CA2467719C - Anti-il-6 antibodies, compositions, methods and uses - Google Patents

Anti-il-6 antibodies, compositions, methods and uses Download PDF

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Publication number
CA2467719C
CA2467719C CA2467719A CA2467719A CA2467719C CA 2467719 C CA2467719 C CA 2467719C CA 2467719 A CA2467719 A CA 2467719A CA 2467719 A CA2467719 A CA 2467719A CA 2467719 C CA2467719 C CA 2467719C
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Canada
Prior art keywords
antibody
human
seq
antibodies
cell
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Expired - Lifetime
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CA2467719A
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English (en)
French (fr)
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CA2467719A1 (en
Inventor
Jill Giles-Komar
David Knight
David Peritt
Mohit Trikha
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Recordati UK Ltd
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Janssen Biotech Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
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    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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