CA2667043A1 - Multiple mutation variants of serine protease - Google Patents
Multiple mutation variants of serine protease Download PDFInfo
- Publication number
- CA2667043A1 CA2667043A1 CA002667043A CA2667043A CA2667043A1 CA 2667043 A1 CA2667043 A1 CA 2667043A1 CA 002667043 A CA002667043 A CA 002667043A CA 2667043 A CA2667043 A CA 2667043A CA 2667043 A1 CA2667043 A1 CA 2667043A1
- Authority
- CA
- Canada
- Prior art keywords
- protease
- variant
- amino acid
- acid sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 108010022999 Serine Proteases Proteins 0.000 title claims abstract description 107
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
- D06M16/003—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic with enzymes or microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Textile Engineering (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58333406A | 2006-10-19 | 2006-10-19 | |
| US11/583,334 | 2006-10-19 | ||
| US11/809,104 | 2007-05-31 | ||
| US11/809,104 US7985569B2 (en) | 2003-11-19 | 2007-05-31 | Cellulomonas 69B4 serine protease variants |
| PCT/US2007/018909 WO2008048392A1 (en) | 2006-10-19 | 2007-08-29 | Multiple mutation variants of serine protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2667043A1 true CA2667043A1 (en) | 2008-04-24 |
Family
ID=38982619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002667043A Abandoned CA2667043A1 (en) | 2006-10-19 | 2007-08-29 | Multiple mutation variants of serine protease |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US7985569B2 (https=) |
| EP (1) | EP2084273A1 (https=) |
| JP (1) | JP5775666B2 (https=) |
| KR (2) | KR20090075825A (https=) |
| BR (1) | BRPI0718483A2 (https=) |
| CA (1) | CA2667043A1 (https=) |
| MX (1) | MX2009003936A (https=) |
| RU (1) | RU2558261C2 (https=) |
| WO (1) | WO2008048392A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ATE450606T1 (de) * | 2002-01-16 | 2009-12-15 | Genencor Int | Mehrfachsubstituierte proteasevarianten |
| MXPA04006811A (es) * | 2002-01-16 | 2004-10-11 | Genencor Int | Variantes de proteasa substituidas con multiplos. |
| JP5785686B2 (ja) * | 2006-06-23 | 2015-09-30 | ダニスコ・ユーエス・インク、ジェネンコー・ディビジョン | 複数の性質をエンジニアリングするための部位評価ライブラリーを用いた、配列と活性との関係の系統的な評価 |
| WO2008044016A1 (en) * | 2006-10-14 | 2008-04-17 | Reckitt Benckiser N.V. | Composition |
| EP2118121A1 (en) * | 2007-03-01 | 2009-11-18 | Novo Nordisk A/S | Expression of proteins in e. coli |
| CN101889084A (zh) * | 2007-12-04 | 2010-11-17 | 诺维信公司 | 供药学应用的蛋白酶变体 |
| US20090209447A1 (en) * | 2008-02-15 | 2009-08-20 | Michelle Meek | Cleaning compositions |
| MX2010009457A (es) * | 2008-02-29 | 2010-09-24 | Procter & Gamble | Composicion detergente que comprende lipasa. |
| WO2009107091A2 (en) * | 2008-02-29 | 2009-09-03 | The Procter & Gamble Company | Detergent composition comprising lipase |
| EP2100947A1 (en) | 2008-03-14 | 2009-09-16 | The Procter and Gamble Company | Automatic dishwashing detergent composition |
| US20090233830A1 (en) | 2008-03-14 | 2009-09-17 | Penny Sue Dirr | Automatic detergent dishwashing composition |
