antigen binding
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Microbiology (AREA)
- Mycology (AREA)
- Gynecology & Obstetrics (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PCT/US2008/078742 WO2009046294A2 (en) | 2007-10-03 | 2008-10-03 | Treatment of proliferative disorders using antibodies to psma |
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| CA2700410C true CA2700410C (en) | 2020-10-06 |
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| US20120183847A1 (en) | 2009-05-19 | 2012-07-19 | Aic Blab | Composite current collector and methods therefor |
| EP2817629A4 (en) * | 2012-02-24 | 2016-01-13 | Univ Cornell | INCREASED PSMA VALUE AS IDENTIFIER OF DEADLY PROSTATE CANCER |
| HK1202256A1 (en) * | 2012-02-28 | 2015-09-25 | Cornell University | Psma as a biomarker for androgen activity in prostate cancer |
| CA2887047A1 (en) * | 2012-10-05 | 2014-04-10 | Cornell University | Androgen suppression, prostate-specific membrane antigen and the concept of conditionally enhanced vulnerability |
| MA41046A (fr) * | 2014-10-10 | 2017-08-15 | Memorial Sloan Kettering Cancer Center | Thérapies liées au psma |
| US20180022819A1 (en) * | 2015-02-11 | 2018-01-25 | Aptevo Research And Development Llc | Compositions and methods for combination therapy with prostate-specific membrane antigen binding proteins |
| EP3352760A4 (en) | 2015-09-21 | 2019-03-06 | Aptevo Research and Development LLC | CD3-BINDING POLYPEPTIDES |
| EP3609544B1 (en) * | 2017-04-11 | 2025-04-09 | The Johns Hopkins University | Prodrugs of 2-pmpa for healthy tissue protection during psma-targeted cancer imaging or radiotherapy |
| US12491255B2 (en) | 2019-10-14 | 2025-12-09 | Aro Biotherapeutics Company | EPCAM binding fibronectin type III domains |
| CA3177330A1 (en) * | 2020-05-05 | 2021-11-11 | Aro Biotherapeutics Company | Prostate specific membrane antigen binding fibronectin type iii domains and cells comprising the same |
| CA3188601A1 (en) | 2020-07-08 | 2022-01-13 | LAVA Therapeutics N.V. | Antibodies that bind psma and gamma-delta t cell receptors |
| JP2024517610A (ja) | 2021-04-14 | 2024-04-23 | アロ・バイオセラピューティクス・カンパニー | Ｃｄ７１に結合するフィブロネクチンｉｉｉ型ドメイン |
| EP4323008A1 (en) | 2021-04-14 | 2024-02-21 | ARO Biotherapeutics Company | Fn3 domain-sirna conjugates and uses thereof |
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- 2008-10-03 EP EP14157123.2A patent/EP2740490A1/en not_active Ceased
- 2008-10-03 EP EP20152859.3A patent/EP3714906A1/en active Pending
- 2008-10-03 US US12/681,341 patent/US20100291113A1/en not_active Abandoned
- 2008-10-03 CA CA2700410A patent/CA2700410C/en active Active
- 2008-10-03 WO PCT/US2008/078742 patent/WO2009046294A2/en not_active Ceased
-
2013
- 2013-10-02 JP JP2013207386A patent/JP5969446B2/ja active Active
-
2014
- 2014-11-10 US US14/537,002 patent/US20150056135A1/en not_active Abandoned
-
2016
- 2016-01-14 JP JP2016005363A patent/JP6054557B2/ja active Active
-
2018
- 2018-04-30 US US15/966,961 patent/US20190070322A1/en not_active Abandoned
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2024
- 2024-04-19 US US18/641,102 patent/US20250058000A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2209498A2 (en) | 2010-07-28 |
| WO2009046294A3 (en) | 2010-03-04 |
| EP2740490A1 (en) | 2014-06-11 |
| US20190070322A1 (en) | 2019-03-07 |
| US20150056135A1 (en) | 2015-02-26 |
| JP5951929B2 (ja) | 2016-07-13 |
| JP6054557B2 (ja) | 2016-12-27 |
| JP2010540657A (ja) | 2010-12-24 |
| JP2016147848A (ja) | 2016-08-18 |
| CA2700410A1 (en) | 2009-04-09 |
| US20250058000A1 (en) | 2025-02-20 |
| US20100291113A1 (en) | 2010-11-18 |
| EP3714906A1 (en) | 2020-09-30 |
| JP2014040450A (ja) | 2014-03-06 |
| WO2009046294A2 (en) | 2009-04-09 |
| JP5969446B2 (ja) | 2016-08-17 |
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