CA1279328C - Process for preparing basic thioethers and the salts thereof - Google Patents

Process for preparing basic thioethers and the salts thereof

Info

Publication number
CA1279328C
CA1279328C CA000458870A CA458870A CA1279328C CA 1279328 C CA1279328 C CA 1279328C CA 000458870 A CA000458870 A CA 000458870A CA 458870 A CA458870 A CA 458870A CA 1279328 C CA1279328 C CA 1279328C
Authority
CA
Canada
Prior art keywords
formula
process according
hydrochloride
monohydrochloride
dihydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000458870A
Other languages
English (en)
French (fr)
Inventor
Janos Borvendeg
Eszter Diesler
Beata Vitalis
Endre Kasztreiner
Peter Matyus
Antal Szabo
Oszkar Fuchs
Judit Kosary
Arpad Lazar
Lajos Toldy
Jozsef Engler
Tibor Lang
Tibor Somogyi
Nandor Makk
Tibor Balogh
Bela Stefko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU251583A external-priority patent/HU193497B/hu
Priority claimed from HU251483A external-priority patent/HU193496B/hu
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of CA1279328C publication Critical patent/CA1279328C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA000458870A 1983-07-15 1984-07-13 Process for preparing basic thioethers and the salts thereof Expired - Fee Related CA1279328C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU2514/83 1983-07-15
HU2515/83 1983-07-15
HU251583A HU193497B (en) 1983-07-15 1983-07-15 Process for preparing sanitidine hydrogen halogenides
HU251483A HU193496B (en) 1983-07-15 1983-07-15 Process for production of basic tioether and it salts i

Publications (1)

Publication Number Publication Date
CA1279328C true CA1279328C (en) 1991-01-22

Family

ID=26317525

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000458870A Expired - Fee Related CA1279328C (en) 1983-07-15 1984-07-13 Process for preparing basic thioethers and the salts thereof

Country Status (13)

Country Link
KR (1) KR910007966B1 (sv)
AR (1) AR242029A1 (sv)
AT (1) AT389873B (sv)
CA (1) CA1279328C (sv)
CS (1) CS248717B2 (sv)
DK (1) DK162525C (sv)
ES (1) ES8602732A1 (sv)
FI (1) FI88157C (sv)
MX (1) MX159694A (sv)
NO (1) NO842904L (sv)
SE (1) SE457082B (sv)
SU (1) SU1384197A3 (sv)
YU (1) YU45634B (sv)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
BE886997A (fr) * 1980-01-08 1981-07-08 Glaxo Group Ltd Procede de preparation de la ranitidine et produits intermediaires de cette preparation
NO811501L (no) * 1980-05-13 1981-11-16 Crc Ricerca Chim Fremgangsmaate ved fremstilling av etendiaminderivater, samt mellomprodukter for disse
ES495493A0 (es) * 1980-09-30 1981-11-01 Inke Sa Ÿprocedimiento para la obtencion de la n-2-5-(dimetilamino)metil-2-furanil metil tio-n-metil-2-nitro-1,1-etenodiaminaÿ.
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
ES497386A0 (es) * 1980-12-03 1981-10-16 Inke Sa Procedimiento para la obtencion de la n-(2-( ( (5-( (dimeti-lamino)metil)-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-etenodiamina
ES8200674A1 (es) * 1980-12-13 1981-11-16 Parellada Llauger Miguel Procedimiento para la obtencion de la n-(2-((5-((dimetilami-no)metil)furfuril)tio)etil)-n'- metil -2- nitro-1,1- eteno- diamina
DE3170346D1 (en) * 1980-12-30 1985-06-05 Glaxo Group Ltd Process for the preparation of a furan derivative
JPS57134476A (en) * 1980-12-30 1982-08-19 Glaxo Group Ltd Manufacture of furan derivatives
AR226777A1 (es) * 1981-02-20 1982-08-13 Glaxo Group Ltd Un procedimiento para la preparacion de ranitidina
ES8300325A1 (es) * 1981-05-02 1982-11-01 Especialidades Farmaco Terape Procedimiento para la obtencion de un compuesto derivado delalcohol furfurilico
AR229878A1 (es) * 1981-05-07 1983-12-30 Glaxo Group Ltd Procedimiento para preparar ranitidina
ES8300732A1 (es) * 1981-06-10 1982-11-01 Lafarquim Procedimiento para la obtencion de derivados de furil metil mercaptano y sus sales de interes farmacologico
ES8301226A1 (es) * 1981-11-20 1982-11-16 Especialidades Latinas Medic U Procedimiento de obtencion de n-(2-5-dimetilamino,metil-2-furanil-metil-tio-etil-n'-metil-s-nitro-etano-diamina.
ES508693A0 (es) * 1982-01-13 1982-11-01 Barisintex Sa "procedimiento para la obtencion de derivados de aminoalkilfuranos".
ES511830A0 (es) * 1982-04-30 1983-02-01 Inke Sa Procedimiento para la obtencion de la n-2-(5-(dimetilanmino)metil-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-eteno- diamina.
ES8302686A1 (es) * 1982-05-19 1983-02-01 Tabah Papo Marcelo Procedimiento para la obtencion de un nuevo derivado furanico de interes terapeutico.

Also Published As

Publication number Publication date
KR910007966B1 (ko) 1991-10-04
FI88157C (sv) 1993-04-13
ES534363A0 (es) 1985-12-01
DK162525B (da) 1991-11-11
KR850001187A (ko) 1985-03-16
NO842904L (no) 1985-01-16
SE8403717D0 (sv) 1984-07-13
DK345284A (da) 1985-01-16
SU1384197A3 (ru) 1988-03-23
ES8602732A1 (es) 1985-12-01
CS248717B2 (en) 1987-02-12
YU45634B (sh) 1992-07-20
FI842822A0 (fi) 1984-07-13
SE457082B (sv) 1988-11-28
DK345284D0 (da) 1984-07-13
MX159694A (es) 1989-08-07
FI842822A (fi) 1985-01-16
DK162525C (da) 1992-03-30
YU122484A (sv) 1986-10-31
ATA227284A (de) 1989-07-15
AT389873B (de) 1990-02-12
SE8403717L (sv) 1985-01-16
FI88157B (fi) 1992-12-31
AR242029A1 (es) 1993-02-26

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Legal Events

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