| EP2166073A1 (en) * | 2008-09-23 | 2010-03-24 | The Procter & Gamble Company | Cleaning composition |
| EP2166075A1 (en) * | 2008-09-23 | 2010-03-24 | The Procter and Gamble Company | Cleaning composition |
| US8096062B1 (en) * | 2008-10-08 | 2012-01-17 | Bellen Mark L | Towel drying system |
| US20100125046A1 (en) | 2008-11-20 | 2010-05-20 | Denome Frank William | Cleaning products |
| US20140014137A1 (en) | 2009-09-18 | 2014-01-16 | Ecolab Usa Inc. | Treatment of non-trans fats with acidic tetra sodium l-glutamic acid, n, n-diacetic acid (glda) |
| MX2012006616A (es) | 2009-12-09 | 2012-06-21 | Procter & Gamble | Productos para el cuidado de las telas y el hogar. |
| EP2380478A1 (en) | 2010-04-23 | 2011-10-26 | The Procter & Gamble Company | Automatic dishwashing product |
| ES2682051T3 (es) | 2010-04-23 | 2018-09-18 | The Procter & Gamble Company | Composición detergente |
| ES2565192T3 (es) | 2010-04-23 | 2016-04-01 | The Procter & Gamble Company | Método para perfumar |
| ES2533368T3 (es) | 2010-04-23 | 2015-04-09 | The Procter & Gamble Company | Producto para lavavajillas |
| EP2383329A1 (en) | 2010-04-23 | 2011-11-02 | The Procter & Gamble Company | Particle |
| EP2380962B1 (en) | 2010-04-23 | 2016-03-30 | The Procter and Gamble Company | Particle |
| EP3095861B1 (en) | 2010-05-06 | 2019-06-26 | The Procter and Gamble Company | Consumer products with protease variants |
| FI123425B (fi) * | 2011-03-31 | 2013-04-30 | Ab Enzymes Oy | Proteaasientsyymi ja sen käytöt |
| ES2834102T3 (es) | 2011-06-30 | 2021-06-16 | Novozymes As | Variantes de alfa-amilasa |
| BR112014017919A2 (pt) | 2012-01-26 | 2017-06-27 | Novozymes As | uso de um poliptídeo variante, composição, polinucleotídeo isolado, constructo de ácido nucleico ou vetor de expressão, célula hospedeira de expressão recombinante, métodos de produção do pilipeptídeo, para melhoria do valor nutricional de uma ração animal, e para o tratamento de proteínas, planta, parte de planta ou célula de planta transgênica, aditivo de ração animal, ração animal, e, composição de ração animal ou detergente |
| ES2599504T3 (es) | 2012-05-30 | 2017-02-02 | Clariant International Ltd | Utilización de N-metil-N-acil-glucaminas como agentes solubilizantes |
| IN2014DN09937A (https=) | 2012-05-30 | 2015-08-14 | Clariant Int Ltd | |
| EP2866895B1 (de) * | 2012-05-30 | 2016-08-31 | Clariant International Ltd | Tensidlösungen mit n-methyl-n-oleylglucamin und n-methyl-n-c12-c14-acylglucamin |
| AU2013279440B2 (en) | 2012-06-20 | 2016-10-06 | Novozymes A/S | Use of polypeptides having protease activity in animal feed and detergents |
| US10253281B2 (en) | 2012-08-20 | 2019-04-09 | Ecolab Usa Inc. | Method of washing textile articles |
| DE102012021647A1 (de) | 2012-11-03 | 2014-05-08 | Clariant International Ltd. | Wässrige Adjuvant-Zusammensetzungen |
| AU2014214032A1 (en) | 2013-02-06 | 2015-07-09 | Novozymes A/S | Use of polypeptides having protease activity in animal feed |
| US20160068620A1 (en) | 2013-03-15 | 2016-03-10 | Lubrizol Advanced Materials, Inc. | Itaconic Acid Polymers |
| WO2015042013A1 (en) | 2013-09-18 | 2015-03-26 | Lubrizol Advanced Materials, Inc. | Stable linear polymers |
| BR112016021154A2 (pt) | 2014-03-14 | 2021-08-24 | Lubrizol Advanced Materials, Inc. | Polímeros e copolímeros de ácido itacônico |
| DE102014005771A1 (de) | 2014-04-23 | 2015-10-29 | Clariant International Ltd. | Verwendung von wässrigen driftreduzierenden Zusammensetzungen |
| CN106687572A (zh) | 2014-09-10 | 2017-05-17 | 巴斯夫欧洲公司 | 包封清洁组合物 |
| BR112017009320A2 (pt) | 2014-11-04 | 2017-12-19 | Novozymes As | ração animal ou aditivo de ração animal, uso de ração animal ou aditivo de ração animal, e, métodos para preparação de uma ração animal, para melhoria do valor nutricional de uma ração animal, para tratamento de proteínas aumento da digestibilidade e/ou solubilidade da proteína, para melhoria de um ou mais parâmetros de desempenho em um animal e para produção de um polipeptídeo. |
| EP3034596B2 (en) | 2014-12-17 | 2021-11-10 | The Procter & Gamble Company | Detergent composition |
| EP3034590A1 (en) | 2014-12-17 | 2016-06-22 | The Procter and Gamble Company | Method of automatic dishwashing |
| EP3034591A1 (en) | 2014-12-17 | 2016-06-22 | The Procter and Gamble Company | Method of automatic dishwashing |
| ES2733300T3 (es) | 2014-12-17 | 2019-11-28 | Procter & Gamble | Composición detergente |
| EP3034592A1 (en) | 2014-12-17 | 2016-06-22 | The Procter and Gamble Company | Method of automatic dishwashing |
| EP3034597A1 (en) | 2014-12-17 | 2016-06-22 | The Procter and Gamble Company | Detergent composition |
| EP3034589A1 (en) | 2014-12-17 | 2016-06-22 | The Procter and Gamble Company | Detergent composition |
| ES2795009T3 (es) * | 2015-01-29 | 2020-11-20 | Ecolab Usa Inc | Método para el tratamiento de manchas en textiles |
| EP3259350A4 (en) | 2015-02-16 | 2018-11-07 | Ozymes | Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof |
| WO2016140703A1 (en) | 2015-03-05 | 2016-09-09 | Crossford International, Llc | Systems and methods for tabletized tube cleaning |
| DE102015219608B4 (de) | 2015-10-09 | 2018-05-03 | Clariant International Ltd | Universelle Pigmentdispersionen auf Basis von N-Alkylglukaminen |
| DE102015219651A1 (de) | 2015-10-09 | 2017-04-13 | Clariant International Ltd. | Zusammensetzungen enthaltend Zuckeramin und Fettsäure |
| US20190085273A1 (en) | 2016-03-09 | 2019-03-21 | Basf Se | Encapsulated laundry cleaning composition |
| KR101978828B1 (ko) * | 2016-03-21 | 2019-05-15 | 주식회사 엘지생활건강 | 바이오필름 제거용 조성물 |
| DE102016207877A1 (de) | 2016-05-09 | 2017-11-09 | Clariant International Ltd | Stabilisatoren für Silikatfarben |
| MX2019007335A (es) * | 2016-12-21 | 2019-09-09 | Dupont Nutrition Biosci Aps | Métodos para usar serina proteasas termoestables. |
| KR102316445B1 (ko) * | 2019-11-29 | 2021-10-26 | 씨제이제일제당 주식회사 | 신규 세린 프로테아제 변이체 |
| KR102613549B1 (ko) | 2021-03-12 | 2023-12-13 | 씨제이제일제당 주식회사 | 신규 세린 프로테아제 변이체 |
| JP7842216B2 (ja) | 2021-12-16 | 2026-04-07 | ザ プロクター アンド ギャンブル カンパニー | プロテアーゼを含む自動食器洗浄組成物 |
| CN115717135B (zh) * | 2022-08-18 | 2024-07-16 | 天津科技大学 | 一种耐热木糖苷酶突变体及其制备 |
| KR20240175756A (ko) * | 2023-06-13 | 2024-12-23 | 씨제이제일제당 (주) | 신규 세린 프로테아제 변이체 |
| KR20250054900A (ko) * | 2023-10-16 | 2025-04-24 | 씨제이제일제당 (주) | 신규 세린 프로테아제 변이체 |
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| US3840433A (en) | 1968-09-23 | 1974-10-08 | Novo Terapeutisk Labor As | Dehairing of leather |
| GB1296839A (https=) | 1969-05-29 | 1972-11-22 | ||
| GB1372034A (en) | 1970-12-31 | 1974-10-30 | Unilever Ltd | Detergent compositions |
| ES421535A1 (es) | 1973-01-13 | 1976-06-16 | Roehm Gmbh | Procedimiento para la preparacion de pellejos dispuestos para curtir a partir de cuero y pieles de origen animal. |
| DE3005845A1 (de) | 1980-02-16 | 1981-09-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Aminosaeure- und peptidester von leuko-indoanilinen, verfahren zu deren herstellung sowie diese verbindungen enthaltende mittel zum nachweis proteolytischer enzyme |
| DK187280A (da) | 1980-04-30 | 1981-10-31 | Novo Industri As | Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode |
| GR76237B (https=) | 1981-08-08 | 1984-08-04 | Procter & Gamble | |
| JPS58144105A (ja) | 1982-02-12 | 1983-08-27 | Kurabo Ind Ltd | スケ−ル除去獣毛繊維の製法 |
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
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-
2007
- 2007-05-31 US US11/809,104 patent/US7985569B2/en not_active Expired - Fee Related
- 2007-08-29 WO PCT/US2007/018909 patent/WO2008048392A1/en not_active Ceased
- 2007-08-29 KR KR1020097007937A patent/KR20090075825A/ko not_active Ceased
- 2007-08-29 EP EP07837430A patent/EP2084273A1/en not_active Withdrawn
- 2007-08-29 RU RU2009118608/10A patent/RU2558261C2/ru not_active IP Right Cessation
- 2007-08-29 JP JP2009533297A patent/JP5775666B2/ja not_active Expired - Fee Related
- 2007-08-29 CA CA002667043A patent/CA2667043A1/en not_active Abandoned
- 2007-08-29 MX MX2009003936A patent/MX2009003936A/es active IP Right Grant
- 2007-08-29 BR BRPI0718483-2A2A patent/BRPI0718483A2/pt not_active IP Right Cessation
- 2007-08-29 KR KR1020147028525A patent/KR20140136033A/ko not_active Ceased
-
2011
- 2011-06-16 US US13/162,104 patent/US8455234B2/en not_active Expired - Fee Related
-
2013
- 2013-05-06 US US13/888,300 patent/US8865449B2/en not_active Expired - Fee Related
-
2014
- 2014-09-11 US US14/483,375 patent/US20150072913A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009003936A (es) | 2009-04-23 |
| KR20090075825A (ko) | 2009-07-09 |
| EP2084273A1 (en) | 2009-08-05 |
| RU2558261C2 (ru) | 2015-07-27 |
| US8455234B2 (en) | 2013-06-04 |
| US7985569B2 (en) | 2011-07-26 |
| US20080063774A1 (en) | 2008-03-13 |
| US20150072913A1 (en) | 2015-03-12 |
| BRPI0718483A2 (pt) | 2013-11-26 |
| WO2008048392A1 (en) | 2008-04-24 |
| JP5775666B2 (ja) | 2015-09-09 |
| JP2010506590A (ja) | 2010-03-04 |
| US20110251116A1 (en) | 2011-10-13 |
| KR20140136033A (ko) | 2014-11-27 |
| RU2009118608A (ru) | 2010-11-27 |
| US20140005094A1 (en) | 2014-01-02 |
| US8865449B2 (en) | 2014-10-21 |
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